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Volumn 88, Issue 2-3, 2012, Pages 223-236

Profiles of motor and cognitive impairment in the transgenic rat model of Huntington's disease

Author keywords

Cognitive tests; Frontostriatal function; Huntingtin inclusions; Motor tests; Phenotype; TgHD rats

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COGNITIVE DEFECT; CONTROLLED STUDY; DELAYED ALTERNATION; EXPERIMENTAL TEST; EXPLORATION OF NOVELTY TEST; FEMALE; HETEROZYGOTE; HOMOZYGOTE; HUNTINGTON CHOREA; MALE; MOTOR DYSFUNCTION; NONHUMAN; OBJECT RECOGNITION TEST; PRIORITY JOURNAL; RAT; RESPONSE TIME; ROTAROD TEST; SERIAL IMPLICIT LEARNING TASK; SEX DIFFERENCE; STAIRCASE REACHING TEST; TRANSGENIC HUNTINGTON DISEASE RAT; TRANSGENIC RAT; WILD TYPE;

EID: 84860835558     PISSN: 03619230     EISSN: 18732747     Source Type: Journal    
DOI: 10.1016/j.brainresbull.2011.09.011     Document Type: Article
Times cited : (22)

References (68)
  • 1
    • 0003155081 scopus 로고
    • Skilled paw reaching in rats: the staircase test
    • Abrous D.N., Dunnett S.B. Skilled paw reaching in rats: the staircase test. Neurosci. Prot. 1994, 3:1-11.
    • (1994) Neurosci. Prot. , vol.3 , pp. 1-11
    • Abrous, D.N.1    Dunnett, S.B.2
  • 2
    • 84882921634 scopus 로고    scopus 로고
    • Animal models of Huntington's disease
    • in: L.R. Squire (Ed.), Encyclopedia of Neuroscience, Amsterdam
    • J. Alberch, E. Pérez-Navarro, J.M. Canals, Animal models of Huntington's disease, in: L.R. Squire (Ed.), Encyclopedia of Neuroscience, Amsterdam, 2009, pp. 429-436.
    • (2009) , pp. 429-436
    • Alberch, J.1    Pérez-Navarro, E.2    Canals, J.M.3
  • 3
    • 23244437460 scopus 로고    scopus 로고
    • Regional and subtype selective changes of neurotransmitter receptor density in a rat transgenic for the Huntington's disease mutation
    • Bauer A., Zilles K., Matusch A., Holzmann C., Riess O., von Hörsten S. Regional and subtype selective changes of neurotransmitter receptor density in a rat transgenic for the Huntington's disease mutation. J. Neurochem. 2005, 94:639-650.
    • (2005) J. Neurochem. , vol.94 , pp. 639-650
    • Bauer, A.1    Zilles, K.2    Matusch, A.3    Holzmann, C.4    Riess, O.5    von Hörsten, S.6
  • 4
    • 84860837080 scopus 로고    scopus 로고
    • Light and electron microscopic characterisation of the evolution of cellular pathology in the R6/1 Huntington's disease transgenic mice
    • Bayram-Weston Z., Jones L., Dunnett S.B., Brooks S.P. Light and electron microscopic characterisation of the evolution of cellular pathology in the R6/1 Huntington's disease transgenic mice. Brain Res. Bull. 2012, 88:104-112.
    • (2012) Brain Res. Bull. , vol.88 , pp. 104-112
    • Bayram-Weston, Z.1    Jones, L.2    Dunnett, S.B.3    Brooks, S.P.4
  • 5
    • 84860836853 scopus 로고    scopus 로고
    • Light and electron microscopic characterisation of the evolution of cellular pathology in the YAC128 transgenic mice
    • Bayram-Weston Z., Jones L., Dunnett S.B., Brooks S.P. Light and electron microscopic characterisation of the evolution of cellular pathology in the YAC128 transgenic mice. Brain Res. Bull. 2012, 88:137-147.
    • (2012) Brain Res. Bull. , vol.88 , pp. 137-147
    • Bayram-Weston, Z.1    Jones, L.2    Dunnett, S.B.3    Brooks, S.P.4
  • 6
    • 84860841192 scopus 로고    scopus 로고
    • Light and electron microscopic characterization of the evolution of cellular pathology in the Hdh(Q92) Huntington's disease knock-in mice
    • Bayram-Weston Z., Jones L., Dunnett S.B., Brooks S.P. Light and electron microscopic characterization of the evolution of cellular pathology in the Hdh(Q92) Huntington's disease knock-in mice. Brain Res. Bull. 2012, 88:171-181.
