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Volumn 6, Issue 11, 2011, Pages

Regulatory T Cells and IL-10 Independently Counterregulate Cytotoxic T Lymphocyte Responses Induced by Transcutaneous Immunization

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; EPITOPE; IMIQUIMOD; INTERLEUKIN 10; INTERLEUKIN 10 RECEPTOR; INTERLEUKIN 10 RECEPTOR ANTIBODY; RECEPTOR ANTIBODY; TOLL LIKE RECEPTOR 7; TRANSCRIPTION FACTOR FOXP3; UNCLASSIFIED DRUG; AMINOQUINOLINE DERIVATIVE; CYTOKINE; FORKHEAD TRANSCRIPTION FACTOR; FOXP3 PROTEIN, MOUSE; HEPARIN BINDING EPIDERMAL GROWTH FACTOR; HEPARIN-BINDING EGF-LIKE GROWTH FACTOR; SIGNAL PEPTIDE;

EID: 84860583088     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0027911     Document Type: Article
Times cited : (18)

References (37)
  • 1
    • 2942558653 scopus 로고    scopus 로고
    • Modulation of immune responses with transcutaneously deliverable adjuvants
    • doi:10.1016/j.vaccine.2003.11.063
    • Partidos CD, Beignon A-S, Briand J-P, Muller S, (2004) Modulation of immune responses with transcutaneously deliverable adjuvants. Vaccine 22: 2385-2390 doi:10.1016/j.vaccine.2003.11.063.
    • (2004) Vaccine , vol.22 , pp. 2385-2390
    • Partidos, C.D.1    Beignon, A.-S.2    Briand, J.-P.3    Muller, S.4
  • 2
    • 0036008014 scopus 로고    scopus 로고
    • Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway
    • doi:10.1038/ni758
    • Hemmi H, Kaisho T, Takeuchi O, Sato S, Sanjo H, et al.(2002) Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway. Nat Immunol 3: 196-200 doi:10.1038/ni758.
    • (2002) Nat Immunol , vol.3 , pp. 196-200
    • Hemmi, H.1    Kaisho, T.2    Takeuchi, O.3    Sato, S.4    Sanjo, H.5
  • 3
    • 0026717120 scopus 로고
    • Inhibition of murine tumor growth by an interferon-inducing imidazoquinolinamine
    • Sidky YA, Borden EC, Weeks CE, Reiter MJ, Hatcher JF, et al.(1992) Inhibition of murine tumor growth by an interferon-inducing imidazoquinolinamine. Cancer Res 52: 3528-3533.
    • (1992) Cancer Res , vol.52 , pp. 3528-3533
    • Sidky, Y.A.1    Borden, E.C.2    Weeks, C.E.3    Reiter, M.J.4    Hatcher, J.F.5
  • 4
    • 0029032284 scopus 로고
    • Cellular requirements for cytokine production in response to the immunomodulators imiquimod and S-27609
    • Gibson SJ, Imbertson LM, Wagner TL, Testerman TL, Reiter MJ, et al.(1995) Cellular requirements for cytokine production in response to the immunomodulators imiquimod and S-27609. J Interferon Cytokine Res 15: 537-545.
    • (1995) J Interferon Cytokine Res , vol.15 , pp. 537-545
    • Gibson, S.J.1    Imbertson, L.M.2    Wagner, T.L.3    Testerman, T.L.4    Reiter, M.J.5
  • 7
    • 0027420347 scopus 로고
    • Phase I trial of an oral immunomodulator and interferon inducer in cancer patients
    • Witt PL, Ritch PS, Reding D, McAuliffe TL, Westrick L, et al.(1993) Phase I trial of an oral immunomodulator and interferon inducer in cancer patients. Cancer Res 53: 5176-5180.
    • (1993) Cancer Res , vol.53 , pp. 5176-5180
    • Witt, P.L.1    Ritch, P.S.2    Reding, D.3    McAuliffe, T.L.4    Westrick, L.5
  • 8
    • 4344697150 scopus 로고    scopus 로고
    • Identification and characterization of pDC-like cells in normal mouse skin and melanomas treated with imiquimod
    • Palamara F, Meindl S, Holcmann M, Lührs P, Stingl G, et al.(2004) Identification and characterization of pDC-like cells in normal mouse skin and melanomas treated with imiquimod. J Immunol 173: 3051-3061.
