Solanum incanum extract (SR-T100) induces human cutaneous squamous cell carcinoma apoptosis through modulating tumor necrosis factor receptor signaling pathway

Journal of Dermatological Science

Volumn 63, Issue 2, 2011, Pages 83-92

  Wu, Chin Han ^a   Liang, Chia Hua ^b   Shiu, Li Yen ^c   Chang, Li Ching ^d   Lin, Tsai Shiuan ^a   Lan, Cheng Che Eric ^e   Tsai, Jui Chen ^a   Wong, Tak Wah ^a   Wei, Kai Jhe ^a   Lin, Tzu Kai ^a   Chang, Nan Shan ^a   Sheu, Hamm Ming ^a  

^a NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^b CHIA NAN UNIVERSITY OF PHARMACY AND SCIENCE   (Taiwan)

^c CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

^d I SHOU UNIVERSITY   (Taiwan)

^e KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Actinic keratosis; Apoptosis; Solamargine; Solanum incanum; Squamous cell carcinoma

Indexed keywords

ANTINEOPLASTIC AGENT; BETA ACTIN; BROXURIDINE; CASPASE 3; CYCLINE; CYTOCHROME C; FAS ASSOCIATED DEATH DOMAIN PROTEIN; FAS LIGAND; FLUOROURACIL; PLANT EXTRACT; PROTEIN BAX; PROTEIN BCL XL; SOLAMARGINE; SR T 100; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR 1; TUMOR NECROSIS FACTOR RECEPTOR 2; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED DEATH DOMAIN PROTEIN; UNCLASSIFIED DRUG;

ACTINIC KERATOSIS; AGED; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; APPLICATION SITE EROSION; APPLICATION SITE PAIN; APPLICATION SITE REACTION; APPLICATION SITE STINGING; ARTICLE; CANCER INHIBITION; CELL PROLIFERATION; CLINICAL ARTICLE; CLINICAL TRIAL; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA SYNTHESIS INHIBITION; DRUG EFFICACY; DRUG MECHANISM; DRUG SAFETY; FEMALE; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PAPILLOMA; PRECANCER; PRIORITY JOURNAL; PROTEIN EXPRESSION; PRURITUS; SKIN CARCINOMA; SOLANUM; SOLANUM INCANUM; SQUAMOUS CELL CARCINOMA; ULTRAVIOLET B RADIATION; XEROSIS;

AGED; AGED, 80 AND OVER; ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CARCINOMA, SQUAMOUS CELL; CELL LINE, TUMOR; CYTOCHROMES C; FEMALE; HUMANS; MALE; MICE; MICE, HAIRLESS; MITOCHONDRIA; PAPILLOMA; PLANT EXTRACTS; RECEPTORS, TUMOR NECROSIS FACTOR; SIGNAL TRANSDUCTION; SKIN NEOPLASMS; SOLANACEOUS ALKALOIDS; SOLANUM; ULTRAVIOLET RAYS;

EID: 79959844911     PISSN: 09231811     EISSN: 1873569X     Source Type: Journal    
DOI: 10.1016/j.jdermsci.2011.04.003     Document Type: Article

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