Evaluation of the anti-angiogenic potential of hydroxytyrosol and tyrosol, two bio-active phenolic compounds of extra virgin olive oil, in endothelial cell cultures

Food Chemistry

Volumn 134, Issue 1, 2012, Pages 134-140

  Fortes, Carolina ^a   García Vilas, Javier A ^a   Quesada, Ana R ^a,b   Medina, Miguel Ángel ^a,b  

^a UNIVERSITY OF MÁLAGA   (Spain)

^b CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED DE ENFERMEDADES RARAS CIBERER   (Spain)

Author keywords

Angiogenesis; Hydroxytyrosol; Mediterranean diet; Olive oil; Tyrosol

Indexed keywords

ANGIOGENESIS; HYDROXYTYROSOL; MEDITERRANEAN DIET; OLIVE OIL; TYROSOL;

CELL CULTURE; CELL PROLIFERATION; PHENOLS; VEGETABLE OILS;

ENDOTHELIAL CELLS;

ANGIOGENESIS INHIBITOR; GELATINASE A; HYDROXYTYROSOL; OLIVE OIL; TYROSOL;

ANTIANGIOGENIC ACTIVITY; APOPTOSIS; ARTICLE; CELL CYCLE; CELL MIGRATION; CELL PROLIFERATION; CELL STRUCTURE; CONTROLLED STUDY; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; IN VITRO STUDY;

EID: 84860382175     PISSN: 03088146     EISSN: 18737072     Source Type: Journal    
DOI: 10.1016/j.foodchem.2012.02.079     Document Type: Article

References (39)

