메뉴 건너뛰기




Volumn 109, Issue 18, 2012, Pages

Murine gammaherpesvirus 68 infection protects lupus-prone mice from the development of autoimmunity

Author keywords

Antibody; Mouse gammaherpesvirus

Indexed keywords

AUTOANTIBODY; DOUBLE STRANDED DNA ANTIBODY;

EID: 84860821139     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1203019109     Document Type: Article
Times cited : (32)

References (76)
  • 1
    • 33746923499 scopus 로고    scopus 로고
    • Epstein-Barr virus and systemic lupus erythematosus
    • DOI 10.1097/01.bor.0000240355.37927.94, PII 0000228120060900000005
    • James JA, Harley JB, Scofield RH (2006) Epstein-Barr virus and systemic lupus erythematosus. Curr Opin Rheumatol 18:462-467. (Pubitemid 44200328)
    • (2006) Current Opinion in Rheumatology , vol.18 , Issue.5 , pp. 462-467
    • James, J.A.1    Harley, J.B.2    Scofield, R.H.3
  • 2
    • 15944410612 scopus 로고    scopus 로고
    • Amplification of autoimmune disease by infection
    • DOI 10.1186/ar1691
    • Posnett DN, Yarilin D (2005) Amplification of autoimmune disease by infection. Arthritis Res Ther 7:74-84. (Pubitemid 40439442)
    • (2005) Arthritis Research and Therapy , vol.7 , Issue.2 , pp. 74-84
    • Posnett, D.N.1    Yarilin, D.2
  • 4
    • 77958146282 scopus 로고    scopus 로고
    • Latent membrane protein 1, the EBV-encoded oncogenic mimic of CD40, accelerates autoimmunity in B6.Sle1 mice
    • Peters AL, Stunz LL, Meyerholz DK, Mohan C, Bishop GA (2010) Latent membrane protein 1, the EBV-encoded oncogenic mimic of CD40, accelerates autoimmunity in B6.Sle1 mice. J Immunol 185:4053-4062.
    • (2010) J Immunol , vol.185 , pp. 4053-4062
    • Peters, A.L.1    Stunz, L.L.2    Meyerholz, D.K.3    Mohan, C.4    Bishop, G.A.5
  • 5
    • 19944382176 scopus 로고    scopus 로고
    • Epstein-Barr virus LMP2A alters in vivo and in vitro models of B-cell anergy, but not deletion, in response to autoantigen
    • DOI 10.1128/JVI.79.12.7355-7362.2005
    • Swanson-Mungerson MA, Caldwell RG, Bultema R, Longnecker R (2005) Epstein-Barr virus LMP2A alters in vivo and in vitro models of B-cell anergy, but not deletion, in response to autoantigen. J Virol 79:7355-7362. (Pubitemid 40756771)
    • (2005) Journal of Virology , vol.79 , Issue.12 , pp. 7355-7362
    • Swanson-Mungerson, M.A.1    Caldwell, R.G.2    Bultema, R.3    Longnecker, R.4
  • 7
    • 0033674936 scopus 로고    scopus 로고
    • Murine gamma-herpesvirus- 68: A mouse model for infectious mononucleosis?
    • Blackman MA, Flaño E, Usherwood E, Woodland DL (2000) Murine gamma-herpesvirus- 68: A mouse model for infectious mononucleosis? Mol Med Today 6:488-490.
    • (2000) Mol Med Today , vol.6 , pp. 488-490
    • Blackman, M.A.1    Flaño, E.2    Usherwood, E.3    Woodland, D.L.4
  • 8
    • 0033178351 scopus 로고    scopus 로고
    • Unraveling immunity to gamma-herpesviruses: A new model for understanding the role of immunity in chronic virus infection
    • Virgin HW, Speck SH (1999) Unraveling immunity to gamma-herpesviruses: A new model for understanding the role of immunity in chronic virus infection. Curr Opin Immunol 11:371-379.
