Transcriptome analysis of a long-lived natural Drosophila variant: a prominent role of stress- and reproduction-genes in lifespan extension

BMC Genomics

Volumn 13, Issue 1, 2012, Pages

  Doroszuk, Agnieszka ^a   Jonker, Martijs J ^b,c   Pul, Nicolien ^a   Breit, Timo M ^b,c   Zwaan, Bas J ^a,d  

^a LEIDEN UNIVERSITY   (Netherlands)

^b UNIVERSITY OF AMSTERDAM   (Netherlands)

^c NETHERLANDS BIOINFORMATICS CENTRE   (Netherlands)

^d WAGENINGEN UNIVERSITY   (Netherlands)

Author keywords

Ageing; Diet; Drosophila melanogaster; Gene expression; Microarray; Natural variation

Indexed keywords

CYTOCHROME P450; TRANSCRIPTOME;

AGING; ARTICLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DIETARY INTAKE; DOWN REGULATION; DROSOPHILA MELANOGASTER; FEMALE; GENE ACTIVITY; GENE EXPRESSION; GENE FUNCTION; GENE NUMBER; IMMUNE RESPONSE; LIFE EXTENSION; LIFESPAN; NONHUMAN; OXIDATIVE PHOSPHORYLATION; PROTEIN DEGRADATION; REPRODUCTION; UPREGULATION;

ANIMALS; DIET; DOWN-REGULATION; DROSOPHILA; DROSOPHILA MELANOGASTER; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENES, INSECT; GENETIC ASSOCIATION STUDIES; HEALTH; LONGEVITY; MODELS, GENETIC; MOLECULAR SEQUENCE ANNOTATION; PRINCIPAL COMPONENT ANALYSIS; REPRODUCTION; STARVATION; STRESS, PHYSIOLOGICAL; SURVIVAL ANALYSIS; UP-REGULATION;

EID: 84860533154     PISSN: None     EISSN: 14712164     Source Type: Journal    
DOI: 10.1186/1471-2164-13-167     Document Type: Article

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