-
1
-
-
0037699955
-
Angiogenesis in health and disease
-
Carmeliet P. Angiogenesis in health and disease. Nat Med. 2003 9 : 653 60.
-
(2003)
Nat Med.
, vol.9
, pp. 653-60
-
-
Carmeliet, P.1
-
2
-
-
30744479430
-
Angiogenesis in life, disease and medicine
-
Carmeliet P. Angiogenesis in life, disease and medicine. Nature. 2005 438 : 932 6.
-
(2005)
Nature.
, vol.438
, pp. 932-6
-
-
Carmeliet, P.1
-
4
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan D, Weinberg RA. The hallmarks of cancer. Cell. 2000 100 : 57 70.
-
(2000)
Cell.
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
6
-
-
0034092011
-
Tumor angiogenesis: Past, present and the near future
-
Kerbel RS. Tumor angiogenesis: Past, present and the near future. Carcinogenesis. 2000 21 : 505 15.
-
(2000)
Carcinogenesis.
, vol.21
, pp. 505-15
-
-
Kerbel, R.S.1
-
7
-
-
0035479234
-
Tumor angiogenesis as a therapeutic target
-
Matter A. Tumor angiogenesis as a therapeutic target. Drug Disc Today. 2001 6 : 1005 24.
-
(2001)
Drug Disc Today.
, vol.6
, pp. 1005-24
-
-
Matter, A.1
-
9
-
-
33845299567
-
In vivo models of angiogenesis
-
Norrby N. In vivo models of angiogenesis. J Cell Mol Med. 2006 10 : 588 612.
-
(2006)
J Cell Mol Med.
, vol.10
, pp. 588-612
-
-
Norrby, N.1
-
11
-
-
0037967272
-
Tumorigenesis and the angiogenic switch
-
Bergers G, Benjamin LE. Tumorigenesis and the angiogenic switch. Nat Rev Cancer. 2003 3 : 401 10.
-
(2003)
Nat Rev Cancer.
, vol.3
, pp. 401-10
-
-
Bergers, G.1
Benjamin, L.E.2
-
14
-
-
0037134709
-
Clinical application of antiangiogenic therapy: Microvessel density, what it does and doesn't tell us
-
Hlatky L, Hahnfeldt P, Folkman J. Clinical application of antiangiogenic therapy: Microvessel density, what it does and doesn't tell us. J Natl Cancer Inst. 2002 98 : 883 93.
-
(2002)
J Natl Cancer Inst.
, vol.98
, pp. 883-93
-
-
Hlatky, L.1
Hahnfeldt, P.2
Folkman, J.3
-
15
-
-
0035477472
-
In vivo intracellular signaling as a marker of antiangiogenic activity
-
Solorzano CC, Jung YD, Bucana CD, McConkey DJ, Gallick GE, McMahon G, Ellis LM. In vivo intracellular signaling as a marker of antiangiogenic activity. Cancer Res. 2001 61 : 7048 51.
-
(2001)
Cancer Res.
, vol.61
, pp. 7048-51
-
-
Solorzano, C.C.1
Jung, Y.D.2
Bucana, C.D.3
McConkey, D.J.4
Gallick, G.E.5
McMahon, G.6
Ellis, L.M.7
-
16
-
-
0035360833
-
Kinetics and viability of circulating endothelial cells as surrogate angiogenesis marker in an animal model of human lymphoma
-
Monestiroli S, Mancuso P, Burlini A, Pruneri G, Dell'Agnolo C, Gobbi A, Martinelli G, Bertolini F. Kinetics and viability of circulating endothelial cells as surrogate angiogenesis marker in an animal model of human lymphoma. Cancer Res. 2001 61 : 4341 4.
-
(2001)
Cancer Res.
, vol.61
, pp. 4341-4
-
-
Monestiroli, S.1
Mancuso, P.2
Burlini, A.3
Pruneri, G.4
Dell'Agnolo, C.5
Gobbi, A.6
Martinelli, G.7
Bertolini, F.8
-
18
-
-
0034793679
-
Sequential tumor biopsies in early phase clinical trials of anticancer agents for pharmacodynamic evaluation
-
Dowlati A, Haaga J, Remick SC, Spiro TP, Gerson SL, Liu L, Berger SJ, Berger NA, Willson JK. Sequential tumor biopsies in early phase clinical trials of anticancer agents for pharmacodynamic evaluation. Clin Cancer Res. 2001 7 : 2971 6.