    • (1999) Curr Opin Immunol , vol.11 , pp. 371-379
    • Virgin, H.W.1    Speck, S.H.2
  • 9
    • 79953048485 scopus 로고    scopus 로고
    • Pathogenesis and host control of gammaherpesviruses: Lessons from the mouse
    • Barton E, Mandal P, Speck SH (2011) Pathogenesis and host control of gammaherpesviruses: Lessons from the mouse. Annu Rev Immunol 29:351-397.
    • (2011) Annu Rev Immunol , vol.29 , pp. 351-397
    • Barton, E.1    Mandal, P.2    Speck, S.H.3
  • 11
    • 0031907464 scopus 로고    scopus 로고
    • Kinetic analysis of the specific host response to a murine gammaherpesvirus
    • Stevenson PG, Doherty PC (1998) Kinetic analysis of the specific host response to a murine gammaherpesvirus. J Virol 72:943-949. (Pubitemid 28116871)
    • (1998) Journal of Virology , vol.72 , Issue.2 , pp. 943-949
    • Stevenson, P.G.1    Doherty, P.C.2
  • 13
    • 0036241226 scopus 로고    scopus 로고
    • A mouse model for infectious mononucleosis
    • DOI 10.1385/IR:25:3:201
    • Flaño E, Woodland DL, Blackman MA (2002a) A mouse model for infectious mononucleosis. Immunol Res 25:201-217. (Pubitemid 34454712)
    • (2002) Immunologic Research , vol.25 , Issue.3 , pp. 201-217
    • Flano, E.1    Woodland, D.L.2    Blackman, M.A.3
  • 15
    • 0027179405 scopus 로고
    • Pathogenesis of murine gammaherpesvirus infection in mice deficient in CD4 and CD8 T cells
    • Ehtisham S, Sunil-Chandra NP, NashAA (1993) Pathogenesis ofmurine gammaherpesvirus infection in mice deficient in CD4 and CD8 T cells. J Virol 67:5247-5252. (Pubitemid 23241355)
    • (1993) Journal of Virology , vol.67 , Issue.9 , pp. 5247-5252
    • Ehtisham, S.1    Sunil-Chandra, N.P.2    Nash, A.A.3
  • 16
    • 0032526299 scopus 로고    scopus 로고
    • Lung epithelial cells are a major site of murine gammaherpesvirus persistence
    • DOI 10.1084/jem.187.12.1941
    • Stewart JP, Usherwood EJ, Ross A, Dyson H, Nash T (1998) Lung epithelial cells are a major site of murine gammaherpesvirus persistence. J Exp Med 187:1941-1951. (Pubitemid 28285564)
    • (1998) Journal of Experimental Medicine , vol.187 , Issue.12 , pp. 1941-1951
    • Stewart, J.P.1    Usherwood, E.J.2    Ross, A.3    Dyson, H.4    Nash, T.5
  • 18
    • 0032975256 scopus 로고    scopus 로고
    • Macrophages are the major reservoir of latent murine gammaherpesvirus 68 in peritoneal cells
    • Weck KE, Kim SS, Virgin HW IV, Speck SH (1999a) Macrophages are the major reservoir of latent murine gammaherpesvirus 68 in peritoneal cells. J Virol 73: 3273-3283. (Pubitemid 29135720)
    • (1999) Journal of Virology , vol.73 , Issue.4 , pp. 3273-3283
    • Weck, K.E.1    Kim, S.S.2    Virgin IV, H.W.3    Speck, S.H.4
  • 19
    • 0037131972 scopus 로고    scopus 로고
    • Gamma-Herpesvirus latency is preferentially maintained in splenic germinal center and memory B cells
    • DOI 10.1084/jem.20020890
    • Flaño E, Kim IJ, Woodland DL, Blackman MA (2002b) Gamma-herpesvirus latency is preferentially maintained in splenic germinal center and memory B cells. J Exp Med 196:1363-1372. (Pubitemid 35375555)
    • (2002) Journal of Experimental Medicine , vol.196 , Issue.10 , pp. 1363-1372
    • Flano, E.1    Kim, I.-J.2    Woodland, D.L.3    Blackman, M.A.4
  • 20
    • 23844518957 scopus 로고    scopus 로고
    • Infection of dendritic cells by a gamma2-herpesvirus induces functional modulation
    • Flaño E, Kayhan B, Woodland DL, Blackman MA (2005) Infection of dendritic cells by a gamma2-herpesvirus induces functional modulation. J Immunol 175:3225-3234. (Pubitemid 41170543)
    • (2005) Journal of Immunology , vol.175 , Issue.5 , pp. 3225-3234
