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Volumn 11, Issue 9, 2012, Pages 1757-1764

From oncogene to tumor suppressor: The dual role of Myc in leukemia

Author keywords

c Myc; Chromatin; Gene regulation; Leukemia; Max; RAR; Retinoic acid; Transcription

Indexed keywords

ARAC PROTEIN; B LYMPHOCYTE INDUCED MATURATION PROTEIN 1; BETA CATENIN; CELL NUCLEUS RECEPTOR; INTEGRIN; MITOGEN ACTIVATED PROTEIN KINASE; MYC PROTEIN; MYOCYTE ENHANCER FACTOR 2; MYOD PROTEIN; NERVE CELL ADHESION MOLECULE; P21 ACTIVATED KINASE 2; RAC PROTEIN; SERUM RESPONSE FACTOR; TRANSCRIPTOME;

EID: 84860744605     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.19883     Document Type: Review
Times cited : (41)

References (92)
  • 1
    • 3042781552 scopus 로고    scopus 로고
    • Analysis of genomic targets reveals complex functions of MYC
    • PMID:15229481
    • Patel JH, Loboda AP, Showe MK, Showe LC, McMahon SB. Analysis of genomic targets reveals complex functions of MYC. Nat Rev Cancer 2004; 4:562-8; PMID:15229481; http://dx.doi.org/10.1038/nrc1393.
    • (2004) Nat Rev Cancer , vol.4 , pp. 562-568
    • Patel, J.H.1    Loboda, A.P.2    Showe, M.K.3    Showe, L.C.4    McMahon, S.B.5
  • 2
    • 0025608909 scopus 로고
    • Sequence-specific DNA binding by the c-Myc protein
    • PMID:2251503
    • Blackwell TK, Kretzner L, Blackwood EM, Eisenman RN, Weintraub H. Sequence-specific DNA binding by the c-Myc protein. Science 1990; 250:1149-51; PMID:2251503; http://dx.doi.org/10.1126/science.2251503.
    • (1990) Science , vol.250 , pp. 1149-1151
    • Blackwell, T.K.1    Kretzner, L.2    Blackwood, E.M.3    Eisenman, R.N.4    Weintraub, H.5
  • 3
    • 0025763419 scopus 로고
    • Max: A helixloophelix zipper protein that forms a sequence-specific DNA-binding complex with Myc
    • PMID:2006410
    • Blackwood EM, Eisenman RN. Max: a helixloophelix zipper protein that forms a sequence-specific DNA-binding complex with Myc. Science 1991; 251:1211-7; PMID:2006410; http://dx.doi.org/10.1126/science.2006410.
    • (1991) Science , vol.251 , pp. 1211-1217
    • Blackwood, E.M.1    Eisenman, R.N.2
  • 5
    • 0032905924 scopus 로고    scopus 로고
    • c-Myc target genes involved in cell growth, apoptosis and metabolism
    • PMID:9858526
    • Dang CV. c-Myc target genes involved in cell growth, apoptosis and metabolism. Mol Cell Biol 1999; 19:1-11; PMID:9858526.
    • (1999) Mol Cell Biol , vol.19 , pp. 1-11
    • Dang, C.V.1
  • 6
    • 0033611644 scopus 로고    scopus 로고
    • Control of cell proliferation by Myc family genes
    • PMID:10102563
    • Eilers M. Control of cell proliferation by Myc family genes. Mol Cells 1999; 9:1-6; PMID:10102563.
    • (1999) Mol Cells , vol.9 , pp. 1-6
    • Eilers, M.1
  • 9
    • 0025201927 scopus 로고
    • Downregulation of LFA-1 adhesion receptors by C-myc oncogene in human B lymphoblastoid cells
    • PMID:2237417
    • Inghirami G, Grignani F, Sternas L, Lombardi L, Knowles DM, Dalla-Favera R. Downregulation of LFA-1 adhesion receptors by C-myc oncogene in human B lymphoblastoid cells. Science 1990; 250:682-6; PMID:2237417; http://dx.doi.org/10.1126/science.2237417.
    • (1990) Science , vol.250 , pp. 682-686
    • Inghirami, G.1    Grignani, F.2    Sternas, L.3    Lombardi, L.4    Knowles, D.M.5    Dalla-Favera, R.6
  • 10
    • 0037126303 scopus 로고    scopus 로고
    • Myc suppression of the p21(Cip1) Cdk inhibitor influences the outcome of the p53 response to DNA damage
    • PMID:12384701
    • Seoane J, Le HV, Massagué J. Myc suppression of the p21(Cip1) Cdk inhibitor influences the outcome of the p53 response to DNA damage. Nature 2002; 419:729-34; PMID:12384701; http://dx.doi.org/10.1038/nature01119.
    • (2002) Nature , vol.419 , pp. 729-734
    • Seoane, J.1    Le, H.V.2    Massagué, J.3
  • 11
    • 18644371442 scopus 로고    scopus 로고
    • Negative regulation of the mammalian UV response by Myc through association with Miz-1
    • PMID:12408820
    • Herold S, Wanzel M, Beuger V, Frohme C, Beul D, Hillukkala T, et al. Negative regulation of the mammalian UV response by Myc through association with Miz-1. Mol Cell 2002; 10:509-21; PMID:12408820; http://dx.doi.org/10.1016/ S1097-2765(02)00633-0.
    • (2002) Mol Cell , vol.10 , pp. 509-521
    • Herold, S.1    Wanzel, M.2    Beuger, V.3    Frohme, C.4    Beul, D.5    Hillukkala, T.6
  • 12
    • 0035967099 scopus 로고    scopus 로고
    • Repression of transcription of the p27(Kip1) cyclin-dependent kinase inhibitor gene by c-Myc
    • PMID:11313917
    • Yang W, Shen J, Wu M, Arsura M, FitzGerald M, Suldan Z, et al. Repression of transcription of the p27(Kip1) cyclin-dependent kinase inhibitor gene by c-Myc. Oncogene 2001; 20:1688-702; PMID:11313917; http://dx.doi.org/10.1038/sj. onc.1204245.
    • (2001) Oncogene , vol.20 , pp. 1688-1702
    • Yang, W.1    Shen, J.2    Wu, M.3    Arsura, M.4    FitzGerald, M.5    Suldan, Z.6
  • 13
    • 0037108268 scopus 로고    scopus 로고
    • N-myc is essential during neurogenesis for the rapid expansion of progenitor cell populations and the inhibition of neuronal differentiation
    • PMID:12381668
    • Knoepfler PS, Cheng PF, Eisenman RN. N-myc is essential during neurogenesis for the rapid expansion of progenitor cell populations and the inhibition of neuronal differentiation. Genes Dev 2002; 16:2699-712; PMID:12381668; http://dx.doi.org/10.1101/gad.1021202.
