TGF-β1 upregulates CX3CR1 expression and inhibits fractalkine-stimulated signaling in rat microglia

Journal of Neuroimmunology

Volumn 133, Issue 1-2, 2002, Pages 46-55

  Chen, Shuzhen ^a   Luo, Defang ^a   Streit, Wolfgang J ^a   Harrison, Jeffrey K ^a  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

Chemokine; CX3CL1; MAPK; Smad

Indexed keywords

CANCER GROWTH FACTOR; CHEMOKINE RECEPTOR; FRACTALKINE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; SMAD PROTEIN; CHEMOKINE (C X3 C MOTIF) LIGAND 1; CHEMOKINE (C-X3-C MOTIF) LIGAND 1; CHEMOKINE RECEPTOR CXCR1; CX3C CHEMOKINE; MEMBRANE PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; TGFB1 PROTEIN, RAT; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL CELL; ARTICLE; BINDING SITE; CELL ADHESION; CELL CULTURE; CONTROLLED STUDY; DRUG EFFECT; DRUG HALF LIFE; ENZYME ACTIVATION; MICROGLIA; NEWBORN; NONHUMAN; PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; STIMULATION; UPREGULATION; ANIMAL; DOSE RESPONSE; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; IMMUNOLOGY; METABOLISM; NERVE DEGENERATION; PATHOPHYSIOLOGY; SPRAGUE DAWLEY RAT; TIME;

ANIMALS; ANIMALS, NEWBORN; CELLS, CULTURED; CHEMOKINES, CX3C; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION REGULATION; MEMBRANE PROTEINS; MICROGLIA; MITOGEN-ACTIVATED PROTEIN KINASES; NERVE DEGENERATION; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, INTERLEUKIN-8A; RNA, MESSENGER; SIGNAL TRANSDUCTION; TIME FACTORS; TRANSCRIPTION, GENETIC; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1; UP-REGULATION;

EID: 0036882109     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-5728(02)00354-5     Document Type: Article

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