-
(2001)
Clin Cancer Res.
, vol.7
, pp. 2971-6
-
-
Dowlati, A.1
Haaga, J.2
Remick, S.C.3
Spiro, T.P.4
Gerson, S.L.5
Liu, L.6
Berger, S.J.7
Berger, N.A.8
Willson, J.K.9
-
19
-
-
0038376002
-
Molecular regulation of vessel maturation
-
Jain RK. Molecular regulation of vessel maturation. Nat Med. 2003 9 : 685 93.
-
(2003)
Nat Med.
, vol.9
, pp. 685-93
-
-
Jain, R.K.1
-
20
-
-
0038376001
-
Imaging of angiogenesis: From microscope to clinic
-
McDonald DM, Choyke PL. Imaging of angiogenesis: From microscope to clinic. Nat Med. 2003 9 : 713 25.
-
(2003)
Nat Med.
, vol.9
, pp. 713-25
-
-
McDonald, D.M.1
Choyke, P.L.2
-
22
-
-
0036286634
-
-
Kaur M, Reed E, Sartor O, Dahut W, Figg WD. Suramin's development: What did we learn? Invest New Drugs. 2002 20 : 209 19.
-
(2002)
Suramin's Development: What Did We Learn? Invest New Drugs
, vol.20
, pp. 209-19
-
-
Kaur, M.1
Reed, E.2
Sartor, O.3
Dahut, W.4
Figg, W.D.5
-
23
-
-
10744227780
-
A phase II trial of suramine monthly ×3 for hormone-refractory prostate carcinoma
-
Vogelzang NJ, Karrison T, Stadler WM, García J, Cohn H, Troeger T, Giannone L, Arrieta R, Ratain MJ, Vokes EE. A phase II trial of suramine monthly ×3 for hormone-refractory prostate carcinoma. Cancer. 2004 100 : 65 71.
-
(2004)
Cancer.
, vol.100
, pp. 65-71
-
-
Vogelzang, N.J.1
Karrison, T.2
Stadler, W.M.3
García, J.4
Cohn, H.5
Troeger, T.6
Giannone, L.7
Arrieta, R.8
Ratain, M.J.9
Vokes, E.E.10
-
24
-
-
33847048710
-
Alternative vascularization mechanisms in cancer: Pathology and therapeutic implications
-
Dome B, Hendrix MJ, Paku S, Tovari J, Timar J. Alternative vascularization mechanisms in cancer: Pathology and therapeutic implications. Am J Pathol. 2007 170 : 1 15.
-
(2007)
Am J Pathol.
, vol.170
, pp. 1-15
-
-
Dome, B.1
Hendrix, M.J.2
Paku, S.3
Tovari, J.4
Timar, J.5
-
25
-
-
33750286135
-
The multifaceted circulating endothelial cell in cancer: Towards marker and target identification
-
Bertolini F, Shaked Y, Mancuso P, Kerbel RS. The multifaceted circulating endothelial cell in cancer: Towards marker and target identification. Nat Rev Cancer. 2006 6 : 835 45.
-
(2006)
Nat Rev Cancer.
, vol.6
, pp. 835-45
-
-
Bertolini, F.1
Shaked, Y.2
Mancuso, P.3
Kerbel, R.S.4
-
26
-
-
34547358822
-
Tumor stroma fosters neovascularization by recruitment of progenitr cells into the tumor bed
-
Ganss R. Tumor stroma fosters neovascularization by recruitment of progenitr cells into the tumor bed. J Cell Mol Med. 2006 10 : 857 65.
-
(2006)
J Cell Mol Med.
, vol.10
, pp. 857-65
-
-
Ganss, R.1
-
27
-
-
33144468586
-
Monocytes/macrophages cooperate with progenitor cells during neovascularization and tissue repair: Conversion of cell columns into fibrovascular bundles
-
Anghelina M, Krishnan P, Moldovan L, Moldovan NI. Monocytes/macrophages cooperate with progenitor cells during neovascularization and tissue repair: Conversion of cell columns into fibrovascular bundles. Am J Pathol. 2006 168 : 529 41.