    • (2012) Brain Res. Bull. , vol.88 , pp. 171-181
    • Bayram-Weston, Z.1    Jones, L.2    Dunnett, S.B.3    Brooks, S.P.4
  • 7
    • 84860841633 scopus 로고    scopus 로고
    • Light and electron microscopic characterisation of the evolution of cellular pathology in the Hdh(CAG(Q150)) Huntington's disease knock-in mouse
    • Bayram-Weston Z., Torres E.M., Jones L., Dunnett S.B., Brooks S.P. Light and electron microscopic characterisation of the evolution of cellular pathology in the Hdh(CAG(Q150)) Huntington's disease knock-in mouse. Brain Res. Bull. 2012, 88:182-188.
    • (2012) Brain Res. Bull. , vol.88 , pp. 182-188
    • Bayram-Weston, Z.1    Torres, E.M.2    Jones, L.3    Dunnett, S.B.4    Brooks, S.P.5
  • 8
    • 2342598416 scopus 로고    scopus 로고
    • Experimental therapeutics in transgenic mouse models of Huntington's disease
    • Beal M.F., Ferrante R.J. Experimental therapeutics in transgenic mouse models of Huntington's disease. Nat. Rev. Neurosci. 2004, 5:373-384.
    • (2004) Nat. Rev. Neurosci. , vol.5 , pp. 373-384
    • Beal, M.F.1    Ferrante, R.J.2
  • 9
    • 0034212645 scopus 로고    scopus 로고
    • Medial frontal cortex mediates perceptual attentional set shifting in the rat
    • Birrell J.M., Brown V.J. Medial frontal cortex mediates perceptual attentional set shifting in the rat. J. Neurosci. 2000, 20:4320-4324.
    • (2000) J. Neurosci. , vol.20 , pp. 4320-4324
    • Birrell, J.M.1    Brown, V.J.2
  • 11
    • 70349299834 scopus 로고    scopus 로고
    • Increased numbers of motor activity peaks during light cycle are associated with reductions in adrenergic alpha(2)-receptor levels in a transgenic Huntington's disease rat model
    • Bode F.J., Stephan M., Wiehager S., Nguyen H.P., Björkqvist M., von Hörsten S., Bauer A., Petersen A. Increased numbers of motor activity peaks during light cycle are associated with reductions in adrenergic alpha(2)-receptor levels in a transgenic Huntington's disease rat model. Behav. Brain Res. 2009, 205:175-182.
    • (2009) Behav. Brain Res. , vol.205 , pp. 175-182
    • Bode, F.J.1    Stephan, M.2    Wiehager, S.3    Nguyen, H.P.4    Björkqvist, M.5    von Hörsten, S.6    Bauer, A.7    Petersen, A.8
  • 13
    • 0345244817 scopus 로고    scopus 로고
    • Striatal lesions produce distinctive impairments in reaction time performance in two different operant chambers
    • Brasted P.J., Döbrössy M.D., Robbins T.W., Dunnett S.B. Striatal lesions produce distinctive impairments in reaction time performance in two different operant chambers. Brain Res. Bull. 1998, 46:487-494.
    • (1998) Brain Res. Bull. , vol.46 , pp. 487-494
    • Brasted, P.J.1    Döbrössy, M.D.2    Robbins, T.W.3    Dunnett, S.B.4
  • 14
    • 33646038884 scopus 로고    scopus 로고
    • Selective extra-dimensional set shifting deficit in a knock-in mouse model of Huntington's disease
    • Brooks S.P., Betteridge H., Trueman R.C., Jones L., Dunnett S.B. Selective extra-dimensional set shifting deficit in a knock-in mouse model of Huntington's disease. Brain Res. Bull. 2006, 69:452-457.
    • (2006) Brain Res. Bull. , vol.69 , pp. 452-457
    • Brooks, S.P.1    Betteridge, H.2    Trueman, R.C.3    Jones, L.4    Dunnett, S.B.5
  • 15
    • 84860837933 scopus 로고    scopus 로고
    • Longitudinal analysis of the behavioural phenotype in Hdh Q92 Huntington's disease knock-in mice
    • Brooks S.P., Higgs G.V., Jones L., Dunnett S.B. Longitudinal analysis of the behavioural phenotype in Hdh Q92 Huntington's disease knock-in mice. Brain Res. Bull. 2012, 88:148-155.