    • (2004) J Immunol , vol.173 , pp. 3051-3061
    • Palamara, F.1    Meindl, S.2    Holcmann, M.3    Lührs, P.4    Stingl, G.5
  • 9
    • 14044265101 scopus 로고    scopus 로고
    • Cutting edge: priming of CTL by transcutaneous peptide immunization with imiquimod
    • Rechtsteiner G, Warger T, Osterloh P, Schild H, Radsak MP, (2005) Cutting edge: priming of CTL by transcutaneous peptide immunization with imiquimod. J Immunol 174: 2476-2480.
    • (2005) J Immunol , vol.174 , pp. 2476-2480
    • Rechtsteiner, G.1    Warger, T.2    Osterloh, P.3    Schild, H.4    Radsak, M.P.5
  • 10
    • 34247139249 scopus 로고    scopus 로고
    • Transcutaneous immunization with imiquimod is amplified by CD40 ligation and results in sustained cytotoxic T-lymphocyte activation and tumor protection
    • Warger T, Rechtsteiner G, Schmid B, Osterloh P, Schild H, et al.(2007) Transcutaneous immunization with imiquimod is amplified by CD40 ligation and results in sustained cytotoxic T-lymphocyte activation and tumor protection. Clin Rev Allergy Immunol 32: 57-66.
    • (2007) Clin Rev Allergy Immunol , vol.32 , pp. 57-66
    • Warger, T.1    Rechtsteiner, G.2    Schmid, B.3    Osterloh, P.4    Schild, H.5
  • 11
    • 24144494203 scopus 로고    scopus 로고
    • Transcutaneous immunization with cytotoxic T-cell peptide epitopes provides effective antitumor immunity in mice
    • Itoh T, Celis E, (2005) Transcutaneous immunization with cytotoxic T-cell peptide epitopes provides effective antitumor immunity in mice. J Immunother 28: 430-437.
    • (2005) J Immunother , vol.28 , pp. 430-437
    • Itoh, T.1    Celis, E.2
  • 12
    • 40749154946 scopus 로고    scopus 로고
    • Tumor immunotherapy by epicutaneous immunization requires langerhans cells
    • Stoitzner P, Green LK, Jung JY, Price KM, Tripp CH, et al.(2008) Tumor immunotherapy by epicutaneous immunization requires langerhans cells. J Immunol 180: 1991-1998.
    • (2008) J Immunol , vol.180 , pp. 1991-1998
    • Stoitzner, P.1    Green, L.K.2    Jung, J.Y.3    Price, K.M.4    Tripp, C.H.5
  • 13
    • 78650277948 scopus 로고    scopus 로고
    • UV exposure boosts transcutaneous immunization and improves tumor immunity: cytotoxic T-cell priming through the skin
    • doi:10.1038/jid.2010.254
    • Stein P, Rechtsteiner G, Warger T, Bopp T, Fuhr T, et al.(2011) UV exposure boosts transcutaneous immunization and improves tumor immunity: cytotoxic T-cell priming through the skin. J Investig Dermatol 131: 211-219 doi:10.1038/jid.2010.254.
    • (2011) J Investig Dermatol , vol.131 , pp. 211-219
    • Stein, P.1    Rechtsteiner, G.2    Warger, T.3    Bopp, T.4    Fuhr, T.5
  • 14
    • 0035903324 scopus 로고    scopus 로고
    • Synergism of cytotoxic T lymphocyte-associated antigen 4 blockade and depletion of CD25(+) regulatory T cells in antitumor therapy reveals alternative pathways for suppression of autoreactive cytotoxic T lymphocyte responses
    • Sutmuller RP, van Duivenvoorde LM, van Elsas A, Schumacher TN, Wildenberg ME, et al.(2001) Synergism of cytotoxic T lymphocyte-associated antigen 4 blockade and depletion of CD25(+) regulatory T cells in antitumor therapy reveals alternative pathways for suppression of autoreactive cytotoxic T lymphocyte responses. J Exp Med 194: 823-832.
    • (2001) J Exp Med , vol.194 , pp. 823-832
    • Sutmuller, R.P.1    van Duivenvoorde, L.M.2    van Elsas, A.3    Schumacher, T.N.4    Wildenberg, M.E.5
  • 15
    • 21144454780 scopus 로고    scopus 로고
    • Recruitment of latent pools of high-avidity CD8(+) T cells to the antitumor immune response
    • doi:10.1084/jem.20042167
    • Ercolini AM, Ladle BH, Manning EA, Pfannenstiel LW, Armstrong TD, et al.(2005) Recruitment of latent pools of high-avidity CD8(+) T cells to the antitumor immune response. J Exp Med 201: 1591-1602 doi:10.1084/jem.20042167.
