-
1
-
-
33748192942
-
The Myc oncoprotein as a therapeutic target for human cancer
-
Vita, M. & Henriksson, M. The Myc oncoprotein as a therapeutic target for human cancer. Semin. Cancer Biol. 16, 318 (2006).
-
(2006)
Semin. Cancer Biol
, vol.16
, pp. 318
-
-
Vita, M.1
Henriksson, M.2
-
2
-
-
33748171960
-
The c-Myc target gene network
-
Dang, C.V. et al. The c-Myc target gene network. Semin. Cancer Biol. 16, 253 (2006).
-
(2006)
Semin. Cancer Biol
, vol.16
, pp. 253
-
-
Dang, C.V.1
-
3
-
-
0037334340
-
Transcriptional repression by Myc
-
Wanzel, M., Herold, S. & Eilers, M. Transcriptional repression by Myc. Trends Cell Biol. 13, 146-150 (2003).
-
(2003)
Trends Cell Biol
, vol.13
, pp. 146-150
-
-
Wanzel, M.1
Herold, S.2
Eilers, M.3
-
4
-
-
0026737875
-
Myc and Max proteins possess distinct transcriptional activities
-
Kretzner, L., Blackwood, E.M. & Eisenman, R.N. Myc and Max proteins possess distinct transcriptional activities. Nature 359, 426-429 (1992).
-
(1992)
Nature
, vol.359
, pp. 426-429
-
-
Kretzner, L.1
Blackwood, E.M.2
Eisenman, R.N.3
-
5
-
-
0026665523
-
Transcriptional activation by the human c-Myc oncoprotein in yeast requires interaction with Max
-
Amati, B. et al. Transcriptional activation by the human c-Myc oncoprotein in yeast requires interaction with Max. Nature 359, 423-426 (1992).
-
(1992)
Nature
, vol.359
, pp. 423-426
-
-
Amati, B.1
-
6
-
-
0031036152
-
The Myc negative autoregulation mechanism requires Myc-Max association and involves the c-Myc P2 minimal promoter
-
Facchini, L.M., Chen, S.J., Marhin, W.W., Lear, J.N. & Penn, L.Z. The Myc negative autoregulation mechanism requires Myc-Max association and involves the c-Myc P2 minimal promoter. Mol. Cell. Biol. 17, 100-114 (1997).
-
(1997)
Mol. Cell. Biol
, vol.17
, pp. 100-114
-
-
Facchini, L.M.1
Chen, S.J.2
Marhin, W.W.3
Lear, J.N.4
Penn, L.Z.5
-
7
-
-
0037718341
-
Analysis of Myc bound loci identified by CpG island arrays shows that Max is essential for Myc-dependent repression
-
Mao, D.Y. et al. Analysis of Myc bound loci identified by CpG island arrays shows that Max is essential for Myc-dependent repression. Curr. Biol. 13, 882-886 (2003).
-
(2003)
Curr. Biol
, vol.13
, pp. 882-886
-
-
Mao, D.Y.1
-
8
-
-
0027533679
-
Oncogenic activity of the c-Myc protein requires dimerization with Max
-
Amati, B. et al. Oncogenic activity of the c-Myc protein requires dimerization with Max. Cell 72, 233-245 (1993).
-
(1993)
Cell
, vol.72
, pp. 233-245
-
-
Amati, B.1
-
9
-
-
0027364326
-
The c-Myc protein induces cell cycle progression and apoptosis through dimerization with Max
-
Amati, B., Littlewood, T.D., Evan, G.I. & Land, H. The c-Myc protein induces cell cycle progression and apoptosis through dimerization with Max. EMBO J. 12, 5083-5087 (1993).
-
(1993)
EMBO J
, vol.12
, pp. 5083-5087
-
-
Amati, B.1
Littlewood, T.D.2
Evan, G.I.3
Land, H.4
-
10
-
-
23144464363
-
Transcriptional regulation and transformation by Myc proteins
-
Adhikary, S. & Eilers, M. Transcriptional regulation and transformation by Myc proteins. Nat. Rev. Mol. Cell Biol. 6, 635-645 (2005).
-
(2005)
Nat. Rev. Mol. Cell Biol
, vol.6
, pp. 635-645
-
-
Adhikary, S.1
Eilers, M.2
-
11
-
-
33748136848
-
The MAX-interacting transcription factor network
-
Hurlin, P.J. & Huang, J. The MAX-interacting transcription factor network. Semin. Cancer Biol. 16, 265 (2006).