1. R. Auerbach, R. Lewis, B. Shinners, L. Kubai, and N. Akhtar Angiogenesis assays: A critical overview Clinical Chemistry 49 1 2003 32 40
2. G.K. Beauchamp, R.S. Keast, D. Morel, J. Lin, J. Pika, Q. Han, C.H. Lee, A.B. Smith, and P.A. Breslin Phytochemistry: Ibuprofen-like activity in extra-virgin olive oil Nature 437 7055 2005 45 46
3. F. Bellisle, A.R. Diplock, G. Hornstra, B. Koletzko, M. Roberfroid, S. Salminen, and W.H.M. Saris Functional food in Europe British Journal of Nutrition 80 1998 S1 S93
4. C. Cárdenas, A.R. Quesada, and M.A. Medina Evaluation of the anti-angiogenic effect of aloe-emodin Cellular and Molecular Life Sciences 63 24 2006 3083 3089
5. C. Cárdenas, A.R. Quesada, and M.A. Medina Anti-angiogenic and anti-inflammatory properties of kahweol, a coffee diterpene PLoS ONE 6 8 2011 e23407
6. G. Corona, M. Deiana, A. Incani, D. Vauzour, M.A. Dessi, and J.P. Spencer Hydroxytyrosol inhibits the proliferation of human colon adenocarcinoma cells through inhibition of ERK1/2 and cyclin D1 Molecular Nutrition & Food Research 53 7 2009 897 903
7. Y. Da-Peng, D. Kong, and H. Zhang Multiple pharmacological effects of olive oil phenols Food Chemistry 104 2007 1269 1271
8. A.Y. Elnagar, P.W. Sylvester, and K.A. El Sayed (-)-Oleocanthal as a c-Met inhibitor for the control of metastatic breast and prostate cancers Planta Medica 77 10 2011 1013 1019
9. M.I. Fernández-Mar, R. Mateos, M.C. García-Parrilla, B. Puertas, and E. Cantos-Villar Bioactive compounds in wine: Resveratrol, hydroxytyrosol and melatonin: a review Food Chemistry 130 2012 797 813
10. J. Folkman Angiogenesis: An organizing principle for drug discovery? Nature Reviews Drug Discovery 6 4 2007 273 286
11. C. Giovannini, E. Straface, D. Modesti, E. Coni, A. Cantafora, M. De Vincenzi, W. Malorni, and R. Masella Tyrosol, the major olive oil biophenol, protects against oxidized-LDL-induced injury in Caco-2 cells Journal of Nutrition 129 7 1999 1269 1277
12. D. Gong, C. Geng, L. Jiang, J. Cao, H. Yoshimura, and L. Zhong Effects of hydroxytyrosol-20 on carrageenan-induced acute inflammation and hyperalgesia in rats Phytotherapy Research 23 5 2009 646 650
13. S. Granados-Principal, J.L. Quiles, C.L. Ramirez-Tortosa, P. Sanchez-Rovira, and M.C. Ramirez-Tortosa Hydroxytyrosol: from laboratory investigations to future clinical trials Nutrition Reviews 68 4 2010 191 206
14. S.C. Gupta, J.H. Kim, S. Prasad, and B.B. Aggarwal Regulation of survival, proliferation, invasion, angiogenesis, and metastasis of tumor cells through modulation of inflammatory pathways by nutraceuticals Cancer and Metastasis Reviews 29 3 2010 405 434
15. K. Hamden, N. Allouche, M. Damak, and A. Elfeki Hypoglycemic and antioxidant effects of phenolic extracts and purified hydroxytyrosol from olive mill waste in vitro and in rats Chemico-Biological Interactions 180 3 2009 421 432
16. B. Juhasz, B. Varga, R. Gesztelyi, A. Kemeny-Beke, J. Zsuga, and A. Tosaki Resveratrol: A multifunctional cytoprotective molecule Current Pharmaceutical Biotechnology 11 8 2010 810 818
17. B. Martínez-Poveda, A.R. Quesada, and M.A. Medina Hyperforin, a bio-active compound of St. John's Wort, is a new inhibitor of angiogenesis targeting several key steps of the process International Journal of Cancer 117 5 2005 775 780
18. B. Martínez-Poveda, A.R. Quesada, and M.A. Medina Hypericin in the dark inhibits key steps of angiogenesis in vitro European Journal of Pharmacology 516 2 2005 97 103
19. E. Medina, A. de Castro, C. Romero, and M. Brenes Comparison of the concentrations of phenolic compounds in olive oils and other plant oils: Correlation with antimicrobial activity Journal of Agriculture and Food Chemistry 54 14 2006 4954 4961
20. M.A. Medina, R. Muñoz-Chápuli, and A.R. Quesada Challenges of antiangiogenic cancer therapy: Trials and errors, and renewed hope Journal of Cellular and Molecular Medicine 11 3 2007 374 382
21. E. Melgarejo, J.L. Urdiales, F. Sanchez-Jimenez, and M.A. Medina Targeting polyamines and biogenic amines by green tea epigallocatechin-3-gallate Amino Acids 38 2 2010 519 523
22. R.W. Owen, A. Giacosa, W.E. Hull, R. Haubner, G. Wurtele, B. Spiegelhalder, and H. Bartsch Olive-oil consumption and health: The possible role of antioxidants Lancet Oncology 1 2000 107 112
23. R.W. Owen, R. Haubner, G. Wurtele, E. Hull, B. Spiegelhalder, and H. Bartsch Olives and olive oil in cancer prevention European Journal of Cancer Prevention 13 4 2004 319 326
24. M.B. Plotnikov, G.A. Chernysheva, V.I. Smol'yakova, M.Y. Maslov, I.V. Cherkashina, A.P. Krysin, I.V. Sorokina, and T.G. Tolstikova Effect of n-tyrosol on blood viscosity and platelet aggregation Bulletin of Experimental Biology and Medicine 143 1 2007 61 63
25. M. Potente, H. Gerhardt, and P. Carmeliet Basic and therapeutic aspects of angiogenesis Cell 146 6 2011 873 887
26. A.R. Quesada, M.A. Medina, and E. Alba Playing only one instrument may be not enough: Limitations and future of the antiangiogenic treatment of cancer BioEssays 29 11 2007 1159 1168
27. A.R. Quesada, M.A. Medina, R. Muñoz-Chápuli, and A.L. Ponce Do not say ever never more: The ins and outs of antiangiogenic therapies Current Pharmaceutical Design 16 35 2010 3932 3957
28. A.R. Quesada, R. Muñoz-Chápuli, and M.A. Medina Anti-angiogenic drugs: From bench to clinical trials Medicinal Research Reviews 26 4 2006 483 530
29. S.M. Samuel, M. Thirunavukkarasu, S.V. Penumathsa, D. Paul, and N. Maulik Akt/FOXO3a/SIRT1-mediated cardioprotection by n-tyrosol against ischemic stress in rat in vivo model of myocardial infarction: Switching gears toward survival and longevity Journal of Agriculture and Food Chemistry 56 20 2008 9692 9698
30. R. Sirianni, A. Chimento, A. De Luca, I. Casaburi, P. Rizza, A. Onofrio, D. Iacopetta, F. Puoci, S. Ando, M. Maggiolini, and V. Pezzi Oleuropein and hydroxytyrosol inhibit MCF-7 breast cancer cell proliferation interfering with ERK1/2 activation Molecular Nutrition & Food Research 54 6 2010 833 840
31. P.J. Slininger, K.D. Burkhead, and D.A. Schisler Antifungal and sprout regulatory bioactivities of phenylacetic acid, indole-3-acetic acid, and tyrosol isolated from the potato dry rot suppressive bacterium Enterobacter cloacae S11:T:07 Journal of Industrial Microbiology and Biotechnology 31 11 2004 517 524
32. C.A. Staton, M.W. Reed, and N.J. Brown A critical analysis of current in vitro and in vivo angiogenesis assays International Journal of Experimental Pathology 90 3 2009 195 221
33. W.G. Stetler-Stevenson Matrix metalloproteinases in angiogenesis: A moving target for therapeutic intervention Journal of Clinical Investigation 103 9 1999 1237 1241
34. C. St-Laurent-Thibault, M. Arseneault, F. Longpre, and C. Ramassamy Tyrosol and hydroxytyrosol, two main components of olive oil, protect N2a cells against amyloid-beta-induced toxicity. Involvement of the NF-kappaB signaling Current Alzheimer Research 8 5 2011 543 551
35. E. Tripoli, M. Giammanco, G. Tabacchi, D. Di Majo, S. Giammanco, and M. La Guardia The phenolic compounds of olive oil: Structure, biological activity and beneficial effects on human health Nutrition Research Reviews 18 1 2005 98 112
36. J.R. van Beijnum, E. van der Linden, and A.W. Griffioen Angiogenic profiling and comparison of immortalized endothelial cells for functional genomics Experimental Cell Research 314 2 2008 264 272
37. U. Wahrburg, M. Kratz, and P. Cullen Mediterranean diet, olive oil and health European Journal of Lipid Science and Technology 104 2002 698 705
38. H. Zhou, C.S. Beevers, and S. Huang The targets of curcumin Current Drug Targets 12 3 2011 332 347
39. V. Ziogas, G. Tanou, A. Molassiotis, and G. Diamantidis Antioxidant and free radical-scavenging activities of phenolic extracts of olive fruits Food Chemistry 120 2010 1097 1103