    • (2005) J Exp Med , vol.201 , pp. 1591-1602
    • Ercolini, A.M.1    Ladle, B.H.2    Manning, E.A.3    Pfannenstiel, L.W.4    Armstrong, T.D.5
  • 16
    • 17144405680 scopus 로고    scopus 로고
    • Potential role of interleukin-10-secreting regulatory T cells in allergy and asthma
    • doi:10.1038/nri1589
    • Hawrylowicz CM, O'garra A, (2005) Potential role of interleukin-10-secreting regulatory T cells in allergy and asthma. Nat Rev Immunol 5: 271-283 doi:10.1038/nri1589.
    • (2005) Nat Rev Immunol , vol.5 , pp. 271-283
    • Hawrylowicz, C.M.1    O'garra, A.2
  • 17
    • 43049156086 scopus 로고    scopus 로고
    • A regulatory B cell subset with a unique CD1dhiCD5+ phenotype controls T cell-dependent inflammatory responses
    • doi:10.1016/j.immuni.2008.03.017
    • Yanaba K, Bouaziz J-D, Haas KM, Poe JC, Fujimoto M, et al.(2008) A regulatory B cell subset with a unique CD1dhiCD5+ phenotype controls T cell-dependent inflammatory responses. Immunity 28: 639-650 doi:10.1016/j.immuni.2008.03.017.
    • (2008) Immunity , vol.28 , pp. 639-650
    • Yanaba, K.1    Bouaziz, J.-D.2    Haas, K.M.3    Poe, J.C.4    Fujimoto, M.5
  • 19
    • 0027280936 scopus 로고
    • Independent control of immunoglobulin switch recombination at individual switch regions evidenced through Cre-loxP-mediated gene targeting
    • Gu H, Zou YR, Rajewsky K, (1993) Independent control of immunoglobulin switch recombination at individual switch regions evidenced through Cre-loxP-mediated gene targeting. Cell 73: 1155-1164.
    • (1993) Cell , vol.73 , pp. 1155-1164
    • Gu, H.1    Zou, Y.R.2    Rajewsky, K.3
  • 20
    • 0032145327 scopus 로고    scopus 로고
    • Origin and characteristics of ultraviolet-B radiation-induced suppressor T lymphocytes
    • Shreedhar VK, Pride MW, Sun Y, Kripke ML, Strickland FM, (1998) Origin and characteristics of ultraviolet-B radiation-induced suppressor T lymphocytes. J Immunol 161: 1327-1335.
    • (1998) J Immunol , vol.161 , pp. 1327-1335
    • Shreedhar, V.K.1    Pride, M.W.2    Sun, Y.3    Kripke, M.L.4    Strickland, F.M.5
  • 21
    • 0034663943 scopus 로고    scopus 로고
    • Evidence for functional relevance of CTLA-4 in ultraviolet-radiation-induced tolerance
    • Schwarz A, Beissert S, Grosse-Heitmeyer K, Gunzer M, Bluestone JA, et al.(2000) Evidence for functional relevance of CTLA-4 in ultraviolet-radiation-induced tolerance. J Immunol 165: 1824-1831.
    • (2000) J Immunol , vol.165 , pp. 1824-1831
    • Schwarz, A.1    Beissert, S.2    Grosse-Heitmeyer, K.3    Gunzer, M.4    Bluestone, J.A.5
  • 22
    • 67650492400 scopus 로고    scopus 로고
    • Peptide immunotherapy in allergic asthma generates IL-10-dependent immunological tolerance associated with linked epitope suppression
    • doi:10.1084/jem.20082901
    • Campbell JD, Buckland KF, McMillan SJ, Kearley J, Oldfield WLG, et al.(2009) Peptide immunotherapy in allergic asthma generates IL-10-dependent immunological tolerance associated with linked epitope suppression. Journal of Experimental Medicine 206: 1535-1547 doi:10.1084/jem.20082901.
    • (2009) Journal of Experimental Medicine , vol.206 , pp. 1535-1547
    • Campbell, J.D.1    Buckland, K.F.2    McMillan, S.J.3    Kearley, J.4    Oldfield, W.L.G.5
  • 23
    • 0035914841 scopus 로고    scopus 로고
    • The role of interleukin (IL)-10 in the persistence of Leishmania major in the skin after healing and the therapeutic potential of anti-IL-10 receptor antibody for sterile cure
    • Belkaid Y, Hoffmann KF, Mendez S, Kamhawi S, Udey MC, et al.(2001) The role of interleukin (IL)-10 in the persistence of Leishmania major in the skin after healing and the therapeutic potential of anti-IL-10 receptor antibody for sterile cure. J Exp Med 194: 1497-1506.