    • Flano, E.1    Kayhan, B.2    Woodland, D.L.3    Blackman, M.A.4
  • 21
    • 34347355579 scopus 로고    scopus 로고
    • Murine gammaherpesvirus-68 productively infects immature dendritic cells and blocks maturation
    • DOI 10.1099/vir.0.82931-0
    • Hochreiter R, Ptaschinski C, Kunkel SL, Rochford R (2007) Murine gammaherpesvirus- 68 productively infects immature dendritic cells and blocks maturation. J Gen Virol 88: 1896-1905. (Pubitemid 47009930)
    • (2007) Journal of General Virology , vol.88 , Issue.7 , pp. 1896-1905
    • Hochreiter, R.1    Ptaschinski, C.2    Kunkel, S.L.3    Rochford, R.4
  • 22
    • 0029811734 scopus 로고    scopus 로고
    • Progressive loss of CD8+ T cell-mediated control of a gamma-herpesvirus in the absence of CD4+ T cells
    • Cardin RD, Brooks JW, Sarawar SR, Doherty PC (1996) Progressive loss of CD8+ T cell-mediated control of a gamma-herpesvirus in the absence of CD4+ T cells. J Exp Med 184:863-871.
    • (1996) J Exp Med , vol.184 , pp. 863-871
    • Cardin, R.D.1    Brooks, J.W.2    Sarawar, S.R.3    Doherty, P.C.4
  • 24
    • 2942693575 scopus 로고    scopus 로고
    • An optimized CD4 T-cell response can control productive and latent gammaherpesvirus infection
    • DOI 10.1128/JVI.78.13.6827-6835.2004
    • Sparks-Thissen RL, Braaten DC, Kreher S, Speck SH, Virgin HW, 4th (2004) An optimized CD4 T-cell response can control productive and latent gammaherpesvirus infection. J Virol 78:6827-6835. (Pubitemid 38781520)
    • (2004) Journal of Virology , vol.78 , Issue.13 , pp. 6827-6835
    • Sparks-Thissen, R.L.1    Braaten, D.C.2    Kreher, S.3    Speck, S.H.4    Virgin IV, H.W.5
  • 25
    • 13444273347 scopus 로고    scopus 로고
    • + T-cell response controls productive and latent gammaherpesvirus infection
    • DOI 10.1128/JVI.79.4.2573-2583.2005
    • Braaten DC, Sparks-Thissen RL, Kreher S, Speck SH, Virgin HW, 4th (2005) An optimized CD8+ T-cell response controls productive and latent gammaherpesvirus infection. J Virol 79:2573-2583. (Pubitemid 40204611)
    • (2005) Journal of Virology , vol.79 , Issue.4 , pp. 2573-2583
    • Braaten, D.C.1    Sparks-Thissen, R.L.2    Kreher, S.3    Speck, S.H.4    Virgin IV, H.W.5
  • 26
    • 22544471814 scopus 로고    scopus 로고
    • CD4 T cell control of acute and latent murine gammaherpesvirus infection requires IFNgamma
    • DOI 10.1016/j.virol.2005.05.011, PII S0042682205002965
    • Sparks-Thissen RL, et al. (2005) CD4 T cell control of acute and latent murine gammaherpesvirus infection requires IFNgamma. Virology 338:201-208. (Pubitemid 41019189)
    • (2005) Virology , vol.338 , Issue.2 , pp. 201-208
    • Sparks-Thissen, R.L.1    Braaten, D.C.2    Hildner, K.3    Murphy, T.L.4    Murphy, K.M.5    Virgin IV, H.W.6
  • 27
    • 27644558111 scopus 로고    scopus 로고
    • Alpha/beta interferons regulate murine gammaherpesvirus latent gene expression and reactivation from latency
    • DOI 10.1128/JVI.79.22.14149-14160.2005
    • Barton ES, Lutzke ML, Rochford R, Virgin HW, 4th (2005) Alpha/beta interferons regulate murine gammaherpesvirus latent gene expression and reactivation from latency. J Virol 79:14149-14160. (Pubitemid 41552713)
    • (2005) Journal of Virology , vol.79 , Issue.22 , pp. 14149-14160
    • Barton, E.S.1    Lutzke, M.L.2    Rochford, R.3    Virgin IV, H.W.4
  • 28
    • 59749098438 scopus 로고    scopus 로고
    • Signaling through Toll-like receptors induces murine gammaherpesvirus 68 reactivation in vivo
    • Gargano LM, Forrest JC, Speck SH (2009) Signaling through Toll-like receptors induces murine gammaherpesvirus 68 reactivation in vivo. J Virol 83:1474-1482.