-
(2006)
Am J Pathol.
, vol.168
, pp. 529-41
-
-
Anghelina, M.1
Krishnan, P.2
Moldovan, L.3
Moldovan, N.I.4
-
28
-
-
33845312332
-
A subpopulation of peritoneal macrophages form capillarylike lumens and branching patterns in vitro
-
Anghelina M, Moldovan L, Zabuawala T, Ostrowski MC, Moldovan NI. A subpopulation of peritoneal macrophages form capillarylike lumens and branching patterns in vitro. J Cell Mol Med. 2006 10 : 708 15.
-
(2006)
J Cell Mol Med.
, vol.10
, pp. 708-15
-
-
Anghelina, M.1
Moldovan, L.2
Zabuawala, T.3
Ostrowski, M.C.4
Moldovan, N.I.5
-
29
-
-
0030722076
-
Non-small-cell lung carcinoma tumor growth without morphological evidence of neo-angiogenesis
-
Pezzella F, Pastorino U, Tagliabue E, Andreola S, Sozzi G, Gasparini G, Menard S, Gatter KC, Harris AL, Fox S, Buyse M, Pilotti S. Non-small-cell lung carcinoma tumor growth without morphological evidence of neo-angiogenesis. Am J Pathol. 1997 151 : 1417 23.
-
(1997)
Am J Pathol.
, vol.151
, pp. 1417-23
-
-
Pezzella, F.1
Pastorino, U.2
Tagliabue, E.3
Andreola, S.4
Sozzi, G.5
Gasparini, G.6
Menard, S.7
Gatter, K.C.8
Harris, A.L.9
Fox, S.10
Buyse, M.11
Pilotti, S.12
-
30
-
-
0033580889
-
Vessel cooption, regression, and growth in tumors mediated by angiopoietins and VEGF
-
Holash J, Maisonpierre PC, Compton D, Boland P, Alexander CR, Zagzag D, Yancopoulos GD, Wiegand SJ. Vessel cooption, regression, and growth in tumors mediated by angiopoietins and VEGF. Science. 1999 284 : 1994 8.
-
(1999)
Science.
, vol.284
, pp. 1994-8
-
-
Holash, J.1
Maisonpierre, P.C.2
Compton, D.3
Boland, P.4
Alexander, C.R.5
Zagzag, D.6
Yancopoulos, G.D.7
Wiegand, S.J.8
-
33
-
-
30744477450
-
Lymphangiogenesis in development and human disease
-
Alitalo K, Tammela T, Petrova TV. Lymphangiogenesis in development and human disease. Nature. 2005 438 : 946 53.
-
(2005)
Nature.
, vol.438
, pp. 946-53
-
-
Alitalo, K.1
Tammela, T.2
Petrova, T.V.3
-
34
-
-
0031747280
-
The next frontier of molecular medicine: Delivery of therapeutics
-
Jain RK. The next frontier of molecular medicine: Delivery of therapeutics. Nat Med. 1998 4 : 655 7.
-
(1998)
Nat Med.
, vol.4
, pp. 655-7
-
-
Jain, R.K.1
-
36
-
-
0043177668
-
Bevacizumab (a monoclonal antibody to vascular endothelial growth factor) prolongs survival in first-line colorectal cancer (CRC): Results of a phase III trial of bevacizumab in combination with bolus IFL (irinotecan, 5-fluorouracil, leucovorin) as a first-line therapy in subjects with metastatic CRC
-
Hurwitz H, Fehrenbacher L, Cartwright T, Hainsworth J, Heim W, Berlin S, Griffing S, Novotny W, Holmgren E, Kabbinavar F. Bevacizumab (a monoclonal antibody to vascular endothelial growth factor) prolongs survival in first-line colorectal cancer (CRC): Results of a phase III trial of bevacizumab in combination with bolus IFL (irinotecan, 5-fluorouracil, leucovorin) as a first-line therapy in subjects with metastatic CRC. Proc Am Soc Clin Oncol Meeting. 2003 3646.
-
(2003)
Proc Am Soc Clin Oncol Meeting.