    • (2012) Brain Res. Bull. , vol.88 , pp. 148-155
    • Brooks, S.P.1    Higgs, G.V.2    Jones, L.3    Dunnett, S.B.4
  • 18
    • 84860837106 scopus 로고    scopus 로고
    • Longitudinal analysis of operant performance on the serial implicit learning task (SILT) in the YAC128 Huntington's disease mouse line
    • Brooks S.P., Jones L., Dunnett S.B. Longitudinal analysis of operant performance on the serial implicit learning task (SILT) in the YAC128 Huntington's disease mouse line. Brain Res. Bull. 2012, 88:130-136.
    • (2012) Brain Res. Bull. , vol.88 , pp. 130-136
    • Brooks, S.P.1    Jones, L.2    Dunnett, S.B.3
  • 19
    • 36448950196 scopus 로고    scopus 로고
    • Striatal lesions in the mouse disrupt acquisition and retention, but not implicit learning, in the SILT procedural motor learning task
    • Brooks S.P., Trueman R.C., Dunnett S.B. Striatal lesions in the mouse disrupt acquisition and retention, but not implicit learning, in the SILT procedural motor learning task. Brain Res. 2007, 1185:179-188.
    • (2007) Brain Res. , vol.1185 , pp. 179-188
    • Brooks, S.P.1    Trueman, R.C.2    Dunnett, S.B.3
  • 20
    • 67349224632 scopus 로고    scopus 로고
    • Subtle but progressive cognitive deficits in the female tgHD hemizygote rat as demonstrated by operant SILT performance
    • Brooks S.P., Fielding S., Döbrössy M.D., von Hörsten S., Dunnett S.B. Subtle but progressive cognitive deficits in the female tgHD hemizygote rat as demonstrated by operant SILT performance. Brain Res. Bull. 2009, 79:310-315.
    • (2009) Brain Res. Bull. , vol.79 , pp. 310-315
    • Brooks, S.P.1    Fielding, S.2    Döbrössy, M.D.3    von Hörsten, S.4    Dunnett, S.B.5
  • 21
    • 0026070312 scopus 로고
    • Response-related deficits following unilateral lesions of the medial agranular cortex of the rat
    • Brown V.J., Bowman E.M., Robbins T.W. Response-related deficits following unilateral lesions of the medial agranular cortex of the rat. Behav. Neurosci. 1991, 105:567-578.
    • (1991) Behav. Neurosci. , vol.105 , pp. 567-578
    • Brown, V.J.1    Bowman, E.M.2    Robbins, T.W.3
  • 22
    • 0024355953 scopus 로고
    • Elementary processes of response selection mediated by distinct regions of the striatum
    • Brown V.J., Robbins T.W. Elementary processes of response selection mediated by distinct regions of the striatum. J. Neurosci. 1989, 9:3760-3765.
    • (1989) J. Neurosci. , vol.9 , pp. 3760-3765
    • Brown, V.J.1    Robbins, T.W.2
  • 24
    • 0021995997 scopus 로고
    • Depletion of unilateral striatal dopamine impairs initiation of contralateral actions and not sensory attention
    • Carli M., Evenden J.L., Robbins T.W. Depletion of unilateral striatal dopamine impairs initiation of contralateral actions and not sensory attention. Nature 1985, 313:679-682.
    • (1985) Nature , vol.313 , pp. 679-682
    • Carli, M.1    Evenden, J.L.2    Robbins, T.W.3
  • 25
    • 0013060577 scopus 로고    scopus 로고
    • Neuropsychological and neuropsychiatric aspects of Huntington's disease
    • in: G.P. Bates, P.S. Harper, A.L. Jones (Eds.), Huntington's Disease, Oxford, New York
    • D. Craufurd, J.S. Snowden, Neuropsychological and neuropsychiatric aspects of Huntington's disease, in: G.P. Bates, P.S. Harper, A.L. Jones (Eds.), Huntington's Disease, Oxford, New York, 2002, pp. 62-94.
