-
1
-
-
2442561553
-
Apoptosis as a novel target for cancer chemoprevention
-
Sun S.Y., Hail Jr. N., and Lotan R. Apoptosis as a novel target for cancer chemoprevention. J Natl Cancer Inst 96 (2004) 662-672
-
(2004)
J Natl Cancer Inst
, vol.96
, pp. 662-672
-
-
Sun, S.Y.1
Hail Jr., N.2
Lotan, R.3
-
2
-
-
28944450865
-
Oncogenes as novel targets for cancer therapy (part IV): regulators of the cell cycle and apoptosis
-
Zhang Z., Li M., Rayburn E.R., Hill D.L., Zhang R., and Wang H. Oncogenes as novel targets for cancer therapy (part IV): regulators of the cell cycle and apoptosis. Am J Pharmacogenomics 5 (2005) 397-407
-
(2005)
Am J Pharmacogenomics
, vol.5
, pp. 397-407
-
-
Zhang, Z.1
Li, M.2
Rayburn, E.R.3
Hill, D.L.4
Zhang, R.5
Wang, H.6
-
3
-
-
28544443984
-
Promoting apoptosis as a strategy for cancer drug discovery
-
Fesik S.W. Promoting apoptosis as a strategy for cancer drug discovery. Nat Rev Cancer 5 (2005) 876-885
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 876-885
-
-
Fesik, S.W.1
-
4
-
-
2442520504
-
Apoptosis in human cancer cells
-
Yu J., and Zhang L. Apoptosis in human cancer cells. Curr Opin Oncol 16 (2004) 19-24
-
(2004)
Curr Opin Oncol
, vol.16
, pp. 19-24
-
-
Yu, J.1
Zhang, L.2
-
5
-
-
0034851475
-
Flavonoid (myricetin, quercetin, kaempferol, luteolin, and apigenin) content of edible tropical plants
-
Miean K.H., and Mohamed S. Flavonoid (myricetin, quercetin, kaempferol, luteolin, and apigenin) content of edible tropical plants. J Agric Food Chem 49 (2001) 3106-3112
-
(2001)
J Agric Food Chem
, vol.49
, pp. 3106-3112
-
-
Miean, K.H.1
Mohamed, S.2
-
6
-
-
33646495775
-
Apigenin: is it a pro- or anti-inflammatory agent?
-
Soares R., and Azevedo I. Apigenin: is it a pro- or anti-inflammatory agent?. Am J Pathol 168 (2006) 1762-1763
-
(2006)
Am J Pathol
, vol.168
, pp. 1762-1763
-
-
Soares, R.1
Azevedo, I.2
-
7
-
-
0027530322
-
Skin anti-inflammatory activity of apigenin-7-glucoside in rats
-
Fuchs J., and Milbradt R. Skin anti-inflammatory activity of apigenin-7-glucoside in rats. Arzneimittelforschung 43 (1993) 370-372
-
(1993)
Arzneimittelforschung
, vol.43
, pp. 370-372
-
-
Fuchs, J.1
Milbradt, R.2
-
8
-
-
2442701285
-
Protective role of Apigenin on the status of lipid peroxidation and antioxidant defense against hepatocarcinogenesis in Wistar albino rats
-
Singh J.P., Selvendiran K., Banu S.M., and Padmavathi R. Protective role of Apigenin on the status of lipid peroxidation and antioxidant defense against hepatocarcinogenesis in Wistar albino rats. Phytomedicine 11 (2004) 309-314
-
(2004)
Phytomedicine
, vol.11
, pp. 309-314
-
-
Singh, J.P.1
Selvendiran, K.2
Banu, S.M.3
Padmavathi, R.4
-
9
-
-
0035002506
-
Study of antioxidant effect of apigenin, luteolin and quercetin by DNA protective method
-
Romanova D., Vachalkova A., Cipak L., Ovesna Z., and Rauko P. Study of antioxidant effect of apigenin, luteolin and quercetin by DNA protective method. Neoplasma 48 (2001) 104-107
