-
1
-
-
0242321826
-
Microsomal prostaglandin e synthase-1 is the central switch during immune-induced pyresis
-
Engblom D, Saha S, Engstrom L, Westman M, Audoly LP, J akobsson PJ, Blomqvist A. Microsomal prostaglandin E synthase-1 is the central switch during immune-induced pyresis. Nat Neurosci. 2003 6 : 1137 8.
-
(2003)
Nat Neurosci.
, vol.6
, pp. 1137-8
-
-
Engblom, D.1
Saha, S.2
Engstrom, L.3
Westman, M.4
Audoly, L.P.5
Akobsson, P.J.J.6
Blomqvist, A.7
-
2
-
-
0035932121
-
Interleukin-1beta-mediated induction of Cox-2 in the CNS contributes to inflammatory pain hypersensitivity
-
Samad TA, Moore KA, Sapirstein A, Billet S, Allchorne A, Poole S, Bonventre JV, Woolf CJ. Interleukin-1beta-mediated induction of Cox-2 in the CNS contributes to inflammatory pain hypersensitivity. Nature. 2001 410 : 471 5.
-
(2001)
Nature.
, vol.410
, pp. 471-5
-
-
Samad, T.A.1
Moore, K.A.2
Sapirstein, A.3
Billet, S.4
Allchorne, A.5
Poole, S.6
Bonventre, J.V.7
Woolf, C.J.8
-
3
-
-
0043261465
-
Impaired inflammatory and pain responses in mice lacking an inducible prostaglandin e synthase
-
Trebino CE, Stock JL, Gibbons CP, Naiman BM, Wachtmann TS, Umland JP, Pandher K, Lapointe JM, Saha S, Roach ML, Carter D, Thomas NA, Durtschi BA, McNeish JD, Hambor JE, Jakobsson PJ, Carty TJ, Perez JR, Audoly LP. Impaired inflammatory and pain responses in mice lacking an inducible prostaglandin E synthase. Proc Natl Acad Sci USA. 2003 100 : 9044 9.
-
(2003)
Proc Natl Acad Sci USA.
, vol.100
, pp. 9044-9
-
-
Trebino, C.E.1
Stock, J.L.2
Gibbons, C.P.3
Naiman, B.M.4
Wachtmann, T.S.5
Umland, J.P.6
Pandher, K.7
Lapointe, J.M.8
Saha, S.9
Roach, M.L.10
Carter, D.11
Thomas, N.A.12
Durtschi, B.A.13
McNeish, J.D.14
Hambor, J.E.15
Jakobsson, P.J.16
Carty, T.J.17
Perez, J.R.18
Audoly, L.P.19
-
5
-
-
4043169152
-
Reduced pain hypersensitivity and inflammation in mice lacking microsomal prostaglandin e synthase-1
-
Kamei D, Yamakawa K, Takegoshi Y, Mikami-Nakanishi M, Nakatani Y, Oh-Ishi S, Yasui H, Azuma Y, Hirasawa N, Ohuchi K, Kawaguchi H, Ishikawa Y, Ishii T, Uematsu S, Akira S, Murakami M, Kudo I. Reduced pain hypersensitivity and inflammation in mice lacking microsomal prostaglandin e synthase-1. J Biol Chem. 2004 279 : 33684 95.
-
(2004)
J Biol Chem.
, vol.279
, pp. 33684-95
-
-
Kamei, D.1
Yamakawa, K.2
Takegoshi, Y.3
Mikami-Nakanishi, M.4
Nakatani, Y.5
Oh-Ishi, S.6
Yasui, H.7
Azuma, Y.8
Hirasawa, N.9
Ohuchi, K.10
Kawaguchi, H.11
Ishikawa, Y.12
Ishii, T.13
Uematsu, S.14
Akira, S.15
Murakami, M.16
Kudo, I.17
-
6
-
-
33746068237
-
Is mPGES-1 a promising target for pain therapy?
-
Scholich K, Geisslinger G. Is mPGES-1 a promising target for pain therapy? Trends Pharmacol Sci. 2006 27 : 399 401.
-
(2006)
Trends Pharmacol Sci.
, vol.27
, pp. 399-401
-
-
Scholich, K.1
Geisslinger, G.2
-
7
-
-
20444494334
-
Redirection of eicosanoid metabolism in mPGES-1-deficient macrophages
-
Trebino CE, Eskra JD, Wachtmann TS, Perez JR, Carty TJ, Audoly LP. Redirection of eicosanoid metabolism in mPGES-1-deficient macrophages. J Biol Chem. 2005 280 : 16579 85.
-
(2005)
J Biol Chem.
, vol.280
, pp. 16579-85
-
-
Trebino, C.E.1
Eskra, J.D.2
Wachtmann, T.S.3
Perez, J.R.4
Carty, T.J.5
Audoly, L.P.6
-
8
-
-
2542481948
-
Deletion of microsomal prostaglandin E2 (PGE2) synthase-1 reduces inducible and basal PGE2 production and alters the gastric prostanoid profile
-
Boulet L, Ouellet M, Bateman KP, Ethier D, Percival MD, Riendeau D, Mancini JA, Methot N. Deletion of microsomal prostaglandin E2 (PGE2) synthase-1 reduces inducible and basal PGE2 production and alters the gastric prostanoid profile. J Biol Chem. 2004 279 : 23229 37.
