Somatostatin receptor subtype-4 agonist NNC 26-9100 decreases extracellular and intracellular Aβ1-42 trimers

European Journal of Pharmacology

Volumn 683, Issue 1-3, 2012, Pages 116-124

  Sandoval, Karin E ^a   Farr, Susan A ^b,c   Banks, William A ^d,e   Crider, Albert M ^a   Morley, John E ^b,c   Witt, Ken A ^a  

^a SOUTHERN ILLINOIS UNIVERSITY EDWARDSVILLE   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d VA PUGET SOUND HEALTH CARE SYSTEM   (United States)

^e UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

Amyloid beta oligomers; Neprilysin; NNC 26 9100; Somatostatin receptor subtype 4

Indexed keywords

1 [3 [N (5 BROMO 2 PYRIDYL) N (3,4 DICHLOROBENZYL)AMINO]PROPYL] 3 [3 (4 IMIDAZOLYL)PROPYL]THIOUREA; AMYLOID BETA PROTEIN[1-42]; AMYLOID PRECURSOR PROTEIN; MEMBRANE METALLOENDOPEPTIDASE; SOMATOSTATIN RECEPTOR 4;

ACUTE DRUG ADMINISTRATION; AMNESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN TISSUE; CELL FRACTIONATION; CONTROLLED STUDY; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG EFFECT; DRUG SCREENING; ENZYME ACTIVITY; EXTRACELLULAR MATRIX; HIPPOCAMPUS; INTRACELLULAR MEMBRANE; LEARNING DISORDER; MALE; MAZE TEST; MOUSE; NONHUMAN; OLIGOMERIZATION; OPTIMAL DRUG DOSE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; SINGLE DRUG DOSE; TREATMENT DURATION; VISUAL MEMORY;

AMINOPYRIDINES; AMYLOID BETA-PEPTIDES; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; CEREBRAL CORTEX; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; EXTRACELLULAR FLUID; HIPPOCAMPUS; INJECTIONS, INTRAVENTRICULAR; MALE; MAZE LEARNING; MEMORY; MICE; MICE, INBRED STRAINS; MOLECULAR WEIGHT; NEPRILYSIN; NERVE TISSUE PROTEINS; NEURONS; NOOTROPIC AGENTS; PEPTIDE FRAGMENTS; RECEPTORS, SOMATOSTATIN; SOLUBILITY; THIOUREA;

EID: 84860446155     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2012.03.020     Document Type: Article

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