메뉴 건너뛰기




Volumn 2, Issue , 2007, Pages 3-30

Significance of protein kinase a in cancer

Author keywords

8 Cl cAMP; antisense PKA RI; cancer; CRE transcription factor decoy; growth inhibition; Protein kinase A; tumor reversion

Indexed keywords


EID: 84860317548     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/978-1-59745-199-4_1     Document Type: Chapter
Times cited : (3)

References (169)
  • 1
    • 0001559662 scopus 로고
    • Fractionation and characterization of a cyclic adenine ribonucleotide formed by tissue particles
    • Sutherland EW, Rall TW. Fractionation and characterization of a cyclic adenine ribonucleotide formed by tissue particles. J Biol Chem 1958;232:1077-1092.
    • (1958) J Biol Chem , vol.232 , pp. 1077-1092
    • Sutherland, E.W.1    Rall, T.W.2
  • 2
    • 0014409394 scopus 로고
    • An adenosine 3', 5'-monophosphate-dependant protein kinase from rabbit skeletal muscle
    • Walsh DA, Perkins JP, Krebs EG. An adenosine 3', 5'-monophosphate- dependant protein kinase from rabbit skeletal muscle. J Biol Chem 1968;243:3763-3765.
    • (1968) J Biol Chem , vol.243 , pp. 3763-3765
    • Walsh, D.A.1    Perkins, J.P.2    Krebs, E.G.3
  • 3
    • 0015042684 scopus 로고
    • Role of the receptor in the mechanism of action of adenosine 3':5'-cyclic monophosphate
    • Gill GN, Garren LD. Role of the receptor in the mechanism of action of adenosine 3':5'-cyclic monophosphate. Proc Natl Acad Sci USA 1971;68:786-790.
    • (1971) Proc Natl Acad Sci USA , vol.68 , pp. 786-790
    • Gill, G.N.1    Garren, L.D.2
  • 4
    • 0014653971 scopus 로고
    • Cyclic nucleotide-dependent protein kinases IV. Widespread occurrence of adenosine 3':5'-monophosphate-dependent protein kinase in various tissues and phyla of the animal kingdom
    • Kuo JF, Greengard P. Cyclic nucleotide-dependent protein kinases IV. Widespread occurrence of adenosine 3':5'-monophosphate-dependent protein kinase in various tissues and phyla of the animal kingdom. Proc Natl Acad Sci USA 1969;64:1349-1355.
    • (1969) Proc Natl Acad Sci USA , vol.64 , pp. 1349-1355
    • Kuo, J.F.1    Greengard, P.2
  • 5
    • 77956929978 scopus 로고
    • Cyclic nucleotide-dependent protein kinases
    • Krebs EG, Boyer PD, eds Orlando and London. Academic Press, New York
    • Beebe SJ, Corbin JD. Cyclic nucleotide-dependent protein kinases. In: Krebs EG, Boyer PD, eds. The Enzymes: Control by Phosphorylation. Orlando and London. Academic Press, New York, 1986:43-111.
    • (1986) The Enzymes: Control by Phosphorylation , pp. 43-111
    • Beebe, S.J.1    Corbin, J.D.2
  • 6
    • 0027265948 scopus 로고
    • The genetic subtypes of cAMP-dependent protein kinase-functionally different or redundant?
    • Døskeland SO, Maronde E, Gjertsen BT. The genetic subtypes of cAMP-dependent protein kinase-functionally different or redundant? Biochim Biophys Acta 1993;1178(3): 249-258.
    • (1993) Biochim Biophys Acta , vol.1178 , Issue.3 , pp. 249-258
    • Døskeland, S.O.1    Maronde, E.2    Gjertsen, B.T.3
  • 7
    • 0015217626 scopus 로고
    • Purification and properties of rabbit skeletal muscle adenosine 3':5'-monophosphate-dependent protein kinases
    • Reimann EM, Walsh DA, Krebs EG. Purification and properties of rabbit skeletal muscle adenosine 3':5'-monophosphate-dependent protein kinases. J Biol Chem 1971;246:1986-1995.
    • (1971) J Biol Chem , vol.246 , pp. 1986-1995
    • Reimann, E.M.1    Walsh, D.A.2    Krebs, E.G.3
  • 8
    • 0016430836 scopus 로고
    • The distribution and dissociation of cyclic adenosine 3', 5'-monophosphate-dependent protein kinases in adipose, cardiac, and other tissues
    • Corbin JD, Keely SL, Park CR. The distribution and dissociation of cyclic adenosine 3', 5'-monophosphate-dependent protein kinases in adipose, cardiac, and other tissues. J Biol Chem 1975;250:218-225.
    • (1975) J Biol Chem , vol.250 , pp. 218-225
    • Corbin, J.D.1    Keely, S.L.2    Park, C.R.3
  • 9
    • 0020770086 scopus 로고
    • Isolation of a cDNA clone for the type i regulatory subunit of bovine cAMP-dependent protein kinase
    • Lee DC, Carmichael DF, Krebs EG, McKnight GS. Isolation of a cDNA clone for the type I regulatory subunit of bovine cAMP-dependent protein kinase. Proc Natl Acad Sci USA 1983;80:3608-3612.
    • (1983) Proc Natl Acad Sci USA , vol.80 , pp. 3608-3612
    • Lee, D.C.1    Carmichael, D.F.2    Krebs, E.G.3    McKnight, G.S.4
  • 10
    • 0023572029 scopus 로고
    • Molecular cloning, cDNA structure and deduced amino acid sequence for a type i regulatory subunit of cAMP-dependent protein kinase from human testis
    • Sandberg M, Tasken K, Oyen O, Hansson V, Jahnsen T. Molecular cloning, cDNA structure and deduced amino acid sequence for a type I regulatory subunit of cAMP-dependent protein kinase from human testis. Biochem Biophys Res Commun 1987;149:939-945.
    • (1987) Biochem Biophys Res Commun , vol.149 , pp. 939-945
    • Sandberg, M.1    Tasken, K.2    Oyen, O.3    Hansson, V.4    Jahnsen, T.5
  • 11
    • 0011564219 scopus 로고
    • Genetic characterization of a brain-specific form of the type i regulatory subunit of cAMP-dependent protein kinase
    • Clegg CH, Cadd GG, McKnight GS. Genetic characterization of a brain-specific form of the type I regulatory subunit of cAMP-dependent protein kinase. Proc Natl Acad Sci USA 1988;85:3703-3707.
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 3703-3707
    • Clegg, C.H.1    Cadd, G.G.2    McKnight, G.S.3
  • 12
    • 0025915104 scopus 로고
    • Molecular cloning, cDNA structure and tissue-specific expression of the human regulatory subunit RI beta of cAMP-dependent protein kinases
    • Solberg R, Tasken K, Keiserud A, Jahnsen T. Molecular cloning, cDNA structure and tissue-specific expression of the human regulatory subunit RI beta of cAMP-dependent protein kinases. Biochem Biophys Res Commun 1991;176:166-172.
    • (1991) Biochem Biophys Res Commun , vol.176 , pp. 166-172
    • Solberg, R.1    Tasken, K.2    Keiserud, A.3    Jahnsen, T.4
  • 13
    • 0023388024 scopus 로고
    • The molecular cloning of a type II regulatory subunit of the cAMP-dependent protein kinase from rat skeletal muscle and mouse brain
    • Scott JD, Glaccum MB, Zoller MJ, Uhler MD, Helfman DM, McKnight GS, et al. The molecular cloning of a type II regulatory subunit of the cAMP-dependent protein kinase from rat skeletal muscle and mouse brain. Proc Natl Acad Sci USA 1987;84:5192-5196.
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 5192-5196
    • Scott, J.D.1    Glaccum, M.B.2    Zoller, M.J.3    Uhler, M.D.4    Helfman, D.M.5    McKnight, G.S.6
  • 14
    • 0024549994 scopus 로고
    • Human testis cDNA for the regulatory subunit RII alpha of cAMP-dependent protein kinase encodes an alternate amino-terminal region
    • Øyen O, Myklebust F, Scott JD, Hansson V, Jahnsen T. Human testis cDNA for the regulatory subunit RII alpha of cAMP-dependent protein kinase encodes an alternate amino-terminal region. FEBS Lett 1989;246:57-64.
    • (1989) FEBS Lett , vol.246 , pp. 57-64
    • Øyen, O.1    Myklebust, F.2    Scott, J.D.3    Hansson, V.4    Jahnsen, T.5
  • 15
    • 0022966782 scopus 로고
    • Molecular cloning, cDNA structure, and regulation of the regulatory subunit of type II cAMP-dependent protein kinase from rat ovarian granulosa cells
    • Jahnsen T, Hedin L, Kidd VJ, Beattie WG, Lohmann SM, Walter U, et al. Molecular cloning, cDNA structure, and regulation of the regulatory subunit of type II cAMP-dependent protein kinase from rat ovarian granulosa cells. J Biol Chem 1986;261:12,352-12,361.
    • (1986) J Biol Chem , vol.261 , pp. 12352-12361
    • Jahnsen, T.1    Hedin, L.2    Kidd, V.J.3    Beattie, W.G.4    Lohmann, S.M.5    Walter, U.6
  • 16
    • 0024232624 scopus 로고
    • Molecular cloning, complementary deoxyribonucleic acid structure and predicted full-length amino acid sequence of the hormone-inducible regulatory subunit of 3', 5'-cyclic adenosine monophosphate-dependent protein kinase from human testis
    • Levy FO, Oyen O, Sandberg M, Tasken K, Eskild W, Hansson V, et al. Molecular cloning, complementary deoxyribonucleic acid structure and predicted full-length amino acid sequence of the hormone-inducible regulatory subunit of 3', 5'-cyclic adenosine monophosphate-dependent protein kinase from human testis. Mol Endocrinol 1988;2: 1364-1373.
    • (1988) Mol Endocrinol , vol.2 , pp. 1364-1373
    • Levy, F.O.1    Oyen, O.2    Sandberg, M.3    Tasken, K.4    Eskild, W.5    Hansson, V.6
  • 18
    • 0023000363 scopus 로고
    • Evidence for a second isoform of the catalytic subunit of cAMP-dependent protein kinase
    • 360-15, 363
    • Uhler MD, Chrivia JC, McKnight GS. Evidence for a second isoform of the catalytic subunit of cAMP-dependent protein kinase. J Biol Chem 1986;261:15, 360-15, 363.
    • (1986) J Biol Chem , vol.261 , Issue.15
    • Uhler, M.D.1    Chrivia, J.C.2    McKnight, G.S.3
  • 19
    • 0022894653 scopus 로고
    • A cloned bovine cDNA encodes an alternate form of the catalytic subunit of cAMP-dependent protein kinase
    • 291
    • Showers MO, Maurer RA. A cloned bovine cDNA encodes an alternate form of the catalytic subunit of cAMP-dependent protein kinase. J Biol Chem 1986;261:16, 288-16, 291.
    • (1986) J Biol Chem , vol.261 , Issue.16 , pp. 288-216
    • Showers, M.O.1    Maurer, R.A.2
  • 20
    • 0025343605 scopus 로고
    • Molecular cloning of a unique tissue-specific protein kinase (C-gamma) from human testis-representing a third isoform for the catalytic subunit of the cAMP-dependent protein kinase
    • Beebe SJ, Oyen O, Sandberg M, Froysa A, Hansson V, Jahnsen T. Molecular cloning of a unique tissue-specific protein kinase (C-gamma) from human testis-representing a third isoform for the catalytic subunit of the cAMP-dependent protein kinase. Mol Endocrinol 1990;4:465-475.
