Synthesis and biological evaluation of anti-1-amino-2-[18F]fluoro-cyclobutyl-1-carboxylic acid (anti-2-[18F]FACBC) in rat 9L gliosarcoma

Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 7, 2010, Pages 2140-2143

  Yu, Weiping ^a   Williams, Larry ^a   Camp, Vernon M ^a   Olson, Jeffrey J ^a   Goodman, Mark M ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Amino acids; Brain tumors; Fluorine 18; Non natural; PET

Indexed keywords

1 AMINO 2 FLUORO CYCLOBUTYL 1 CARBOXYLIC ACID FLUORINE 18; AMINO ACID TRANSPORTER; CARBOXYLIC ACID DERIVATIVE; FLUORINE 18; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; BRAIN; CELL ASSAY; CELL TRANSPORT; CONTROLLED STUDY; DRUG DISTRIBUTION; DRUG SYNTHESIS; FLUORINATION; GLIOSARCOMA; INJECTION; ISOTOPE LABELING; NEUROIMAGING; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; RADIOASSAY; RAT; TUMOR CELL;

ANIMALS; BRAIN; CARBOXYLIC ACIDS; CELL LINE, TUMOR; CELL MEMBRANE PERMEABILITY; CYCLOBUTANES; FLUORINE RADIOISOTOPES; GLIOSARCOMA; MALE; POSITRON-EMISSION TOMOGRAPHY; RATS; RATS, INBRED F344;

RATTUS;

EID: 77949489675     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2010.02.048     Document Type: Article

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