Infection of dendritic cells by a γ2-herpesvirus induces functional modulation

Journal of Immunology

Volumn 175, Issue 5, 2005, Pages 3225-3234

  Flaño, Emilio ^a   Kayhan, Basak ^b   Woodland, David L ^b   Blackman, Marcia A ^b  

^a THE RESEARCH INSTITUTE AT NATIONWIDE CHILDREN S HOSPITAL   (United States)

^b TRUDEAU INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; INTERLEUKIN 10;

ALLOIMMUNITY; ANIMAL CELL; ANTIGEN PRESENTATION; ARTICLE; CELL MATURATION; CELL SURFACE; CONTROLLED STUDY; CYTOKINE RELEASE; DENDRITIC CELL; GAMMA HERPES VIRUS 68; HERPES VIRUS; MOUSE; NONHUMAN; PRIORITY JOURNAL; RESPIRATORY TRACT INFECTION; T LYMPHOCYTE ACTIVATION; VIRUS LATENCY;

EID: 23844518957     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.175.5.3225     Document Type: Article

References (67)

1. Mellman, I., and R. M. Steinman. 2001. Dendritic cells: specialized and regulated antigen processing machines. Cell 106: 255-258.
2. Lanzavecchia, A., and F. Sallusto. 2001. Regulation of T cell immunity by dendritic cells. Cell 106: 263-266.
3. Banchereau, J., and R. M. Steinman. 1998. Dendritic cells and the control of immunity. Nature 392: 245-252.
4. Bell, D., J. W. Young, and J. Banchereau. 1999. Dendritic cells. Adv. Immunol. 72: 255-324.
5. Banchereau, J., F. Briere, C. Caux, J. Davoust, S. Lebecque, Y. J. Liu, B. Pulendran, and K. Palucka. 2000. Immunobiology of dendritic cells. Annu. Rev. Immunol. 18: 767-811.
6. Liu, Y. J. 2001. Dendritic cell subsets and lineages, and their functions in innate and adaptive immunity. Cell 106: 259-262.
7. Rescigno, M., and P. Borrow. 2001. The host-pathogen interaction: new themes from dendritic cell biology. Cell 106: 267-270.
8. Palucka, K., and J. Banchereau. 2002. How dendritic cells and microbes interact to elicit or subvert protective immune responses. Curr. Opin. Immunol. 14: 420-431.
9. Moore, P. S., and Y. Chang. 2003. Kaposi's sarcoma-associated herpesvirus immunoevasion and tumorigenesis: two sides of the same coin? Annu. Rev. Microbiol. 57: 609-639.
10. Offermann, M. K. 1999. Consideration of host-viral interactions in the pathogenesis of Kaposi's sarcoma. J. Acquir. Immune Defic. Syndr. 21(Suppl. 1): S58-S65.
11. Rettig, M. B., H. J. Ma, R. A. Vescio, M. Fold, G. Schiller, D. Belson, A. Savage, C. Nishikubo, C. Wu, J. Fraser, J. W. Said, and J. R. Berenson. 1997. Kaposi's sarcoma-associated herpesvirus infection of bone marrow dendritic cells from multiple myeloma patients. Science 276: 1851-1854.
12. Schulz, T. F. 1998. Kaposi's sarcoma-associated herpesvirus (human herpesvirus-8). J. Gen. Virol. 79(Pt. 7): 1573-1591.
13. Stebbing, J., B. Gazzard, S. Portsmouth, F. Gotch, L. Kim, M. Bower, S. Mandalia, R. Binder, P. Srivastava, and S. Patterson. 2003. Disease-associated dendritic cells respond to disease-specific antigens through the common heat shock protein receptor. Blood 102: 1806-1814.
14. Virgin, H. W., P. Latreille, P. Wamsley, K. Hallsworth, K. E. Week, A. J. Dal Canto, and S. H. Speck. 1997. Complete sequence and genomic analysis of murine gammaherpesvirus 68. J. Virol. 71: 5894-5904.
15. Virgin, H. W., and S. H. Speck. 1999. Unraveling immunity to γ-herpesviruses: a new model for understanding the role of immunity in chronic virus infection. Curr. Opin. Immunol. 11: 371-379.