    • (2002) , pp. 62-94
    • Craufurd, D.1    Snowden, J.S.2
  • 27
    • 0017888218 scopus 로고
    • Behavioural and anatomical consequences of small intrastriatal injections of kainic acid in the rat
    • Divac I., Markowitsch H.J., Pritzel M. Behavioural and anatomical consequences of small intrastriatal injections of kainic acid in the rat. Brain Res. 1978, 151:523-532.
    • (1978) Brain Res. , vol.151 , pp. 523-532
    • Divac, I.1    Markowitsch, H.J.2    Pritzel, M.3
  • 29
    • 0020363241 scopus 로고
    • Neurotoxic lesions of ventrolateral but not anteromedial neostriatum in rats impair differential reinforcement of low rates (DRL) performance
    • Dunnett S.B., Iversen S.D. Neurotoxic lesions of ventrolateral but not anteromedial neostriatum in rats impair differential reinforcement of low rates (DRL) performance. Behav. Brain Res. 1982, 6:213-226.
    • (1982) Behav. Brain Res. , vol.6 , pp. 213-226
    • Dunnett, S.B.1    Iversen, S.D.2
  • 30
    • 26244445193 scopus 로고    scopus 로고
    • Frontal-striatal disconnection disrupts cognitive performance of the frontal-type in the rat
    • Dunnett S.B., Meldrum A., Muir J.L. Frontal-striatal disconnection disrupts cognitive performance of the frontal-type in the rat. Neuroscience 2005, 135:1055-1065.
    • (2005) Neuroscience , vol.135 , pp. 1055-1065
    • Dunnett, S.B.1    Meldrum, A.2    Muir, J.L.3
  • 32
    • 0032705528 scopus 로고    scopus 로고
    • Medial prefrontal and neostriatal lesions disrupt performance in an operant delayed alternation task in rats
    • Dunnett S.B., Nathwani F., Brasted P.J. Medial prefrontal and neostriatal lesions disrupt performance in an operant delayed alternation task in rats. Behav. Brain Res. 1999, 106:13-28.
    • (1999) Behav. Brain Res. , vol.106 , pp. 13-28
    • Dunnett, S.B.1    Nathwani, F.2    Brasted, P.J.3
  • 33
    • 0032888046 scopus 로고    scopus 로고
    • Effects of regional striatal lesions on motor, motivational and executive aspects of progressive ratio performance in rats
    • Eagle D.M., Humby T., Dunnett S.B., Robbins T.W. Effects of regional striatal lesions on motor, motivational and executive aspects of progressive ratio performance in rats. Behav. Neurosci. 1999, 113:718-731.
    • (1999) Behav. Neurosci. , vol.113 , pp. 718-731
    • Eagle, D.M.1    Humby, T.2    Dunnett, S.B.3    Robbins, T.W.4
  • 34
    • 0035211142 scopus 로고    scopus 로고
    • Perseverative behavior underlying attentional set-shifting deficits in rats chronically treated with the neurotoxin 3-nitropropionic acid
    • El Massioui N., Ouary S., Chéruel F., Hantraye P., Brouillet E. Perseverative behavior underlying attentional set-shifting deficits in rats chronically treated with the neurotoxin 3-nitropropionic acid. Exp. Neurol. 2001, 172:172-181.
    • (2001) Exp. Neurol. , vol.172 , pp. 172-181
    • El Massioui, N.1    Ouary, S.2    Chéruel, F.3    Hantraye, P.4    Brouillet, E.5
  • 36
    • 77949988313 scopus 로고    scopus 로고
    • Advances in the pharmacological management of Huntington's disease
    • Frank S., Jankovic J. Advances in the pharmacological management of Huntington's disease. Drugs 2010, 70:561-571.
    • (2010) Drugs , vol.70 , pp. 561-571
    • Frank, S.1    Jankovic, J.2
  • 37
    • 0038363448 scopus 로고    scopus 로고
    • The role of pretraining on skilled forelimb use in an animal model of Huntington's disease
    • Fricker-Gates R.A., Smith R.A., Muhith J., Dunnett S.B. The role of pretraining on skilled forelimb use in an animal model of Huntington's disease. Cell Transplant. 2003, 12:257-264.
    • (2003) Cell Transplant. , vol.12 , pp. 257-264
    • Fricker-Gates, R.A.1    Smith, R.A.2    Muhith, J.3    Dunnett, S.B.4
  • 38
    • 84873773231 scopus 로고
    • Effects of increment size and reinforcer volume on progressive ratio performance
    • Hodos W., Kalman G. Effects of increment size and reinforcer volume on progressive ratio performance. J. Exp. Anal. Behav. 1963, 6:387-392.