    • (2002) Genes Dev , vol.16 , pp. 2699-2712
    • Knoepfler, P.S.1    Cheng, P.F.2    Eisenman, R.N.3
  • 14
    • 0035901594 scopus 로고    scopus 로고
    • c-Myc activation in transgenic mouse epidermis results in mobilization of stem cells and differentiation of their progeny
    • PMID:11369200
    • Arnold I, Watt FM. c-Myc activation in transgenic mouse epidermis results in mobilization of stem cells and differentiation of their progeny. Curr Biol 2001; 11:558-68; PMID:11369200; http://dx.doi.org/10.1016/S0960-9822(01)00154-3.
    • (2001) Curr Biol , vol.11 , pp. 558-568
    • Arnold, I.1    Watt, F.M.2
  • 15
    • 0034978920 scopus 로고    scopus 로고
    • Deregulated expression of c-Myc depletes epidermal stem cells
    • PMID:11381265
    • Waikel RL, Kawachi Y, Waikel PA, Wang XJ, Roop DR. Deregulated expression of c-Myc depletes epidermal stem cells. Nat Genet 2001; 28:165-8; PMID:11381265; http://dx.doi.org/10.1038/88889.
    • (2001) Nat Genet , vol.28 , pp. 165-168
    • Waikel, R.L.1    Kawachi, Y.2    Waikel, P.A.3    Wang, X.J.4    Roop, D.R.5
  • 16
    • 39749124274 scopus 로고    scopus 로고
    • MYC in mammalian epidermis: How can an oncogene stimulate differentiation?
    • PMID:18292777
    • Watt FM, Frye M, Benitah SA. MYC in mammalian epidermis: how can an oncogene stimulate differentiation? Nat Rev Cancer 2008; 8:234-42; PMID:18292777; http://dx.doi.org/10.1038/nrc2328.
    • (2008) Nat Rev Cancer , vol.8 , pp. 234-242
    • Watt, F.M.1    Frye, M.2    Benitah, S.A.3
  • 17
    • 74849135477 scopus 로고    scopus 로고
    • Myc's secret life without Max
    • PMID:19887915
    • Gallant P, Steiger D. Myc's secret life without Max. Cell Cycle 2009; 8:3848-53; PMID:19887915; http://dx.doi.org/10.4161/cc.8.23.10088.
    • (2009) Cell Cycle , vol.8 , pp. 3848-3853
    • Gallant, P.1    Steiger, D.2
  • 18
    • 50449096026 scopus 로고    scopus 로고
    • Max-independent functions of Myc in Drosophila melanogaster
    • PMID:19165923
    • Steiger D, Furrer M, Schwinkendorf D, Gallant P. Max-independent functions of Myc in Drosophila melanogaster. Nat Genet 2008; 40:1084-91; PMID:19165923; http://dx.doi.org/10.1038/ng.178.
    • (2008) Nat Genet , vol.40 , pp. 1084-1091
    • Steiger, D.1    Furrer, M.2    Schwinkendorf, D.3    Gallant, P.4
  • 19
    • 23144464363 scopus 로고    scopus 로고
    • Transcriptional regulation and transformation by Myc proteins
    • PMID:16064138
    • Adhikary S, Eilers M. Transcriptional regulation and transformation by Myc proteins. Nat Rev Mol Cell Biol 2005; 6:635-45; PMID:16064138; http:// dx.doi.org/10.1038/nrm1703.
    • (2005) Nat Rev Mol Cell Biol , vol.6 , pp. 635-645
    • Adhikary, S.1    Eilers, M.2
  • 20
    • 0027425699 scopus 로고
    • Direct role for Myc in transcription initiation mediated by interactions with TFII-I
    • PMID:8377829
    • Roy AL, Carruthers C, Gutjahr T, Roeder RG. Direct role for Myc in transcription initiation mediated by interactions with TFII-I. Nature 1993; 365:359-61; PMID:8377829; http://dx.doi.org/10.1038/365359a0.
    • (1993) Nature , vol.365 , pp. 359-361
    • Roy, A.L.1    Carruthers, C.2    Gutjahr, T.3    Roeder, R.G.4
  • 21
    • 0027745645 scopus 로고
    • Inhibition of transcriptional regulator Yin-Yang-1 by association with c-Myc
    • PMID:8266081
    • Shrivastava A, Saleque S, Kalpana GV, Artandi S, Goff SP, Calame K. Inhibition of transcriptional regulator Yin-Yang-1 by association with c-Myc. Science 1993; 262:1889-92; PMID:8266081; http:// dx.doi.org/10.1126/science. 8266081.
    • (1993) Science , vol.262 , pp. 1889-1892
    • Shrivastava, A.1    Saleque, S.2    Kalpana, G.V.3    Artandi, S.4    Goff, S.P.5    Calame, K.6
  • 22
    • 0035836706 scopus 로고    scopus 로고
    • Myc represses the p21(WAF1/ CIP1) promoter and interacts with Sp1/Sp3
    • PMID:11274368
    • Gartel AL, Ye X, Goufman E, Shianov P, Hay N, Najmabadi F, et al. Myc represses the p21(WAF1/ CIP1) promoter and interacts with Sp1/Sp3. Proc Natl Acad Sci USA 2001; 98:4510-5; PMID:11274368; http://dx.doi.org/10.1073/pnas. 081074898.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 4510-4515
    • Gartel, A.L.1    Ye, X.2    Goufman, E.3    Shianov, P.4    Hay, N.5    Najmabadi, F.6
  • 23
    • 0035014553 scopus 로고    scopus 로고
    • Mechanism for the transcriptional repression by c-Myc on PDGF beta-receptor
    • PMID:11282029
    • Izumi H, Molander C, Penn LZ, Ishisaki A, Kohno K, Funa K. Mechanism for the transcriptional repression by c-Myc on PDGF beta-receptor. J Cell Sci 2001; 114:1533-44; PMID:11282029.
    • (2001) J Cell Sci , vol.114 , pp. 1533-1544
    • Izumi, H.1    Molander, C.2    Penn, L.Z.3    Ishisaki, A.4    Kohno, K.5    Funa, K.6
  • 24
    • 0842347423 scopus 로고    scopus 로고
    • Negative control of the Myc protein by the stress-responsive kinase Pak2
    • PMID:14749374
    • Huang Z, Traugh JA, Bishop JM. Negative control of the Myc protein by the stress-responsive kinase Pak2. Mol Cell Biol 2004; 24:1582-94; PMID:14749374; http://dx.doi.org/10.1128/MCB.24.4.1582-94.2004.
    • (2004) Mol Cell Biol , vol.24 , pp. 1582-1594
    • Huang, Z.1    Traugh, J.A.2    Bishop, J.M.3
  • 25
    • 0029132202 scopus 로고
    • Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor
    • PMID:7566114
    • Hörlein AJ, Näär AM, Heinzel T, Torchia J, Gloss B, Kurokawa R, et al. Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor. Nature 1995; 377:397-404; PMID:7566114; http://dx.doi.org/10.1038/377397a0.
    • (1995) Nature , vol.377 , pp. 397-404
    • Hörlein, A.J.1    Näär, A.M.2    Heinzel, T.3    Torchia, J.4    Gloss, B.5    Kurokawa, R.6
  • 26
    • 0029097233 scopus 로고
    • A transcriptional co-repressor that interacts with nuclear hormone receptors
    • PMID:7566127
    • Chen JD, Evans RM. A transcriptional co-repressor that interacts with nuclear hormone receptors. Nature 1995; 377:454-7; PMID:7566127; http://dx.doi.org/10.1038/377454a0.