-
(2001)
Neoplasma
, vol.48
, pp. 104-107
-
-
Romanova, D.1
Vachalkova, A.2
Cipak, L.3
Ovesna, Z.4
Rauko, P.5
-
10
-
-
33750632619
-
The flavonoid apigenin inhibits the proliferation of prostatic stromal cells via the MAPK-pathway and cell-cycle arrest in G1/S
-
Bektic J., Guggenberger R., Spengler B., Christiffel V., Pelzer A., Berger A.P., et al. The flavonoid apigenin inhibits the proliferation of prostatic stromal cells via the MAPK-pathway and cell-cycle arrest in G1/S. Maturitas 55s (2006) s37-s46
-
(2006)
Maturitas
, vol.55 s
-
-
Bektic, J.1
Guggenberger, R.2
Spengler, B.3
Christiffel, V.4
Pelzer, A.5
Berger, A.P.6
-
11
-
-
0034819073
-
Apigenin acts on the tumor cell invasion process and regulates protease production
-
Lindenmeyer F., Li H., Menashi S., Soria C., and Lu H. Apigenin acts on the tumor cell invasion process and regulates protease production. Nutr Cancer 39 (2001) 139-147
-
(2001)
Nutr Cancer
, vol.39
, pp. 139-147
-
-
Lindenmeyer, F.1
Li, H.2
Menashi, S.3
Soria, C.4
Lu, H.5
-
12
-
-
0035812747
-
Selective growth-inhibitory, cell-cycle deregulatory and apoptotic response of apigenin in normal versus human prostate carcinoma cells
-
Gupta S., Afag F., and Mukhtar H. Selective growth-inhibitory, cell-cycle deregulatory and apoptotic response of apigenin in normal versus human prostate carcinoma cells. Biochem Biophys Res Commun 287 (2001) 914-920
-
(2001)
Biochem Biophys Res Commun
, vol.287
, pp. 914-920
-
-
Gupta, S.1
Afag, F.2
Mukhtar, H.3
-
13
-
-
33646828739
-
Anti-proliferative effect of apigenin and its apoptotic induction in human Hep G2 cells
-
Chiang L.C., Ng L.T., Lin I.C., Kuo P.L., and Lin C.C. Anti-proliferative effect of apigenin and its apoptotic induction in human Hep G2 cells. Cancer Lett 237 (2006) 207-214
-
(2006)
Cancer Lett
, vol.237
, pp. 207-214
-
-
Chiang, L.C.1
Ng, L.T.2
Lin, I.C.3
Kuo, P.L.4
Lin, C.C.5
-
14
-
-
0025068737
-
Isolation and studies of the mutagenic activity in the Ames test of flavonoids naturally occurring in medical herbs
-
Czeczot H., Tuek B., Kusztelak J., Szymczyk T., Dobrowolska B., Glinkowska G., et al. Isolation and studies of the mutagenic activity in the Ames test of flavonoids naturally occurring in medical herbs. Mutat Res 240 (1990) 209-216
-
(1990)
Mutat Res
, vol.240
, pp. 209-216
-
-
Czeczot, H.1
Tuek, B.2
Kusztelak, J.3
Szymczyk, T.4
Dobrowolska, B.5
Glinkowska, G.6
-
15
-
-
0035059767
-
Apigenin inhibits growth and induces G2/M arrest by modulating cyclin-CDK regulators and ERK MAP kinase activation in breast carcinoma cells
-
Yin F., Giuliano A.E., Law R.E., and Van Herle A.J. Apigenin inhibits growth and induces G2/M arrest by modulating cyclin-CDK regulators and ERK MAP kinase activation in breast carcinoma cells. Anticancer Res 21 (2001) 413-420
-
(2001)
Anticancer Res
, vol.21
, pp. 413-420
-
-
Yin, F.1
Giuliano, A.E.2
Law, R.E.3
