Catalytic asymmetric mono-fluorination of α-keto esters: Synthesis of optically active β-fluoro-α-hydroxy and β-fluoro-α-amino acid derivatives

Angewandte Chemie - International Edition

Volumn 51, Issue 19, 2012, Pages 4581-4585

  Suzuki, Shoko ^a   Kitamura, Yuki ^a   Lectard, Sylvain ^a   Hamashima, Yoshitaka ^a,b   Sodeoka, Mikiko ^a  

^a RIKEN   (Japan)

^b UNIVERSITY OF SHIZUOKA   (Japan)

Author keywords

keto esters; asymmetric catalysis; fluorination; fluorohydrins; palladium

Indexed keywords

AMINO ACID DERIVATIVES; AMINO ESTERS; ASYMMETRIC CATALYSIS; ENANTIOSELECTIVE; FLUOROHYDRINS; HYDROXO COMPLEXES; HYDROXY ESTERS; KETO ESTER; MEDICINAL CHEMISTRY; ONE POT; OPTICALLY ACTIVE;

AMINO ACIDS; ESTERS; FLUORINATION; FLUORINE; HALOGENATION; PALLADIUM; PALLADIUM COMPOUNDS;

ESTERIFICATION;

AMINO ACID; COORDINATION COMPOUND; ESTER; PALLADIUM;

ARTICLE; CATALYSIS; CHEMISTRY; CONFORMATION; HALOGENATION; STEREOISOMERISM; SYNTHESIS; X RAY CRYSTALLOGRAPHY;

AMINO ACIDS; CATALYSIS; COORDINATION COMPLEXES; CRYSTALLOGRAPHY, X-RAY; ESTERS; HALOGENATION; MOLECULAR CONFORMATION; PALLADIUM; STEREOISOMERISM;

EID: 84860714847     PISSN: 14337851     EISSN: 15213773     Source Type: Journal    
DOI: 10.1002/anie.201201303     Document Type: Article

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