    • (1990) Mol Endocrinol , vol.4 , pp. 465-475
    • Beebe, S.J.1    Oyen, O.2    Sandberg, M.3    Froysa, A.4    Hansson, V.5    Jahnsen, T.6
  • 21
    • 84900977438 scopus 로고
    • CAMP-dependent protein kinase from pig brain: Subunit structure, mechanism of autophosphorylation and dissociation into subunits under the action of cAMP
    • Ulmasov KhA, Nesterova MV, Severin ES. cAMP-dependent protein kinase from pig brain: subunit structure, mechanism of autophosphorylation and dissociation into subunits under the action of cAMP Biochemistry (N.Y.) 1980;45:639-647.
    • (1980) Biochemistry (N.Y.) , vol.45 , pp. 639-647
    • Kha, U.1    Nesterova, M.V.2    Severin, E.S.3
  • 23
    • 0016772776 scopus 로고
    • Comparison of adenosine 3', 5'-monophos-phate-dependent protein kinase from rabbit skeletal and bovine heart muscle
    • Hofman F, Beavo JA, Bechtel PJ, Krebs EG. Comparison of adenosine 3', 5'-monophos-phate-dependent protein kinase from rabbit skeletal and bovine heart muscle. J Biol Chem 1975;250:7795-7801.
    • (1975) J Biol Chem , vol.250 , pp. 7795-7801
    • Hofman, F.1    Beavo, J.A.2    Bechtel, P.J.3    Krebs, E.G.4
  • 24
    • 0017070921 scopus 로고
    • Mechanism of self-phosphorylation of adenosine 3':5'-monophosphate- depedent protein kinase from bovine cardiac muscle
    • Rangel-Aldao R, Rosen OM. Mechanism of self-phosphorylation of adenosine 3':5'-monophosphate-depedent protein kinase from bovine cardiac muscle. J Biol Chem 1976;251:3375-3380.
    • (1976) J Biol Chem , vol.251 , pp. 3375-3380
    • Rangel-Aldao, R.1    Rosen, O.M.2
  • 25
    • 0025365945 scopus 로고
    • Probing the cyclic nucleotide binding sites of cAMP-dependent protein kinases i and II with analogs of adenosine 3', 5'-cyclic phosphorothioates
    • Dostmann WR, Taylor SS, Genieser HG, Jastorff B, Doskeland SO, Ogreid D. Probing the cyclic nucleotide binding sites of cAMP-dependent protein kinases I and II with analogs of adenosine 3', 5'-cyclic phosphorothioates. J Biol Chem 1990;265:10, 484-10, 491.
    • (1990) J Biol Chem , vol.265 , pp. 10484-10491
    • Dostmann, W.R.1    Taylor, S.S.2    Genieser, H.G.3    Jastorff, B.4    Doskeland, S.O.5    Ogreid, D.6
  • 26
    • 0019332260 scopus 로고
    • Apparent constants for the interaction of regulatory and catalytic subunit of cAMP-dependent protein kinase i and II
    • Hofman F. Apparent constants for the interaction of regulatory and catalytic subunit of cAMP-dependent protein kinase I and II. J Biol Chem 1980;255:1559-1564.
    • (1980) J Biol Chem , vol.255 , pp. 1559-1564
    • Hofman, F.1
  • 27
    • 0024398714 scopus 로고
    • Overexpression of the type II regulatory subunit of the cAMP-dependent protein kinase eliminates the type i holoenzyme in mouse cells
    • Otten AD, McKnight GS. Overexpression of the type II regulatory subunit of the cAMP-dependent protein kinase eliminates the type I holoenzyme in mouse cells. J Biol Chem 1989;264:20, 255-20, 260.
    • (1989) J Biol Chem , vol.264 , pp. 20255-20260
    • Otten, A.D.1    McKnight, G.S.2
  • 28
    • 0030614908 scopus 로고    scopus 로고
    • Compensatory regulation of RIalpha protein levels in protein kinase A mutant mice
    • Amieux PS, Cummings DE, Motamed K, Brandon EP, Wailes LA, Le K, et al. Compensatory regulation of RIalpha protein levels in protein kinase A mutant mice. J Biol Chem 1997;272:3993-3998.
    • (1997) J Biol Chem , vol.272 , pp. 3993-3998
    • Amieux, P.S.1    Cummings, D.E.2    Motamed, K.3    Brandon, E.P.4    Wailes, L.A.5    Le, K.6
  • 29
    • 0027454488 scopus 로고
    • Novel isozymes of cAMP-dependent protein kinase exist in human cells due to formation of RI alpha-RI beta heterodimeric complexes
    • Tasken K, Skalhegg BS, Solberg R, Andersson KB, Taylor SS, Lea T, et al. Novel isozymes of cAMP-dependent protein kinase exist in human cells due to formation of RI alpha-RI beta heterodimeric complexes. J Biol Chem 1993;268:21, 276-21, 283.
    • (1993) J Biol Chem , vol.268 , pp. 21276-21283
    • Tasken, K.1    Skalhegg, B.S.2    Solberg, R.3    Andersson, K.B.4    Taylor, S.S.5    Lea, T.6
  • 30
    • 0017191695 scopus 로고
    • Adenosine 3':5'-cyclic monophosphate-binding proteins in bovine and rat tissues
    • Sugden PH, Corbin JD. Adenosine 3':5'-cyclic monophosphate-binding proteins in bovine and rat tissues. Biochem J 1976;159:423-427.
    • (1976) Biochem J , vol.159 , pp. 423-427
    • Sugden, P.H.1    Corbin, J.D.2
  • 31
    • 0017359323 scopus 로고
    • Concentrations of cyclic AMP-dependent protein kinase subunits in various tissues
    • Hofmann F, Bechtel PJ, Krebs EG. Concentrations of cyclic AMP-dependent protein kinase subunits in various tissues. J Biol Chem 1977;252(4):1441-1447.
    • (1977) J Biol Chem , vol.252 , Issue.4 , pp. 1441-1447
    • Hofmann, F.1    Bechtel, P.J.2    Krebs, E.G.3
  • 32
    • 0028009991 scopus 로고
    • Localization of A-kinase through anchoring proteins
    • Scott JD, McCartney S. Localization of A-kinase through anchoring proteins. Mol Endocrinol 1994;8:5-11.
    • (1994) Mol Endocrinol , vol.8 , pp. 5-11
    • Scott, J.D.1    McCartney, S.2
  • 33
    • 0025600922 scopus 로고
    • Dynamics of the distribution of cyclic AMP-dependent protein kinase in living cells
    • Meinkoth JL, Ji Y, Taylor SS, Feramisco JR. Dynamics of the distribution of cyclic AMP-dependent protein kinase in living cells. Proc Natl Acad Sci USA 1990;87:9595-9599.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 9595-9599
    • Meinkoth, J.L.1    Ji, Y.2    Taylor, S.S.3    Feramisco, J.R.4
  • 34
    • 0019837886 scopus 로고
    • A protein kinase bound to the projection portion of MAP 2 (microtubule-associated protein 2)
    • Vallee RB, DiBartolomeis MJ, Theurkauf WE. A protein kinase bound to the projection portion of MAP 2 (microtubule-associated protein 2). J Cell Biol 1981;90(3):568-576.
    • (1981) J Cell Biol , vol.90 , Issue.3 , pp. 568-576
    • Vallee, R.B.1    Dibartolomeis, M.J.2    Theurkauf, W.E.3
  • 35
    • 0035298062 scopus 로고    scopus 로고
    • Type i protein kinase a is localized to interphase microtubules and strongly associated with the mitotic spindle
    • Imaizumi-Scherrer T, Faust DM, Barradeau S, Hellio R, Weiss MC. Type I protein kinase a is localized to interphase microtubules and strongly associated with the mitotic spindle. Exp Cell Res 2001;264:250-265.
    • (2001) Exp Cell Res , vol.264 , pp. 250-265
    • Imaizumi-Scherrer, T.1    Faust, D.M.2    Barradeau, S.3    Hellio, R.4    Weiss, M.C.5
  • 36
    • 0345062221 scopus 로고    scopus 로고
    • Differential localization of protein kinase A type II isozymes in the Golgi-centrosomal area
    • Keryer G, Skalhegg BS, Landmark BF, Hansson V, Jahnsen T, Tasken K. Differential localization of protein kinase A type II isozymes in the Golgi-centrosomal area. Exp Cell Res 1999;249:131-146.
    • (1999) Exp Cell Res , vol.249 , pp. 131-146
    • Keryer, G.1    Skalhegg, B.S.2    Landmark, B.F.3    Hansson, V.4    Jahnsen, T.5    Tasken, K.6
  • 37
    • 0032545427 scopus 로고    scopus 로고
    • Mitosis-specific phosphorylation and subcellular redistribution of the RIIalpha regulatory subunit of cAMP-dependent protein kinase
    • Keryer G, Yassenko M, Labbe JC, Castro A, Lohmann SM, Evain-Brion D, et al. Mitosis-specific phosphorylation and subcellular redistribution of the RIIalpha regulatory subunit of cAMP-dependent protein kinase. J Biol Chem 1998;273:34, 594-34, 602.
    • (1998) J Biol Chem , vol.273 , pp. 34594-34602
    • Keryer, G.1    Yassenko, M.2    Labbe, J.C.3    Castro, A.4    Lohmann, S.M.5    Evain-Brion, D.6
  • 38
    • 0034773068 scopus 로고    scopus 로고
    • CDK1-mediated phosphorylation of the RIIalpha regulatory subunit of PKA works as a molecular switch that promotes dissociation of RIIalpha from centrosomes at mitosis
    • Carlson CR, Witczak O, Vossebein L, et al. CDK1-mediated phosphorylation of the RIIalpha regulatory subunit of PKA works as a molecular switch that promotes dissociation of RIIalpha from centrosomes at mitosis. J Cell Sci 2001;114:3243-3254.
    • (2001) J Cell Sci , vol.114 , pp. 3243-3254
    • Carlson, C.R.1    Witczak, O.2    Vossebein, L.3
  • 39
    • 0031855119 scopus 로고    scopus 로고
    • Subcellular distribution of the R-subunits of cAMP-dependent protein kinase in LS-174T human colon carcinoma cells
    • Kondrashin AA, Nesterova MV, Cho-Chung YS. Subcellular distribution of the R-subunits of cAMP-dependent protein kinase in LS-174T human colon carcinoma cells. Biochem Mol Biol Int 1998;45:237-244.
    • (1998) Biochem Mol Biol Int , vol.45 , pp. 237-244
    • Kondrashin, A.A.1    Nesterova, M.V.2    Cho-Chung, Y.S.3
  • 40
    • 0033524426 scopus 로고    scopus 로고
    • Cyclic adenosine 3':5'-monophosphate-dependent protein kinase on the external surface of LS-174T human colon carcinoma cells
    • Kondrashin A, Nesterova M, Cho-Chung YS. Cyclic adenosine 3':5'-monophosphate-dependent protein kinase on the external surface of LS-174T human colon carcinoma cells. Biochemistry 1999;38:172-179.
    • (1999) Biochemistry , vol.38 , pp. 172-179
    • Kondrashin, A.1    Nesterova, M.2    Cho-Chung, Y.S.3
  • 41
    • 0023698956 scopus 로고
    • The catalytic subunit of cAMP-dependent protein kinase induces expression of genes containing cAMP-responsive enhancer elements
    • Riabowol KT, Fink JS, Gilman MZ, Walsh DA, Goodman RH, Feramisco JR. The catalytic subunit of cAMP-dependent protein kinase induces expression of genes containing cAMP-responsive enhancer elements. Nature 1988;336:83-86.
