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Volumn 28, Issue 3, 2012, Pages 311-315

Metabolic homeostasis as the cornerstone of aging;L'Homéostasie métabolique au cœur du vieillissement

Author keywords

[No Author keywords available]

Indexed keywords

CAENORHABDITIS ELEGANS PROTEIN; CARRIER PROTEIN; INSULIN; PROTEIN KINASE; RESVERATROL; SLCF 1 PROTEIN, C ELEGANS; SLCF-1 PROTEIN, C ELEGANS; SOMATOMEDIN C; STILBENE DERIVATIVE; TARGET OF RAPAMYCIN KINASE;

EID: 84860817542     PISSN: 07670974     EISSN: 19585381     Source Type: Journal    
DOI: 10.1051/medsci/2012283020     Document Type: Review
Times cited : (4)

References (40)
  • 1
    • 0025004091 scopus 로고
    • Increased life-span of age-1 mutants in Caenorhabditis elegans and lower Gompertz rate of aging
    • Johnson TE. Increased life-span of age-1 mutants in Caenorhabditis elegans and lower Gompertz rate of aging. Science 1990;249:908-12.
    • (1990) Science , vol.249 , pp. 908-912
    • Johnson, T.E.1
  • 2
    • 0027771804 scopus 로고
    • A C. elegans mutant that lives twice as long as wild type
    • DOI 10.1038/366461a0
    • Kenyon C, Chang J, Gensch E, et al. A C. elegans mutant that lives twice as long as wild type. Nature 1993;366:461-4. (Pubitemid 24013878)
    • (1993) Nature , vol.366 , Issue.6454 , pp. 461-464
    • Kenyon, C.1    Chang, J.2    Gensch, E.3    Rudner, A.4    Tabtiang, R.5
  • 3
    • 0037942739 scopus 로고    scopus 로고
    • Extended longevity in mice lacking the insulin receptor in adipose tissue
    • DOI 10.1126/science.1078223
    • Blüher M, Kahn BB, Kahn CR. Extended longevity in mice lacking the insulin receptor in adipose tissue. Science 2003;299:572-4. (Pubitemid 36135156)
    • (2003) Science , vol.299 , Issue.5606 , pp. 572-574
    • Bluher, M.1    Kahn, B.B.2    Kahn, C.R.3
  • 5
    • 0036584593 scopus 로고    scopus 로고
    • Genetic analysis of insulin signaling in Drosophila
    • PII S1043276001005483
    • Garofalo RS. Genetic analysis of insulin signaling in Drosophila. Trends Endocrinol Metab 2002;13:156-62. (Pubitemid 36733989)
    • (2002) Trends in Endocrinology and Metabolism , vol.13 , Issue.4 , pp. 156-162
    • Garofalo, R.S.1
  • 6
    • 0034613164 scopus 로고    scopus 로고
    • Regulation of C. elegans life-span by insulinlike signaling in the nervous system
    • Wolkow CA, Kimura KD, Lee MS, Ruvkun G. Regulation of C. elegans life-span by insulinlike signaling in the nervous system. Science 2000;290:147-50.
    • (2000) Science , vol.290 , pp. 147-150
    • Wolkow, C.A.1    Kimura, K.D.2    Lee, M.S.3    Ruvkun, G.4
  • 7
    • 2942563805 scopus 로고    scopus 로고
    • Drosophila dFOXO controls lifespan and regulates insulin signalling in brain and fat body
    • DOI 10.1038/nature02549
    • Hwangbo DS, Gershman B, Gersham B, et al. Drosophila dFOXO controls lifespan and regulates insulin signalling in brain and fat body. Nature 2004;429:562-6. (Pubitemid 38737660)
    • (2004) Nature , vol.429 , Issue.6991 , pp. 562-566
    • Hwangbo, D.S.1    Garsham, B.2    Tu, M.-P.3    Palmer, M.4    Tatar, M.5
  • 8
    • 54949143977 scopus 로고    scopus 로고
    • Brain IGF-1 receptors control mammalian growth and lifespan through a neuroendocrine mechanism
    • Kappeler L, De Magalhaes Filho C, Dupont J, et al. Brain IGF-1 receptors control mammalian growth and lifespan through a neuroendocrine mechanism. PLoS Biol 2008;6:e254.
    • (2008) PLoS Biol , vol.6