-
(2006)
Semin. Cancer Biol
, vol.16
, pp. 265
-
-
Hurlin, P.J.1
Huang, J.2
-
12
-
-
0141514041
-
Deletion of Mnt leads to disrupted cell cycle control and tumorigenesis
-
Hurlin, P.J. et al. Deletion of Mnt leads to disrupted cell cycle control and tumorigenesis. EMBO J. 22, 4584-4596 (2003).
-
(2003)
EMBO J
, vol.22
, pp. 4584-4596
-
-
Hurlin, P.J.1
-
13
-
-
0842282553
-
Mnt loss triggers Myc transcription targets, proliferation, apoptosis, and transformation
-
Nilsson, J.A. et al. Mnt loss triggers Myc transcription targets, proliferation, apoptosis, and transformation. Mol. Cell. Biol. 24, 1560-1569 (2004).
-
(2004)
Mol. Cell. Biol
, vol.24
, pp. 1560-1569
-
-
Nilsson, J.A.1
-
14
-
-
0033970535
-
Essential role for Max in early embryonic growth and development
-
Shen-Li, H. et al. Essential role for Max in early embryonic growth and development. Genes Dev. 14, 17-22 (2000).
-
(2000)
Genes Dev
, vol.14
, pp. 17-22
-
-
Shen-Li, H.1
-
15
-
-
0029803667
-
Myc and Max homologs in Drosophila
-
Gallant, P., Shiio, Y., Cheng, P.F., Parkhurst, S.M. & Eisenman, R.N. Myc and Max homologs in Drosophila. Science 274, 1523-1527 (1996).
-
(1996)
Science
, vol.274
, pp. 1523-1527
-
-
Gallant, P.1
Shiio, Y.2
Cheng, P.F.3
Parkhurst, S.M.4
Eisenman, R.N.5
-
16
-
-
0031028183
-
Drosophila Myc is oncogenic in mammalian cells and plays a role in the diminutive phenotype
-
Schreiber-Agus, N. et al. Drosophila Myc is oncogenic in mammalian cells and plays a role in the diminutive phenotype. Proc. Natl. Acad. Sci. USA 94, 1235-1240 (1997).
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 1235-1240
-
-
Schreiber-Agus, N.1
-
17
-
-
0033578793
-
Drosophila myc regulates cellular growth during development
-
Johnston, L.A., Prober, D.A., Edgar, B.A., Eisenman, R.N. & Gallant, P. Drosophila myc regulates cellular growth during development. Cell 98, 779-790 (1999).
-
(1999)
Cell
, vol.98
, pp. 779-790
-
-
Johnston, L.A.1
Prober, D.A.2
Edgar, B.A.3
Eisenman, R.N.4
Gallant, P.5
-
18
-
-
3042796953
-
dMyc is required for larval growth and endoreplication in Drosophila
-
Pierce, S.B. et al. dMyc is required for larval growth and endoreplication in Drosophila. Development 131, 2317-2327 (2004).
-
(2004)
Development
, vol.131
, pp. 2317-2327
-
-
Pierce, S.B.1
-
19
-
-
39549107930
-
Induction of apoptosis by Drosophila Myc
-
Montero, L., Müller, N. & Gallant, P. Induction of apoptosis by Drosophila Myc. Genesis 46, 104-111 (2008).
-
(2008)
Genesis
, vol.46
, pp. 104-111
-
-
Montero, L.1
Müller, N.2
Gallant, P.3
-
20
-
-
1842816486
-
Drosophila myc regulates organ size by inducing cell competition
-
De La Cova, C., Abril, M., Bellosta, P., Gallant, P. & Johnston, L.A. Drosophila myc regulates organ size by inducing cell competition. Cell 117, 107-116 (2004).
-
(2004)
Cell
, vol.117
, pp. 107-116
-
-
De La Cova, C.1
Abril, M.2
Bellosta, P.3
Gallant, P.4
Johnston, L.A.5
-
21
-
-
1842665674
-
dMyc transforms cells into super-competitors
-
Moreno, E. & Basler, K. dMyc transforms cells into super-competitors. Cell 117, 117-129 (2004).
-
(2004)
Cell
, vol.117
, pp. 117-129
-
-
Moreno, E.1
Basler, K.2
-
22
-
-
23044515147
-
Myc, cell competition, and compensatory proliferation
-
Gallant, P. Myc, cell competition, and compensatory proliferation. Cancer Res. 65, 6485-6487 (2005).