, pp. 3646
-
-
Hurwitz, H.1
Fehrenbacher, L.2
Cartwright, T.3
Hainsworth, J.4
Heim, W.5
Berlin, S.6
Griffing, S.7
Novotny, W.8
Holmgren, E.9
Kabbinavar, F.10
-
37
-
-
2542561964
-
Bevacizumab plus Irinotecan, Fluorouracil, and Leucovorin for metastatic colorectal cancer
-
Hurwitz H, Fehrenbacher L, Novotny W, Cartwright T, Hainsworth J, Heim W, Berlin S, Baron A, Griffing S, Holmgren E, Ferrara N, Fyfe G, Rogers B, Ross R, Kabbinavar F. Bevacizumab plus Irinotecan, Fluorouracil, and Leucovorin for metastatic colorectal cancer. N Engl J Med. 2004 350 : 2335 42.
-
(2004)
N Engl J Med.
, vol.350
, pp. 2335-42
-
-
Hurwitz, H.1
Fehrenbacher, L.2
Novotny, W.3
Cartwright, T.4
Hainsworth, J.5
Heim, W.6
Berlin, S.7
Baron, A.8
Griffing, S.9
Holmgren, E.10
Ferrara, N.11
Fyfe, G.12
Rogers, B.13
Ross, R.14
Kabbinavar, F.15
-
38
-
-
2542520723
-
Two steps forward in the treatment of col-orectal cancer
-
Mayer RJ. Two steps forward in the treatment of col-orectal cancer. N Engl J Med. 2004 350 : 2406 8.
-
(2004)
N Engl J Med.
, vol.350
, pp. 2406-8
-
-
Mayer, R.J.1
-
39
-
-
33750366159
-
Bevacizumab for the treatment of metastatic colorectal cancer (mCRC) in second- and third-line settings
-
Giantonio BJ. Bevacizumab for the treatment of metastatic colorectal cancer (mCRC) in second- and third-line settings. Semin Oncol. 2006 33 : S15 8.
-
(2006)
Semin Oncol.
, vol.33
-
-
Giantonio, B.J.1
-
40
-
-
33845490014
-
Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer
-
Sandler A, Gray R, Perry MC, Brahmer J, Schiller JH, Dowlati A, Lilenbaum R, Johnson DH. Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer. N Engl J Med. 2006 355 : 2542 50.
-
(2006)
N Engl J Med.
, vol.355
, pp. 2542-50
-
-
Sandler, A.1
Gray, R.2
Perry, M.C.3
Brahmer, J.4
Schiller, J.H.5
Dowlati, A.6
Lilenbaum, R.7
Johnson, D.H.8
-
41
-
-
33646867029
-
Sorafenib: Recent update on activity as a single agent in combination with interferon-alpha2 in patients with advanced-stage renal cell carcinoma
-
Reddy GK, Bukowski RM. Sorafenib: Recent update on activity as a single agent in combination with interferon-alpha2 in patients with advanced-stage renal cell carcinoma. Clin Genitourin Cancer. 2006 4 : 246 8.
-
(2006)
Clin Genitourin Cancer.
, vol.4
, pp. 246-8
-
-
Reddy, G.K.1
Bukowski, R.M.2
-
42
-
-
33749505836
-
Efficacy and safety of sunitinib in patients with advanced gastrointestinal stromal tumour after failure of imatinib: A randomised controlled trial
-
Demetri GD, van Oosterrom AT, Garrett CR, Blackstein ME, Shah MH, Verweij J, McArthur G, Judson IR, Heirinch MC, Morgan JA, Desai J, Fletcher CD, George S, Bello CL, Huang X, Baum CM, Casali PG. Efficacy and safety of sunitinib in patients with advanced gastrointestinal stromal tumour after failure of imatinib: A randomised controlled trial. Lancet. 2006 368 : 1329 38.
-
(2006)
Lancet.