16. Doherty, P. C., J. P. Christensen, G. T. Belz, P. G. Stevenson, and M. Y. Sangster. 2001. Dissecting the host response to a γ-herpesvirus. Philos. Trans. R. Soc. Lond. B Biol. Sci. 356: 581-593.
17. Flaño, E., S. M. Husain, J. T. Sample, D. L. Woodland, and M. A. Blackman. 2000. Latent murine γ-herpesvirus infection is established in activated B cells, dendritic cells, and macrophages. J. Immunol. 165: 1074-1081.
18. Flaño, E., I. J. Kim, J. Moore, D. L. Woodland, and M. A. Blackman. 2003. Differential γ-herpesvirus distribution in distinct anatomical locations and cell subsets during persistent infection in mice. J. Immunol. 170: 3828-3834.
19. Stewart, J. P., E. J. Usherwood, A. Ross, H. Dyson, and T. Nash. 1998. Lung epithelial cells are a major site of murine gammaherpesvirus persistence. J. Exp. Med. 187: 1941-1951.
20. Week, K. E., S. S. Kim, H. W. Virgin, and S. H. Speck. 1999. Macrophages are the major reservoir of latent murine gammaherpesvirus 68 in peritoneal cells. J. Virol. 73: 3273-3283.
21. Flaño, E., I. J. Kim, D. L. Woodland, and M. A. Blackman. 2002. γ-Herpesvirus latency is preferentially maintained in splenic germinal center and memory B cells. J. Exp. Med. 196: 1363-1372.
22. Virgin, H. W., R. M. Presti, X. Y. Li, C. Liu, and S. H. Speck. 1999. Three distinct regions of the murine gammaherpesvirus 68 genome are transcriptionally active in latently infected mice. J. Virol. 73: 2321-2332.
23. Gardella, T., P. Medveczky, T. Sairenji, and C. Mulder. 1984. Detection of circular and linear herpesvirus DNA molecules in mammalian cells by gel electrophoresis. J. Virol. 50: 248-254.
24. Decker, L. L., G. J. Babcock, and D. A. Thorley-Lawson. 2001. Detection and discrimination of latent and replicative herpesvirus infection at the single cell level in vivo. Methods Mol. Biol. 174: 111-116.
25. Flaño, E., Q. Jia, J. Moore, D. L. Woodland, R. Sun, and M. A. Blackman. 2005. Early establishment of γ-herpesvirus latency: implications for immune control. J. Immunol. 174: 4972-4978.
26. Liu, L., E. Flaño, E. J. Usherwood, S. Surman, M. A. Blackman, and D. L. Woodland. 1999. Lytic cycle T cell epitopes are expressed in two distinct phases during MHV-68 infection. J. Immunol. 163: 868-874.
27. Overbergh, L., D. Valckx, M. Waer, and C. Mathieu. 1999. Quantification of murine cytokine mRNAs using real time quantitative reverse transcriptase PCR. Cytokine 11: 305-312.
28. Bechtel, J. T., Y. Liang, J. Hvidding, and D. Ganem. 2003. Host range of Kaposi's sarcoma-associated herpesvirus in cultured cells. J. Virol. 77: 6474-6481.
29. Stevenson, P. G., S. Efstathiou, P. C. Doherty, and P. J. Lehner. 2000. Inhibition of MHC class I-restricted antigen presentation by γ2-herpesviruses. Proc. Natl. Acad. Sci. USA 97: 8455-8460.
30. Lutz, M. B., and G. Schuler. 2002. Immature, semi-mature and fully mature dendritic cells: which signals induce tolerance or immunity? Trends Immunol. 23: 445-449.
31. Alcami, A., and U. H. Koszinowski. 2000. Viral mechanisms of immune evasion. Immunol. Today 21: 447-455.
32. Moore, K. W., R. de Waal Malefyt, R. L. Coffman, and A. O'Garra. 2001. Interleukin-10 and the interleukin-10 receptor. Annu. Rev. Immunol. 19: 683-765.
33. Rickinson, A. B., and E. Kieff. 1996. Epstein-Barr virus. In Fields Virology. D. M. Knipe, B. N. Fields, and P. M. Howley, eds. Lippincott-Raven Publishers, Philadelphia, p. 2397-2446.