    • (2009) J Virol , vol.83 , pp. 1474-1482
    • Gargano, L.M.1    Forrest, J.C.2    Speck, S.H.3
  • 29
    • 38849130083 scopus 로고    scopus 로고
    • Murine gammaherpesvirus-68 infection alters self-antigen presentation and type 1 diabetes onset in NOD mice
    • Smith KA, Efstathiou S, Cooke A (2007) Murine gammaherpesvirus-68 infection alters self-antigen presentation and type 1 diabetes onset in NOD mice. J Immunol 179: 7325-7333.
    • (2007) J Immunol , vol.179 , pp. 7325-7333
    • Smith, K.A.1    Efstathiou, S.2    Cooke, A.3
  • 30
    • 6344250541 scopus 로고    scopus 로고
    • A mouse herpesvirus induces relapse of experimental autoimmune arthritis by infection of the inflammatory target tissue
    • Yarilin DA, Valiando J, Posnett DN (2004) A mouse herpesvirus induces relapse of experimental autoimmune arthritis by infection of the inflammatory target tissue. J Immunol 173:5238-5246. (Pubitemid 39387807)
    • (2004) Journal of Immunology , vol.173 , Issue.8 , pp. 5238-5246
    • Yarilin, D.A.1    Valiando, J.2    Posnett, D.N.3
  • 31
    • 0042469389 scopus 로고    scopus 로고
    • Exacerbation of experimental autoimmune encephalomyelitis in rodents infected with murine gammaherpesvirus-68
    • DOI 10.1002/eji.200323148
    • Peacock JW, Elsawa SF, Petty CC, Hickey WF, Bost KL (2003) Exacerbation of experimental autoimmune encephalomyelitis in rodents infected with murine gammaherpesvirus-68. Eur J Immunol 33:1849-1858. (Pubitemid 37120856)
    • (2003) European Journal of Immunology , vol.33 , Issue.7 , pp. 1849-1858
    • Peacock, J.W.1    Elsawa, S.F.2    Petty, C.C.3    Hickey, W.F.4    Bost, K.L.5
  • 32
    • 0033179090 scopus 로고    scopus 로고
    • Host and viral genetics of chronic infection: A mouse model of gamma- herpesvirus pathogenesis
    • DOI 10.1016/S1369-5274(99)80071-X
    • Speck SH, Virgin HW (1999) Host and viral genetics of chronic infection: A mouse model of gamma-herpesvirus pathogenesis. Curr Opin Microbiol 2:403-409. (Pubitemid 29366963)
    • (1999) Current Opinion in Microbiology , vol.2 , Issue.4 , pp. 403-409
    • Speck, S.H.1    Virgin IV, H.W.2
  • 33
    • 33644658410 scopus 로고    scopus 로고
    • Receptor editing for better or for worse
    • DOI 10.1016/j.coi.2006.01.005, PII S0952791506000070, Lymphocyte Development / Tumor Immunology
    • Pelanda R, Torres RM (2006) Receptor editing for better or for worse. Curr Opin Immunol 18:184-190. (Pubitemid 43327300)
    • (2006) Current Opinion in Immunology , vol.18 , Issue.2 , pp. 184-190
    • Pelanda, R.1    Torres, R.M.2
  • 34
    • 34447098797 scopus 로고    scopus 로고
    • Multistep pathogenesis of autoimmune disease
    • Goodnow CC (2007) Multistep pathogenesis of autoimmune disease. Cell 130:25-35.