Van Herle, A.J.4
-
16
-
-
0038807711
-
Flavonoids: promising anticancer agents
-
Ren W., Oiao Z., Wang H., Zhu L., and Zhang L. Flavonoids: promising anticancer agents. Med Res Rev 23 (2003) 519-534
-
(2003)
Med Res Rev
, vol.23
, pp. 519-534
-
-
Ren, W.1
Oiao, Z.2
Wang, H.3
Zhu, L.4
Zhang, L.5
-
17
-
-
0036401813
-
Flavonoids as anticancer agents: structure-activity relationship study
-
Lopez-Lazaro M. Flavonoids as anticancer agents: structure-activity relationship study. Curr Med Chem Anticancer Agents 2 (2002) 691-714
-
(2002)
Curr Med Chem Anticancer Agents
, vol.2
, pp. 691-714
-
-
Lopez-Lazaro, M.1
-
18
-
-
33645808244
-
Natural flavonoids targeting deregulated cell cycle progression in cancer cells
-
Singh R.P., and Agarwal R. Natural flavonoids targeting deregulated cell cycle progression in cancer cells. Curr Drug Targets 7 (2006) 345-354
-
(2006)
Curr Drug Targets
, vol.7
, pp. 345-354
-
-
Singh, R.P.1
Agarwal, R.2
-
19
-
-
0033867027
-
Estrogenic activity of flavonoids in mice. The importance of estrogen receptor distribution, metabolism and bioavailability
-
Breinholt V., Hossaini A., Svendsen G.W., Brouwer C., and Nielsen E. Estrogenic activity of flavonoids in mice. The importance of estrogen receptor distribution, metabolism and bioavailability. Food Chem Toxicol 38 (2000) 555-564
-
(2000)
Food Chem Toxicol
, vol.38
, pp. 555-564
-
-
Breinholt, V.1
Hossaini, A.2
Svendsen, G.W.3
Brouwer, C.4
Nielsen, E.5
-
20
-
-
0033933197
-
Cell-cycle arrest at G2/M and growth inhibition by apigenin in human colon carcinoma cell lines
-
Wang W., Heideman L., Chung C.S., Pelling J.C., Koehler K.J., and Birt D.F. Cell-cycle arrest at G2/M and growth inhibition by apigenin in human colon carcinoma cell lines. Mol Carcinog 28 (2000) 102-110
-
(2000)
Mol Carcinog
, vol.28
, pp. 102-110
-
-
Wang, W.1
Heideman, L.2
Chung, C.S.3
Pelling, J.C.4
Koehler, K.J.5
Birt, D.F.6
-
21
-
-
0034698069
-
Cell cycle-regulated phosphorylation of the human SIX1 homeodomain protein
-
Ford H.L., Landesman-Bollag E., Dacwag C.S., Stukenberg P.T., Pardee A.B., and Seldin D.C. Cell cycle-regulated phosphorylation of the human SIX1 homeodomain protein. J Biol Chem 275 (2000) 22245-22254
-
(2000)
J Biol Chem
, vol.275
, pp. 22245-22254
-
-
Ford, H.L.1
Landesman-Bollag, E.2
Dacwag, C.S.3
Stukenberg, P.T.4
Pardee, A.B.5
Seldin, D.C.6
-
22
-
-
0034807826
-
Dietary agents in cancer prevention: flavonoids and isoflavonoids
-
Birt D.F., Hendrich S., and Wang W. Dietary agents in cancer prevention: flavonoids and isoflavonoids. Pharmacol Ther 90 (2001) 157-177
-
(2001)
Pharmacol Ther
, vol.90
, pp. 157-177
-
-
Birt, D.F.1
Hendrich, S.2
Wang, W.3
-
23
-
-
0029826521
-
The chemopreventive flavonoid apigenin induces G2/M arrest in keratinocytes
-
Lepley D.M., Li B., Birt D.F., and Pelling J.C. The chemopreventive flavonoid apigenin induces G2/M arrest in keratinocytes. Carcinogenesis 17 (1996) 2367-2375
