Structure-activity relationship of nonacidic quinazolinone inhibitors of human microsomal prostaglandin synthase 1 (mPGES 1)

Journal of Medicinal Chemistry

Volumn 55, Issue 8, 2012, Pages 3792-3803

  Rörsch, Florian ^a   Buscató, Estel La ^a   Deckmann, Klaus ^a   Schneider, Gisbert ^b   Schubert Zsilavecz, Manfred ^a   Geisslinger, Gerd ^a   Proschak, Ewgenij ^a   Grösch, Sabine ^a  

^a GOETHE UNIVERSITY   (Germany)

^b ETH ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

AF 3442; FR 20; ICOSANOID; MF 63; PF 9184; PROSTAGLANDIN SYNTHASE; PROSTAGLANDIN SYNTHASE INHIBITOR; QUINAZOLINONE DERIVATIVE; UNCLASSIFIED DRUG; YS 121;

ANIMAL CELL; ARTICLE; DRUG EFFECT; ENZYME INHIBITION; HELA CELL; HUMAN; HUMAN CELL; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MOUSE; NONHUMAN; STRUCTURE ACTIVITY RELATION;

ANIMALS; BIOLOGICAL AVAILABILITY; CELL LINE, TUMOR; CELL SURVIVAL; ENZYME INHIBITORS; HELA CELLS; HUMANS; INTRAMOLECULAR OXIDOREDUCTASES; MICE; MICROSOMES; QUINAZOLINONES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84860294771     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm201687d     Document Type: Article

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