    • (2007) Cell , vol.130 , pp. 25-35
    • Goodnow, C.C.1
  • 35
    • 37849035658 scopus 로고    scopus 로고
    • Sites and stages of autoreactive B cell activation and regulation
    • Shlomchik MJ (2008) Sites and stages of autoreactive B cell activation and regulation. Immunity 28:18-28.
    • (2008) Immunity , vol.28 , pp. 18-28
    • Shlomchik, M.J.1
  • 37
    • 34247574562 scopus 로고    scopus 로고
    • Susceptibility genes in the pathogenesis of murine lupus
    • Nguyen C, Limaye N, Wakeland EK (2002) Susceptibility genes in the pathogenesis of murine lupus. Arthritis Res 4(suppl 3):S255-S263.
    • (2002) Arthritis Res , vol.4 , Issue.SUPPL. 3
    • Nguyen, C.1    Limaye, N.2    Wakeland, E.K.3
  • 38
    • 34447099218 scopus 로고    scopus 로고
    • Systemic Lupus Erythematosus: Multiple Immunological Phenotypes in a Complex Genetic Disease
    • DOI 10.1016/S0065-2776(06)92001-X, PII S006527760692001X
    • Fairhurst AM, Wandstrat AE, Wakeland EK (2006) Systemic lupus erythematosus: Multiple immunological phenotypes in a complex genetic disease. Adv Immunol 92: 1-69. (Pubitemid 44828118)
    • (2006) Advances in Immunology , vol.92 , pp. 1-69
    • Fairhurst, A.1    Wandstrat, A.E.2    Wakeland, E.K.3
  • 39
    • 84855431164 scopus 로고    scopus 로고
    • Genetics of systemic lupus erythematosus: Contributions of mouse models in the era of human genome-wide association studies
    • Xu Z, Morel L (2010) Genetics of systemic lupus erythematosus: Contributions of mouse models in the era of human genome-wide association studies. Discov Med 10: 71-78.
    • (2010) Discov Med , vol.10 , pp. 71-78
    • Xu, Z.1    Morel, L.2
  • 41
    • 0037405936 scopus 로고    scopus 로고
    • Maintenance of gammaherpesvirus latency requires viral cyclin in the absence of B lymphocytes
    • van Dyk LF, Virgin HW, 4th, Speck SH (2003) Maintenance of gammaherpesvirus latency requires viral cyclin in the absence of B lymphocytes. J Virol 77:5118-5126.
    • (2003) J Virol , vol.77 , pp. 5118-5126
    • Van Dyk, L.F.1    Virgin IV, H.W.2    Speck, S.H.3
  • 42
    • 70349736116 scopus 로고    scopus 로고
    • Cross-regulation of signaling pathways by interferon-gamma: Implications for immune responses and autoimmune diseases
    • Hu X, Ivashkiv LB (2009) Cross-regulation of signaling pathways by interferon-gamma: Implications for immune responses and autoimmune diseases. Immunity 31:539-550.
    • (2009) Immunity , vol.31 , pp. 539-550
    • Hu, X.1    Ivashkiv, L.B.2
  • 44
    • 0036721775 scopus 로고    scopus 로고
    • The major murine systemic lupus erythematosus susceptibility locus Sle1 results in abnormal functions of both B and T cells
    • Sobel ES, Satoh M, Chen Y, Wakeland EK, Morel L (2002) The major murine systemic lupus erythematosus susceptibility locus Sle1 results in abnormal functions of both B and T cells. J Immunol 169:2694-2700. (Pubitemid 34921018)
    • (2002) Journal of Immunology , vol.169 , Issue.5 , pp. 2694-2700
    • Sobel, E.S.1    Satoh, M.2    Chen, Y.3    Wakeland, E.K.4    Morel, L.5
  • 45
    • 80051568169 scopus 로고    scopus 로고
    • + B-cell population is important for the development of autoimmunity
    • + B-cell population is important for the development of autoimmunity. Blood 118:1305-1315.
