Involvement of tumor necrosis factor-α receptor 1 and tumor necrosis factor-related apoptosis-inducing ligand-(TRAIL) receptor-2/DR-5, but not Fas, in graft injury in live-donor liver transplantation

Transplant International

Volumn 17, Issue 10, 2004, Pages 626-633

  Tashiro, Hirotaka ^a   Itamoto, Toshiyuki ^a   Ohdan, Hideki ^a   Arihiro, Kouji ^b   Tateaki, Yuko ^c   Nakahara, Hideki ^a   Ochi, Makoto ^a   Hino, Hiroshi ^a   Mizunuma, Kazuyuki ^a   Hara, Hidetaka ^a   Tokita, Daisuke ^a   Onoe, Takashi ^a   Ishiyama, Kouhei ^a   Mitsuta, Hiroshi ^a   Sugino, Keizou ^a   Asahara, Toshimasa ^a  

^a HIROSHIMA UNIV SCHOOL OF MEDICINE   (Japan)

^b HIROSHIMA UNIVERSITY HOSPITAL   (Japan)

^c HIROSHIMA UNIVERSITY   (Japan)

Author keywords

Apoptosis; Death receptor; Ischemia reperfusion injury; Liver allograft; Necrosis

Indexed keywords

ALANINE; ALANINE AMINOTRANSFERASE; DEATH RECEPTOR 5; FAS LIGAND; TRANSFERASE; TUMOR NECROSIS FACTOR ALPHA RECEPTOR; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND;

ADULT; ALLOGRAFT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DOWN REGULATION; ENZYME BLOOD LEVEL; FEMALE; GRAFT FAILURE; HUMAN; HUMAN TISSUE; IMPLANTATION; LIVER ISCHEMIA; LIVER NECROSIS; LIVER RESECTION; LIVER TRANSPLANTATION; LIVING DONOR; MALE; POSTOPERATIVE CARE; PRIORITY JOURNAL; PROTEIN EXPRESSION; STATISTICAL SIGNIFICANCE;

ANTIGENS, CD95; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CHILD, PRESCHOOL; CHOLECYSTECTOMY; FAS LIGAND PROTEIN; FEMALE; HEPATECTOMY; HUMANS; ISCHEMIA; LIVER; LIVER TRANSPLANTATION; LIVING DONORS; MALE; MEMBRANE GLYCOPROTEINS; NECROSIS; POSTOPERATIVE PERIOD; RECEPTORS, TNF-RELATED APOPTOSIS-INDUCING LIGAND; RECEPTORS, TUMOR NECROSIS FACTOR; TNF-RELATED APOPTOSIS-INDUCING LIGAND; TUMOR NECROSIS FACTOR-ALPHA;

EID: 19944428086     PISSN: 09340874     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00147-004-0762-z     Document Type: Article

References (33)