    • (1995) Nature , vol.377 , pp. 454-457
    • Chen, J.D.1    Evans, R.M.2
  • 27
    • 0242587820 scopus 로고    scopus 로고
    • A CBP integrator complex mediates transcriptional activation and AP-1 inhibition by nuclear receptors
    • PMID:8616895
    • Kamei Y, Xu L, Heinzel T, Torchia J, Kurokawa R, Gloss B, et al. A CBP integrator complex mediates transcriptional activation and AP-1 inhibition by nuclear receptors. Cell 1996; 85:403-14; PMID:8616895; http://dx.doi.org/10. 1016/S0092-8674(00)81118-6.
    • (1996) Cell , vol.85 , pp. 403-414
    • Kamei, Y.1    Xu, L.2    Heinzel, T.3    Torchia, J.4    Kurokawa, R.5    Gloss, B.6
  • 29
    • 17744413444 scopus 로고    scopus 로고
    • A complex containing N-CoR, mSin3 and histone deacetylase mediates transcriptional repression
    • PMID:9139820
    • Heinzel T, Lavinsky RM, Mullen TM, Söderstrom M, Laherty CD, Torchia J, et al. A complex containing N-CoR, mSin3 and histone deacetylase mediates transcriptional repression. Nature 1997; 387:43-8; PMID:9139820; http://dx.doi.org/10.1038/387043a0.
    • (1997) Nature , vol.387 , pp. 43-48
    • Heinzel, T.1    Lavinsky, R.M.2    Mullen, T.M.3    Söderstrom, M.4    Laherty, C.D.5    Torchia, J.6
  • 30
    • 45549095542 scopus 로고    scopus 로고
    • Myc-mediated transcriptional repression by recruitment of histone deacetylase
    • PMID:18483244
    • Kurland JF, Tansey WP. Myc-mediated transcriptional repression by recruitment of histone deacetylase. Cancer Res 2008; 68:3624-9; PMID:18483244; http://dx.doi.org/10.1158/0008-5472.CAN-07-6552.
    • (2008) Cancer Res , vol.68 , pp. 3624-3629
    • Kurland, J.F.1    Tansey, W.P.2
  • 31
    • 0038110044 scopus 로고    scopus 로고
    • Stimulation of c-MYC transcriptional activity and acetylation by recruitment of the cofactor CBP
    • PMID:12776737
    • Vervoorts J, Lüscher-Firzlaff JM, Rottmann S, Lilischkis R, Walsemann G, Dohmann K, et al. Stimulation of c-MYC transcriptional activity and acetylation by recruitment of the cofactor CBP. EMBO Rep 2003; 4:484-90; PMID:12776737; http://dx.doi.org/10.1038/sj.embor.embor821.
    • (2003) EMBO Rep , vol.4 , pp. 484-490
    • Vervoorts, J.1    Lüscher-Firzlaff, J.M.2    Rottmann, S.3    Lilischkis, R.4    Walsemann, G.5    Dohmann, K.6
  • 32
    • 0027219913 scopus 로고
    • Retinoid acid supports granulocytic but not erythroid differentiation of myeloid progenitors in normal bone marrow cells
    • PMID:8350615
    • Gratas C, Menot ML, Dresch C, Chomienne C. Retinoid acid supports granulocytic but not erythroid differentiation of myeloid progenitors in normal bone marrow cells. Leukemia 1993; 7:1156-62; PMID:8350615.
    • (1993) Leukemia , vol.7 , pp. 1156-1162
    • Gratas, C.1    Menot, M.L.2    Dresch, C.3    Chomienne, C.4
  • 33
    • 77952576753 scopus 로고    scopus 로고
    • The Yin and Yang functions of the Myc oncoprotein in cancer development and as targets for therapy
    • PMID:20382143
    • Larsson LG, Henriksson MA. The Yin and Yang functions of the Myc oncoprotein in cancer development and as targets for therapy. Exp Cell Res 2010; 316:1429-37; PMID:20382143; http://dx.doi.org/10.1016/j.yexcr.2010.03.025.
    • (2010) Exp Cell Res , vol.316 , pp. 1429-1437
    • Larsson, L.G.1    Henriksson, M.A.2
  • 34
    • 65949119311 scopus 로고    scopus 로고
    • Inhibition of cell differentiation: A critical mechanism for MYC-mediated carcinogenesis?
    • PMID:19282668
    • Leon J, Ferrandiz N, Acosta JC, Delgado MD. Inhibition of cell differentiation: a critical mechanism for MYC-mediated carcinogenesis? Cell Cycle 2009; 8:1148-57; PMID:19282668; http://dx.doi.org/10.4161/cc.8.8.8126.
    • (2009) Cell Cycle , vol.8 , pp. 1148-1157
    • Leon, J.1    Ferrandiz, N.2    Acosta, J.C.3    Delgado, M.D.4
  • 35
    • 84856185118 scopus 로고    scopus 로고
    • E-box-independent regulation of transcription and differentiation by MYC
    • PMID:22020439
    • Uribesalgo I, Buschbeck M, Gutiérrez A, Teichmann S, Demajo S, Kuebler B, et al. E-box-independent regulation of transcription and differentiation by MYC. Nat Cell Biol 2011; 13:1443-9; PMID:22020439; http://dx.doi.org/10.1038/ncb2355.
    • (2011) Nat Cell Biol , vol.13 , pp. 1443-1449
    • Uribesalgo, I.1    Buschbeck, M.2    Gutiérrez, A.3    Teichmann, S.4    Demajo, S.5    Kuebler, B.6
  • 36
    • 10044276927 scopus 로고    scopus 로고
    • c-Myc-mediated expression of nucleophosmin/ B23 decreases during retinoic acid-induced differentiation of human leukemia HL-60 cells
    • PMID:15589822
    • Yung BY. c-Myc-mediated expression of nucleophosmin/ B23 decreases during retinoic acid-induced differentiation of human leukemia HL-60 cells. FEBS Lett 2004; 578:211-6; PMID:15589822; http:// dx.doi.org/10.1016/j.febslet.2004.08. 089.
    • (2004) FEBS Lett , vol.578 , pp. 211-216
    • Yung, B.Y.1
  • 37
    • 0036106096 scopus 로고    scopus 로고
    • Interaction between p21-activated protein kinase and Rac during differentiation of HL-60 human promyelocytic leukemia cell induced by all-trans-retinoic acid
    • PMID:12027902
    • Nisimoto Y, Ogawa H. Interaction between p21-activated protein kinase and Rac during differentiation of HL-60 human promyelocytic leukemia cell induced by all-trans-retinoic acid. Eur J Biochem 2002; 269:2622-9; PMID:12027902; http://dx.doi.org/10.1046/j.1432-033.2002.02939.x.