, vol.368
, pp. 1329-38
-
-
Demetri, G.D.1
Van Oosterrom, A.T.2
Garrett, C.R.3
Blackstein, M.E.4
Shah, M.H.5
Verweij, J.6
McArthur, G.7
Judson, I.R.8
Heirinch, M.C.9
Morgan, J.A.10
Desai, J.11
Fletcher, C.D.12
George, S.13
Bello, C.L.14
Huang, X.15
Baum, C.M.16
Casali, P.G.17
-
43
-
-
33746127995
-
Molecular targeting therapy for renal cell carcinoma
-
Eto M, Naito S. Molecular targeting therapy for renal cell carcinoma. Int J Clin Oncol. 2006 11 : 209 13.
-
(2006)
Int J Clin Oncol.
, vol.11
, pp. 209-13
-
-
Eto, M.1
Naito, S.2
-
44
-
-
1642321097
-
Evaluating antiangiogenesis agents in the clinic: The Eastern Cooperative Oncology Group Portfolio of Clinical Trials
-
Sparano JA, Gray R, Giantonio B, O'Dwyer P, Comis RL. Evaluating antiangiogenesis agents in the clinic: The Eastern Cooperative Oncology Group Portfolio of Clinical Trials. Clin Cancer Res. 2004 10 : 1206 11.
-
(2004)
Clin Cancer Res.
, vol.10
, pp. 1206-11
-
-
Sparano, J.A.1
Gray, R.2
Giantonio, B.3
O'Dwyer, P.4
Comis, R.L.5
-
45
-
-
0034796595
-
Normalizing tumor vasculature with anti-angiogenic therapy: A new paradigm for combination therapy
-
Jain RK. Normalizing tumor vasculature with anti-angiogenic therapy: A new paradigm for combination therapy. Nat Med. 2001 7 : 987 9.
-
(2001)
Nat Med.
, vol.7
, pp. 987-9
-
-
Jain, R.K.1
-
46
-
-
19944432454
-
Genetic heterogeneity of the vasculogenic phenotype parallels angiogenesis: Implications for cellular surrogate marker analysis of antiangiogenesis
-
Shaked Y, Bertolini F, Man S, Rogers MS, Cervi D, Foutz T, Rawn K, Voskas D, Dumont DJ, Ben-David Y, Lawler J, Henkin J, Huber J, Hicklin DJ, D'Amato RJ, Kerbel RS. Genetic heterogeneity of the vasculogenic phenotype parallels angiogenesis: Implications for cellular surrogate marker analysis of antiangiogenesis. Cancer Cell. 2005 7 : 101 11.
-
(2005)
Cancer Cell.
, vol.7
, pp. 101-11
-
-
Shaked, Y.1
Bertolini, F.2
Man, S.3
Rogers, M.S.4
Cervi, D.5
Foutz, T.6
Rawn, K.7
Voskas, D.8
Dumont, D.J.9
Ben-David, Y.10
Lawler, J.11
Henkin, J.12
Huber, J.13
Hicklin, D.J.14
D'Amato, R.J.15
Kerbel, R.S.16
-
47
-
-
0035214416
-
Metronomic scheduling: The future of chemotherapy?
-
Gasparini G. Metronomic scheduling: The future of chemotherapy? Lancet Oncol. 2001 2 : 733 40.
-
(2001)
Lancet Oncol.
, vol.2
, pp. 733-40
-
-
Gasparini, G.1
-
48
-
-
2942615257
-
The anti-angiogenic basis of metronomic chemotherapy
-
Kerbel RS, Kamen BA. The anti-angiogenic basis of metronomic chemotherapy. Nat Rev Cancer. 2004 4 : 423 36.
-
(2004)
Nat Rev Cancer.
, vol.4
, pp. 423-36
-
-
Kerbel, R.S.1
Kamen, B.A.2
-
49
-
-
0038626211
-
Tumor response to radiotherapy regulated by endothe-lial cell apoptosis
-
García-Barros M, Paris F, Cordon-Cardo C, Lyden D, Rafii S, Haimovitz-Friedman A, Fuks Z, Kolesnick R. Tumor response to radiotherapy regulated by endothe-lial cell apoptosis. Science. 2003 300 : 964 7.
-
(2003)
Science.
, vol.300
, pp. 964-7
-
-
García-Barros, M.1
Paris, F.2
Cordon-Cardo, C.3
Lyden, D.4
Rafii, S.5
Haimovitz-Friedman, A.6
Fuks, Z.7
Kolesnick, R.8
-
50
-
-
0025093973
-
Vascular attack as a therapeutic strategy for cancer
-
Denekamp J. Vascular attack as a therapeutic strategy for cancer. Cancer Metastasis Rev. 1990 9 : 267 82.