1. Grace P. Ischemia-reperfusion injury. Br J Surg 1994; 81:637.
2. Serizawa A, Nakamura S, Suzuku S, Baba S, Nakano M. Involvement of platelet-activating factor in cytokine production and neutrophil activation after hepatic ischemia/reperfusion. Hepatology 1996; 23:1656.
3. Mutoy Y, Nouri-Aria KT, Meager A, Alexander GJ, Eddleston AL, Williams R. Enhanced tumor necrosis factor and interleukine-1 in fulminant hepatic failure. Lancet 1998; 8602:72.
4. Bradham CA, Plumpe J, Manns MP, Brenner DA, Trautwein C. Mechanisms of hepatic toxicity: TNF-induced liver injury. Am Phys Soc 1998; G387.
5. Alex B. Lentsch. Inflammatory mechanisms and therapeutic strategies for warm hepatic ischemia/reperfusion injury. Hepatology 2000; 32:169.
6. Faubion WA, Gores GJ. Death receptors in liver biology and pathology. Hepatology 1999; 29:1.
7. Colletti L, Burtch G, Remick D, et al. The production of tumor necrosis factor alpha and the development of a pulmonary capillary injury following hepatic ischemia/reperfusion. Transplantation 1990: 49:268.
8. Colletti L, Remick D, Burtch G, Kunkel S, Strieter R, Campbel D. Role of tumor necrosis factor-alpha in the pathophysiologic alterations after hepatic ischemia/reperfusion injury in the rat. J Clin Invest 1990; 85:1936.
9. Bazzoni F, Beutler B. The tumor necrosis factor ligand and receptor families. N Engl J Med 1996; 334:1717.
10. Ashkenazi A, Dixit V. Death receptors: signaling and modulation. Science 1998; 281:13058.
11. Ogasawara J, Watanabe-Fukunaga R, Adachi M, et al. Lethal effect of the anti-Fas antibody in mice. Nature 1993; 364:806.
12. Mochizuki K, Hayashi N, Hiramatsu N, et al. Fas antigen expression in liver tissues of patients with chronic hepatitis B. J Hepatol 1996; 24:1.
13. Thomas S Griffith. TRAIL: a molecule with multiple receptors and control mechanisms. Curr Opin Immunol 1998; 10:559.
14. Walczak H, Miller RE, Ariail K, et al. Tumoricidal activity of tumor necrosis-factor-related apoptosis-inducing ligand in vivo. Nat Med 1999; 5:157.
15. Jo M, Kim TH, Seol DW, et al. Apoptosis induced in normal human hepatocytes by tumor necrosis factor-related apoptosis-inducing ligand. Nat Med 2000; 6:564.
16. Gores GJ, Kaufmann SH. Is TRAIL hepatotoxic? Hepatology 2001; 34:3.
17. Pan G, Orourke K, Chinnaiyan AM, et al. The receptor for the cytotoxic ligand TRAIL. Science 1997; 276:111.
18. Sheridan JP, Marsters SA, Pitti RM, Gurney A, Skubatch M, Baldwin D, Ramakrishnan L, Gray Cl, et al. Control of TRAIL-induced apoptosis by a family of signaling and decoy receptors. Science 1997; 277:818.
19. Chaudhary PM, Eby M, Jasmin A, Bookwalter A, Murray J, Hood L. Death receptor 5, a new member of the TNFR family, and DR4 induce FADD-dependent apoptosis and activate the NF-kappaB pathway. Immunity 1997; 7:821.
20. Chomczynski P, Sacchi A. Single-step method of RNA isolation by acid guanidium thiocyanate-chloroform extraction. Anal Biochem 1987; 162:156.
21. Gao W, Bentley R, madden JF, Clavien PA. Apoptosis of sinusoidal endothelial cells is a critical mechanism of preservation injury in rat liver transplantation. Hepatology 1998; 27:1652.
22. Clavien PA. Sinusoidal endothelial cell injury during hepatic preservation and reperfusion. Hepatology 1998; 28:281.
23. Kohli V, Seizner M, Madden J, Bentley RC, Clavien PA. Endothelial cell and hepatocyte deaths occur by apoptosis after ischemia-reperfusion injury in the rat liver. Transplantation 1999; 67:1099.
24. Gujral J, Bucci T, Farhood A, Jaeschke H. Mechanism of cell death during warm hepatic ischemia-reperfusion in rats: apoptosis or necrosis? Hepatology 2001; 33:397.
25. Clavien PA. Protective effects of ischemie preconditioning for liver resection performed under inflow occlusion in humans. Ann Surg 2000; 232:155.
26. Rudiger HA, Clavien PA. Tumor necrosis factor α, but not Fas, mediates hepatocellular apoptosis in the murine ischemic liver. Gastroenterology 2002; 122:202.
27. Iwata S, Taki Y, Kawai Y, Kanai M, Takabayashi A. Mitochondrial membrane potential is reduced in peripheral natural killer cells following partial hepatectomy. Immunol Lett 2002; 82:225.
28. Vujanovic NL, Polimeno L, Azzarone A, et al. Changes of liver-resident NK cells during liver regeneration in rats. J Immunol 1995; 154:6324.
29. Matsushita T, Ando K, Kimura K, et al. IL-12 induces specific cytotoxicity against regenerating hepatocytes in vivo. Int Immunol 1999; 11:657.
30. Zhang HG, Xie J, Xu L, et al. Hepatic DR5 induces apoptosis and limits adenovirus gene therapy products expression in the liver. J Virol 2002; 76:5692.
31. Ichikawa K, Liu W, Zhao L, et al. Tumoricidal activity of a novel anti-human DR5 monoclonal antibody without hepatocyte cytotoxicity. Nat Med 2001; 7:954.
32. Higuchi H, Bronk SF, Taniai M, Canbay A, Gores GJ. Cholestasis increases tumor necrosis factor-related apoptosis- inducing ligand (TRAIL)-R2/DR5 expression and sensitizes the liver TRAIL-mediated cytotoxicity. J Pharmacol Exp Ther 2002; 303:461.
33. Guicciardi ME, Miyoshi H, Bronk SF, Gores GJ. Cathepsin B. Knockout mice are resistant to tumor necrosis factor-a-mediated hepatocyte apoptosis and liver injury: implications for therapeutic applications. Am J Path 2001; 159:2045.