    • (2002) Eur J Biochem , vol.269 , pp. 2622-2629
    • Nisimoto, Y.1    Ogawa, H.2
  • 38
    • 79958735965 scopus 로고    scopus 로고
    • Actomyosin-mediated cellular tension drives increased tissue stiffness and β-catenin activation to induce epidermal hyperplasia and tumor growth
    • PMID:21665151
    • Samuel MS, Lopez JI, McGhee EJ, Croft DR, Strachan D, Timpson P, et al. Actomyosin-mediated cellular tension drives increased tissue stiffness and β-catenin activation to induce epidermal hyperplasia and tumor growth. Cancer Cell 2011; 19:776-91; PMID:21665151; http://dx.doi.org/10.1016/j.ccr. 2011.05.008.
    • (2011) Cancer Cell , vol.19 , pp. 776-791
    • Samuel, M.S.1    Lopez, J.I.2    McGhee, E.J.3    Croft, D.R.4    Strachan, D.5    Timpson, P.6
  • 39
    • 0038737042 scopus 로고    scopus 로고
    • Actin dynamics control SRF activity by regulation of its coactivator MAL
    • PMID:12732141
    • Miralles F, Posern G, Zaromytidou AI, Treisman R. Actin dynamics control SRF activity by regulation of its coactivator MAL. Cell 2003; 113:329-42; PMID:12732141; http://dx.doi.org/10.1016/S0092-8674(03)00278-2.
    • (2003) Cell , vol.113 , pp. 329-342
    • Miralles, F.1    Posern, G.2    Zaromytidou, A.I.3    Treisman, R.4
  • 40
    • 34250849566 scopus 로고    scopus 로고
    • Nuclear actin regulates dynamic subcellular localization and activity of the SRF cofactor MAL
    • PMID:17588931
    • Vartiainen MK, Guettler S, Larijani B, Treisman R. Nuclear actin regulates dynamic subcellular localization and activity of the SRF cofactor MAL. Science 2007; 316:1749-52; PMID:17588931; http://dx.doi.org/10.1126/science. 1141084.
    • (2007) Science , vol.316 , pp. 1749-1752
    • Vartiainen, M.K.1    Guettler, S.2    Larijani, B.3    Treisman, R.4
  • 41
    • 61849140657 scopus 로고    scopus 로고
    • Myocardin-related transcription factors and SRF are required for cytoskeletal dynamics and experimental metastasis
    • PMID:19198601
    • Medjkane S, Perez-Sanchez C, Gaggioli C, Sahai E, Treisman R. Myocardin-related transcription factors and SRF are required for cytoskeletal dynamics and experimental metastasis. Nat Cell Biol 2009; 11:257-68; PMID:19198601; http://dx.doi.org/10.1038/ncb1833.
    • (2009) Nat Cell Biol , vol.11 , pp. 257-268
    • Medjkane, S.1    Perez-Sanchez, C.2    Gaggioli, C.3    Sahai, E.4    Treisman, R.5
  • 42
    • 77954243855 scopus 로고    scopus 로고
    • Actin and serum response factor transduce physical cues from the microenvironment to regulate epidermal stem cell fate decisions
    • PMID:20581838
    • Connelly JT, Gautrot JE, Trappmann B, Tan DW, Donati G, Huck WT, et al. Actin and serum response factor transduce physical cues from the microenvironment to regulate epidermal stem cell fate decisions. Nat Cell Biol 2010; 12:711-8; PMID:20581838; http://dx.doi.org/10.1038/ncb2074.
    • (2010) Nat Cell Biol , vol.12 , pp. 711-718
    • Connelly, J.T.1    Gautrot, J.E.2    Trappmann, B.3    Tan, D.W.4    Donati, G.5    Huck, W.T.6
  • 43
    • 80355143465 scopus 로고    scopus 로고
    • Shape-induced terminal differentiation of human epidermal stem cells requires p38 and is regulated by histone acetylation
    • PMID:22073300
    • Connelly JT, Mishra A, Gautrot JE, Watt FM. Shape-induced terminal differentiation of human epidermal stem cells requires p38 and is regulated by histone acetylation. PLoS One 2011; 6:27259; PMID:22073300; http://dx.doi.org/ 10.1371/journal.pone.0027259.
    • (2011) PLoS One , vol.6 , pp. 27259
    • Connelly, J.T.1    Mishra, A.2    Gautrot, J.E.3    Watt, F.M.4
  • 44
    • 0033615641 scopus 로고    scopus 로고
    • p21-activated protein kinase gamma-PAK is activated by ionizing radiation and other DNA-damaging agents. Similarities and differences to alpha-PAK
    • PMID:10531298
    • Roig J, Traugh JA. p21-activated protein kinase gamma-PAK is activated by ionizing radiation and other DNA-damaging agents. Similarities and differences to alpha-PAK. J Biol Chem 1999; 274:31119-22; PMID:10531298; http://dx.doi.org/10.1074/jbc.274.44.31119.
    • (1999) J Biol Chem , vol.274 , pp. 31119-31122
    • Roig, J.1    Traugh, J.A.2
  • 45
    • 0034595708 scopus 로고    scopus 로고
    • p21-activated protein kinase gamma-PAK is translocated and activated in response to hyperosmolarity. Implication of Cdc42 and phosphoinositide-3-kinase in a two-step mechanism for gamma-PAK activation
    • PMID:10748040
    • Roig J, Huang Z, Lytle C, Traugh JA. p21-activated protein kinase gamma-PAK is translocated and activated in response to hyperosmolarity. Implication of Cdc42 and phosphoinositide-3-kinase in a two-step mechanism for gamma-PAK activation. J Biol Chem 2000; 275:16933-40; PMID:10748040; http:// dx.doi.org/10.1074/jbc.M001627200.
    • (2000) J Biol Chem , vol.275 , pp. 16933-16940
    • Roig, J.1    Huang, Z.2    Lytle, C.3    Traugh, J.A.4
  • 46
    • 0035234730 scopus 로고    scopus 로고
    • Cytostatic p21 G protein-activated protein kinase gamma-PAK
    • PMID:11345898
    • Roig J, Traugh JA. Cytostatic p21 G protein-activated protein kinase gamma-PAK. Vitam Horm 2001; 62:167-98; PMID:11345898; http://dx.doi.org/10.1016/ S0083-6729(01)62004-1.
    • (2001) Vitam Horm , vol.62 , pp. 167-198
    • Roig, J.1    Traugh, J.A.2
  • 47
    • 0034213138 scopus 로고    scopus 로고
    • p38 MAP kinases: Beyond the stress response
    • PMID:10838561
    • Nebreda AR, Porras A. p38 MAP kinases: beyond the stress response. Trends Biochem Sci 2000; 25:257-60; PMID:10838561; http://dx.doi.org/10.1016/S0968- 0004(00)01595-4.
    • (2000) Trends Biochem Sci , vol.25 , pp. 257-260
    • Nebreda, A.R.1    Porras, A.2
  • 48
    • 70349975711 scopus 로고    scopus 로고
    • JAK2 phosphorylates histone H3Y41 and excludes HP1alpha from chromatin
    • PMID:19783980
    • Dawson MA, Bannister AJ, Göttgens B, Foster SD, Bartke T, Green AR, et al. JAK2 phosphorylates histone H3Y41 and excludes HP1alpha from chromatin. Nature 2009; 461:819-22; PMID:19783980; http://dx.doi.org/10.1038/nature08448.