-
(2005)
Cancer Res
, vol.65
, pp. 6485-6487
-
-
Gallant, P.1
-
23
-
-
0035856918
-
c-Myc regulates mammalian body size by controlling cell number but not cell size
-
Trumpp, A. et al. c-Myc regulates mammalian body size by controlling cell number but not cell size. Nature 414, 768-773 (2001).
-
(2001)
Nature
, vol.414
, pp. 768-773
-
-
Trumpp, A.1
-
24
-
-
27644514167
-
Human c-Myc isoforms differentially regulate cell growth and apoptosis in Drosophila melanogaster
-
Benassayag, C. et al. Human c-Myc isoforms differentially regulate cell growth and apoptosis in Drosophila melanogaster. Mol. Cell. Biol. 25, 9897-9909 (2005).
-
(2005)
Mol. Cell. Biol
, vol.25
, pp. 9897-9909
-
-
Benassayag, C.1
-
25
-
-
0038523952
-
Genomic binding by the Drosophila Myc, Max, Mad/Mnt transcription factor network
-
Orian, A. et al. Genomic binding by the Drosophila Myc, Max, Mad/Mnt transcription factor network. Genes Dev. 17, 1101-1114 (2003).
-
(2003)
Genes Dev
, vol.17
, pp. 1101-1114
-
-
Orian, A.1
-
26
-
-
17644420711
-
Whole-genome analysis reveals a strong positional bias of conserved dMyc-dependent E-boxes
-
Hulf, T. et al. Whole-genome analysis reveals a strong positional bias of conserved dMyc-dependent E-boxes. Mol. Cell. Biol. 25, 3401-3410 (2005).
-
(2005)
Mol. Cell. Biol
, vol.25
, pp. 3401-3410
-
-
Hulf, T.1
-
27
-
-
14744284578
-
c-Myc binds to human ribosomal DNA and stimulates transcription of rRNA genes by RNA polymerase I
-
Grandori, C. et al. c-Myc binds to human ribosomal DNA and stimulates transcription of rRNA genes by RNA polymerase I. Nat. Cell Biol. 7, 311-318 (2005).
-
(2005)
Nat. Cell Biol
, vol.7
, pp. 311-318
-
-
Grandori, C.1
-
28
-
-
20044375377
-
c-Myc associates with ribosomal DNA and activates RNA polymerase I transcription
-
Arabi, A. et al. c-Myc associates with ribosomal DNA and activates RNA polymerase I transcription. Nat. Cell Biol. 7, 303-310 (2005).
-
(2005)
Nat. Cell Biol
, vol.7
, pp. 303-310
-
-
Arabi, A.1
-
29
-
-
14744297005
-
Myc-dependent regulation of ribosomal RNA synthesis during Drosophila development
-
Grewal, S.S., Li, L., Orian, A., Eisenman, R.N. & Edgar, B.A. Myc-dependent regulation of ribosomal RNA synthesis during Drosophila development. Nat. Cell Biol. 7, 295-302 (2005).
-
(2005)
Nat. Cell Biol
, vol.7
, pp. 295-302
-
-
Grewal, S.S.1
Li, L.2
Orian, A.3
Eisenman, R.N.4
Edgar, B.A.5
-
30
-
-
23344451298
-
The transcriptional repressor dMnt is a regulator of growth in Drosophila melanogaster
-
Loo, L.W. et al. The transcriptional repressor dMnt is a regulator of growth in Drosophila melanogaster. Mol. Cell. Biol. 25, 7078-7091 (2005).
-
(2005)
Mol. Cell. Biol
, vol.25
, pp. 7078-7091
-
-
Loo, L.W.1
-
31
-
-
33144477557
-
Max / Mad in invertebrates - the evolution of the Max network
-
Gallant, P. Myc / Max / Mad in invertebrates - the evolution of the Max network. Curr. Top. Microbiol. Immunol. 302, 235-253 (2006).
-
(2006)
Curr. Top. Microbiol. Immunol
, vol.302
, pp. 235-253
-
-
Gallant, P.M.1
-
32
-
-
39949083011
-
Drosophila growth and development in the absence of dMyc and dMnt
-
Pierce, S.B. et al. Drosophila growth and development in the absence of dMyc and dMnt. Dev. Biol. 315, 303 (2008).