    • (1988) Nature , vol.336 , pp. 83-86
    • Riabowol, K.T.1    Fink, J.S.2    Gilman, M.Z.3    Walsh, D.A.4    Goodman, R.H.5    Feramisco, J.R.6
  • 42
    • 0028124833 scopus 로고
    • Human regulatory subunit RI beta of cAMP-dependent protein kinases: Expression, holoenzyme formation and microinjection into living cells
    • Solberg R, Tasken K, Wen W, et al. Human regulatory subunit RI beta of cAMP-dependent protein kinases: expression, holoenzyme formation and microinjection into living cells. Exp Cell Res 1994;214:595-605.
    • (1994) Exp Cell Res , vol.214 , pp. 595-605
    • Solberg, R.1    Tasken, K.2    Wen, W.3
  • 43
    • 85047698859 scopus 로고    scopus 로고
    • Nuclear translocation of the catalytic subunit of protein kinase A induced by an antisense oligonucleotide directed against the RIalpha regulatory subunit
    • Neary CL, Cho-Chung YS. Nuclear translocation of the catalytic subunit of protein kinase A induced by an antisense oligonucleotide directed against the RIalpha regulatory subunit. Oncogene 2001;20:8019-8024.
    • (2001) Oncogene , vol.20 , pp. 8019-8024
    • Neary, C.L.1    Cho-Chung, Y.S.2
  • 45
    • 84900926414 scopus 로고
    • Binding of a holoenzyme and cAMP-dependent protein kinase subunits with cell nuclei
    • Aprikian AG, Nesterova MV, Glukhov AI, Severin ES. Binding of a holoenzyme and cAMP-dependent protein kinase subunits with cell nuclei. Biochemistry (NY)1987;52: 1118-1124.
    • (1987) Biochemistry (NY) , vol.52 , pp. 1118-1124
    • Aprikian, A.G.1    Nesterova, M.V.2    Glukhov, A.I.3    Severin, E.S.4
  • 46
    • 0021176602 scopus 로고
    • Nucleolar accumulation of cyclic adenosine 3':5'-monophosphate receptor proteins during regression of MCF-7 human breast tumor
    • Kapoor CL, Grantham F, Cho-Chung YS. Nucleolar accumulation of cyclic adenosine 3':5'-monophosphate receptor proteins during regression of MCF-7 human breast tumor. Cancer Res 1984;44:3554-3560.
    • (1984) Cancer Res , vol.44 , pp. 3554-3560
    • Kapoor, C.L.1    Grantham, F.2    Cho-Chung, Y.S.3
  • 47
    • 5644281831 scopus 로고    scopus 로고
    • Diamond I. cAMP-dependent protein kinase type i regulates ethanol-induced cAMP response element-mediated gene expression via activation of CREB-binding protein and inhibition of MAPK
    • Constantinescu A, Wu M, Asher O, Diamond I. cAMP-dependent protein kinase type I regulates ethanol-induced cAMP response element-mediated gene expression via activation of CREB-binding protein and inhibition of MAPK. J Biol Chem 2004;279: 43, 321-43, 329.
    • (2004) J Biol Chem , vol.279 , pp. 43321-43329
    • Constantinescu, A.1    Wu, M.2    Asher, O.3
  • 48
    • 9944245504 scopus 로고    scopus 로고
    • Protein kinase A isozyme switching: Eliciting differential cAMP signaling and tumor reversion
    • Neary CL, Nesterova M, Cho YS, Cheadle C, Becker KG, Cho-Chung YS. Protein kinase A isozyme switching: eliciting differential cAMP signaling and tumor reversion. Oncogene 2004;23:8847-8856.
    • (2004) Oncogene , vol.23 , pp. 8847-8856
    • Neary, C.L.1    Nesterova, M.2    Cho, Y.S.3    Cheadle, C.4    Becker, K.G.5    Cho-Chung, Y.S.6
  • 49
    • 10144233449 scopus 로고    scopus 로고
    • The v-Ki-Ras oncogene alters cAMP nuclear signaling by regulating the location and the expression of cAMP-dependent protein kinase II
    • Feliciello A, Giuliano P, Porcellini A, et al. The v-Ki-Ras oncogene alters cAMP nuclear signaling by regulating the location and the expression of cAMP-dependent protein kinase II(3. J Biol Chem 1996; 271:25, 350-25, 359.
    • (1996) J Biol Chem , vol.271 , pp. 25350-25359
    • Feliciello, A.1    Giuliano, P.2    Porcellini, A.3
  • 50
    • 0018777964 scopus 로고
    • Independent expression of cardiac type i and II cyclic AMP-dependent protein kinase during murine embryogenesis and postnatal development
    • Haddox MK, Roeske WR, Russell DH. Independent expression of cardiac type I and II cyclic AMP-dependent protein kinase during murine embryogenesis and postnatal development. Biochim Biophys Acta 1979;585:527-534.
    • (1979) Biochim Biophys Acta , vol.585 , pp. 527-534
    • Haddox, M.K.1    Roeske, W.R.2    Russell, D.H.3
  • 51
    • 0018010043 scopus 로고
    • Ontogenetic studies of cyclic AMP-dependent protein kinase enzymes from mouse heart and other tissues
    • Malkinson AM, Hogy L, Gharrett AJ, Gunderson TJ. Ontogenetic studies of cyclic AMP-dependent protein kinase enzymes from mouse heart and other tissues. J Exp Zool 1978; 205:423-431.
    • (1978) J Exp Zool , vol.205 , pp. 423-431
    • Malkinson, A.M.1    Hogy, L.2    Gharrett, A.J.3    Gunderson, T.J.4
  • 52
    • 0016761876 scopus 로고
    • Biochemical aspects of cardiac muscle differentiation. Deoxyribonucleic acid synthesis and nuclear and cytoplasmic deoxyribonucleic acid polymerase activity
    • Claycomb WC. Biochemical aspects of cardiac muscle differentiation. Deoxyribonucleic acid synthesis and nuclear and cytoplasmic deoxyribonucleic acid polymerase activity. J Biol Chem 1975;250:3229-3235.
    • (1975) J Biol Chem , vol.250 , pp. 3229-3235
    • Claycomb, W.C.1
  • 53
    • 0020163456 scopus 로고
    • Enhancement and desensitization of hormone-responsive adenylate cyclase in granulosa cells of preantral and antral ovarian follicles: Effects of estradiol and follicle-stimulating hormone
    • Jonassen JA, Bose K, Richards JS. Enhancement and desensitization of hormone-responsive adenylate cyclase in granulosa cells of preantral and antral ovarian follicles: effects of estradiol and follicle-stimulating hormone. Endocrinology 1982;111:74-79.
    • (1982) Endocrinology , vol.111 , pp. 74-79
    • Jonassen, J.A.1    Bose, K.2    Richards, J.S.3
  • 54
    • 0017887679 scopus 로고
    • Specific regulation by steroid hormones of the amount of type i cyclic AMP-dependent protein kinase holoenzyme
    • Fuller DJ, Byus CV, Russell DH. Specific regulation by steroid hormones of the amount of type I cyclic AMP-dependent protein kinase holoenzyme. Proc Natl Acad Sci USA 1978; 75:223-227.
    • (1978) Proc Natl Acad Sci USA , vol.75 , pp. 223-227
    • Fuller, D.J.1    Byus, C.V.2    Russell, D.H.3
  • 55
    • 0017161335 scopus 로고
    • Cell cycle-specific activity of type i and type II cyclic adenosine 3':5'-monophosphate-dependent protein kinases in Chinese hamster ovary cells
    • Costa M, Gerner EW, Russell DH. Cell cycle-specific activity of type I and type II cyclic adenosine 3':5'-monophosphate-dependent protein kinases in Chinese hamster ovary cells. J Biol Chem 1976;251(11):3313-3319.
    • (1976) J Biol Chem , vol.251 , Issue.11 , pp. 3313-3319
    • Costa, M.1    Gerner, E.W.2    Russell, D.H.3
  • 56
    • 0017394403 scopus 로고
    • Type i and type II cyclic AMP-dependent protein kinase as opposite effectors of lymphocyte mitogenesis
    • Byus CV, Klimpel GR, Lucas DO, Russell DH. Type I and type II cyclic AMP-dependent protein kinase as opposite effectors of lymphocyte mitogenesis. Nature 1977;268:63-64.
    • (1977) Nature , vol.268 , pp. 63-64
    • Byus, C.V.1    Klimpel, G.R.2    Lucas, D.O.3    Russell, D.H.4
  • 57
    • 0023938335 scopus 로고
    • The adenylate cyclase-cAMP-protein kinase A pathway and regulation of the immune response
    • Kammer GM. The adenylate cyclase-cAMP-protein kinase A pathway and regulation of the immune response. Immunol Today 1988;9:222-229.
    • (1988) Immunol Today , vol.9 , pp. 222-229
    • Kammer, G.M.1
  • 58
    • 0030070366 scopus 로고    scopus 로고
    • Activation of type i protein kinase A during receptor-mediated human T lymphocyte activation
    • Laxminarayana D, Kammer GM. Activation of type I protein kinase A during receptor-mediated human T lymphocyte activation. J Immunol 1996;156:497-506.
    • (1996) J Immunol , vol.156 , pp. 497-506
    • Laxminarayana, D.1    Kammer, G.M.2
  • 59
    • 0026736043 scopus 로고
    • Cyclic AMP-dependent protein kinase type i mediates the inhibitory effects of 3', 5'-cyclic adenosine monophosphate on cell replication in human T lymphocytes
    • Skalhegg BS, Landmark BF, Doskeland SO, Hansson V, Lea T, Jahnsen T. Cyclic AMP-dependent protein kinase type I mediates the inhibitory effects of 3', 5'-cyclic adenosine monophosphate on cell replication in human T lymphocytes. J Biol Chem 1992;267: 15, 707-15, 714.
    • (1992) J Biol Chem , vol.267 , pp. 15707-15714
    • Skalhegg, B.S.1    Landmark, B.F.2    Doskeland, S.O.3    Hansson, V.4    Lea, T.5    Jahnsen, T.6
  • 60
    • 0027993231 scopus 로고
    • Regulation of growth in a neoplastic B cell line by transfected subunits of 3', 5'-cyclic adenosine monophosphate-dependent protein kinase
    • Tasken K, Andersson KB, Erikstein BK, Hansson V, Jahnsen T, Blomhoff HK. Regulation of growth in a neoplastic B cell line by transfected subunits of 3', 5'-cyclic adenosine monophosphate-dependent protein kinase. Endocrinology 1994;135:2109-2119.
    • (1994) Endocrinology , vol.135 , pp. 2109-2119
    • Tasken, K.1    Andersson, K.B.2    Erikstein, B.K.3    Hansson, V.4    Jahnsen, T.5    Blomhoff, H.K.6
  • 61
    • 0020692011 scopus 로고
    • Regulation of cAMP-dependent protein kinase subunit levels in Friend erythroleukemic cells
    • Schwartz DA, Rubin CS. Regulation of cAMP-dependent protein kinase subunit levels in Friend erythroleukemic cells. J Biol Chem 1983;258:777-784.
    • (1983) J Biol Chem , vol.258 , pp. 777-784
    • Schwartz, D.A.1    Rubin, C.S.2
  • 62
    • 0018948184 scopus 로고
    • Hormonal induction of differentiation in teratocarcinoma stem cells: Generation of parietal endoderm by retinoic acid and dibutyryl cAMP
    • Strickland S, Smith KK, Marotti KR. Hormonal induction of differentiation in teratocarcinoma stem cells: generation of parietal endoderm by retinoic acid and dibutyryl cAMP Cell 1980;21:347-355.