    • (1963) J. Exp. Anal. Behav. , vol.6 , pp. 387-392
    • Hodos, W.1    Kalman, G.2
  • 40
    • 0027480960 scopus 로고
    • A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes
    • Huntington's Disease Collaborative Research Group
    • Huntington's Disease Collaborative Research Group A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. Cell 1993, 72:971-983.
    • (1993) Cell , vol.72 , pp. 971-983
  • 41
    • 34249891319 scopus 로고    scopus 로고
    • An operant serial implicit learning task (SILT) in rats: task acquisition, performance and the effects of striatal lesions
    • Jay J.R., Dunnett S.B. An operant serial implicit learning task (SILT) in rats: task acquisition, performance and the effects of striatal lesions. J. Neurosci. Meth. 2007, 163:235-244.
    • (2007) J. Neurosci. Meth. , vol.163 , pp. 235-244
    • Jay, J.R.1    Dunnett, S.B.2
  • 43
    • 77950857170 scopus 로고    scopus 로고
    • Huntington's disease: pathogenesis to animal models
    • Kumar P., Kalonia H., Kumar A. Huntington's disease: pathogenesis to animal models. Pharmacol. Rep. 2010, 62:1-14.
    • (2010) Pharmacol. Rep. , vol.62 , pp. 1-14
    • Kumar, P.1    Kalonia, H.2    Kumar, A.3
  • 46
    • 0033934298 scopus 로고    scopus 로고
    • Visual object and visuospatial cognition in Huntington's disease: implications for information processing in corticostriatal circuits
    • Lawrence A.D., Watkins L.H.A., Sahakian B.J., Hodges J.R., Robbins T.W. Visual object and visuospatial cognition in Huntington's disease: implications for information processing in corticostriatal circuits. Brain 2000, 123:1349-1364.
    • (2000) Brain , vol.123 , pp. 1349-1364
    • Lawrence, A.D.1    Watkins, L.H.A.2    Sahakian, B.J.3    Hodges, J.R.4    Robbins, T.W.5
  • 48
    • 0034610505 scopus 로고    scopus 로고
    • Skilled reaching an action pattern: stability in rat (Rattus norvegicus) grasping movements as a function of changing food pellet size
    • Metz G.A., Whishaw I.Q. Skilled reaching an action pattern: stability in rat (Rattus norvegicus) grasping movements as a function of changing food pellet size. Behav. Brain Res. 2000, 116:111-122.
    • (2000) Behav. Brain Res. , vol.116 , pp. 111-122
    • Metz, G.A.1    Whishaw, I.Q.2
  • 49
    • 33750957672 scopus 로고    scopus 로고
    • Comparison of two different protocols of the rotarod test to assess motor deficit and lesion size in the 6-OHDA model
    • Monville C., Torres E.M., Dunnett S.B. Comparison of two different protocols of the rotarod test to assess motor deficit and lesion size in the 6-OHDA model. J. Neurosci. Meth. 2006, 158:219-223.
    • (2006) J. Neurosci. Meth. , vol.158 , pp. 219-223
    • Monville, C.1    Torres, E.M.2    Dunnett, S.B.3
  • 50
    • 0034958203 scopus 로고    scopus 로고
    • Progressive formation of inclusions in the brains of mice transgenic for the human Huntington's disease mutation parallels neurological decline
    • Morton A.J., Lagan M., Skepper J.N., Dunnett S.B. Progressive formation of inclusions in the brains of mice transgenic for the human Huntington's disease mutation parallels neurological decline. J. Neurocytol. 2000, 29:679-702.
    • (2000) J. Neurocytol. , vol.29 , pp. 679-702
    • Morton, A.J.1    Lagan, M.2    Skepper, J.N.3    Dunnett, S.B.4
  • 52
    • 0019600984 scopus 로고
    • Differential effects of prefrontal cortex ablation in neonatal, juvenile, and young adult rats
    • Nonneman A.J., Corwin J.V. Differential effects of prefrontal cortex ablation in neonatal, juvenile, and young adult rats. J. Comp. Physiol. Psychol. 1981, 95:588-602.