    • (2009) Nature , vol.461 , pp. 819-822
    • Dawson, M.A.1    Bannister, A.J.2    Göttgens, B.3    Foster, S.D.4    Bartke, T.5    Green, A.R.6
  • 49
    • 0035168692 scopus 로고    scopus 로고
    • Transcriptional induction of MKP-1 in response to stress is associated with histone H3 phosphorylation-acetylation
    • PMID:11689710
    • Li J, Gorospe M, Hutter D, Barnes J, Keyse SM, Liu Y. Transcriptional induction of MKP-1 in response to stress is associated with histone H3 phosphorylation-acetylation. Mol Cell Biol 2001; 21:8213-24; PMID:11689710; http://dx.doi.org/10.1128/MCB.21.23.8213-24.2001.
    • (2001) Mol Cell Biol , vol.21 , pp. 8213-8224
    • Li, J.1    Gorospe, M.2    Hutter, D.3    Barnes, J.4    Keyse, S.M.5    Liu, Y.6
  • 50
    • 0038182524 scopus 로고    scopus 로고
    • MSK2 and MSK1 mediate the mitogen- and stress-induced phosphorylation of histone H3 and HMG-14
    • PMID:12773393
    • Soloaga A, Thomson S, Wiggin GR, Rampersaud N, Dyson MH, Hazzalin CA, et al. MSK2 and MSK1 mediate the mitogen- and stress-induced phosphorylation of histone H3 and HMG-14. EMBO J 2003; 22:2788-97; PMID:12773393; http://dx.doi.org/10.1093/emboj/cdg273.
    • (2003) EMBO J , vol.22 , pp. 2788-2797
    • Soloaga, A.1    Thomson, S.2    Wiggin, G.R.3    Rampersaud, N.4    Dyson, M.H.5    Hazzalin, C.A.6
  • 51
    • 3042763342 scopus 로고    scopus 로고
    • p38 pathway targets SWI-SNF chromatin-remodeling complex to muscle-specific loci
    • PMID:15208625
    • Simone C, Forcales SV, Hill DA, Imbalzano AN, Latella L, Puri PL. p38 pathway targets SWI-SNF chromatin-remodeling complex to muscle-specific loci. Nat Genet 2004; 36:738-43; PMID:15208625; http://dx.doi.org/10.1038/ng1378.
    • (2004) Nat Genet , vol.36 , pp. 738-743
    • Simone, C.1    Forcales, S.V.2    Hill, D.A.3    Imbalzano, A.N.4    Latella, L.5    Puri, P.L.6
  • 52
    • 16244392084 scopus 로고    scopus 로고
    • Epigenetic histone modification and cardiovascular lineage programming in mouse embryonic stem cells exposed to laminar shear stress
    • PMID:15705964
    • Illi B, Scopece A, Nanni S, Farsetti A, Morgante L, Biglioli P, et al. Epigenetic histone modification and cardiovascular lineage programming in mouse embryonic stem cells exposed to laminar shear stress. Circ Res 2005; 96:501-8; PMID:15705964; http:// dx.doi.org/10.1161/01.RES.0000159181.06379.63.
    • (2005) Circ Res , vol.96 , pp. 501-508
    • Illi, B.1    Scopece, A.2    Nanni, S.3    Farsetti, A.4    Morgante, L.5    Biglioli, P.6
  • 53
    • 23844549198 scopus 로고    scopus 로고
    • Intracellular bacteria differentially regulated endothelial cytokine release by MAPK-dependent histone modification
    • PMID:16116170
    • Schmeck B, Beermann W, van Laak V, Zahlten J, Opitz B, Witzenrath M, et al. Intracellular bacteria differentially regulated endothelial cytokine release by MAPK-dependent histone modification. J Immunol 2005; 175:2843-50; PMID:16116170.
    • (2005) J Immunol , vol.175 , pp. 2843-2850
    • Schmeck, B.1    Beermann, W.2    Van Laak, V.3    Zahlten, J.4    Opitz, B.5    Witzenrath, M.6
  • 54
    • 33746611519 scopus 로고    scopus 로고
    • Activated signal transduction kinases frequently occupy target genes
    • PMID:16873666
    • Pokholok DK, Zeitlinger J, Hannett NM, Reynolds DB, Young RA. Activated signal transduction kinases frequently occupy target genes. Science 2006; 313:533-6; PMID:16873666; http://dx.doi.org/10.1126/science.1127677.
    • (2006) Science , vol.313 , pp. 533-536
    • Pokholok, D.K.1    Zeitlinger, J.2    Hannett, N.M.3    Reynolds, D.B.4    Young, R.A.5
  • 55
    • 33750448996 scopus 로고    scopus 로고
    • Induction of progesterone target genes requires activation of Erk and Msk kinases and phosphorylation of histone H3
    • PMID:17081988
    • Vicent GP, Ballaré C, Nacht AS, Clausell J, Subtil- Rodríguez A, Quiles I, et al. Induction of progesterone target genes requires activation of Erk and Msk kinases and phosphorylation of histone H3. Mol Cell 2006; 24:367-81; PMID:17081988; http://dx.doi.org/10.1016/j.molcel. 2006.10.011.
    • (2006) Mol Cell , vol.24 , pp. 367-381
    • Vicent, G.P.1    Ballaré, C.2    Nacht, A.S.3    Clausell, J.4    Subtil- Rodríguez, A.5    Quiles, I.6
  • 56
    • 33746348338 scopus 로고    scopus 로고
    • Dynamic changes in histone H3 phosphoacetylation during early embryonic stem cell differentiation are directly mediated by mitogen- and stress-activated protein kinase 1 via activation of MAPK pathways
    • PMID:16728397
    • Lee ER, McCool KW, Murdoch FE, Fritsch MK. Dynamic changes in histone H3 phosphoacetylation during early embryonic stem cell differentiation are directly mediated by mitogen- and stress-activated protein kinase 1 via activation of MAPK pathways. J Biol Chem 2006; 281:21162-72; PMID:16728397; http://dx.doi.org/10.1074/jbc.M602734200.
    • (2006) J Biol Chem , vol.281 , pp. 21162-21172
    • Lee, E.R.1    McCool, K.W.2    Murdoch, F.E.3    Fritsch, M.K.4
  • 57
    • 0036668638 scopus 로고    scopus 로고
    • p21-activated kinase 1 interacts with and phosphorylates histone H3 in breast cancer cells
    • PMID:12151336
    • Li F, Adam L, Vadlamudi RK, Zhou H, Sen S, Chernoff J, et al. p21-activated kinase 1 interacts with and phosphorylates histone H3 in breast cancer cells. EMBO Rep 2002; 3:767-73; PMID:12151336; http://dx.doi.org/10.1093/ embo-reports/kvf157.