    • Kappeler, L.1    De Magalhaes Filho, C.2    Dupont, J.3
  • 9
    • 77955747346 scopus 로고    scopus 로고
    • With TOR, less is more: A key role for the conserved nutrientsensing TOR pathway in aging
    • Kapahi P, Chen D, Rogers AN, et al. With TOR, less is more: a key role for the conserved nutrientsensing TOR pathway in aging. Cell Metab 2010;11:453-65.
    • (2010) Cell Metab , vol.11 , pp. 453-465
    • Kapahi, P.1    Chen, D.2    Rogers, A.N.3
  • 10
    • 0024656069 scopus 로고
    • The effect of retarded growth upon the length of life span and upon the ultimate body size
    • McCay CM, Maynard LA. The effect of retarded growth upon the length of life span and upon the ultimate body size. Nutrition 1935;5:155-72.
    • (1935) Nutrition , vol.5 , pp. 155-172
    • McCay, C.M.1    Maynard, L.A.2
  • 11
    • 67650439330 scopus 로고    scopus 로고
    • Caloric Restriction delays disease onset and mortality in Rhesus monkeys
    • Colman RJ, Anderson RM, Johnson SC, et al. Caloric Restriction delays disease onset and mortality in Rhesus monkeys. Science 2009;325:201-4.
    • (2009) Science , vol.325 , pp. 201-204
    • Colman, R.J.1    Anderson, R.M.2    Johnson, S.C.3
  • 12
    • 50649099122 scopus 로고    scopus 로고
    • Aging and survival: The genetics of life span extension by dietary restriction
    • Mair W, Dillin A. Aging and survival: the genetics of life span extension by dietary restriction. Annu Rev Biochem 2008;77:727-54.
    • (2008) Annu Rev Biochem , vol.77 , pp. 727-754
    • Mair, W.1    Dillin, A.2
  • 14
    • 34249888736 scopus 로고    scopus 로고
    • PHA-4/Foxa mediates diet-restriction-induced longevity of C. elegans
    • DOI 10.1038/nature05837, PII NATURE05837
    • Panowski SH, Wolff S, Aguilaniu H, et al. PHA-4/Foxa mediates dietrestriction-induced longevity of C. elegans. Nature 2007;447:550-5. (Pubitemid 46868041)
    • (2007) Nature , vol.447 , Issue.7144 , pp. 550-555
    • Panowski, S.H.1    Wolff, S.2    Aguilaniu, H.3    Durieux, J.4    Dillin, A.5
  • 15
    • 33646731782 scopus 로고    scopus 로고
    • Targeted disruption of growth hormone receptor interferes with the beneficial actions of calorie restriction
    • Bonkowski MS, Rocha JS, Masternak MM, et al. Targeted disruption of growth hormone receptor interferes with the beneficial actions of calorie restriction. Proc Natl Acad Sci USA 2006;103:7901-5.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 7901-7905
    • Bonkowski, M.S.1    Rocha, J.S.2    Masternak, M.M.3
  • 16
    • 76249097841 scopus 로고    scopus 로고
    • Genetic variation in the murine lifespan response to dietary restriction: From life extension to life shortening
    • Liao CY, Rikke BA, Johnson TE, et al. Genetic variation in the murine lifespan response to dietary restriction: from life extension to life shortening. Aging Cell; 9:92-5.
    • Aging Cell , vol.9 , pp. 92-95
    • Liao, C.Y.1    Rikke, B.A.2    Johnson, T.E.3
  • 17
  • 19
    • 67650944993 scopus 로고    scopus 로고
    • Rapamycin fed late in life extends lifespan in genetically heterogeneous mice
    • Harrison DE, Strong R, Sharp ZD, et al. Rapamycin fed late in life extends lifespan in genetically heterogeneous mice. Nature 2009;460:392-5.
    • (2009) Nature , vol.460 , pp. 392-395
    • Harrison, D.E.1    Strong, R.2    Sharp, Z.D.3
  • 20
    • 77953463398 scopus 로고    scopus 로고
    • Protein degradation, aggregation, and misfolding