    • (1981) J. Comp. Physiol. Psychol. , vol.95 , pp. 588-602
    • Nonneman, A.J.1    Corwin, J.V.2
  • 53
    • 0002438047 scopus 로고
    • Methods of assessing attention and stimulus control in the rat, in: A. Sahgal (Ed.), Behavioural Neuroscience: A Practical Approach, Oxford
    • T.W. Robbins, J.L. Muir, A.S. Killcross, D. Pretsell, Methods of assessing attention and stimulus control in the rat, in: A. Sahgal (Ed.), Behavioural Neuroscience: A Practical Approach, vol. I, Oxford, 1993, pp. 13-47.
    • (1993) , vol.1 , pp. 13-47
    • Robbins, T.W.1    Muir, J.L.2    Killcross, A.S.3    Pretsell, D.4
  • 55
    • 0018612870 scopus 로고
    • Body weight, feeding and drinking behaviors in rats with kainic acid lesions of striatal neurons: with a note on body weight symptomatology in Huntington's disease
    • Sanberg P.R., Fibiger H.C. Body weight, feeding and drinking behaviors in rats with kainic acid lesions of striatal neurons: with a note on body weight symptomatology in Huntington's disease. Exp. Neurol. 1978, 66:444-466.
    • (1978) Exp. Neurol. , vol.66 , pp. 444-466
    • Sanberg, P.R.1    Fibiger, H.C.2
  • 59
    • 16244411642 scopus 로고    scopus 로고
    • Implicit learning in a serial choice visual discrimination task in the operant 9-hole box by intact and striatal lesioned mice
    • Trueman R.C., Brooks S.P., Dunnett S.B. Implicit learning in a serial choice visual discrimination task in the operant 9-hole box by intact and striatal lesioned mice. Behav. Brain Res. 2005, 159:313-322.
    • (2005) Behav. Brain Res. , vol.159 , pp. 313-322
    • Trueman, R.C.1    Brooks, S.P.2    Dunnett, S.B.3
  • 60
    • 33847053686 scopus 로고    scopus 로고
    • The operant serial implicit learning task reveals early-onset motor learning deficits in a knock-in mouse model of Huntington's disease
    • Trueman R.C., Brooks S.P., Jones L., Dunnett S.B. The operant serial implicit learning task reveals early-onset motor learning deficits in a knock-in mouse model of Huntington's disease. Eur. J. Neurosci. 2007, 25:551-558.
    • (2007) Eur. J. Neurosci. , vol.25 , pp. 551-558
    • Trueman, R.C.1    Brooks, S.P.2    Jones, L.3    Dunnett, S.B.4
  • 61
    • 41149153221 scopus 로고    scopus 로고
    • Q92/Q92 knock-in mouse model of Huntington's disease in the operant serial implicit learning task (SILT)
    • Q92/Q92 knock-in mouse model of Huntington's disease in the operant serial implicit learning task (SILT). Behav. Brain Res. 2008, 189:317-324.
    • (2008) Behav. Brain Res. , vol.189 , pp. 317-324
    • Trueman, R.C.1    Brooks, S.P.2    Jones, L.3    Dunnett, S.B.4
  • 63
    • 0035503912 scopus 로고    scopus 로고
    • Anterior cingulate cortical transplantation in transgenic Huntington's disease mice
    • van Dellen A., Deacon R., York D., Blakemore C., Hannan A.J. Anterior cingulate cortical transplantation in transgenic Huntington's disease mice. Brain Res. Bull. 2001, 56:313-318.
    • (2001) Brain Res. Bull. , vol.56 , pp. 313-318
    • van Dellen, A.1    Deacon, R.2    York, D.3    Blakemore, C.4    Hannan, A.J.5
  • 67
    • 33846225133 scopus 로고    scopus 로고
    • Huntington's disease
    • Walker F.O. Huntington's disease. Lancet 2007, 369:218-228.
    • (2007) Lancet , vol.369 , pp. 218-228
    • Walker, F.O.1
  • 68
    • 0025201875 scopus 로고
    • The structure of skilled forelimb reaching in the rat: a proximally driven movement with a single distal rotatory component
    • Whishaw I.Q., Pellis S.M. The structure of skilled forelimb reaching in the rat: a proximally driven movement with a single distal rotatory component. Behav. Brain Res. 1990, 41:49-59.
    • (1990) Behav. Brain Res. , vol.41 , pp. 49-59
    • Whishaw, I.Q.1    Pellis, S.M.2


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