-
(1996)
Carcinogenesis
, vol.17
, pp. 2367-2375
-
-
Lepley, D.M.1
Li, B.2
Birt, D.F.3
Pelling, J.C.4
-
24
-
-
0024390591
-
Reversible tyrosine phosphorylation of cdc2: dephosphorylation accompanies activation during entry into mitosis
-
Morla A.O., Draetta G., Beach D., and Wang J.Y. Reversible tyrosine phosphorylation of cdc2: dephosphorylation accompanies activation during entry into mitosis. Cell 58 (1989) 193-203
-
(1989)
Cell
, vol.58
, pp. 193-203
-
-
Morla, A.O.1
Draetta, G.2
Beach, D.3
Wang, J.Y.4
-
25
-
-
0026580389
-
Oscillation of MPF is accompanied by periodic association between cdc25 and cdc2-cyclin B
-
Jessus C., and Beach D. Oscillation of MPF is accompanied by periodic association between cdc25 and cdc2-cyclin B. Cell 68 (1992) 323-332
-
(1992)
Cell
, vol.68
, pp. 323-332
-
-
Jessus, C.1
Beach, D.2
-
26
-
-
23244449448
-
Induction of apoptosis by a novel indirubin-5-nitro-3¢-monoxime, a CDK inhibitor, in human lung cancer cells
-
Lee J.W., Moon M.J., Min H.Y., Chung H.J., Park E.J., Park H.J., et al. Induction of apoptosis by a novel indirubin-5-nitro-3¢-monoxime, a CDK inhibitor, in human lung cancer cells. Bioorg Med Chem Lett 15 (2005) 3948-3952
-
(2005)
Bioorg Med Chem Lett
, vol.15
, pp. 3948-3952
-
-
Lee, J.W.1
Moon, M.J.2
Min, H.Y.3
Chung, H.J.4
Park, E.J.5
Park, H.J.6
-
27
-
-
0036124768
-
Stat1-dependent, p53-independent expression of p21(waf1) modulates oxysterol-induced apoptosis
-
Agrawal S., Agarwal M.L., Chatterjee-Kishore M., Stark G.R., and Chisolm G.M. Stat1-dependent, p53-independent expression of p21(waf1) modulates oxysterol-induced apoptosis. Mol Cell Biol 22 (2005) 1981-1992
-
(2005)
Mol Cell Biol
, vol.22
, pp. 1981-1992
-
-
Agrawal, S.1
Agarwal, M.L.2
Chatterjee-Kishore, M.3
Stark, G.R.4
Chisolm, G.M.5
-
28
-
-
0035821788
-
p21 Waf1/Cip1 can protect human colon carcinoma cells against p53-dependent and p53-independent apoptosis induced by natural chemopreventive and therapeutic agents
-
Mahyar-Roemer M., and Roemer K. p21 Waf1/Cip1 can protect human colon carcinoma cells against p53-dependent and p53-independent apoptosis induced by natural chemopreventive and therapeutic agents. Oncogene 20 (2001) 3387-3398
-
(2001)
Oncogene
, vol.20
, pp. 3387-3398
-
-
Mahyar-Roemer, M.1
Roemer, K.2
-
29
-
-
0033532174
-
The ability of p53 to activate downstream genes p21(WAF1/cip1) and MDM2, and cell cycle arrest following DNA damage is delayed and attenuated in scid cells deficient in the DNA-dependent protein kinase
-
Kachnic L.A., Wu B., Wunsch H., MeKeel K.L., DeFrank J.S., Tang W., et al. The ability of p53 to activate downstream genes p21(WAF1/cip1) and MDM2, and cell cycle arrest following DNA damage is delayed and attenuated in scid cells deficient in the DNA-dependent protein kinase. J Biol Chem 274 (1999) 13111-13117
-
(1999)
J Biol Chem
, vol.274
, pp. 13111-13117
-
-
Kachnic, L.A.1
Wu, B.2
Wunsch, H.3
MeKeel, K.L.4