    • Cuervo AM, Wong ES, Martinez-Vicente M. Protein degradation, aggregation, and misfolding. Mov Disord 2010;25(suppl 1):S49-54.
    • (2010) Mov Disord , vol.25 , Issue.1 SUPPL.
    • Cuervo, A.M.1    Wong, E.S.2    Martinez-Vicente, M.3
  • 22
    • 78649521247 scopus 로고    scopus 로고
    • Calorie restriction reduces oxidative stress by SIRT3-mediated SOD2 activation
    • Qiu X, Brown K, Hirschey MD, et al. Calorie restriction reduces oxidative stress by SIRT3-mediated SOD2 activation. Cell Metab 2010;12:662-7.
    • (2010) Cell Metab , vol.12 , pp. 662-667
    • Qiu, X.1    Brown, K.2    Hirschey, M.D.3
  • 23
    • 34249891333 scopus 로고    scopus 로고
    • Two neurons mediate diet-restriction-induced longevity in C. elegans
    • DOI 10.1038/nature05904, PII NATURE05904
    • Bishop NA, Guarente L. Two neurons mediate diet-restriction-induced longevity in C. elegans. Nature 2007;447:545-9. (Pubitemid 46868049)
    • (2007) Nature , vol.447 , Issue.7144 , pp. 545-549
    • Bishop, N.A.1    Guarente, L.2
  • 24
  • 25
    • 67149107430 scopus 로고    scopus 로고
    • HIF-1 modulates dietary restriction-mediated lifespan extension via IRE-1 in Caenorhabditis elegans
    • Chen D, Thomas EL, Kapahi P. HIF-1 modulates dietary restriction-mediated lifespan extension via IRE-1 in Caenorhabditis elegans. PLoS Genet 2009;5:e1000486.
    • (2009) PLoS Genet , vol.5
    • Chen, D.1    Thomas, E.L.2    Kapahi, P.3
  • 26
    • 0020044308 scopus 로고
    • Dietary restriction in mice beginning at 1 year of age: Effect on life-span and spontaneous cancer incidence
    • Weindruch R, Walford RL. Dietary restriction in mice beginning at 1 year of age: effect on life-span and spontaneous cancer incidence. Science 1982;215:1415-8. (Pubitemid 12129729)
    • (1982) Science , vol.215 , Issue.4538 , pp. 1415-1418
    • Weindruch, R.1    Walford, R.L.2
  • 27
    • 12444296522 scopus 로고    scopus 로고
    • The human tumour suppressor PTEN regulates longevity and dauer formation in Caenorhabditis elegans
    • DOI 10.1038/sj.onc.1207978
    • Solari F, Bourbon-Piffaut A, Masse I, et al. The human tumour suppressor PTEN regulates longevity and dauer formation in Caenorhabditis elegans. Oncogene 2005;24:20-7. (Pubitemid 40143861)
    • (2005) Oncogene , vol.24 , Issue.1 , pp. 20-27
    • Solari, F.1    Bourbon-Piffaut, A.2    Masse, I.3    Payrastre, B.4    Chan, A.M.-L.5    Billaud, M.6
  • 28
    • 53749097353 scopus 로고    scopus 로고
    • A novel role for the SMG-1 kinase in lifespan and oxidative stress resistance in Caenorhabditis elegans
    • Masse I, Molin L, Mouchiroud L, et al. A novel role for the SMG-1 kinase in lifespan and oxidative stress resistance in Caenorhabditis elegans. PLoS One 2008;3:e3354.
    • (2008) PLoS One , vol.3
    • Masse, I.1    Molin, L.2    Mouchiroud, L.3
  • 29
    • 78651276219 scopus 로고    scopus 로고
    • Pyruvate imbalance mediates metabolic reprogramming and mimics lifespan extension by dietary restriction in Caenorhabditis elegans
    • Mouchiroud L, Molin L, Kasturi P, et al. Pyruvate imbalance mediates metabolic reprogramming and mimics lifespan extension by dietary restriction in Caenorhabditis elegans. Aging Cell 2011;10:39-54.
    • (2011) Aging Cell , vol.10 , pp. 39-54
    • Mouchiroud, L.1    Molin, L.2    Kasturi, P.3
  • 30
    • 64749108996 scopus 로고    scopus 로고
    • Tumours with PI3K activation are resistant to dietary restriction