    • (2001) J Exp Med , vol.194 , pp. 1497-1506
    • Belkaid, Y.1    Hoffmann, K.F.2    Mendez, S.3    Kamhawi, S.4    Udey, M.C.5
  • 24
    • 34250376423 scopus 로고    scopus 로고
    • Cyclic adenosine monophosphate is a key component of regulatory T cell-mediated suppression
    • doi:10.1084/jem.20062129
    • Bopp T, Becker C, Klein M, Klein-Hessling S, Palmetshofer A, et al.(2007) Cyclic adenosine monophosphate is a key component of regulatory T cell-mediated suppression. J Exp Med 204: 1303-1310 doi:10.1084/jem.20062129.
    • (2007) J Exp Med , vol.204 , pp. 1303-1310
    • Bopp, T.1    Becker, C.2    Klein, M.3    Klein-Hessling, S.4    Palmetshofer, A.5
  • 25
    • 64249083235 scopus 로고    scopus 로고
    • Inhibition of cAMP degradation improves regulatory T cell-mediated suppression
    • doi:10.4049/jimmunol.0803310
    • Bopp T, Dehzad N, Reuter S, Klein M, Ullrich N, et al.(2009) Inhibition of cAMP degradation improves regulatory T cell-mediated suppression. The Journal of Immunology 182: 4017-4024 doi:10.4049/jimmunol.0803310.
    • (2009) The Journal of Immunology , vol.182 , pp. 4017-4024
    • Bopp, T.1    Dehzad, N.2    Reuter, S.3    Klein, M.4    Ullrich, N.5
  • 26
    • 0036195161 scopus 로고    scopus 로고
    • CD4(+)CD25(+) immunoregulatory T cells: gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor
    • McHugh RS, Whitters MJ, Piccirillo CA, Young DA, Shevach EM, et al.(2002) CD4(+)CD25(+) immunoregulatory T cells: gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor. Immunity 16: 311-323.
    • (2002) Immunity , vol.16 , pp. 311-323
    • McHugh, R.S.1    Whitters, M.J.2    Piccirillo, C.A.3    Young, D.A.4    Shevach, E.M.5
  • 27
    • 53749094183 scopus 로고    scopus 로고
    • CTLA-4 control over Foxp3+ regulatory T cell function
    • doi:10.1126/science.1160062
    • Wing K, Onishi Y, Prieto-Martin P, Yamaguchi T, Miyara M, et al.(2008) CTLA-4 control over Foxp3+ regulatory T cell function. Science 322: 271-275 doi:10.1126/science.1160062.
    • (2008) Science , vol.322 , pp. 271-275
    • Wing, K.1    Onishi, Y.2    Prieto-Martin, P.3    Yamaguchi, T.4    Miyara, M.5
  • 28
    • 0037099613 scopus 로고    scopus 로고
    • CD4(+)CD25(+) regulatory T cells can mediate suppressor function in the absence of transforming growth factor beta1 production and responsiveness
    • Piccirillo CA, Letterio JJ, Thornton AM, McHugh RS, Mamura M, et al.(2002) CD4(+)CD25(+) regulatory T cells can mediate suppressor function in the absence of transforming growth factor beta1 production and responsiveness. J Exp Med 196: 237-246.
    • (2002) J Exp Med , vol.196 , pp. 237-246
    • Piccirillo, C.A.1    Letterio, J.J.2    Thornton, A.M.3    McHugh, R.S.4    Mamura, M.5
  • 29
    • 46749143803 scopus 로고    scopus 로고
    • TGF-beta-dependent suppressive function of Tregs requires wild-type levels of CD18 in a mouse model of psoriasis
    • doi:10.1172/JCI34916
    • Wang H, Peters T, Sindrilaru A, Kess D, Oreshkova T, et al.(2008) TGF-beta-dependent suppressive function of Tregs requires wild-type levels of CD18 in a mouse model of psoriasis. Journal of Clinical Investigation 118: 2629-2639 doi:10.1172/JCI34916.
    • (2008) Journal of Clinical Investigation , vol.118 , pp. 2629-2639
    • Wang, H.1    Peters, T.2    Sindrilaru, A.3    Kess, D.4    Oreshkova, T.5
  • 30
    • 0038682002 scopus 로고    scopus 로고
    • Mechanisms of TGF-beta signaling from cell membrane to the nucleus
    • Shi Y, Massagué J, (2003) Mechanisms of TGF-beta signaling from cell membrane to the nucleus. Cell 113: 685-700.