    • (1980) Cell , vol.21 , pp. 347-355
    • Strickland, S.1    Smith, K.K.2    Marotti, K.R.3
  • 63
    • 0020027315 scopus 로고
    • Effect of retinoic acid treatment of F9 embryonal carcinoma cells on the activity and distribution of cyclic AMP-dependent protein kinase
    • Plet A, Evain D, Anderson WB. Effect of retinoic acid treatment of F9 embryonal carcinoma cells on the activity and distribution of cyclic AMP-dependent protein kinase. J Biol Chem 1982;257:889-893.
    • (1982) J Biol Chem , vol.257 , pp. 889-893
    • Plet, A.1    Evain, D.2    Anderson, W.B.3
  • 64
    • 0020664891 scopus 로고
    • Calcitonin effects on growth and on selective activation of type II isoenzyme of cyclic adenosine 3':5'-monophosphate-dependent protein kinase in T 47D human breast cancer cells
    • Ng KW, Livesey SA, Larkins RG, Martin TJ. Calcitonin effects on growth and on selective activation of type II isoenzyme of cyclic adenosine 3':5'-monophosphate-dependent protein kinase in T 47D human breast cancer cells. Cancer Res 1983;43:794-800.
    • (1983) Cancer Res , vol.43 , pp. 794-800
    • Ng, K.W.1    Livesey, S.A.2    Larkins, R.G.3    Martin, T.J.4
  • 65
    • 0019120386 scopus 로고
    • Hypothesis: Cyclic AMP and its receptor protein in tumor growth regulation in vivo
    • Cho-Chung YS. Hypothesis: cyclic AMP and its receptor protein in tumor growth regulation in vivo. J Cyclic Nucl Res 1980;6:163-177.
    • (1980) J Cyclic Nucl Res , vol.6 , pp. 163-177
    • Cho-Chung, Y.S.1
  • 66
    • 0017796062 scopus 로고
    • Type i cyclic AMP-dependent protein kinase as a positive effector of growth
    • Russell DH. Type I cyclic AMP-dependent protein kinase as a positive effector of growth. Adv Cycl Nucl Res 1978;9:493-506.
    • (1978) Adv Cycl Nucl Res , vol.9 , pp. 493-506
    • Russell, D.H.1
  • 67
    • 0023229550 scopus 로고
    • Site-selective cyclic AMP analogs provide a new approach in the control of cancer cell growth
    • Katsaros D, Tortora G, Tagliaferri P, et al. Site-selective cyclic AMP analogs provide a new approach in the control of cancer cell growth. FEBS Lett 1987;223:97-103
    • (1987) FEBS Lett , vol.223 , pp. 97-103
    • Katsaros, D.1    Tortora, G.2    Tagliaferri, P.3
  • 68
    • 0024415774 scopus 로고
    • Site-selective cyclic AMP analogs as new biological tools in growth control, differentiation and proto-oncogene regulation
    • Cho-Chung YS, Clair T, Tagliaferri P, et al. Site-selective cyclic AMP analogs as new biological tools in growth control, differentiation and proto-oncogene regulation. Cancer Inv 1989;7:161-177.
    • (1989) Cancer Inv , vol.7 , pp. 161-177
    • Cho-Chung, Y.S.1    Clair, T.2    Tagliaferri, P.3
  • 69
    • 0018894045 scopus 로고
    • Cyclic AMP-dependent protein kinase type i and type II and cyclic AMP binding in human mammary tumours
    • Eppenberger U, Briedermann K, Handshin JC, et al. Cyclic AMP-dependent protein kinase type I and type II and cyclic AMP binding in human mammary tumours. Adv Cyclic Nucleotide Res 1980;12:123-128.
    • (1980) Adv Cyclic Nucleotide Res , vol.12 , pp. 123-128
    • Eppenberger, U.1    Briedermann, K.2    Handshin, J.C.3
  • 70
    • 0023904197 scopus 로고
    • Site-selective cyclic AMP analogues are antagonistic to estrogen stimulation of growth and proto-oncogene expression in human breast-cancer cells
    • Katsaros D, Ally S, Cho-Chung YS. Site-selective cyclic AMP analogues are antagonistic to estrogen stimulation of growth and proto-oncogene expression in human breast-cancer cells. Int J Cancer 1988;41:863-867.
    • (1988) Int J Cancer , vol.41 , pp. 863-867
    • Katsaros, D.1    Ally, S.2    Cho-Chung, Y.S.3
  • 71
    • 0036297976 scopus 로고    scopus 로고
    • Regulatory subunits of PKA and breast cancer
    • Miller WR. Regulatory subunits of PKA and breast cancer. Ann NY Acad Sci 2002;968: 37-48.
    • (2002) Ann NY Acad Sci , vol.968 , pp. 37-48
    • Miller, W.R.1
  • 72
    • 0018181161 scopus 로고
    • Protein kinases in human renal cell carcinoma and renal cortex. A comparison of isozyme distribution and of responsiveness to adenosine 3':5'-cyclic monophosphate
    • Fossberg TM, Doskeland SO, Ueland PM. Protein kinases in human renal cell carcinoma and renal cortex. A comparison of isozyme distribution and of responsiveness to adenosine 3':5'-cyclic monophosphate. Arch Biochem Biophys 1978;189:372-381.
    • (1978) Arch Biochem Biophys , vol.189 , pp. 372-381
    • Fossberg, T.M.1    Doskeland, S.O.2    Ueland, P.M.3
  • 73
    • 0021687564 scopus 로고
    • Distribution and properties of type i and type II binding proteins in the Wilms' tumors
    • Nakajima F, Imashuku S, Wilimas J, Champion JE, Green AA. Distribution and properties of type I and type II binding proteins in the Wilms' tumors. Cancer Res 1984;44: 5182-5187.
    • (1984) Cancer Res , vol.44 , pp. 5182-5187
    • Nakajima, F.1    Imashuku, S.2    Wilimas, J.3    Champion, J.E.4    Green, A.A.5
  • 74
    • 0006931010 scopus 로고
    • Overexpressed type i regulatory subunit (RI) of cAMP-dependent protein kinase (PKA) as tumor marker in colorectal cancer
    • Bradbury AW, Miller WR, Clair T, Yokozaki H, Cho-Chung YS. Overexpressed type I regulatory subunit (RI) of cAMP-dependent protein kinase (PKA) as tumor marker in colorectal cancer. Proc Am Assoc Cancer Res 1990;31:172.
    • (1990) Proc Am Assoc Cancer Res , vol.31 , pp. 172
    • Bradbury, A.W.1    Miller, W.R.2    Clair, T.3    Yokozaki, H.4    Cho-Chung, Y.S.5
  • 77
    • 0020680934 scopus 로고
    • Cyclic adenosine3':5'-monophosphate-dependent and-independent protein kinases in human leukemic cells
    • Pena JM, Itarte E, Domingo A, Cusso R. Cyclic adenosine3':5'- monophosphate-dependent and-independent protein kinases in human leukemic cells. Cancer Res 1983;43:1172-1175.
    • (1983) Cancer Res , vol.43 , pp. 1172-1175
    • Pena, J.M.1    Itarte, E.2    Domingo, A.3    Cusso, R.4
  • 78
    • 0019774918 scopus 로고
    • CAMP receptor proteins and protein kinases in human lymphocytes: Fundamental alterations in chronic lymphocytic leukemia cells
    • Weber W, Schwoch G, Wielckens K, Gartemann A, Hilz H. cAMP receptor proteins and protein kinases in human lymphocytes: fundamental alterations in chronic lymphocytic leukemia cells. Eur J Biochem 1981;120:585-592.
    • (1981) Eur J Biochem , vol.120 , pp. 585-592
    • Weber, W.1    Schwoch, G.2    Wielckens, K.3    Gartemann, A.4    Hilz, H.5
  • 79
    • 0020770460 scopus 로고
    • Anticarcinogenic effect of M5, 02-dibutyryl cyclic adenosine 3', 5'-monophosphate on 7, 12-dimethylbenz(a) anthracene mammary tumor induction in the rat and its relationship to cyclic adenosine 3', 5'-monophosphate metabolism and protein kinase
    • Cho-Chung YS, Clair T, Shepheard C. Anticarcinogenic effect of M5, 02-dibutyryl cyclic adenosine 3', 5'-monophosphate on 7, 12-dimethylbenz(a) anthracene mammary tumor induction in the rat and its relationship to cyclic adenosine 3', 5'-monophosphate metabolism and protein kinase. Cancer Res 1983;43:2736-2740.
    • (1983) Cancer Res , vol.43 , pp. 2736-2740
    • Cho-Chung, Y.S.1    Clair, T.2    Shepheard, C.3
  • 80
    • 0022411720 scopus 로고
    • Effect of gastrin on gastric mucosal cyclic adenosine 3', 5'-monophos-phate-dependent protein kinase activity in rat stomach carcinogenesis induced by A-methyl-A-nitro-A-nitrosoguanidine
    • Yasui W, Tahara E. Effect of gastrin on gastric mucosal cyclic adenosine 3', 5'-monophos-phate-dependent protein kinase activity in rat stomach carcinogenesis induced by A-methyl-A-nitro-A-nitrosoguanidine. Cancer Res 1985;45:4763-4767.
    • (1985) Cancer Res , vol.45 , pp. 4763-4767
    • Yasui, W.1    Tahara, E.2
  • 81
    • 0022004422 scopus 로고
    • Changes in cyclic adenosine 3':5'-monophosphate-dependent protein kinases during the progression of ure-than-induced mouse lung tumors
    • Butley MS, Stoner GD, Beer DG, Beer DS, Mason RJ, Malkinson AM. Changes in cyclic adenosine 3':5'-monophosphate-dependent protein kinases during the progression of ure-than-induced mouse lung tumors. Cancer Res 1985;45:3677-3685.
    • (1985) Cancer Res , vol.45 , pp. 3677-3685
    • Butley, M.S.1    Stoner, G.D.2    Beer, D.G.3    Beer, D.S.4    Mason, R.J.5    Malkinson, A.M.6
  • 82
    • 0025343819 scopus 로고
    • Decreased expression of the type i isozyme of cAMP-dependent protein kinase in tumor cell lines of lung epithelial origin
    • Lange-Carter CA, Fossli T, Jahnsen T, Malkinson AM. Decreased expression of the type I isozyme of cAMP-dependent protein kinase in tumor cell lines of lung epithelial origin. J Biol Chem 1990;265:7814-7818.
    • (1990) J Biol Chem , vol.265 , pp. 7814-7818
    • Lange-Carter, C.A.1    Fossli, T.2    Jahnsen, T.3    Malkinson, A.M.4
  • 83
    • 0019401983 scopus 로고
    • Cyclic AMP-dependent protein kinases from Balb 3T3 cells and other 3T3 derived lines
    • Wehner JM, Malkinson AM, Wiser MF, Sheppard JR. Cyclic AMP-dependent protein kinases from Balb 3T3 cells and other 3T3 derived lines. J Cell Physiol 1981;108:175-184.
    • (1981) J Cell Physiol , vol.108 , pp. 175-184
    • Wehner, J.M.1    Malkinson, A.M.2    Wiser, M.F.3    Sheppard, J.R.4
  • 84
    • 0021167659 scopus 로고
    • Increase in type i cyclic adenosine 3':5'-monophosphate-dependent protein kinase activity and specific accumulation of type i regulatory subunits in adenovirus type 12-transformed cells
    • Ledinko N, Chan IJ. Increase in type I cyclic adenosine 3':5'-monophosphate-dependent protein kinase activity and specific accumulation of type I regulatory subunits in adenovirus type 12-transformed cells. Cancer Res 1984;44:2622-2627.