34. Peacock, J. W., and K. L. Bost. 2001. Murine gammaherpesvirus-68-induced interleukin-10 increases viral burden, but limits virus-induced splenomegaly and leukocytosis. Immunology 104: 109-117.
35. + T cells aids amplification of a latent gammaherpesvirus. Nat. Immunol. 3: 733-740.
36. + T cells during long-term gammaherpesvirus infection. J. Virol. 75: 7744-7748.
37. Mahanty, S., K. Hutchinson, S. Agarwal, M. McRae, P. E. Rollin, and B. Pulendran. 2003. Cutting edge: impairment of dendritic cells and adaptive immunity by Ebola and Lassa viruses. J. Immunol. 170: 2797-2801.
38. Kakimoto, M., A. Hasegawa, S. Fujita, and M. Yasukawa. 2002. Phenotypic and functional alterations of dendritic cells induced by human herpesvirus 6 infection. J. Virol. 76: 10338-10345.
39. Andrews, D. M., C. E. Andoniou, F. Granucci, P. Ricciardi-Castagnoli, and M. A. Degli-Esposti. 2001. Infection of dendritic cells by murine cytomegalovirus induces functional paralysis. Nat. Immunol. 2: 1077-1084.
40. Engelmayer, J., M. Larsson, M. Subklewe, A. Chahroudi, W. I. Cox, R. M. Steinman, and N. Bhardwaj. 1999. Vaccinia virus inhibits the maturation of human dendritic cells: a novel mechanism of immune evasion. J. Immunol. 163: 6762-6768.
41. Granelli-Piperno, A., A. Golebiowska, C. Trumpfheller, F. P. Siegal, and R. M. Steinman. 2004. HIV-1-infected monocyte-derived dendritic cells do not undergo maturation but can elicit IL-10 production and T cell regulation. Proc. Natl. Acad. Sci. USA 101: 7669-7674.
42. Salio, M., M. Cella, M. Suter, and A. Lanzavecchia. 1999. Inhibition of dendritic cell maturation by herpes simplex virus. Eur. J. Immunol. 29: 3245-3253.
43. Sevilla, N., S. Kunz, A. Holz, H. Lewicki, D. Homann, H. Yamada, K. P. Campbell, J. C. de La Torre, and M. B. Oldstone. 2000. Immunosuppression and resultant viral persistence by specific viral targeting of dendritic cells. J. Exp. Med. 192: 1249-1260.
44. Dutia, B. M., J. P. Stewart, R. A. Clayton, H. Dyson, and A. A. Nash. 1999. Kinetic and phenotypic changes in murine lymphocytes infected with murine gammaherpesvirus-68 in vitro. J. Gen. Virol. 80(Pt. 10): 2729-2736.
45. Stevenson, P. G., and P. C. Doherty. 1999. Non-antigen-specific B-cell activation following murine gammaherpesvirus infection is CD4 independent in vitro but CD4 dependent in vivo. J. Virol. 73: 1075-1079.
46. Nash, A. A., B. M. Dutia, J. P. Stewart, and A. J. Davison. 2001. Natural history of murine gammaherpesvirus infection. Philos. Trans. R. Soc. Lond. B. Biol. Sci. 356: 569-579.
47. Akbari, O., R. H. DeKruyff, and D. T. Umetsu. 2001. Pulmonary dendritic cells producing IL-10 mediate tolerance induced by respiratory exposure to antigen. Nat. Immunol. 2: 725-731.
48. Bickham, K., K. Goodman, C. Paludan, S. Nikiforow, M. L. Tsang, R. M. Steinman, and C. Munz. 2003. Dendritic cells initiate immune control of Epstein-Barr virus transformation of B lymphocytes in vitro. J. Exp. Med. 198: 1653-1663.
49. Li, L., D. Liu, L. Hutt-Fletcher, A. Morgan, M. G. Masucci, and V. Levitsky. 2002. Epstein-Barr virus inhibits the development of dendritic cells by promoting apoptosis of their monocyte precursors in the presence of granulocyte macrophage-colony-stimulating factor and interleukin-4. Blood 99: 3725-3734.
50. Yewdell, J. W., and A. B. Hill. 2002. Viral interference with antigen presentation. Nat. Immunol. 3: 1019-1025.