    • (2011) Blood , vol.118 , pp. 1305-1315
    • Rubtsov, A.V.1
  • 46
    • 80051569441 scopus 로고    scopus 로고
    • A B-cell subset uniquely responsive to innate stimuli accumulates in aged mice
    • Hao Y, O'Neill PJ, Naradikian MS, Scholz JL, Cancro MP (2011) A B-cell subset uniquely responsive to innate stimuli accumulates in aged mice. Blood 118:1294-1304.
    • (2011) Blood , vol.118 , pp. 1294-1304
    • Hao, Y.1    O'Neill, P.J.2    Naradikian, M.S.3    Scholz, J.L.4    Cancro, M.P.5
  • 49
    • 0014419858 scopus 로고
    • Antinuclear antibodies in infectious mononucleosis
    • Kaplan ME, Tan EM (1968) Antinuclear antibodies in infectious mononucleosis. Lancet 1:561-563.
    • (1968) Lancet , vol.1 , pp. 561-563
    • Kaplan, M.E.1    Tan, E.M.2
  • 53
    • 0030979780 scopus 로고    scopus 로고
    • Pathological changes in the spleens of gamma interferon receptor- deficient mice infected with murine gammaherpesvirus: A role for CD8 T cells
    • Dutia BM, Clarke CJ, Allen DJ, Nash AA (1997) Pathological changes in the spleens of gamma interferon receptor-deficient mice infected with murine gammaherpesvirus: a role for CD8 T cells. J Virol 71:4278-4283. (Pubitemid 27204114)
    • (1997) Journal of Virology , vol.71 , Issue.6 , pp. 4278-4283
    • Dutia, B.M.1    Clarke, C.J.2    Allen, D.J.3    Nash, A.A.4
  • 54
    • 33748472865 scopus 로고    scopus 로고
    • Toll-like Receptor 7 and TLR9 Dictate Autoantibody Specificity and Have Opposing Inflammatory and Regulatory Roles in a Murine Model of Lupus
    • DOI 10.1016/j.immuni.2006.07.013, PII S1074761306003906
    • Christensen SR, et al. (2006) Toll-like receptor 7 and TLR9 dictate autoantibody specificity and have opposing inflammatory and regulatory roles in a murine model of lupus. Immunity 25:417-428. (Pubitemid 44354217)
    • (2006) Immunity , vol.25 , Issue.3 , pp. 417-428
    • Christensen, S.R.1    Shupe, J.2    Nickerson, K.3    Kashgarian, M.4    Flavell, R.A.5    Shlomchik, M.J.6
  • 56
    • 36048962438 scopus 로고    scopus 로고
    • Control of Toll-like Receptor 7 Expression Is Essential to Restrict Autoimmunity and Dendritic Cell Proliferation
    • DOI 10.1016/j.immuni.2007.09.009, PII S1074761307004906
    • Deane JA, et al. (2007) Control of toll-like receptor 7 expression is essential to restrict autoimmunity and dendritic cell proliferation. Immunity 27:801-810. (Pubitemid 350102256)
    • (2007) Immunity , vol.27 , Issue.5 , pp. 801-810
    • Deane, J.A.1    Pisitkun, P.2    Barrett, R.S.3    Feigenbaum, L.4    Town, T.5    Ward, J.M.6    Flavell, R.A.7    Bolland, S.8
  • 57
    • 77949903821 scopus 로고    scopus 로고
    • TLR9 regulates TLR7- And MyD88-dependent auto-antibody production and disease in a murine model of lupus
    • Nickerson KM, et al. (2010) TLR9 regulates TLR7- and MyD88-dependent auto-antibody production and disease in a murine model of lupus. J Immunol 184:1840-1848.
    • (2010) J Immunol , vol.184 , pp. 1840-1848
    • Nickerson, K.M.1
  • 58
    • 79251567968 scopus 로고    scopus 로고
    • EBV lytic-phase protein BGLF5 contributes to TLR9 downregulation during productive infection
    • van Gent M, et al. (2011) EBV lytic-phase protein BGLF5 contributes to TLR9 downregulation during productive infection. J Immunol 186:1694-1702.
