Reduction in cyclin D1/Cdk4/retinoblastoma protein signaling by CRE-decoy oligonucleotide

Biochemical and Biophysical Research Communications

Volumn 281, Issue 5, 2001, Pages 1213-1219

  Park, Yun Gyu ^a   Park, Serkin ^a   Lim, Seoung Ok ^a   Lee, Moon Seop ^a   Ryu, Chong Kun ^a   Kim, Insun ^a   Cho Chung, Yoon S ^b  

^a Korea University College of Medicine   (South Korea)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

CRE decoy oligonucleotide; Cyclin D1; G1 phase arrest; Retinoblastoma protein; Tumor growth inhibition

Indexed keywords

CYCLIN D1; OLIGONUCLEOTIDE; PROTEIN P53; RETINOBLASTOMA PROTEIN; TRANSCRIPTION FACTOR;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CANCER INHIBITION; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CONTROLLED STUDY; DOWN REGULATION; GENE EXPRESSION REGULATION; GENE MUTATION; GENE OVEREXPRESSION; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TUMOR CELL CULTURE;

EID: 0034811055     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.2001.4521     Document Type: Article

References (29)

1. CREB: A stimulus-induced transcription factor activated by a diverse array of extracellular signals
2. Signaling routes to CREM and CREB: Plasticity in transcriptional activation
3. Dual blockade of cyclic AMP response element- (CRE) and AP-1-directed transcription by CRE-transcription factor decoy oligonucleotide. Gene-specific inhibition of tumor growth
4. CRE-transcription factor decoy oligonucleotide inhibition of MCF-7 breast cancer cells: Cross-talk with p53 signaling pathway
5. Cancer cell cycles
6. Coupling of the RAS-MAPK pathway to gene activation by RSK2, a growth factor-regulated CREB kinase
7. Nerve growth factor activates extracellular signal-regulated kinase and p38 mitogen-activated protein kinase pathways to stimulate CREB serine 133 phosphorylation
8. Rsk-2 activity is necessary for epidermal growth factor-induced phosphorylation of CREB protein and transcription of c-fos gene
9. Mitogen- and stress-activated protein kinase-1 (MSK1) is directly activated by MAPK and SAPK2/p38, and may mediate activation of CREB
10. The retinoblastoma protein and cell cycle control
11. Angiotensin II activation of cyclin D1-dependent kinase activity
12. Transforming p21ras mutants and c-Ets-2 activate the cyclin D1 promoter through distinguishable regions
13. Integration of Rac-dependent regulation of cyclin D1 transcription through a nuclear factor-kappaB-dependent pathway
14. Convergence of mitogenic signaling cascades from diverse classes of receptors at the cyclin D-cyclin-dependent kinase-pRb-controlled G1 checkpoint
15. Ras transformation results in an elevated level of cyclin D1 and acceleration of G1 progression in NIH 3T3 cells
16. Reduced skin tumor development in cyclin D1-deficient mice highlights the oncogenic ras pathway in vivo
17. Increased cell growth and tumorigenicity in human prostate LNCaP cells by overexpression to cyclin D1
18. Antisense to cyclin D1 inhibits the growth and tumorigenicity of human colon caacer cells
19. Cyclin D1 induction in breast cancer cells shortens G1 and is sufficient for cells arrested in G1 to complete the cell cycle
20. Induction of cyclin D1 by simian virus 40 small tumor antigen
21. pp60(v-src) induction of cyclin D1 requires collaborative interactions between the extracellular signal-regulated kinase, p38, and Jun kinase pathways. A role for cAMP response element-binding protein and activating transcription factor-2 in pp60(v-src) signaling in breast cancer cells
22. Cyclin D1 is required for transformation by activated Neu and is induced through an E2F-dependent signaling pathway
23. Cell proliferation kinetics of MCF-7 human mammary carcinoma cells in culture and effects of tamoxifen on exponentially growing and plateau-phase cells
24. Estrogen-induced activation of Cdk4 and Cdk2 during G1-S phase progression is accompanied by increased cyclin D1 expression and decreased cyclin-dependent kinase inhibitor association with cyclin E-Cdk2
25. Estrogen induction of the cyclin D1 promoter: Involvement of a cAMP response-like element
26. A dominant repressor of cyclic adenosine 3′,5′- monophosphate (cAMP)-regulated enhancer-binding protein activity inhibits the cAMP-mediated induction of the somatostatin promoter in vivo
27. Inducible regulatory elements in the human cyclin D1 promoter
28. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei
29. Does antisense exist?