DeFrank, J.S.5
Tang, W.6
-
30
-
-
0028980494
-
p53 controls both the G2/M and the G1 cell cycle checkpoints and mediates reversible growth arrest in human fibroblasts
-
Agarwal M.L., Agarwal A., Taylor W.R., and Stark G.R. p53 controls both the G2/M and the G1 cell cycle checkpoints and mediates reversible growth arrest in human fibroblasts. Proc Natl Acad Sci U S A 92 (1995) 8493-8497
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 8493-8497
-
-
Agarwal, M.L.1
Agarwal, A.2
Taylor, W.R.3
Stark, G.R.4
-
31
-
-
0033961880
-
Constitutive activation of cyclin B1-associated cdc2 kinase overrides p53-mediated G2-M arrest
-
Park M., Chae H.D., Yun J., Jung M., Kim Y.S., Kim S.H., et al. Constitutive activation of cyclin B1-associated cdc2 kinase overrides p53-mediated G2-M arrest. Cancer Res 60 (2000) 542-545
-
(2000)
Cancer Res
, vol.60
, pp. 542-545
-
-
Park, M.1
Chae, H.D.2
Yun, J.3
Jung, M.4
Kim, Y.S.5
Kim, S.H.6
-
32
-
-
0038823604
-
Electroporation and carrier DNA cause p53 activation, cell cycle arrest, and apoptosis
-
Lepik D., Jaks V., Kadaja L., Varv S., and Maimet T. Electroporation and carrier DNA cause p53 activation, cell cycle arrest, and apoptosis. Anal Biochem 318 (2003) 52-59
-
(2003)
Anal Biochem
, vol.318
, pp. 52-59
-
-
Lepik, D.1
Jaks, V.2
Kadaja, L.3
Varv, S.4
Maimet, T.5
-
33
-
-
22044443282
-
Expression profile of an operationally-defined neural stem cell clone
-
Parker M.A., Anderson J.K., Corliss D.A., Abraria V.E., Sidman R.L., Park K.I., et al. Expression profile of an operationally-defined neural stem cell clone. Exp Neurol 194 (2005) 320-332
-
(2005)
Exp Neurol
, vol.194
, pp. 320-332
-
-
Parker, M.A.1
Anderson, J.K.2
Corliss, D.A.3
Abraria, V.E.4
Sidman, R.L.5
Park, K.I.6
-
34
-
-
14644432362
-
Apigenin inhibits VEGF and HIF-1 expression via PI3K/AKT/p70S6K1 and HDM2/p53 pathways
-
Fang J., Xia C., Cao Z., Zheng J.Z., Reed E., and Jiang B.H. Apigenin inhibits VEGF and HIF-1 expression via PI3K/AKT/p70S6K1 and HDM2/p53 pathways. FASEB J 19 (2005) 342-353
-
(2005)
FASEB J
, vol.19
, pp. 342-353
-
-
Fang, J.1
Xia, C.2
Cao, Z.3
Zheng, J.Z.4
Reed, E.5
Jiang, B.H.6
-
35
-
-
34047132303
-
Apigenin inhibits tumor angiogenesis through decreasing HIF-1alpha and VEGF expression
-
Fang J., Zhou Q., Liu L.Z., Xia C., Hu X., Shi X., et al. Apigenin inhibits tumor angiogenesis through decreasing HIF-1alpha and VEGF expression. Carcinogenesis 28 (2007) 858-864
-
(2007)
Carcinogenesis
, vol.28
, pp. 858-864
-
-
Fang, J.1
Zhou, Q.2
Liu, L.Z.3
Xia, C.4
Hu, X.5
Shi, X.6
-
36
-
-
20844448924
-
Human gut microbial degradation of flavonoids: structure-function relationships
-
Simons A.L., Renouf M., Hendrich S., and Murphy P.A. Human gut microbial degradation of flavonoids: structure-function relationships. J Agric Food Chem 53 (2005) 4258-4263
-
(2005)
J Agric Food Chem
, vol.53
, pp. 4258-4263
-
-
Simons, A.L.1
Renouf, M.2
Hendrich, S.3
Murphy, P.A.4
|