    • (2011) J Immunol , vol.186 , pp. 1694-1702
    • Van Gent, M.1
  • 59
    • 68149163563 scopus 로고    scopus 로고
    • A bridge crosses the active-site canyon of the Epstein-Barr virus nuclease with DNase and RNase activities
    • Buisson M, et al. (2009) A bridge crosses the active-site canyon of the Epstein-Barr virus nuclease with DNase and RNase activities. J Mol Biol 391:717-728.
    • (2009) J Mol Biol , vol.391 , pp. 717-728
    • Buisson, M.1
  • 60
    • 69449095602 scopus 로고    scopus 로고
    • Host shutoff is a conserved phenotype of gammaherpesvirus infection and is orchestrated exclusively from the cytoplasm
    • Covarrubias S, Richner JM, Clyde K, Lee YJ, Glaunsinger BA (2009) Host shutoff is a conserved phenotype of gammaherpesvirus infection and is orchestrated exclusively from the cytoplasm. J Virol 83:9554-9566.
    • (2009) J Virol , vol.83 , pp. 9554-9566
    • Covarrubias, S.1    Richner, J.M.2    Clyde, K.3    Lee, Y.J.4    Glaunsinger, B.A.5
  • 61
    • 40449107086 scopus 로고    scopus 로고
    • TLR9 contributes to antiviral immunity during gammaherpesvirus infection
    • Guggemoos S, et al. (2008) TLR9 contributes to antiviral immunity during gammaherpesvirus infection. J Immunol 180:438-443.
    • (2008) J Immunol , vol.180 , pp. 438-443
    • Guggemoos, S.1
  • 62
    • 77952242576 scopus 로고    scopus 로고
    • Critical role of TLR7 in the acceleration of systemic lupus erythematosus in TLR9-deficient mice
    • Santiago-Raber ML, et al. (2010) Critical role of TLR7 in the acceleration of systemic lupus erythematosus in TLR9-deficient mice. J Autoimmun 34:339-348.
    • (2010) J Autoimmun , vol.34 , pp. 339-348
    • Santiago-Raber, M.L.1
  • 63
    • 0034662270 scopus 로고    scopus 로고
    • Latent murine gamma-herpesvirus infection is established in activated B cells, dendritic cells, and macrophages
    • Flaño E, Husain SM, Sample JT, Woodland DL, Blackman MA (2000) Latent murine gamma-herpesvirus infection is established in activated B cells, dendritic cells, and macrophages. J Immunol 165:1074-1081. (Pubitemid 30484779)
    • (2000) Journal of Immunology , vol.165 , Issue.2 , pp. 1074-1081
    • Flano, E.1    Husain, S.M.2    Sample, J.T.3    Woodland, D.L.4    Blackman, M.A.5
  • 64
    • 67650472427 scopus 로고    scopus 로고
    • Molecular hallmarks of anti-chromatin antibodies associated with the lupus susceptibility locus, Sle1
    • Liang Z, Chang S, Youn MS, Mohan C (2009) Molecular hallmarks of anti-chromatin antibodies associated with the lupus susceptibility locus, Sle1. Mol Immunol 46: 2671-2681.
    • (2009) Mol Immunol , vol.46 , pp. 2671-2681
    • Liang, Z.1    Chang, S.2    Youn, M.S.3    Mohan, C.4
  • 65
    • 1642355724 scopus 로고    scopus 로고
    • Viral degradation of the MHC class I peptide loading complex
    • DOI 10.1016/S1074-7613(04)00047-0, PII S1074761304000470
    • Boname JM, de Lima BD, Lehner PJ, Stevenson PG (2004) Viral degradation of the MHC class I peptide loading complex. Immunity 20:305-317. (Pubitemid 38388232)
    • (2004) Immunity , vol.20 , Issue.3 , pp. 305-317
    • Boname, J.M.1    De Lima, B.D.2    Lehner, P.J.3    Stevenson, P.G.4
  • 66
    • 45749086951 scopus 로고    scopus 로고
    • The Gammaherpesvirus m2 protein manipulates the Fyn/Vav pathway through a multidocking mechanism of assembly
    • Pires de Miranda M, et al. (2008) The Gammaherpesvirus m2 protein manipulates the Fyn/Vav pathway through a multidocking mechanism of assembly. PLoS One 3: e1654.