    • (1984) Cancer Res , vol.44 , pp. 2622-2627
    • Ledinko, N.1    Chan, I.J.2
  • 85
    • 0023880224 scopus 로고
    • Reverse transformation of Harvey murine sarcoma virus-transformed NIH/3T3 cells by site-selective cyclic AMP analogs
    • Tagliaferri P, Katsaros D, Clair T, Neckers L, Robins RK, Cho-Chung YS. Reverse transformation of Harvey murine sarcoma virus-transformed NIH/3T3 cells by site-selective cyclic AMP analogs. J Biol Chem 1988;263:409-416.
    • (1988) J Biol Chem , vol.263 , pp. 409-416
    • Tagliaferri, P.1    Katsaros, D.2    Clair, T.3    Neckers, L.4    Robins, R.K.5    Cho-Chung, Y.S.6
  • 86
    • 0024532120 scopus 로고
    • Site-selective 8-chloroadenosine 3', 5'-cyclic monophosphate inhibits transformation and transforming growth factor alpha production in Ki-ras-transformed rat fibroblasts
    • Tortora G, Ciardiello F, Ally S, Clair T, Salomon DS, Cho-Chung YS. Site-selective 8-chloroadenosine 3', 5'-cyclic monophosphate inhibits transformation and transforming growth factor alpha production in Ki-ras-transformed rat fibroblasts. FEBS Lett 1989;242: 363-367.
    • (1989) FEBS Lett , vol.242 , pp. 363-367
    • Tortora, G.1    Ciardiello, F.2    Ally, S.3    Clair, T.4    Salomon, D.S.5    Cho-Chung, Y.S.6
  • 87
    • 0025070111 scopus 로고
    • 8-chloro-cAMP inhibits transforming growth factor a transformation of mammary epithelial cells by restoration of the normal mRNA patterns for cAMP-dependent protein kinase regulatory subunit isoforms which show disruption upon transformation
    • Ciardiello F, Tortora G, Kim N, et al. 8-chloro-cAMP inhibits transforming growth factor a transformation of mammary epithelial cells by restoration of the normal mRNA patterns for cAMP-dependent protein kinase regulatory subunit isoforms which show disruption upon transformation. J Biol Chem 1990;265:1016-1020.
    • (1990) J Biol Chem , vol.265 , pp. 1016-1020
    • Ciardiello, F.1    Tortora, G.2    Kim, N.3
  • 88
    • 0023714205 scopus 로고
    • Selective modulation of protein kinase isozymes by the site-selective analog 8-chloroadenosine 3', 5'-cyclic monophosphate provides a biological means for control of human colon cancer cell growth
    • Ally S, Tortora G, Clair T, et al. Selective modulation of protein kinase isozymes by the site-selective analog 8-chloroadenosine 3', 5'-cyclic monophosphate provides a biological means for control of human colon cancer cell growth. Proc Natl Acad Sci USA 1988;85: 6319-6322.
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 6319-6322
    • Ally, S.1    Tortora, G.2    Clair, T.3
  • 89
    • 0024418926 scopus 로고
    • Inhibition of growth and modulation of gene expression in human lung carcinoma in athymic mice by site-selective 8-Cl-cyclic adenosine monophosphate
    • Ally S, Clair T, Katsaros D, et al. Inhibition of growth and modulation of gene expression in human lung carcinoma in athymic mice by site-selective 8-Cl-cyclic adenosine monophosphate. Cancer Res 1989;49:5650-5655.
    • (1989) Cancer Res , vol.49 , pp. 5650-5655
    • Ally, S.1    Clair, T.2    Katsaros, D.3
  • 90
    • 0025980027 scopus 로고
    • Differentiation of HL-60 leukemia cells by type i regulatory subunit antisense oligodeoxynucleotide of cAMP-dependent protein kinase
    • Tortora G, Yokozaki H, Pepe S, Clair T, Cho-Chung YS. Differentiation of HL-60 leukemia cells by type I regulatory subunit antisense oligodeoxynucleotide of cAMP-dependent protein kinase. Proc Natl Acad Sci USA 1991;88:2011-2015.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 2011-2015
    • Tortora, G.1    Yokozaki, H.2    Pepe, S.3    Clair, T.4    Cho-Chung, Y.S.5
  • 91
    • 0027499174 scopus 로고
    • An antisense oligodeoxynucleotide that depletes RIa subunit of cyclic AMP-dependent protein kinase induces growth inhibition in human cancer cells
    • Yokozaki H, Budillon A, Tortora G, et al. An antisense oligodeoxynucleotide that depletes RIa subunit of cyclic AMP-dependent protein kinase induces growth inhibition in human cancer cells. Cancer Res 1993;53:868-872.
    • (1993) Cancer Res , vol.53 , pp. 868-872
    • Yokozaki, H.1    Budillon, A.2    Tortora, G.3
  • 92
    • 0025187865 scopus 로고
    • Type II regulatory subunit of protein kinase restores cAMP-dependent transcription in a cAMP-unresponsive cell line
    • Tortora G, Cho-Chung YS. Type II regulatory subunit of protein kinase restores cAMP-dependent transcription in a cAMP-unresponsive cell line. J Biol Chem 1990;265: 18, 067-18, 070.
    • (1990) J Biol Chem , vol.265 , pp. 18067-18070
    • Tortora, G.1    Cho-Chung, Y.S.2
  • 93
    • 25144453716 scopus 로고    scopus 로고
    • The Second Subunit of the Replication Factor C complex (RFC40) and the Regulatory Subunit (RIalpha) of Protein Kinase A Form a Protein Complex Promoting Cell Survival
    • Gupte RS, Weng Y, Liu L, Lee MY. The Second Subunit of the Replication Factor C complex (RFC40) and the Regulatory Subunit (RIalpha) of Protein Kinase A Form a Protein Complex Promoting Cell Survival. Cell Cycle 2005;4:323-329.
    • (2005) Cell Cycle , vol.4 , pp. 323-329
    • Gupte, R.S.1    Weng, Y.2    Liu, L.3    Lee, M.Y.4
  • 94
    • 11244328112 scopus 로고    scopus 로고
    • A conserved interaction between the replicative clamp loader and DNA ligase in eukaryotes: Implications for Okazaki fragment joining
    • Levin DS, Vijayakumar S, Liu X, Bermudez VP, Hurwitz J, Tomkinson AE. A conserved interaction between the replicative clamp loader and DNA ligase in eukaryotes: implications for Okazaki fragment joining. J Biol Chem 2004;279:55, 196-55, 201.
    • (2004) J Biol Chem , vol.279 , pp. 55196-55201
    • Levin, D.S.1    Vijayakumar, S.2    Liu, X.3    Bermudez, V.P.4    Hurwitz, J.5    Tomkinson, A.E.6
  • 95
  • 96
    • 0024348542 scopus 로고
    • The consequences of introducing an autophosphorylation site into the type i regulatory subunit of cAMP-dependent protein kinase
    • Durgerian S, Taylor SS. The consequences of introducing an autophosphorylation site into the type I regulatory subunit of cAMP-dependent protein kinase. J Biol Chem 1989;264: 9807-9813.
    • (1989) J Biol Chem , vol.264 , pp. 9807-9813
    • Durgerian, S.1    Taylor, S.S.2
  • 97
    • 0023947759 scopus 로고
    • Mutagenesis of the regulatory subunit of yeast cAMP-dependent protein kinase: Isolation of site-directed mutants with altered binding affinity for catalytic subunit
    • Kuret J, Johnson KE, Nicolette C, Zoller MJ. Mutagenesis of the regulatory subunit of yeast cAMP-dependent protein kinase: Isolation of site-directed mutants with altered binding affinity for catalytic subunit. J Biol Chem 1988;263:9149-9154.
    • (1988) J Biol Chem , vol.263 , pp. 9149-9154
    • Kuret, J.1    Johnson, K.E.2    Nicolette, C.3    Zoller, M.J.4
  • 98
    • 0029671412 scopus 로고    scopus 로고
    • Overexpression of RIIp regulatory subunit of protein kinase A in human colon carcinoma cell induces growth arrest and phenotypic changes that are abolished by site-directed mutation of RIIp
    • Nesterova MV, Yokozaki H, McDuffie L, Cho-Chung YS. Overexpression of RIIp regulatory subunit of protein kinase A in human colon carcinoma cell induces growth arrest and phenotypic changes that are abolished by site-directed mutation of RIIp. Eur J Biochem 1996;235:486-494.
    • (1996) Eur J Biochem , vol.235 , pp. 486-494
    • Nesterova, M.V.1    Yokozaki, H.2    McDuffie, L.3    Cho-Chung, Y.S.4
  • 99
    • 0032587221 scopus 로고    scopus 로고
    • Ala99ser mutation in RI alpha regulatory subunit of protein kinase A causes reduced kinase activation by cAMP and arrest of hormone-dependent breast cancer cell growth
    • Lee GR, Kim SN, Noguchi K, Park SD, Hong SH, Cho-Chung YS. Ala99ser mutation in RI alpha regulatory subunit of protein kinase A causes reduced kinase activation by cAMP and arrest of hormone-dependent breast cancer cell growth. Mol Cell Biochem 1999;195:77-86.
    • (1999) Mol Cell Biochem , vol.195 , pp. 77-86
    • Lee, G.R.1    Kim, S.N.2    Noguchi, K.3    Park, S.D.4    Hong, S.H.5    Cho-Chung, Y.S.6
  • 100
    • 0033812849 scopus 로고    scopus 로고
    • Mutations of the gene encoding the protein kinase A type I-alpha regulatory subunit in patients with the Carney complex
    • Kirschner LS, Carney JA, Pack SD, et al. Mutations of the gene encoding the protein kinase A type I-alpha regulatory subunit in patients with the Carney complex. Nat Genet 2000; 26: 89-92.
    • (2000) Nat Genet , vol.26 , pp. 89-92
    • Kirschner, L.S.1    Carney, J.A.2    Pack, S.D.3
  • 102
    • 10844257526 scopus 로고    scopus 로고
    • Down-regulation of regulatory subunit type 1A of protein kinase A leads to endocrine and other tumors
    • Griffin KJ, Kirschner LS, Matyakhina L, et al. Down-regulation of regulatory subunit type 1A of protein kinase A leads to endocrine and other tumors. Cancer Res 2004;64: 8811-8815.
    • (2004) Cancer Res , vol.64 , pp. 8811-8815
    • Griffin, K.J.1    Kirschner, L.S.2    Matyakhina, L.3
  • 103
    • 19944408615 scopus 로고    scopus 로고
    • A transgenic mouse bearing an antisense construct of regulatory subunit type 1A of protein kinase A develops endocrine and other tumours: Comparison with Carney complex and other PRKAR1A induced lesions
    • Griffin KJ, Kirschner LS, Matyakhina L, et al. A transgenic mouse bearing an antisense construct of regulatory subunit type 1A of protein kinase A develops endocrine and other tumours: comparison with Carney complex and other PRKAR1A induced lesions. J Med Genet 2004;41:923-931.
    • (2004) J Med Genet , vol.41 , pp. 923-931
    • Griffin, K.J.1    Kirschner, L.S.2    Matyakhina, L.3
  • 104
    • 10844227998 scopus 로고    scopus 로고
    • Proliferation of transformed somatotroph cells related to low or absent expression of protein kinase a regulatory subunit 1A protein
    • Lania AG, Mantovani G, Ferrero S, et al. Proliferation of transformed somatotroph cells related to low or absent expression of protein kinase a regulatory subunit 1A protein. Cancer Res 2004;64:9193-9198.