-
(2008)
Dev. Biol
, vol.315
, pp. 303
-
-
Pierce, S.B.1
-
33
-
-
1342306023
-
Drosophila dMyc is required for ovary cell growth and endoreplication
-
Maines, J.Z., Stevens, L.M., Tong, X. & Stein, D. Drosophila dMyc is required for ovary cell growth and endoreplication. Development 131, 775-786 (2004).
-
(2004)
Development
, vol.131
, pp. 775-786
-
-
Maines, J.Z.1
Stevens, L.M.2
Tong, X.3
Stein, D.4
-
34
-
-
0025763419
-
Max: A helix-loop-helix zipper protein that forms a sequence-specific DNA-binding complex with Myc
-
Blackwood, E.M. & Eisenman, R.N. Max: a helix-loop-helix zipper protein that forms a sequence-specific DNA-binding complex with Myc. Science 251, 1211-1217 (1991).
-
(1991)
Science
, vol.251
, pp. 1211-1217
-
-
Blackwood, E.M.1
Eisenman, R.N.2
-
35
-
-
0028037187
-
c-Myc inhibits myogenic differentiation and myoD expression by a mechanism which can be dissociated from cell transformation
-
La Rocca, S.A., Crouch, D.H. & Gillespie, D.A. c-Myc inhibits myogenic differentiation and myoD expression by a mechanism which can be dissociated from cell transformation. Oncogene 9, 3499-3508 (1994).
-
(1994)
Oncogene
, vol.9
, pp. 3499-3508
-
-
La Rocca, S.A.1
Crouch, D.H.2
Gillespie, D.A.3
-
36
-
-
0037462459
-
X-ray structures of Myc-Max and Mad-Max recognizing DNA. Molecular bases of regulation by proto-oncogenic transcription factors
-
Nair, S.K. & Burley, S.K. X-ray structures of Myc-Max and Mad-Max recognizing DNA. Molecular bases of regulation by proto-oncogenic transcription factors. Cell 112, 193-205 (2003).
-
(2003)
Cell
, vol.112
, pp. 193-205
-
-
Nair, S.K.1
Burley, S.K.2
-
37
-
-
0034053414
-
Analysis of Drosophila photoreceptor axon guidance in eye-specific mosaics
-
Newsome, T.P., Asling, B. & Dickson, B.J. Analysis of Drosophila photoreceptor axon guidance in eye-specific mosaics. Development 127, 851-860 (2000).
-
(2000)
Development
, vol.127
, pp. 851-860
-
-
Newsome, T.P.1
Asling, B.2
Dickson, B.J.3
-
38
-
-
33947152396
-
The Trithorax group protein Lid is a trimethyl histone H3K4 demethylase required for dMyc-induced cell growth
-
Secombe, J., Li, L., Carlos, L. & Eisenman, R.N. The Trithorax group protein Lid is a trimethyl histone H3K4 demethylase required for dMyc-induced cell growth. Genes Dev. 21, 537-551 (2007).
-
(2007)
Genes Dev
, vol.21
, pp. 537-551
-
-
Secombe, J.1
Li, L.2
Carlos, L.3
Eisenman, R.N.4
-
39
-
-
29144521539
-
Polycomb mediates Myc autorepression and its transcriptional control of many loci in Drosophila
-
Goodliffe, J.M., Wieschaus, E. & Cole, M.D. Polycomb mediates Myc autorepression and its transcriptional control of many loci in Drosophila. Genes Dev. 19, 2941-2946 (2005).
-
(2005)
Genes Dev
, vol.19
, pp. 2941-2946
-
-
Goodliffe, J.M.1
Wieschaus, E.2
Cole, M.D.3
-
40
-
-
0347721764
-
Direct activation of RNA polymerase III transcription by c-Myc
-
Gomez-Roman, N., Grandori, C., Eisenman, R.N. & White, R.J. Direct activation of RNA polymerase III transcription by c-Myc. Nature 421, 290-294 (2003).
-
(2003)
Nature
, vol.421
, pp. 290-294
-
-
Gomez-Roman, N.1
Grandori, C.2
Eisenman, R.N.3
White, R.J.4
-
41
-
-
33846195889
-
Novel TRF1/BRF target genes revealed by genome-wide analysis of Drosophila Pol III transcription
-
Isogai, Y., Takada, S., Tjian, R. & Keles, S. Novel TRF1/BRF target genes revealed by genome-wide analysis of Drosophila Pol III transcription. EMBO J. 26, 79-89 (2007).
