Selective extraction of genotoxic impurities and structurally alerting compounds using polymeric ionic liquid sorbent coatings in solid-phase microextraction: Alkyl halides and aromatics

Journal of Chromatography A

Volumn 1240, Issue , 2012, Pages 29-44

  Ho, Tien D ^a   Joshi, Manishkumar D ^a   Silver, Mark A ^a   Anderson, Jared L ^a  

^a UNIVERSITY OF TOLEDO   (United States)

Author keywords

DNA alkylators; DNA intercalators; Genotoxic impurities; Ionic liquids; Polymeric ionic liquids; Solid phase microextraction

Indexed keywords

ALKYL HALIDES; ANALYTES; CHEMICAL MAKEUP; CHLORIDE ANIONS; CONCENTRATION LEVELS; ETHYL ESTERS; FIBER COATINGS; GENOTOXIC IMPURITIES; HEADSPACE EXTRACTION; HIGH SELECTIVITY; HYDROXYL GROUPS; INTERCALATORS; LIMIT OF DETECTION; LINEAR RANGE; POLYDIMETHYLSILOXANE PDMS; SCANNING ELECTRON MICROGRAPHS; SELECTIVE COATINGS; SELECTIVE EXTRACTION; SOLID-PHASE MICROEXTRACTION; TRIFLUOROMETHYL;

CARBOHYDRATES; CARBOXYLIC ACIDS; CHLORINE COMPOUNDS; COMPLEXATION; HYDROGEN BONDS; IONIC LIQUIDS; IONS; POLYMERS; SCANNING ELECTRON MICROSCOPY; SILICONES; SORBENTS; SORPTION;

COATINGS;

1 BROMODODECANE; 1 BROMOOCTANE; 1 CHLOROBENZENE; 1 CHLOROBUTANE; 1 CHLOROHEXANE; 1 IODOOCTANE; 1,2 DICHLOROBENZENE; 1,8 DIBROMOOOCTANE; 2 METHOXY 5 METHYLANILINE; 2,4 DIMETHYLANILINE; 3 METHYLANILINE; BENZOFURAN; DIMETICONE; FURFURAL; GENOTOXIC IMPURITY; IONIC LIQUID; N,N DIDECYL N METHYL DEXTRO GLUCAMINIUM POLY[2 METHYL ACRYLIC ACID 2 [1 [3 [2 [2 (3 TRIFLUORMETHANESULFONYLAMINO PROPOXY)ETHOXY]ETHOXY]PROPYLAMINO]VINYLAMINO]ETHYL ESTER]; NAPHTHALENE; PHARMACEUTICAL VEHICLES AND ADDITIVES; POLY(1 4 VINYLBENZYL 3 HEXADECYLIMIDAZOLIUM)BIS[(TRIFLUOROMETHYL)SULFONYL]IMIDE; POLY(1 VINYL 3 HEXYLIMIDAZOLIUM)CHLORIDE; POLY(1 VINYL 3 PROPYPHENYLIMIDAZOLIUM)CHLORIDE; POLYACRYLIC ACID; SODIUM CHLORIDE; STYRENE OXIDE; TOXIC SUBSTANCE; UNCLASSIFIED DRUG;

ARTICLE; CARBOHYDRATE ANALYSIS; CHEMICAL STRUCTURE; COATED PARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; HYDROGEN BOND; LIMIT OF DETECTION; MOLECULAR INTERACTION; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROCESS DEVELOPMENT; PROCESS OPTIMIZATION; PURIFICATION; SCANNING ELECTRON MICROSCOPY; SENSITIVITY AND SPECIFICITY; SOLID PHASE MICROEXTRACTION; VALIDATION PROCESS;

DRUG CONTAMINATION; HYDROCARBONS, HALOGENATED; IMIDAZOLES; IONIC LIQUIDS; LIMIT OF DETECTION; MUTAGENS; POLYCYCLIC HYDROCARBONS, AROMATIC; POLYMETHACRYLIC ACIDS; REPRODUCIBILITY OF RESULTS; SODIUM CHLORIDE; SOLID PHASE MICROEXTRACTION;

EID: 84860495902     PISSN: 00219673     EISSN: 18733778     Source Type: Journal    
DOI: 10.1016/j.chroma.2012.03.080     Document Type: Article

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