    • (2003) Cell , vol.113 , pp. 685-700
    • Shi, Y.1    Massagué, J.2
  • 31
    • 78650880595 scopus 로고    scopus 로고
    • TGFβ: a sleeping giant awoken by integrins
    • doi:10.1016/j.tibs.2010.08.002
    • Worthington JJ, Klementowicz JE, Travis MA, (2011) TGFβ: a sleeping giant awoken by integrins. Trends Biochem Sci 36: 47-54 doi:10.1016/j.tibs.2010.08.002.
    • (2011) Trends Biochem Sci , vol.36 , pp. 47-54
    • Worthington, J.J.1    Klementowicz, J.E.2    Travis, M.A.3
  • 32
    • 33751563152 scopus 로고    scopus 로고
    • Macrophages and myeloid dendritic cells, but not plasmacytoid dendritic cells, produce IL-10 in response to MyD88- and TRIF-dependent TLR signals, and TLR-independent signals
    • Boonstra A, Rajsbaum R, Holman M, Marques R, Asselin-Paturel C, et al.(2006) Macrophages and myeloid dendritic cells, but not plasmacytoid dendritic cells, produce IL-10 in response to MyD88- and TRIF-dependent TLR signals, and TLR-independent signals. J Immunol 177: 7551-7558.
    • (2006) J Immunol , vol.177 , pp. 7551-7558
    • Boonstra, A.1    Rajsbaum, R.2    Holman, M.3    Marques, R.4    Asselin-Paturel, C.5
  • 33
    • 0027056242 scopus 로고
    • Systemic suppression of delayed-type hypersensitivity by supernatants from UV-irradiated keratinocytes. An essential role for keratinocyte-derived IL-10
    • Rivas JM, Ullrich SE, (1992) Systemic suppression of delayed-type hypersensitivity by supernatants from UV-irradiated keratinocytes. An essential role for keratinocyte-derived IL-10. J Immunol 149: 3865-3871.
    • (1992) J Immunol , vol.149 , pp. 3865-3871
    • Rivas, J.M.1    Ullrich, S.E.2
  • 34
    • 79251550415 scopus 로고    scopus 로고
    • Mast cell-derived IL-10 suppresses germinal center formation by affecting T follicular helper cell function
    • doi:10.4049/jimmunol.1001657
    • Chacón-Salinas R, Limón-Flores AY, Chávez-Blanco AD, Gonzalez-Estrada A, Ullrich SE, (2011) Mast cell-derived IL-10 suppresses germinal center formation by affecting T follicular helper cell function. J Immunol 186: 25-31 doi:10.4049/jimmunol.1001657.
    • (2011) J Immunol , vol.186 , pp. 25-31
    • Chacón-Salinas, R.1    Limón-Flores, A.Y.2    Chávez-Blanco, A.D.3    Gonzalez-Estrada, A.4    Ullrich, S.E.5
  • 35
    • 33846423147 scopus 로고    scopus 로고
    • Selective depletion of Foxp3+ regulatory T cells induces a scurfy-like disease
    • doi:10.1084/jem.20061852
    • Lahl K, Loddenkemper C, Drouin C, Freyer J, Arnason J, et al.(2007) Selective depletion of Foxp3+ regulatory T cells induces a scurfy-like disease. J Exp Med 204: 57-63 doi:10.1084/jem.20061852.
    • (2007) J Exp Med , vol.204 , pp. 57-63
    • Lahl, K.1    Loddenkemper, C.2    Drouin, C.3    Freyer, J.4    Arnason, J.5
  • 36
    • 0027521572 scopus 로고
    • Interleukin-10-deficient mice develop chronic enterocolitis
    • Kühn R, Löhler J, Rennick D, Rajewsky K, Müller W, (1993) Interleukin-10-deficient mice develop chronic enterocolitis. Cell 75: 263-274.
    • (1993) Cell , vol.75 , pp. 263-274
    • Kühn, R.1    Löhler, J.2    Rennick, D.3    Rajewsky, K.4    Müller, W.5
  • 37
    • 19944434216 scopus 로고    scopus 로고
    • NFATc2 and NFATc3 transcription factors play a crucial role in suppression of CD4+ T lymphocytes by CD4+ CD25+ regulatory T cells
    • doi:10.1084/jem.20041538
    • Bopp T, Palmetshofer A, Serfling E, Heib V, Schmitt S, et al.(2005) NFATc2 and NFATc3 transcription factors play a crucial role in suppression of CD4+ T lymphocytes by CD4+ CD25+ regulatory T cells. J Exp Med 201: 181-187 doi:10.1084/jem.20041538.
    • (2005) J Exp Med , vol.201 , pp. 181-187
    • Bopp, T.1    Palmetshofer, A.2    Serfling, E.3    Heib, V.4    Schmitt, S.5


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