    • (2002) EMBO Rep , vol.3 , pp. 767-773
    • Li, F.1    Adam, L.2    Vadlamudi, R.K.3    Zhou, H.4    Sen, S.5    Chernoff, J.6
  • 58
    • 23244452354 scopus 로고    scopus 로고
    • Stem cell depletion through epidermal deletion of Rac1
    • PMID:16081735
    • Benitah SA, Frye M, Glogauer M, Watt FM. Stem cell depletion through epidermal deletion of Rac1. Science 2005; 309:933-5; PMID:16081735; http:// dx.doi.org/10.1126/science.1113579.
    • (2005) Science , vol.309 , pp. 933-935
    • Benitah, S.A.1    Frye, M.2    Glogauer, M.3    Watt, F.M.4
  • 59
    • 59649128301 scopus 로고    scopus 로고
    • A positive role for Myc in TGFbeta-induced Snail transcription and epithelial-to-mesenchymal transition
    • PMID:18978814
    • Smith AP, Verrecchia A, Fagà G, Doni M, Perna D, Martinato F, et al. A positive role for Myc in TGFbeta-induced Snail transcription and epithelial-to-mesenchymal transition. Oncogene 2009; 28:422-30; PMID:18978814; http://dx.doi.org/10.1038/onc.2008.395.
    • (2009) Oncogene , vol.28 , pp. 422-430
    • Smith, A.P.1    Verrecchia, A.2    Fagà, G.3    Doni, M.4    Perna, D.5    Martinato, F.6
  • 60
    • 84860389417 scopus 로고    scopus 로고
    • Genome-wide mapping of Myc binding and gene regulation in serum-stimulated fibroblasts
    • PMID:21860422
    • Perna D, Fagà G, Verrecchia A, Gorski MM, Barozzi I, Narang V, et al. Genome-wide mapping of Myc binding and gene regulation in serum-stimulated fibroblasts. Oncogene 2011; PMID:21860422; http://dx.doi.org/10.1038/onc.2011. 359.
    • (2011) Oncogene
    • Perna, D.1    Fagà, G.2    Verrecchia, A.3    Gorski, M.M.4    Barozzi, I.5    Narang, V.6
  • 61
    • 29944444852 scopus 로고    scopus 로고
    • Myc regulates keratinocyte adhesion and differentiation via complex formation with Miz1
    • PMID:16391002
    • Gebhardt A, Frye M, Herold S, Benitah SA, Braun K, Samans B, et al. Myc regulates keratinocyte adhesion and differentiation via complex formation with Miz1. J Cell Biol 2006; 172:139-49; PMID:16391002; http://dx.doi.org/10.1083/ jcb.200506057.
    • (2006) J Cell Biol , vol.172 , pp. 139-149
    • Gebhardt, A.1    Frye, M.2    Herold, S.3    Benitah, S.A.4    Braun, K.5    Samans, B.6
  • 62
    • 33646552414 scopus 로고    scopus 로고
    • The RNA methyltransferase Misu (NSun2) mediates Myc-induced proliferation and is upregulated in tumors
    • PMID:16713953
    • Frye M, Watt FM. The RNA methyltransferase Misu (NSun2) mediates Myc-induced proliferation and is upregulated in tumors. Curr Biol 2006; 16:971-81; PMID:16713953; http://dx.doi.org/10.1016/j.cub.2006.04.027.
    • (2006) Curr Biol , vol.16 , pp. 971-981
    • Frye, M.1    Watt, F.M.2
  • 63
    • 84856161647 scopus 로고    scopus 로고
    • The opposing transcriptional functions of Sin3a and c-Myc are required to maintain tissue homeostasis
    • PMID:22101514
    • Nascimento EM, Cox CL, MacArthur S, Hussain S, Trotter M, Blanco S, et al. The opposing transcriptional functions of Sin3a and c-Myc are required to maintain tissue homeostasis. Nat Cell Biol 2011; 13:1395-405; PMID:22101514; http://dx.doi.org/10.1038/ncb2385.
    • (2011) Nat Cell Biol , vol.13 , pp. 1395-1405
    • Nascimento, E.M.1    Cox, C.L.2    MacArthur, S.3    Hussain, S.4    Trotter, M.5    Blanco, S.6
  • 64
    • 65349166258 scopus 로고    scopus 로고
    • Lrig1 expression defines a distinct multipotent stem cell population in mammalian epidermis
    • PMID:19427292
    • Jensen KB, Collins CA, Nascimento E, Tan DW, Frye M, Itami S, et al. Lrig1 expression defines a distinct multipotent stem cell population in mammalian epidermis. Cell Stem Cell 2009; 4:427-39; PMID:19427292; http://dx.doi.org/10.1016/j.stem.2009.04.014.
    • (2009) Cell Stem Cell , vol.4 , pp. 427-439
    • Jensen, K.B.1    Collins, C.A.2    Nascimento, E.3    Tan, D.W.4    Frye, M.5    Itami, S.6
  • 65
    • 14744305803 scopus 로고    scopus 로고
    • More than just proliferation: Myc function in stem cells
    • PMID:15752976
    • Murphy MJ, Wilson A, Trumpp A. More than just proliferation: Myc function in stem cells. Trends Cell Biol 2005; 15:128-37; PMID:15752976; http:// dx.doi.org/10.1016/j.tcb.2005.01.008.
    • (2005) Trends Cell Biol , vol.15 , pp. 128-137
    • Murphy, M.J.1    Wilson, A.2    Trumpp, A.3
  • 66
    • 8644219660 scopus 로고    scopus 로고
    • c-Myc controls the balance between hematopoietic stem cell self-renewal and differentiation
    • PMID:15545632
    • Wilson A, Murphy MJ, Oskarsson T, Kaloulis K, Bettess MD, Oser GM, et al. c-Myc controls the balance between hematopoietic stem cell self-renewal and differentiation. Genes Dev 2004; 18:2747-63; PMID:15545632; http://dx.doi.org/ 10.1101/gad.313104.
    • (2004) Genes Dev , vol.18 , pp. 2747-2763
    • Wilson, A.1    Murphy, M.J.2    Oskarsson, T.3    Kaloulis, K.4    Bettess, M.D.5    Oser, G.M.6
  • 67
    • 45549093626 scopus 로고    scopus 로고
    • Rho GTPases and regulation of hematopoietic stem cell localization
    • PMID:18374178
    • Williams DA, Zheng Y, Cancelas JA. Rho GTPases and regulation of hematopoietic stem cell localization. Methods Enzymol 2008; 439:365-93; PMID:18374178; http://dx.doi.org/10.1016/S0076-6879(07)00427-2.
    • (2008) Methods Enzymol , vol.439 , pp. 365-393
    • Williams, D.A.1    Zheng, Y.2    Cancelas, J.A.3
  • 68
    • 0033566350 scopus 로고    scopus 로고
    • +Sca-1(+)) while enhancing the terminal maturation of committed granulocyte/monocyte progenitors
    • PMID:10397716
    • +Sca-1(+)) while enhancing the terminal maturation of committed granulocyte/monocyte progenitors. Blood 1999;94:483-95; PMID:10397716.