    • (2008) PLoS One , vol.3
    • Pires De Miranda, M.1
  • 67
    • 65649128907 scopus 로고    scopus 로고
    • Termination of NF-kappaB activity through a gammaherpesvirus protein that assembles an EC5S ubiquitin-ligase
    • Rodrigues L, et al. (2009) Termination of NF-kappaB activity through a gammaherpesvirus protein that assembles an EC5S ubiquitin-ligase. EMBO J 28: 1283-1295.
    • (2009) EMBO J , vol.28 , pp. 1283-1295
    • Rodrigues, L.1
  • 69
    • 33845948381 scopus 로고    scopus 로고
    • + T cell regulatory functions
    • Wan S, Xia C, Morel L (2007) IL-6 produced by dendritic cells from lupus-prone mice inhibits CD4+CD25+ T cell regulatory functions. J Immunol 178:271-279. (Pubitemid 46033610)
    • (2007) Journal of Immunology , vol.178 , Issue.1 , pp. 271-279
    • Wan, S.1    Xia, C.2    Morel, L.3
  • 70
    • 45349090413 scopus 로고    scopus 로고
    • Direct B cell stimulation by dendritic cells in a mouse model of lupus
    • DOI 10.1002/art.23515
    • Wan S, Zhou Z, Duan B, Morel L (2008) Direct B cell stimulation by dendritic cells in a mouse model of lupus. Arthritis Rheum 58:1741-1750. (Pubitemid 351847528)
    • (2008) Arthritis and Rheumatism , vol.58 , Issue.6 , pp. 1741-1750
    • Wan, S.1    Zhou, Z.2    Duan, B.3    Morel, L.4
  • 71
  • 72
    • 67649660551 scopus 로고    scopus 로고
    • Redefining chronic viral infection
    • Virgin HW, Wherry EJ, Ahmed R (2009) Redefining chronic viral infection. Cell 138: 30-50.
    • (2009) Cell , vol.138 , pp. 30-50
    • Virgin, H.W.1    Wherry, E.J.2    Ahmed, R.3
  • 73
    • 4344633188 scopus 로고    scopus 로고
    • Update on human systemic lupus erythematosus genetics
    • Tsao BP (2004) Update on human systemic lupus erythematosus genetics. Curr Opin Rheumatol 16:513-521.
    • (2004) Curr Opin Rheumatol , vol.16 , pp. 513-521
    • Tsao, B.P.1
  • 74
    • 0033848380 scopus 로고    scopus 로고
    • A susceptibility locus for human systemic lupus erythematosus (hSLE1) on chromosome 2q
    • Lindqvist AK, et al. (2000) A susceptibility locus for human systemic lupus erythematosus (hSLE1) on chromosome 2q. J Autoimmun 14:169-178.
    • (2000) J Autoimmun , vol.14 , pp. 169-178
    • Lindqvist, A.K.1
  • 75
    • 0030738667 scopus 로고    scopus 로고
    • Complete sequence and genomic analysis of murine gammaherpesvirus 68
    • Virgin HW, 4th, et al. (1997) Complete sequence and genomic analysis of murine gammaherpesvirus 68. J Virol 71:5894-5904.
    • (1997) J Virol , vol.71 , pp. 5894-5904
    • Virgin IV, H.W.1
  • 76
    • 12444341806 scopus 로고    scopus 로고
    • Synthetic TLR agonists reveal functional differences between human TLR7 and TLR8
    • Gorden KB, et al. (2005) Synthetic TLR agonists reveal functional differences between human TLR7 and TLR8. J Immunol 174:1259-1268.
    • (2005) J Immunol , vol.174 , pp. 1259-1268
    • Gorden, K.B.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.