    • (2004) Cancer Res , vol.64 , pp. 9193-9198
    • Lania, A.G.1    Mantovani, G.2    Ferrero, S.3
  • 105
    • 0008318284 scopus 로고
    • Reduced adenyl cyclase activity in a polyomavirus transformed cell line
    • Burk RR. Reduced adenyl cyclase activity in a polyomavirus transformed cell line. Nature 1968;219:1272-1275.
    • (1968) Nature , vol.219 , pp. 1272-1275
    • Burk, R.R.1
  • 106
    • 0015011570 scopus 로고
    • Restoration of several morphological characteristics of normal fibroblasts in sarcoma cells treated with adenosine-3', 5'-cycle monophosphate and its derivatives
    • Johnson GS, Friedman RM, Pastan I. Restoration of several morphological characteristics of normal fibroblasts in sarcoma cells treated with adenosine-3', 5'-cycle monophosphate and its derivatives. Proc Natl Acad Sci USA 1971;68:425-429.
    • (1971) Proc Natl Acad Sci USA , vol.68 , pp. 425-429
    • Johnson, G.S.1    Friedman, R.M.2    Pastan, I.3
  • 107
    • 0015981412 scopus 로고
    • In vivo inhibition of growth of two hormone-dependent mammary tumors by dibutyryl cyclic AMP
    • Cho-Chung YS, Gullino PM. In vivo inhibition of growth of two hormone-dependent mammary tumors by dibutyryl cyclic AMP. Science 1974;183:87-88.
    • (1974) Science , vol.183 , pp. 87-88
    • Cho-Chung, Y.S.1    Gullino, P.M.2
  • 108
    • 0017828044 scopus 로고
    • Evidence that rabbit muscle protein kinase has two kinetically distinct binding sites for adenosine 3', 5'-cyclic monophosphate
    • Døskeland SO. Evidence that rabbit muscle protein kinase has two kinetically distinct binding sites for adenosine 3', 5'-cyclic monophosphate. Biochem Biophys Res Commun 1978;83:542-549.
    • (1978) Biochem Biophys Res Commun , vol.83 , pp. 542-549
    • Døskeland, S.O.1
  • 109
    • 0019321425 scopus 로고
    • Two different intrachain cAMP binding sites of cAMP-dependent protein kinases
    • Rannels SR, Corbin JD. Two different intrachain cAMP binding sites of cAMP-dependent protein kinases. J Biol Chem 1980;255:7085-7088.
    • (1980) J Biol Chem , vol.255 , pp. 7085-7088
    • Rannels, S.R.1    Corbin, J.D.2
  • 110
    • 0024353952 scopus 로고
    • Commentary: Site-selective 8-chloro-cyclic adenosine 3', 5'-monophos-phate as a biologic modulator of cancer: Restoration of normal control mechanisms
    • Cho-Chung YS. Commentary: site-selective 8-chloro-cyclic adenosine 3', 5'-monophos-phate as a biologic modulator of cancer: restoration of normal control mechanisms. J Natl Cancer Inst 1989;81:982-987.
    • (1989) J Natl Cancer Inst , vol.81 , pp. 982-987
    • Cho-Chung, Y.S.1
  • 111
    • 0021856608 scopus 로고
    • Activation of protein kinase isozymes by cyclic nucleotide analogs used singly or in combination. Principles for optimizing the isozyme specificity of analog combinations
    • Ogreid D, Ekanger R, Suva RH, et al. Activation of protein kinase isozymes by cyclic nucleotide analogs used singly or in combination. Principles for optimizing the isozyme specificity of analog combinations. Eur J Biochem 1985;150:219-227.
    • (1985) Eur J Biochem , vol.150 , pp. 219-227
    • Ogreid, D.1    Ekanger, R.2    Suva, R.H.3
  • 112
    • 0025222504 scopus 로고
    • Role of cyclic AMP receptor proteins in growth, differentiation, and suppression of malignancy: New approaches to therapy
    • Cho-Chung YS. Role of cyclic AMP receptor proteins in growth, differentiation, and suppression of malignancy: new approaches to therapy. Cancer Res 1990;50:7093-7100.
    • (1990) Cancer Res , vol.50 , pp. 7093-7100
    • Cho-Chung, Y.S.1
  • 113
    • 0032532354 scopus 로고    scopus 로고
    • 8Cl-cAMP cytotoxicity in both steroid sensitive and insensitive multiple myeloma cell lines is mediated by 8Cl-adenosine
    • Halgren RG, Traynor AE, Pillay S, et al. 8Cl-cAMP cytotoxicity in both steroid sensitive and insensitive multiple myeloma cell lines is mediated by 8Cl-adenosine. Blood 1998; 92:2893-2898.
    • (1998) Blood , vol.92 , pp. 2893-2898
    • Halgren, R.G.1    Traynor, A.E.2    Pillay, S.3
  • 114
    • 0023930781 scopus 로고
    • Synergistic inhibition of growth of breast and colon human cancer cell lines by site-selective cyclic AMP analogues
    • Tagliaferri P, Katsaros D, Clair T, et al. Synergistic inhibition of growth of breast and colon human cancer cell lines by site-selective cyclic AMP analogues. Cancer Res 1988;48: 1642-1650.
    • (1988) Cancer Res , vol.48 , pp. 1642-1650
    • Tagliaferri, P.1    Katsaros, D.2    Clair, T.3
  • 115
    • 0018852820 scopus 로고
    • Cytotoxic effects of two novel 8-substituted cyclic nucleotide derivaties in cultured rat hepatoma cells
    • Koontz JW, Wicks WD. Cytotoxic effects of two novel 8-substituted cyclic nucleotide derivaties in cultured rat hepatoma cells. Mol Pharmacol 1980;18:65-71.
    • (1980) Mol Pharmacol , vol.18 , pp. 65-71
    • Koontz, J.W.1    Wicks, W.D.2
  • 116
    • 0017331424 scopus 로고
    • Comparison of the effects of 6-thio-and 6-methylthiopurine ribonucleoside cyclic monophosphates with their corresponding nucleosides on the growth of rat hepatoma cells
    • Koontz JW, Wicks WD. Comparison of the effects of 6-thio-and 6-methylthiopurine ribonucleoside cyclic monophosphates with their corresponding nucleosides on the growth of rat hepatoma cells. Cancer Res 1977;37:651-657.
    • (1977) Cancer Res , vol.37 , pp. 651-657
    • Koontz, J.W.1    Wicks, W.D.2
  • 118
    • 2642667187 scopus 로고
    • Induction of megakaryocytic differentiation and modulation of protein kinase gene expression by site-selective cAMP analogs in K-562 human leukemic cells
    • Tortora G, Clair T, Katsaros D, et al. Induction of megakaryocytic differentiation and modulation of protein kinase gene expression by site-selective cAMP analogs in K-562 human leukemic cells. Proc Natl Acad Sci USA 1989;86:2849-2852.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 2849-2852
    • Tortora, G.1    Clair, T.2    Katsaros, D.3
  • 119
    • 0032783599 scopus 로고    scopus 로고
    • Synergistic effects of retinoic acid and 8-chloro-adenosine 3', 5'-cyclic monophosphate on the regulation of retinoic acid receptor beta and apoptosis: Involvement of mitochondria
    • Srivastava RK, Srivastava AR, Cho-Chung YS, Longo DL. Synergistic effects of retinoic acid and 8-chloro-adenosine 3', 5'-cyclic monophosphate on the regulation of retinoic acid receptor beta and apoptosis: involvement of mitochondria. Clin Cancer Res 1999;5: 1892-1904.
    • (1999) Clin Cancer Res , vol.5 , pp. 1892-1904
    • Srivastava, R.K.1    Srivastava, A.R.2    Cho-Chung, Y.S.3    Longo, D.L.4
  • 120
    • 0033894899 scopus 로고    scopus 로고
    • Dual anticancer activity of 8-Cl-cAMP: Inhibition of cell proliferation and induction of apoptotic cell death
    • Kim SN, Kim SG, Park JH, et al. Dual anticancer activity of 8-Cl-cAMP: inhibition of cell proliferation and induction of apoptotic cell death. Biochem Biophys Res Commun 2000; 273:404-410.
    • (2000) Biochem Biophys Res Commun , vol.273 , pp. 404-410
    • Kim, S.N.1    Kim, S.G.2    Park, J.H.3
  • 121
    • 0027456590 scopus 로고
    • 8-Cl-cAMP induces trancation and down-regulation of the RIa subunit and up-regulation of the RIIp subunit of cAMP-dependent protein kinase leading to type II holoenzyme-dependent growth inhibition and differentiation of HL-60 leukemia cells
    • Rohlff CT, Clair T, Cho-Chung YS. 8-Cl-cAMP induces trancation and down-regulation of the RIa subunit and up-regulation of the RIIp subunit of cAMP-dependent protein kinase leading to type II holoenzyme-dependent growth inhibition and differentiation of HL-60 leukemia cells. J Biol Chem 1993;268:5774-5782.
    • (1993) J Biol Chem , vol.268 , pp. 5774-5782
    • Rohlff, C.T.1    Clair, T.2    Cho-Chung, Y.S.3
  • 122
    • 0033120591 scopus 로고    scopus 로고
    • Phosphorylation and inactivation of BAD by mitochondria-anchored protein kinase A
    • Harada H, Becknell B, Wilm M, et al. Phosphorylation and inactivation of BAD by mitochondria-anchored protein kinase A. Mol Cell 1999;3:413-422.
    • (1999) Mol Cell , vol.3 , pp. 413-422
    • Harada, H.1    Becknell, B.2    Wilm, M.3
  • 123
    • 0026781533 scopus 로고
    • Inhibition of the self-renewal capacity of blast progenitors from acute myeloblastic leukemia patients by site-selective 8-chloroadenosine 3', 5'-cyclic monophosphate
    • Pinto A, Aldinucci D, Gattel V, et al. Inhibition of the self-renewal capacity of blast progenitors from acute myeloblastic leukemia patients by site-selective 8-chloroadenosine 3', 5'-cyclic monophosphate. Proc Natl Acad Sci USA 1992;89:8884-8888.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 8884-8888
    • Pinto, A.1    Aldinucci, D.2    Gattel, V.3
  • 124
    • 0028948435 scopus 로고
    • Phase i clinical study with 8-chloro-cAMP and evaluation of immunological effects in cancer patients
    • Tortora G, Ciardiello F, Pepe S, et al. Phase I clinical study with 8-chloro-cAMP and evaluation of immunological effects in cancer patients. Clin Cancer Res 1995;4:377-384.
    • (1995) Clin Cancer Res , vol.4 , pp. 377-384
    • Tortora, G.1    Ciardiello, F.2    Pepe, S.3
  • 125
    • 3342953979 scopus 로고    scopus 로고
    • Activation of protein kinase A (PKA by 8-Cl-cAMP as a novel approach for antileukaemic therapy
    • Weissinger EM, Oettrich K, Evans C, et al. Activation of protein kinase A (PKA by 8-Cl-cAMP as a novel approach for antileukaemic therapy. Br J Cancer 2004;91:186-192.
    • (2004) Br J Cancer , vol.91 , pp. 186-192
    • Weissinger, E.M.1    Oettrich, K.2    Evans, C.3
  • 126
    • 84900917806 scopus 로고
    • A RIa subunit antisense oligonucleotide of cAMP-dependent protein kinase inhibits proliferation of human HL-60 promyelocytic lekemia
    • Tortora G, Pepe S, Yokozaki H, Clair T, Rohlff C, Cho-Chung YS. A RIa subunit antisense oligonucleotide of cAMP-dependent protein kinase inhibits proliferation of human HL-60 promyelocytic lekemia. Proc Am Acssoc Cancer Res 1990;31:38.