    • (1999) Blood , vol.94 , pp. 483-495
    • Purton, L.E.1    Bernstein, I.D.2    Collins, S.J.3
  • 69
    • 0034650998 scopus 로고    scopus 로고
    • All-trans retinoic acid enhances the long-term repopulating activity of cultured hematopoietic stem cells
    • PMID:10627451
    • Purton LE, Bernstein ID, Collins SJ. All-trans retinoic acid enhances the long-term repopulating activity of cultured hematopoietic stem cells. Blood 2000;95:470-7; PMID:10627451.
    • (2000) Blood , vol.95 , pp. 470-477
    • Purton, L.E.1    Bernstein, I.D.2    Collins, S.J.3
  • 70
    • 77955330151 scopus 로고    scopus 로고
    • Myc-nick: A cytoplasmic cleavage product of Myc that promotes alpha-tubulin acetylation and cell differentiation
    • PMID:20691906
    • Conacci-Sorrell M, Ngouenet C, Eisenman RN. Myc-nick: a cytoplasmic cleavage product of Myc that promotes alpha-tubulin acetylation and cell differentiation. Cell 2010; 142:480-93; PMID:20691906; http://dx.doi.org/10. 1016/j.cell.2010.06.037.
    • (2010) Cell , vol.142 , pp. 480-493
    • Conacci-Sorrell, M.1    Ngouenet, C.2    Eisenman, R.N.3
  • 71
    • 70350225306 scopus 로고    scopus 로고
    • Activation of RXR and RAR signaling promotes myogenic differentiation of myoblastic C2C12 cells
    • PMID:19560855
    • Zhu GH, Huang J, Bi Y, Su Y, Tang Y, He BC, et al. Activation of RXR and RAR signaling promotes myogenic differentiation of myoblastic C2C12 cells. Differentiation 2009; 78:195-204; PMID:19560855; http://dx.doi.org/10.1016/j. diff.2009.06.001.
    • (2009) Differentiation , vol.78 , pp. 195-204
    • Zhu, G.H.1    Huang, J.2    Bi, Y.3    Su, Y.4    Tang, Y.5    He, B.C.6
  • 72
    • 65549168747 scopus 로고    scopus 로고
    • Differentiation therapy of leukemia: 3 Decades of development
    • PMID:19221035
    • Nowak D, Stewart D, Koeffler HP. Differentiation therapy of leukemia: 3 decades of development. Blood 2009; 113:3655-65; PMID:19221035; http:// dx.doi.org/10.1182/blood-2009-01-198911.
    • (2009) Blood , vol.113 , pp. 3655-3665
    • Nowak, D.1    Stewart, D.2    Koeffler, H.P.3
  • 73
    • 0023752982 scopus 로고
    • Use of all-trans retinoic acid in the treatment of acute promyelocytic leukemia
    • PMID:3165295
    • Huang ME, Ye YC, Chen SR, Chai JR, Lu JX, Zhoa L, et al. Use of all-trans retinoic acid in the treatment of acute promyelocytic leukemia. Blood 1988;72:567-72; PMID:3165295.
    • (1988) Blood , vol.72 , pp. 567-572
    • Huang, M.E.1    Ye, Y.C.2    Chen, S.R.3    Chai, J.R.4    Lu, J.X.5    Zhoa, L.6
  • 74
    • 0038527642 scopus 로고    scopus 로고
    • Methyltransferase recruitment and DNA hypermethylation of target promoters by an oncogenic transcription factor
    • PMID:11834837
    • Di Croce L, Raker VA, Corsaro M, Fazi F, Fanelli M, Faretta M, et al. Methyltransferase recruitment and DNA hypermethylation of target promoters by an oncogenic transcription factor. Science 2002;295:1079-82; PMID:11834837; http://dx.doi.org/10.1126/science.1065173.
    • (2002) Science , vol.295 , pp. 1079-1082
    • Di Croce, L.1    Raker, V.A.2    Corsaro, M.3    Fazi, F.4    Fanelli, M.5    Faretta, M.6
  • 75
    • 17444390135 scopus 로고    scopus 로고
    • Chromatin modifying activity of leukaemia associated fusion proteins
    • PMID:15809276
    • Di Croce L. Chromatin modifying activity of leukaemia associated fusion proteins. Hum Mol Genet 2005; 14:77-84; PMID:15809276; http://dx.doi.org/10. 1093/hmg/ddi109.
    • (2005) Hum Mol Genet , vol.14 , pp. 77-84
    • Di Croce, L.1
  • 76
    • 79954464651 scopus 로고    scopus 로고
    • Dynamics of epigenetic modifications in leukemia
    • PMID:21258047
    • Uribesalgo I, Di Croce L. Dynamics of epigenetic modifications in leukemia. Brief Funct Genomics 2011; 10:18-29; PMID:21258047; http://dx.doi.org/10.1093/bfgp/elr002.
    • (2011) Brief Funct Genomics , vol.10 , pp. 18-29
    • Uribesalgo, I.1    Di Croce, L.2
  • 77
    • 80055000824 scopus 로고    scopus 로고
    • RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia
    • PMID:21814200
    • Zuber J, Shi J, Wang E, Rappaport AR, Herrmann H, Sison EA, et al. RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia. Nature 2011; 478:524-8; PMID:21814200; http:// dx.doi.org/10.1038/nature10334.
    • (2011) Nature , vol.478 , pp. 524-528
    • Zuber, J.1    Shi, J.2    Wang, E.3    Rappaport, A.R.4    Herrmann, H.5    Sison, E.A.6
  • 78
    • 80054984945 scopus 로고    scopus 로고
    • Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia
    • PMID:21964340
    • Dawson MA, Prinjha RK, Dittmann A, Giotopoulos G, Bantscheff M, Chan WI, et al. Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia. Nature 2011; 478:529-33; PMID:21964340; http://dx.doi.org/10.1038/nature10509.
    • (2011) Nature , vol.478 , pp. 529-533
    • Dawson, M.A.1    Prinjha, R.K.2    Dittmann, A.3    Giotopoulos, G.4    Bantscheff, M.5    Chan, W.I.6
  • 79
    • 80052955256 scopus 로고    scopus 로고
    • BET bromodomain inhibition as a therapeutic strategy to target c-Myc
    • PMID:21889194
    • Delmore JE, Issa GC, Lemieux ME, Rahl PB, Shi J, Jacobs HM, et al. BET bromodomain inhibition as a therapeutic strategy to target c-Myc. Cell 2011; 146:904-17; PMID:21889194; http://dx.doi.org/10.1016/j.cell.2011.08.017.
    • (2011) Cell , vol.146 , pp. 904-917
    • Delmore, J.E.1    Issa, G.C.2    Lemieux, M.E.3    Rahl, P.B.4    Shi, J.5    Jacobs, H.M.6
  • 80
  • 82
    • 16944363865 scopus 로고    scopus 로고
    • Characteristic pattern of chromosomal gains and losses in marginal zone B cell lymphoma detected by comparative genomic hybridization
    • PMID:9180302
    • Dierlamm J, Rosenberg C, Stul M, Pittaluga S, Wlodarska I, Michaux L, et al. Characteristic pattern of chromosomal gains and losses in marginal zone B cell lymphoma detected by comparative genomic hybridization. Leukemia 1997; 11:747-58; PMID:9180302; http://dx.doi.org/10.1038/sj.leu.2400635.