-
(1990)
Cancer Metastasis Rev.
, vol.9
, pp. 267-82
-
-
Denekamp, J.1
-
51
-
-
0037373826
-
The First International Conference on Vascular Targeting: Meeting overview
-
Thorpe PE, Chaplin DJ, Blakey DC. The First International Conference on Vascular Targeting: Meeting overview. Cancer Res. 2003 63 : 1144 7.
-
(2003)
Cancer Res.
, vol.63
, pp. 1144-7
-
-
Thorpe, P.E.1
Chaplin, D.J.2
Blakey, D.C.3
-
52
-
-
1642472018
-
Antiangiogenic therapy and tumor progression
-
Blagosklonny MV. Antiangiogenic therapy and tumor progression. Cancer Cell. 2004 5 : 13 7.
-
(2004)
Cancer Cell.
, vol.5
, pp. 13-7
-
-
Blagosklonny, M.V.1
-
53
-
-
0042411985
-
Tumor hypoxia, chemotherapeutic resistance and hypoxia-related therapies
-
Shannon AM., Bouchier-Hayes DJ, Condron CH, Toomey D. Tumor hypoxia, chemotherapeutic resistance and hypoxia-related therapies. Cancer Treat Rev. 2003 29 : 297 307.
-
(2003)
Cancer Treat Rev.
, vol.29
, pp. 297-307
-
-
Shannon, A.M.1
Bouchier-Hayes, D.J.2
Condron, C.H.3
Toomey, D.4
-
54
-
-
0042131613
-
Therapeutic potential of selective cyclooxygenase-2 inhibitors in the management of tumor angiogenesis
-
Gately S, Kerbel R. Therapeutic potential of selective cyclooxygenase-2 inhibitors in the management of tumor angiogenesis. Prog Exp Tumor Res. 2003 37 : 179 92.
-
(2003)
Prog Exp Tumor Res.
, vol.37
, pp. 179-92
-
-
Gately, S.1
Kerbel, R.2
-
55
-
-
20144365496
-
Cardiovascular risk associated with celecoxib in a clinical trial for colorectal adenoma prevention
-
Adenoma Prevention with Celecoxib (APC) Study Investigators.
-
Solomon SD, McMurray JJ, Pfeffer MA, Wittes J, Fowler R, Finn P, Anderson WF, Zauber A, Hawk E, Bertagnolli M, Adenoma Prevention with Celecoxib (APC) Study Investigators. Cardiovascular risk associated with celecoxib in a clinical trial for colorectal adenoma prevention. N Engl J Med. 2005 352 : 1071 80.
-
(2005)
N Engl J Med.
, vol.352
, pp. 1071-80
-
-
Solomon, S.D.1
McMurray, J.J.2
Pfeffer, M.A.3
Wittes, J.4
Fowler, R.5
Finn, P.6
Anderson, W.F.7
Zauber, A.8
Hawk, E.9
Bertagnolli, M.10
-
56
-
-
19744380776
-
Cardiovascular events associated with rofecoxib in a colorectal adenoma prevention trial
-
Adenomatous Polyp Prevention on Vioxx (APPROVe) Trial Investigators.
-
Bresalier RS, Sandler RS, Quan H, Bolognese JA, Oxenius B, Horgan K, Lines C, Riddell R, Morton D, Lanas A, Konstam MA, Baron JA, Adenomatous Polyp Prevention on Vioxx (APPROVe) Trial Investigators. Cardiovascular events associated with rofecoxib in a colorectal adenoma prevention trial. N Engl J Med. 2005 352 : 1092 102.
-
(2005)
N Engl J Med.
, vol.352
, pp. 1092-102
-
-
Bresalier, R.S.1
Sandler, R.S.2
Quan, H.3
Bolognese, J.A.4
Oxenius, B.5
Horgan, K.6
Lines, C.7
Riddell, R.8
Morton, D.9
Lanas, A.10
Konstam, M.A.11
Baron, J.A.12
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