    • (1990) Proc Am Acssoc Cancer Res , vol.31 , pp. 38
    • Tortora, G.1    Pepe, S.2    Yokozaki, H.3    Clair, T.4    Rohlff, C.5    Cho-Chung, Y.S.6
  • 127
    • 0025012835 scopus 로고
    • An antisense oligodeoxynucleotide targeted against the type RII beta regulatory subunit mRNA of protein kinase inhibits cAMP-induced differentiation in HL-60 leukemia cells without affecting phorbol ester effects
    • Tortora G, Clair T, Cho-Chung YS. An antisense oligodeoxynucleotide targeted against the type RII beta regulatory subunit mRNA of protein kinase inhibits cAMP-induced differentiation in HL-60 leukemia cells without affecting phorbol ester effects. Proc Natl Acad Sci USA 1990;87:705-708.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 705-708
    • Tortora, G.1    Clair, T.2    Cho-Chung, Y.S.3
  • 128
    • 0021880219 scopus 로고
    • Identification and differential expression of two forms of regulatory subunits (RII) of cAMP-dependent protein kinase II in Friend urythroleukemic cells
    • Schwartz DA, Rubin CS. Identification and differential expression of two forms of regulatory subunits (RII) of cAMP-dependent protein kinase II in Friend urythroleukemic cells. J Biol Chem 1985;260:6063-6296.
    • (1985) J Biol Chem , vol.260 , pp. 6063-6296
    • Schwartz, D.A.1    Rubin, C.S.2
  • 129
    • 0029050664 scopus 로고
    • A single-injection protein kinase A-directed antisense treatment to inhibit tumour growth
    • Nesterova M, Cho-Chung YS. A single-injection protein kinase A-directed antisense treatment to inhibit tumour growth. Nat Med 1995;1:528-633.
    • (1995) Nat Med , vol.1 , pp. 528-633
    • Nesterova, M.1    Cho-Chung, Y.S.2
  • 130
    • 0033623173 scopus 로고    scopus 로고
    • Compensatory stabilization of RIIp protein, cell cycle deregulation, and growth arrest in colon and prostate carcinoma cells by antisense-directed down-regulation of protein kinase A RIa protein
    • Nesterova M, Noguchi K, Park YG, Lee YN, Cho-Chung YS. Compensatory stabilization of RIIp protein, cell cycle deregulation, and growth arrest in colon and prostate carcinoma cells by antisense-directed down-regulation of protein kinase A RIa protein. Clin Cancer Res 2000;6:3434-3441.
    • (2000) Clin Cancer Res , vol.6 , pp. 3434-3441
    • Nesterova, M.1    Noguchi, K.2    Park, Y.G.3    Lee, Y.N.4    Cho-Chung, Y.S.5
  • 131
    • 0030909609 scopus 로고    scopus 로고
    • Mixed-backbone oligonucleotides as second generation antisense oligonucleotides: In vitro and in vivo studies
    • Agrawal S, Jiang Z, Zhao Q, et al. Mixed-backbone oligonucleotides as second generation antisense oligonucleotides: in vitro and in vivo studies. Proc Natl Acad Sci USA 1997;94: 2620-2625.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 2620-2625
    • Agrawal, S.1    Jiang, Z.2    Zhao, Q.3
  • 132
    • 20244380289 scopus 로고    scopus 로고
    • A safety and pharmacokinetic study of a mixed-backbone oligonucleotide (GEM 231) targeting the type i protein kinase A by two-hour infusions in patients with refractory solid tumors
    • Chen HX, Marshall JL, Ness E, Martin RR, Dvorchik B, Rizvi N, et al. A safety and pharmacokinetic study of a mixed-backbone oligonucleotide (GEM 231) targeting the type I protein kinase A by two-hour infusions in patients with refractory solid tumors. Clin Cancer Res 2000;6:1259-1266.
    • (2000) Clin Cancer Res , vol.6 , pp. 1259-1266
    • Chen, H.X.1    Marshall, J.L.2    Ness, E.3    Martin, R.R.4    Dvorchik, B.5    Rizvi, N.6
  • 133
    • 0031948835 scopus 로고    scopus 로고
    • Mixed backbone oligonucleotides: Improvement in oligonucleotide-induced toxicity in vivo
    • Agrawal S, Zhao Q. Mixed backbone oligonucleotides: improvement in oligonucleotide-induced toxicity in vivo. Antisense Nucleic Acid Drug Dev 1998;8:135-139.
    • (1998) Antisense Nucleic Acid Drug Dev , vol.8 , pp. 135-139
    • Agrawal, S.1    Zhao, Q.2
  • 135
    • 0028598284 scopus 로고
    • Study of antisense oligonucleotide phosphorothioates containing segments of oligodeoxynucleotides and 2'-O-methyloligoribonucleotides
    • Metelev V, Liszlewicz J, Agrawal S. Study of antisense oligonucleotide phosphorothioates containing segments of oligodeoxynucleotides and 2'-O-methyloligoribonucleotides. Bioorg Med Chem Lett 1994;4:2929-2934.
    • (1994) Bioorg Med Chem Lett , vol.4 , pp. 2929-2934
    • Metelev, V.1    Liszlewicz, J.2    Agrawal, S.3
  • 136
    • 0027168725 scopus 로고
    • Evaluation of 2'-modified oligonucleotides containing 2'-deoxygaps as antisense inhibitors of gene expression
    • Monia BP, Lesnik EA, Gonzalez C, Lima WF, McGee D, Guinosso CJ, et al. Evaluation of 2'-modified oligonucleotides containing 2'-deoxygaps as antisense inhibitors of gene expression. J Biol Chem 1993;268:14, 514-14, 522.
    • (1993) J Biol Chem , vol.268 , pp. 14514-14522
    • Monia, B.P.1    Lesnik, E.A.2    Gonzalez, C.3    Lima, W.F.4    McGee, D.5    Guinosso, C.J.6
  • 138
    • 0036297650 scopus 로고    scopus 로고
    • Ciardiello F Protein kinase A as target for novel integrated strategies of cancer therapy
    • Tortora G, Ciardiello F Protein kinase A as target for novel integrated strategies of cancer therapy. Ann NY Acad Sci 2002;968:139-147.
    • (2002) Ann NY Acad Sci , vol.968 , pp. 139-147
    • Tortora, G.1
  • 139
    • 0027499522 scopus 로고
    • Down-regulation of RIa subunit of cAMP-dependent protein kinase induces growth inhibition of human mammary epithelial cells transformed by c-Ha-ras and c-erbB-2 proto-oncogenes
    • Ciardiello F, Pepe S, Bianco C, et al. Down-regulation of RIa subunit of cAMP-dependent protein kinase induces growth inhibition of human mammary epithelial cells transformed by c-Ha-ras and c-erbB-2 proto-oncogenes. Int J Cancer 1993;53:438-443.
    • (1993) Int J Cancer , vol.53 , pp. 438-443
    • Ciardiello, F.1    Pepe, S.2    Bianco, C.3
  • 140
    • 0036177671 scopus 로고    scopus 로고
    • Cyclooxygenase-2: A therapeutic target
    • Turini ME, DuBois RN. Cyclooxygenase-2: a therapeutic target. Annu Rev Med 2002; 53: 35-57.
    • (2002) Annu Rev Med , vol.53 , pp. 35-57
    • Turini, M.E.1    Dubois, R.N.2
  • 141
    • 0031813790 scopus 로고    scopus 로고
    • Involvement of microtubules in the regulation of Bcl2 phosphorylation and apoptosis through cyclic AMP-dependent protein kinase
    • Srivastava RK, Srivastava AR, Korsmeyer SJ, Nesterova M, Cho-Chung YS, Longo DL. Involvement of microtubules in the regulation of Bcl2 phosphorylation and apoptosis through cyclic AMP-dependent protein kinase. Mol Cell Biol 1998;18:3509-3517.
    • (1998) Mol Cell Biol , vol.18 , pp. 3509-3517
    • Srivastava, R.K.1    Srivastava, A.R.2    Korsmeyer, S.J.3    Nesterova, M.4    Cho-Chung, Y.S.5    Longo, D.L.6
  • 142
    • 0033517254 scopus 로고    scopus 로고
    • Protein kinase A-Ialpha subunit-directed antisense inhibition of ovarian cancer cell growth: Crosstalk with tyrosine kinase signaling pathway
    • Alper O, Hacker NF, Cho-Chung YS. Protein kinase A-Ialpha subunit-directed antisense inhibition of ovarian cancer cell growth: crosstalk with tyrosine kinase signaling pathway. Oncogene 1999;18:4999-5004.
    • (1999) Oncogene , vol.18 , pp. 4999-5004
    • Alper, O.1    Hacker, N.F.2    Cho-Chung, Y.S.3
  • 144
    • 0030729721 scopus 로고    scopus 로고
    • Synergistic inhibition of human cancer cell growth by cytotoxic drugs and mixed backbone antisense oligonucleotide targeting protein kinase A
    • Tortora G, Caputo R, Damiano V, et al. Synergistic inhibition of human cancer cell growth by cytotoxic drugs and mixed backbone antisense oligonucleotide targeting protein kinase A. Proc Natl Acad Sci USA 1997;94:12, 586-12, 591.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 12586-12591
    • Tortora, G.1    Caputo, R.2    Damiano, V.3
  • 145
    • 0033598705 scopus 로고    scopus 로고
    • Antitumor activity and pharmacokinetics of a mixed-backbone antisense oligonucleotide targeted to the RIalpha subunit of protein kinase A after oral administration
    • Wang H, Cai Q, Zeng X, Yu D, Agrawal S, Zhang R. Antitumor activity and pharmacokinetics of a mixed-backbone antisense oligonucleotide targeted to the RIalpha subunit of protein kinase A after oral administration. Proc Natl Acad Sci USA 1999;96:13, 989-13, 994.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 13989-13994
    • Wang, H.1    Cai, Q.2    Zeng, X.3    Yu, D.4    Agrawal, S.5    Zhang, R.6
  • 146
    • 0034130453 scopus 로고    scopus 로고
    • Oral antisense that targets protein kinase A cooperates with taxol and inhibits tumor growth, angiogenesis, and growth factor production
    • Tortora G, Bianco R, Damiano V, et al. Oral antisense that targets protein kinase A cooperates with taxol and inhibits tumor growth, angiogenesis, and growth factor production. Clin Cancer Res 2000;6:2506-2512.
    • (2000) Clin Cancer Res , vol.6 , pp. 2506-2512
    • Tortora, G.1    Bianco, R.2    Damiano, V.3
  • 147
    • 0036653149 scopus 로고    scopus 로고
    • Antisense oligonucleotide targeted to RIalpha subunit of cAMP-dependent protein kinase (GEM231) enhances therapeutic effectiveness of cancer chemotherapeutic agent irinotecan in nude mice bearing human cancer xenografts: In vivo synergistic activity, pharmacokinetics and host toxicity
    • Wang H, Hang J, Shi Z, et al. Antisense oligonucleotide targeted to RIalpha subunit of cAMP-dependent protein kinase (GEM231) enhances therapeutic effectiveness of cancer chemotherapeutic agent irinotecan in nude mice bearing human cancer xenografts: in vivo synergistic activity, pharmacokinetics and host toxicity. Int J Oncol 2002;21:73-80.
    • (2002) Int J Oncol , vol.21 , pp. 73-80
    • Wang, H.1    Hang, J.2    Shi, Z.3
  • 148
    • 0030614954 scopus 로고    scopus 로고
    • The RIa subunit of protein kinase A (PKA) binds to Grb2 and allows PKA interaction with the activated EGF-receptor
    • Tortora G, Damiano V, Bianco C, et al. The RIa subunit of protein kinase A (PKA) binds to Grb2 and allows PKA interaction with the activated EGF-receptor. Oncogene 1997;14:923-928.