    • (1997) Leukemia , vol.11 , pp. 747-758
    • Dierlamm, J.1    Rosenberg, C.2    Stul, M.3    Pittaluga, S.4    Wlodarska, I.5    Michaux, L.6
  • 83
    • 0026660815 scopus 로고
    • Expression of the ETS2 and transferrin receptor genes in Philadelphia-positive chronic myeloid leukemia patients with a reciprocal t(3;21)
    • PMID:1384656
    • Lafage-Pochitaloff M, Courcoul M, Simonetti J, Sainty D, Dastugue N, Tabilio A, et al. Expression of the ETS2 and transferrin receptor genes in Philadelphia-positive chronic myeloid leukemia patients with a reciprocal t(3;21). Genes Chromosomes Cancer 1992; 5:1-13; PMID:1384656; http://dx.doi.org/10.1002/gcc.2870050102.
    • (1992) Genes Chromosomes Cancer , vol.5 , pp. 1-13
    • Lafage-Pochitaloff, M.1    Courcoul, M.2    Simonetti, J.3    Sainty, D.4    Dastugue, N.5    Tabilio, A.6
  • 84
    • 0029150159 scopus 로고
    • Primary cutaneous neuroendocrine tumors. Diagnostic use of cytogenetic and MIC2 analysis
    • PMID:7627931
    • Perlman EJ, Lumadue JA, Hawkins AL, Cohen K, Colombani P, Griffin CA. Primary cutaneous neuroendocrine tumors. Diagnostic use of cytogenetic and MIC2 analysis. Cancer Genet Cytogenet 1995; 82:30-4; PMID:7627931; http://dx.doi.org/10.1016/0165-4608(94)00271-C.
    • (1995) Cancer Genet Cytogenet , vol.82 , pp. 30-34
    • Perlman, E.J.1    Lumadue, J.A.2    Hawkins, A.L.3    Cohen, K.4    Colombani, P.5    Griffin, C.A.6
  • 85
    • 0032511987 scopus 로고    scopus 로고
    • Design and properties of a Myc derivative that efficiently homodimerizes
    • PMID:9824157
    • Soucek L, Helmer-Citterich M, Sacco A, Jucker R, Cesareni G, Nasi S. Design and properties of a Myc derivative that efficiently homodimerizes. Oncogene 1998; 17:2463-72; PMID:9824157; http://dx.doi.org/10.1038/sj.onc. 1202199.
    • (1998) Oncogene , vol.17 , pp. 2463-2472
    • Soucek, L.1    Helmer-Citterich, M.2    Sacco, A.3    Jucker, R.4    Cesareni, G.5    Nasi, S.6
  • 86
    • 53349103292 scopus 로고    scopus 로고
    • Modelling Myc inhibition as a cancer therapy
    • PMID:18716624
    • Soucek L, Whitfield J, Martins CP, Finch AJ, Murphy DJ, Sodir NM, et al. Modelling Myc inhibition as a cancer therapy. Nature 2008; 455:679-83; PMID:18716624; http://dx.doi.org/10.1038/nature07260.
    • (2008) Nature , vol.455 , pp. 679-683
    • Soucek, L.1    Whitfield, J.2    Martins, C.P.3    Finch, A.J.4    Murphy, D.J.5    Sodir, N.M.6
  • 87
    • 0027533679 scopus 로고
    • Oncogenic activity of the c-Myc protein requires dimerization with Max
    • PMID:8425220
    • Amati B, Brooks MW, Levy N, Littlewood TD, Evan GI, Land H. Oncogenic activity of the c-Myc protein requires dimerization with Max. Cell 1993; 72:233-45; PMID:8425220; http://dx.doi.org/10.1016/0092-8674(93)90663-B.
    • (1993) Cell , vol.72 , pp. 233-245
    • Amati, B.1    Brooks, M.W.2    Levy, N.3    Littlewood, T.D.4    Evan, G.I.5    Land, H.6
  • 88
    • 0027364326 scopus 로고
    • The c-Myc protein induces cell cycle progression and apoptosis through dimerization with Max
    • PMID:8262051
    • Amati B, Littlewood TD, Evan GI, Land H. The c-Myc protein induces cell cycle progression and apoptosis through dimerization with Max. EMBO J 1993; 12:5083-7; PMID:8262051.
    • (1993) EMBO J , vol.12 , pp. 5083-5087
    • Amati, B.1    Littlewood, T.D.2    Evan, G.I.3    Land, H.4
  • 89
    • 17944376561 scopus 로고    scopus 로고
    • AML1-ETO expression is directly involved in the development of acute myeloid leukemia in the presence of additional mutations
    • PMID:11526243
    • Yuan Y, Zhou L, Miyamoto T, Iwasaki H, Harakawa N, Hetherington CJ, et al. AML1-ETO expression is directly involved in the development of acute myeloid leukemia in the presence of additional mutations. Proc Natl Acad Sci USA 2001; 98:10398-403; PMID:11526243; http://dx.doi.org/10.1073/pnas.171321298.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 10398-10403
    • Yuan, Y.1    Zhou, L.2    Miyamoto, T.3    Iwasaki, H.4    Harakawa, N.5    Hetherington, C.J.6
  • 90
    • 34249869559 scopus 로고    scopus 로고
    • Role of the polycomb repressive complex 2 in acute promyelocytic leukemia
    • PMID:17560333
    • Villa R, Pasini D, Gutierrez A, Morey L, Occhionorelli M, Viré E, et al. Role of the polycomb repressive complex 2 in acute promyelocytic leukemia. Cancer Cell 2007; 11:513-25; PMID:17560333; http://dx.doi.org/10.1016/ j.ccr.2007.04.009.
    • (2007) Cancer Cell , vol.11 , pp. 513-525
    • Villa, R.1    Pasini, D.2    Gutierrez, A.3    Morey, L.4    Occhionorelli, M.5    Viré, E.6
  • 91
    • 0028091194 scopus 로고
    • A cell initiating human acute myeloid leukaemia after transplantation into SCID mice
    • PMID:7509044
    • Lapidot T, Sirard C, Vormoor J, Murdoch B, Hoang T, Caceres-Cortes J, et al. A cell initiating human acute myeloid leukaemia after transplantation into SCID mice. Nature 1994; 367:645-8; PMID:7509044; http://dx.doi.org/10.1038/ 367645a0.
    • (1994) Nature , vol.367 , pp. 645-648
    • Lapidot, T.1    Sirard, C.2    Vormoor, J.3    Murdoch, B.4    Hoang, T.5    Caceres-Cortes, J.6
  • 92
    • 0030789242 scopus 로고    scopus 로고
    • Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell
    • PMID:9212098
    • Bonnet D, Dick JE. Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell. Nat Med 1997; 3:730-7; PMID:9212098; http://dx.doi.org/10.1038/nm0797-730.
    • (1997) Nat Med , vol.3 , pp. 730-737
    • Bonnet, D.1    Dick, J.E.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.