51. Jones, K. D., Y. Aoki, Y. Chang, P. S. Moore, R. Yarchoan, and G. Tosato. 1999. Involvement of interleukin-10 (IL-10) and viral IL-6 in the spontaneous growth of Kaposi's sarcoma herpesvirus-associated infected primary effusion lymphoma cells. Blood 94: 2871-2879.
52. Burdin, N., C. Peronne, J. Banchereau, and F. Roussel. 1993. Epstein-Barr virus transformation induces B lymphocytes to produce human interleukin 10. J. Exp. Med. 177: 295-304.
53. Blay, J. Y., N. Burdin, F. Rousset, G. Lenoir, P. Biron, T. Philip, J. Banchereau, and M. C. Favrot. 1993. Serum interleukin-10 in non-Hodgkin's lymphoma: a prognostic factor. Blood 82: 2169-2174.
54. Muti, G., C. Klersy, F. Baldanti, S. Granata, P. Oreste, L. Pezzetti, M. Gatti, L. Gargantini, M. Caramella, V. Mancini, G. Gerna, and E. Morra. 2003. Epstein-Barr virus (EBV) load and interleukin-10 in EBV-positive and EBV-negative post-transplant lymphoproliferative disorders. Br. J. Haematol. 122: 927-933.
55. Arena, A., M. C. Liberto, D. Iannello, A. B. Capozza, and A. Foca. 1999. Altered cytokine production after human herpes virus type 6 infection. New Microbiol. 22: 293-300.
56. van Den Broek, M., M. F. Bachmann, G. Kohler, M. Barner, R. Escher, R. Zinkernagel, and M. Kopf. 2000. IL-4 and IL-10 antagonize IL-12-mediated protection against acute vaccinia virus infection with a limited role of IFN-γ and nitric oxide synthetase 2. J. Immunol. 164: 371-378.
57. Stockl, J., H. Vetr, O. Majdic, G. Zlabinger, E. Kuechler, and W. Knapp. 1999. Human major group rhinoviruses down-modulate the accessory function of monocytes by inducing IL-10. J. Clin. Invest. 104: 957-965.
58. Redpath, S., A. Angulo, N. R. Gascoigne, and P. Ghazal. 1999. Murine cytomegalovirus infection down-regulates MHC class II expression on macrophages by induction of IL-10. J. Immunol. 162: 6701-6707.
59. Lin, M. T., D. R. Hinton, B. Parra, S. A. Stohlman, and R. C. van der Veen. 1998. The role of IL-10 in mouse hepatitis virus-induced demyelinating encephalomyelitis. Virology 245: 270-280.
60. + T cells. J. Immunol. 162: 1624-1632.
61. Boname, J. M., and P. G. Stevenson. 2001. MHC class I ubiquitination by a viral PHD/LAP finger protein. Immunity 15: 627-636.
62. Jugovic, P., A. M. Hill, R. Tomazin, H. Ploegh, and D. C. Johnson. 1998. Inhibition of major histocompatibility complex class I antigen presentation in pig and primate cells by herpes simplex virus type 1 and 2 ICP47. J. Virol. 72: 5076-5084.
63. Raftery, M. J., C. K. Behrens, A. Muller, P. H. Krammer, H. Walczak, and G. Schonrich. 1999. Herpes simplex virus type 1 infection of activated cytotoxic T cells: induction of fratricide as a mechanism of viral immune evasion. J. Exp. Med. 190: 1103-1114.
64. Mikloska, Z., L. Bosnjak, and A. L. Cunningham. 2001. Immature monocyte-derived dendritic cells are productively infected with herpes simplex virus type 1. J. Virol. 75: 5958-5964.
65. + T cell responses from primary to persistent phases of Epstein-Barr virus infection. J. Exp. Med. 195: 893-905.
66. + T cell response during acute and persistent murine γ-herpesvirus infection. Eur. J. Immunol. 29: 1059-1067.
67. Obar, J. J., S. G. Crist, D. C. Gondek, and E. J. Usherwood. 2004. Different functional capacities of latent and lytic antigen-specific CD8 T cells in murine gammaherpesvirus infection. J. Immunol. 172: 1213-1219.