    • (1997) Oncogene , vol.14 , pp. 923-928
    • Tortora, G.1    Damiano, V.2    Bianco, C.3
  • 149
    • 0033816198 scopus 로고    scopus 로고
    • Targeting of epidermal growth factor receptor and protein kinase A: Molecular basis and therapeutic applications
    • Tortora G, Ciardiello F. Targeting of epidermal growth factor receptor and protein kinase A: molecular basis and therapeutic applications. Ann Oncol 2000;11:777-783.
    • (2000) Ann Oncol , vol.11 , pp. 777-783
    • Tortora, G.1    Ciardiello, F.2
  • 150
    • 0032491195 scopus 로고    scopus 로고
    • Novel function of the regulatory subunit of protein kinase A: Regulation of cytochrome c oxidase activity and cytochrome c release
    • Yang WL, Iacono L, Tang WM, Chin KV. Novel function of the regulatory subunit of protein kinase A: regulation of cytochrome c oxidase activity and cytochrome c release. Biochemistry 1998;37:14, 175-14, 180
    • (1998) Biochemistry , vol.37 , pp. 14175-14180
    • Yang, W.L.1    Iacono, L.2    Tang, W.M.3    Chin, K.V.4
  • 151
    • 0031595777 scopus 로고    scopus 로고
    • Antisense depletion of RIalpha subunit of protein kinase A induces apoptosis and growth arrest in human breast cancer cells
    • Srivastava RK, Srivastava AR, Park YG, Agrawal S, Cho-Chung YS. Antisense depletion of RIalpha subunit of protein kinase A induces apoptosis and growth arrest in human breast cancer cells. Breast Cancer Res Treat 1998;49:97-107.
    • (1998) Breast Cancer Res Treat , vol.49 , pp. 97-107
    • Srivastava, R.K.1    Srivastava, A.R.2    Park, Y.G.3    Agrawal, S.4    Cho-Chung, Y.S.5
  • 152
    • 0036188072 scopus 로고    scopus 로고
    • Protein kinase A RIa antisense inhibition of PC3M prostate cancer cell growth: Bcl-2 hyperphosphorylation, Bax up-regulation, and Bad- hypophosphorylation
    • Cho YS, Kim MK, Tan L, Srivastava R, Agrawal S, Cho-Chung YS. Protein kinase A RIa antisense inhibition of PC3M prostate cancer cell growth: Bcl-2 hyperphosphorylation, Bax up-regulation, and Bad-hypophosphorylation. Clin Cancer Res 2002;8:607-614.
    • (2002) Clin Cancer Res , vol.8 , pp. 607-614
    • Cho, Y.S.1    Kim, M.K.2    Tan, L.3    Srivastava, R.4    Agrawal, S.5    Cho-Chung, Y.S.6
  • 153
    • 0034886312 scopus 로고    scopus 로고
    • Combined blockade of protein kinase A and bcl-2 by antisense strategy induces apoptosis and inhibits tumor growth and angiogenesis
    • Tortora G, Caputo R, Damiano V, et al. Combined blockade of protein kinase A and bcl-2 by antisense strategy induces apoptosis and inhibits tumor growth and angiogenesis. Clin Cancer Res 2001;7:2537-2544.
    • (2001) Clin Cancer Res , vol.7 , pp. 2537-2544
    • Tortora, G.1    Caputo, R.2    Damiano, V.3
  • 154
    • 3042770595 scopus 로고    scopus 로고
    • Antisense protein kinase A RIalpha inhibits 7, 12-dimethyl-benz(a) anthracene-induction of mammary cancer: Blockade at the initial phase of carcinogenesis
    • Nesterova MV, Cho-Chung YS. Antisense protein kinase A RIalpha inhibits 7, 12-dimethyl-benz(a)anthracene-induction of mammary cancer: blockade at the initial phase of carcinogenesis. Clin Cancer Res 2004;10:4568-4577.
    • (2004) Clin Cancer Res , vol.10 , pp. 4568-4577
    • Nesterova, M.V.1    Cho-Chung, Y.S.2
  • 155
    • 0035430282 scopus 로고    scopus 로고
    • Transcriptional regulation by the phosphorylation-dependent factor CREB
    • Mayr B, Montminy M. Transcriptional regulation by the phosphorylation-dependent factor CREB. Nat Rev Mol Cell Biol 2001;2:599-609.
    • (2001) Nat Rev Mol Cell Biol , vol.2 , pp. 599-609
    • Mayr, B.1    Montminy, M.2
  • 156
    • 0038185273 scopus 로고    scopus 로고
    • Genome-wide analysis of CREB target genes reveals a core promoter requirement for cAMP responsiveness
    • Conkright MD, Guzman E, Flechner L, et al. Genome-wide analysis of CREB target genes reveals a core promoter requirement for cAMP responsiveness. Mol Cell 2003;11:1101-1108.
    • (2003) Mol Cell , vol.11 , pp. 1101-1108
    • Conkright, M.D.1    Guzman, E.2    Flechner, L.3
  • 157
    • 0023198109 scopus 로고
    • Binding of a nuclear protein to the cyclic-AMP response element of the somatostatin gene
    • Montminy MR, Bilezikjian LM. Binding of a nuclear protein to the cyclic-AMP response element of the somatostatin gene. Nature 1987;328:175-178.
    • (1987) Nature , vol.328 , pp. 175-178
    • Montminy, M.R.1    Bilezikjian, L.M.2
  • 159
    • 12144289990 scopus 로고    scopus 로고
    • A CRE and the region occupied by a protein induced by growth factors contribute to up-regulation of cyclin D1 expression in hepatocytes
    • Moriuchi A, Ido A, Nagata Y, et al. A CRE and the region occupied by a protein induced by growth factors contribute to up-regulation of cyclin D1 expression in hepatocytes. Biochem Biophys Res Commun 2003;300:415-421.
    • (2003) Biochem Biophys Res Commun , vol.300 , pp. 415-421
    • Moriuchi, A.1    Ido, A.2    Nagata, Y.3
  • 160
  • 161
    • 0037384070 scopus 로고    scopus 로고
    • Egr-1 induction in rat granulosa cells by follicle-stimulating hormone and luteinizing hormone: Combinatorial regulation by transcription factors cyclic adenosine 3', 5'-monophosphate regulatory element binding protein, serum response factor, sp1, and early growth response factor-1
    • Russell DL, Doyle KM, Gonzales-Robayna I, Pipaon C, Richards JS. Egr-1 induction in rat granulosa cells by follicle-stimulating hormone and luteinizing hormone: combinatorial regulation by transcription factors cyclic adenosine 3', 5'-monophosphate regulatory element binding protein, serum response factor, sp1, and early growth response factor-1. Mol Endocrinol 2003;17:520-533.
    • (2003) Mol Endocrinol , vol.17 , pp. 520-533
    • Russell, D.L.1    Doyle, K.M.2    Gonzales-Robayna, I.3    Pipaon, C.4    Richards, J.S.5
  • 162
    • 0001611720 scopus 로고    scopus 로고
    • Dual blockade of cyclic AMP response element (CRE)-and AP-1-directed transcription by CRE transcription factor decoy oligonucleotide: Gene-specific inhibition of tumor growth
    • Park YG, Nesterova M, Agrawal S, Cho-Chung YS. Dual blockade of cyclic AMP response element (CRE)-and AP-1-directed transcription by CRE transcription factor decoy oligonucleotide: Gene-specific inhibition of tumor growth. J Biol Chem 1999;274:1573-1580.
    • (1999) J Biol Chem , vol.274 , pp. 1573-1580
    • Park, Y.G.1    Nesterova, M.2    Agrawal, S.3    Cho-Chung, Y.S.4
  • 163
    • 0025096117 scopus 로고
    • Cyclic AMP response element binding proteins: A cornucopia of transcription factors
    • Habener JF. Cyclic AMP response element binding proteins: a cornucopia of transcription factors. Mol Endocrinol 1990;4:1087-1094.
    • (1990) Mol Endocrinol , vol.4 , pp. 1087-1094
    • Habener, J.F.1
  • 164
    • 0034811055 scopus 로고    scopus 로고
    • Reduction in cyclin D1/Cdk4/retinoblastoma protein signaling by CRE-decoy oligonucleotide
    • Park YG, Park S, Lim SO, et al. Reduction in cyclin D1/Cdk4/ retinoblastoma protein signaling by CRE-decoy oligonucleotide. Biochem Biophys Res Commun 2001;281:1213-1219.
    • (2001) Biochem Biophys Res Commun , vol.281 , pp. 1213-1219
    • Park, Y.G.1    Park, S.2    Lim, S.O.3
  • 165
    • 3042725531 scopus 로고    scopus 로고
    • The in vitro effects of CRE-decoy oligonucleotides in combination with conventional chemotherapy in colorectal cancer cell lines
    • Liu WM, Scott KA, Shahin S, Propper DJ. The in vitro effects of CRE-decoy oligonucleotides in combination with conventional chemotherapy in colorectal cancer cell lines. Eur J Biochem 2004;271(13):2773-2781.
    • (2004) Eur J Biochem , vol.271 , Issue.13 , pp. 2773-2781
    • Liu, W.M.1    Scott, K.A.2    Shahin, S.3    Propper, D.J.4
  • 166
    • 0004989201 scopus 로고    scopus 로고
    • Extracellular protein kinase A as a cancer biomarker: Its expression by tumor cells and reversal by a myristate-lacking Calpha and RIIbeta subunit overexpression
    • Cho YS, Park YG, Lee YN, et al. Extracellular protein kinase A as a cancer biomarker: its expression by tumor cells and reversal by a myristate-lacking Calpha and RIIbeta subunit overexpression. Proc Natl Acad Sci USA 2000;97:835-840.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 835-840
    • Cho, Y.S.1    Park, Y.G.2    Lee, Y.N.3
  • 167
    • 0034735986 scopus 로고    scopus 로고
    • Biochemical characterization of extracellular cAMP-dependent protein kinase as a tumor marker
    • Cho YS, Lee YN, Cho-Chung YS. Biochemical characterization of extracellular cAMP-dependent protein kinase as a tumor marker. Biochem Biophys Res Commun 2000;278: 679-684.
    • (2000) Biochem Biophys Res Commun , vol.278 , pp. 679-684
    • Cho, Y.S.1    Lee, Y.N.2    Cho-Chung, Y.S.3
  • 168
    • 0034130447 scopus 로고    scopus 로고
    • Extracellular catalytic subunit activity of the cAMP-dependent protein kinase in prostate cancer
    • Cvijic ME, Kita T, Shih W, DiPaola RS, Chin KV. Extracellular catalytic subunit activity of the cAMP-dependent protein kinase in prostate cancer. Clin Cancer Res 2000;6(6): 2309-2317.
    • (2000) Clin Cancer Res , vol.6 , Issue.6 , pp. 2309-2317
    • Cvijic, M.E.1    Kita, T.2    Shih, W.3    Dipaola, R.S.4    Chin, K.V.5
  • 169
    • 2442611898 scopus 로고    scopus 로고
    • Extracellular cAMP-dependent protein kinase (ECPKA) in melanoma
    • Kita T, Goydos J, Reitman E, et al. Extracellular cAMP-dependent protein kinase (ECPKA) in melanoma. Cancer Lett 2004;208:187-191.
    • (2004) Cancer Lett , vol.208 , pp. 187-191
    • Kita, T.1    Goydos, J.2    Reitman, E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.