    • Kalaany NY, Sabatini DM. Tumours with PI3K activation are resistant to dietary restriction. Nature 2009;458:725-31.
    • (2009) Nature , vol.458 , pp. 725-731
    • Kalaany, N.Y.1    Sabatini, D.M.2
  • 31
    • 2942593991 scopus 로고    scopus 로고
    • ROS stress in cancer cells and therapeutic implications
    • DOI 10.1016/j.drup.2004.01.004
    • Pelicano H, Carney D, Huang P. ROS stress in cancer cells and therapeutic implications. Drug Resist Updat 2004;7:97-110. (Pubitemid 38736063)
    • (2004) Drug Resistance Updates , vol.7 , Issue.2 , pp. 97-110
    • Pelicano, H.1    Carney, D.2    Huang, P.3
  • 32
    • 77951176737 scopus 로고    scopus 로고
    • Extending healthy life span: From yeast to humans
    • Fontana L, Partridge L, Longo VD. Extending healthy life span: from yeast to humans. Science 2010;328:321-6.
    • (2010) Science , vol.328 , pp. 321-326
    • Fontana, L.1    Partridge, L.2    Longo, V.D.3
  • 33
    • 78649872952 scopus 로고    scopus 로고
    • Life span extension by resveratrol, rapamycin, and metformin: The promise of dietary restriction mimetics for an healthy aging
    • Mouchiroud L, Molin L, Dalliere N, Solari F. Life span extension by resveratrol, rapamycin, and metformin: the promise of dietary restriction mimetics for an healthy aging. Biofactors 2010;36:377-82.
    • (2010) Biofactors , vol.36 , pp. 377-382
    • Mouchiroud, L.1    Molin, L.2    Dalliere, N.3    Solari, F.4
  • 34
    • 79959435204 scopus 로고    scopus 로고
    • Recent advances in the discovery of smallmolecule ATP competitive mTOR inhibitors: A patent review
    • Zask A, Verheijen JC, Richard DJ. Recent advances in the discovery of smallmolecule ATP competitive mTOR inhibitors: a patent review. Expert Opin Ther Pat 2011;21:1109-27.
    • (2011) Expert Opin Ther Pat , vol.21 , pp. 1109-1127
    • Zask, A.1    Verheijen, J.C.2    Richard, D.J.3
  • 36
    • 79955749452 scopus 로고    scopus 로고
    • The diabetes drug liraglutide prevents degenerative processes in a mouse model of Alzheimer's disease
    • McClean PL, Parthsarathy V, Faivre E, Holscher C. The diabetes drug liraglutide prevents degenerative processes in a mouse model of Alzheimer's disease. J Neurosci 2011;31:6587-94.
    • (2011) J Neurosci , vol.31 , pp. 6587-6594
    • McClean, P.L.1    Parthsarathy, V.2    Faivre, E.3    Holscher, C.4
  • 37
    • 71449108913 scopus 로고    scopus 로고
    • Reduced IGF-1 signaling delays age-associated proteotoxicity in mice
    • Cohen E, Paulsson JF, Blinder P, et al. Reduced IGF-1 signaling delays age-associated proteotoxicity in mice. Cell 2009;139:1157-69.
    • (2009) Cell , vol.139 , pp. 1157-1169
    • Cohen, E.1    Paulsson, J.F.2    Blinder, P.3
  • 38
    • 84860805838 scopus 로고    scopus 로고
    • Bien vieillir: La voie de signalisation insuline-FOXO et la Longévité
    • Brunet A. Bien vieillir: la voie de signalisation insuline-FOXO et la longévité. Med Sci (Paris) 2012;28:316-20.
    • (2012) Med Sci (Paris) , vol.28 , pp. 316-320
    • Brunet, A.1
  • 40
    • 33746196817 scopus 로고    scopus 로고
    • Du cancer au traitement du diabète: Le suppresseur de tumeur LKB1 comme nouvelle cible pharmacologique
    • Foretz M, Guigas B, Viollet B. Du cancer au traitement du diabète: le suppresseur de tumeur LKB1 comme nouvelle cible pharmacologique. Med Sci (Paris) 2006;22:348-50.
    • (2006) Med Sci (Paris) , vol.22 , pp. 348-350
    • Foretz, M.1    Guigas, B.2    Viollet, B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.