Apigenin induces apoptosis via tumor necrosis factor receptor- and Bcl-2-mediated pathway and enhances susceptibility of head and neck squamous cell carcinoma to 5-fluorouracil and cisplatin

Biochimica et Biophysica Acta - General Subjects

Volumn 1820, Issue 7, 2012, Pages 1081-1091

  Chan, Leong Perng ^a,b   Chou, Tzung Han ^c   Ding, Hsiou Yu ^d   Chen, Pin Ru ^d   Chiang, Feng Yu ^b   Kuo, Po Lin ^a,b   Liang, Chia Hua ^d  

^a KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^b KAOHSIUNG MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^c NATIONAL YUNLIN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Taiwan)

^d CHIA NAN UNIVERSITY OF PHARMACY AND SCIENCE   (Taiwan)

Author keywords

5 Fluorouracil; Apigenin; Cisplatin; Death receptor; Human head and neck squamous cell carcinoma

Indexed keywords

APIGENIN; ASCORBIC ACID; CASPASE; CISPLATIN; DEATH RECEPTOR; FLUOROURACIL; GLUTATHIONE; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; TROLOX C; TUMOR NECROSIS FACTOR RECEPTOR; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND RECEPTOR;

ANIMAL CELL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ANTIOXIDANT ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CANCER GROWTH; CANCER INHIBITION; CELL CLONE; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL PROTECTION; CELL SURVIVAL; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG POTENCY; DRUG POTENTIATION; DRUG SENSITIVITY; HEAD AND NECK SQUAMOUS CELL CARCINOMA; HUMAN; HUMAN CELL; LIPID PEROXIDATION; MITOCHONDRION; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; UPREGULATION;

ANIMALS; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; APIGENIN; APOPTOSIS; BLOTTING, WESTERN; CARCINOMA, SQUAMOUS CELL; CASPASES; CELL CYCLE CHECKPOINTS; CELL SURVIVAL; CELLS, CULTURED; CISPLATIN; DRUG SYNERGISM; FLOW CYTOMETRY; FLUOROURACIL; HEAD AND NECK NEOPLASMS; HUMANS; LIPID PEROXIDATION; LIVER; MELANOMA; MICE; PROTO-ONCOGENE PROTEINS C-BCL-2; REACTIVE OXYGEN SPECIES; RECEPTORS, TUMOR NECROSIS FACTOR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SKIN NEOPLASMS; TNF-RELATED APOPTOSIS-INDUCING LIGAND;

MURINAE;

EID: 84860797409     PISSN: 03044165     EISSN: 18728006     Source Type: Journal    
DOI: 10.1016/j.bbagen.2012.04.013     Document Type: Article

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