-
(2007)
EMBO J
, vol.26
, pp. 79-89
-
-
Isogai, Y.1
Takada, S.2
Tjian, R.3
Keles, S.4
-
42
-
-
23844454900
-
Myc interacts genetically with Tip48/Reptin and Tip49/Pontin to control growth and proliferation during Drosophila development
-
Bellosta, P. et al. Myc interacts genetically with Tip48/Reptin and Tip49/Pontin to control growth and proliferation during Drosophila development. Proc. Natl. Acad. Sci. USA 102, 11799-11804 (2005).
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 11799-11804
-
-
Bellosta, P.1
-
43
-
-
0035927595
-
Myc drives apoptosis in PC12 cells in the absence of Max
-
Wert, M., Kennedy, S., Palfrey, H.C. & Hay, N. Myc drives apoptosis in PC12 cells in the absence of Max. Oncogene 20, 3746-3750 (2001).
-
(2001)
Oncogene
, vol.20
, pp. 3746-3750
-
-
Wert, M.1
Kennedy, S.2
Palfrey, H.C.3
Hay, N.4
-
44
-
-
33947285072
-
The Myc transactivation domain promotes global phosphorylation of the RNA polymerase II carboxy-terminal domain independently of direct DNA binding
-
Cowling, V.H. & Cole, M.D. The Myc transactivation domain promotes global phosphorylation of the RNA polymerase II carboxy-terminal domain independently of direct DNA binding. Mol. Cell. Biol. 27, 2059-2073 (2007).
-
(2007)
Mol. Cell. Biol
, vol.27
, pp. 2059-2073
-
-
Cowling, V.H.1
Cole, M.D.2
-
45
-
-
33144477930
-
Mechanisms of transcriptional repression by Myc
-
Kleine-Kohlbrecher, D., Adhikary, S. & Eilers, M. Mechanisms of transcriptional repression by Myc. Curr. Top. Microbiol. Immunol. 302, 51-62 (2006).
-
(2006)
Curr. Top. Microbiol. Immunol
, vol.302
, pp. 51-62
-
-
Kleine-Kohlbrecher, D.1
Adhikary, S.2
Eilers, M.3
-
46
-
-
33847660443
-
An optimized transgenesis system for Drosophila using germ-line-specific phiC31 integrases
-
Bischof, J., Maeda, R.K., Hediger, M., Karch, F. & Basler, K. An optimized transgenesis system for Drosophila using germ-line-specific phiC31 integrases. Proc. Natl. Acad. Sci. USA 104, 3312-3317 (2007).
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 3312-3317
-
-
Bischof, J.1
Maeda, R.K.2
Hediger, M.3
Karch, F.4
Basler, K.5
-
47
-
-
0038304516
-
Rheb is an essential regulator of S6K in controlling cell growth in Drosophila
-
Stocker, H. et al. Rheb is an essential regulator of S6K in controlling cell growth in Drosophila. Nat. Cell Biol. 5, 559-565 (2003).
-
(2003)
Nat. Cell Biol
, vol.5
, pp. 559-565
-
-
Stocker, H.1
-
48
-
-
0034716931
-
TRF1:BRF complex directs Drosophila RNA polymerase III transcription
-
Takada, S., Lis, J.T., Zhou, S. & Tjian, R.A. TRF1:BRF complex directs Drosophila RNA polymerase III transcription. Cell 101, 459 (2000).
-
(2000)
Cell
, vol.101
, pp. 459
-
-
Takada, S.1
Lis, J.T.2
Zhou, S.3
Tjian, R.A.4
-
49
-
-
0035253744
-
Growth regulation by oncogenes - new insights from model organisms
-
Prober, D.A. & Edgar, B.A. Growth regulation by oncogenes - new insights from model organisms. Curr. Opin. Genet. Dev. 11, 19-26 (2001).
-
(2001)
Curr. Opin. Genet. Dev
, vol.11
, pp. 19-26
-
-
Prober, D.A.1
Edgar, B.A.2
-
50
-
-
0034681265
-
Ras1 promotes cellular growth in the Drosophila wing
-
Prober, D.A. & Edgar, B.A. Ras1 promotes cellular growth in the Drosophila wing. Cell 100, 435-446 (2000).
-
(2000)
Cell
, vol.100
, pp. 435-446
-
-
Prober, D.A.1
Edgar, B.A.2
|