-
(2004)
J Biol Chem.
, vol.279
, pp. 23229-37
-
-
Boulet, L.1
Ouellet, M.2
Bateman, K.P.3
Ethier, D.4
Percival, M.D.5
Riendeau, D.6
Mancini, J.A.7
Methot, N.8
-
9
-
-
33646415952
-
Cyclooxygenases, microsomal prostaglandin e synthase-1, and Cardiovascular function
-
Cheng Y, Wang M, Yu Y, Lawson J, Funk CD, Fitzgerald GA. Cyclooxygenases, microsomal prostaglandin E synthase-1, and Cardiovascular function. J Clin Invest. 2006 116 : 1391 9.
-
(2006)
J Clin Invest.
, vol.116
, pp. 1391-9
-
-
Cheng, Y.1
Wang, M.2
Yu, Y.3
Lawson, J.4
Funk, C.D.5
Fitzgerald, G.A.6
-
10
-
-
0037195056
-
Prostacyclin-deficient mice develop ischemic renal disorders, including nephrosclerosis and renal infarction
-
Yokoyama C, Yabuki T, Shimonishi M, Wada M, Hatae T, Ohkawara S, Takeda J, Kinoshita T, Okabe M, Tanabe T. Prostacyclin-deficient mice develop ischemic renal disorders, including nephrosclerosis and renal infarction. Circulation. 2002 106 : 2397 403.
-
(2002)
Circulation.
, vol.106
, pp. 2397-403
-
-
Yokoyama, C.1
Yabuki, T.2
Shimonishi, M.3
Wada, M.4
Hatae, T.5
Ohkawara, S.6
Takeda, J.7
Kinoshita, T.8
Okabe, M.9
Tanabe, T.10
-
11
-
-
0037817373
-
Functional characterization of prostaglandin F2alpha receptor in the spinal cord for tactile pain (allodynia)
-
Muratani T, Nishizawa M, Matsumura S, Mabuchi T, Abe K, Shimamoto K, Minami T, Ito S. Functional characterization of prostaglandin F2alpha receptor in the spinal cord for tactile pain (allodynia). J Neurochem. 2003 86 : 374 82.
-
(2003)
J Neurochem.
, vol.86
, pp. 374-82
-
-
Muratani, T.1
Nishizawa, M.2
Matsumura, S.3
Mabuchi, T.4
Abe, K.5
Shimamoto, K.6
Minami, T.7
Ito, S.8
-
12
-
-
0030816051
-
Altered pain perception and inflammatory response in mice lacking prostacyclin receptor
-
Murata T, Ushikubi F, Matsuoka T, Hirata M, Yamasaki A, Sugimoto Y, Ichikawa A, Aze Y, Tanaka T, Yoshida N, Ueno A, Oh-ishi S, Narumiya S. Altered pain perception and inflammatory response in mice lacking prostacyclin receptor. Nature. 1997 388 : 678 82.
-
(1997)
Nature.
, vol.388
, pp. 678-82
-
-
Murata, T.1
Ushikubi, F.2
Matsuoka, T.3
Hirata, M.4
Yamasaki, A.5
Sugimoto, Y.6
Ichikawa, A.7
Aze, Y.8
Tanaka, T.9
Yoshida, N.10
Ueno, A.11
Oh-Ishi, S.12
Narumiya, S.13
-
13
-
-
0036276229
-
Spinal administration of prostaglandin E(2) or prostaglandin F(2alpha) primarily produces mechanical hyperalge-sia that is mediated by nociceptive specific spinal dorsal horn neurons
-
Turnbach ME, Spraggins DS, Randich A. Spinal administration of prostaglandin E(2) or prostaglandin F(2alpha) primarily produces mechanical hyperalge-sia that is mediated by nociceptive specific spinal dorsal horn neurons. Pain. 2002 97 : 33 45.
-
(2002)
Pain.
, vol.97
, pp. 33-45
-
-
Turnbach, M.E.1
Spraggins, D.S.2
Randich, A.3
-
14
-
-
13044249874
-
Lack of tactile pain (allodynia) in lipocalin-type prostaglandin D synthase-deficient mice
-
Eguchi N, Minami T, Shirafuji N, Kanaoka Y, Tanaka T, Nagata A, Yoshida N, Urade Y, Ito S, Hayaishi O. Lack of tactile pain (allodynia) in lipocalin-type prostaglandin D synthase-deficient mice. Proc Natl Acad Sci USA. 1999 96 : 726 30.
-
(1999)
Proc Natl Acad Sci USA.
, vol.96
, pp. 726-30
-
-
Eguchi, N.1
Minami, T.2
Shirafuji, N.3
Kanaoka, Y.4
Tanaka, T.5
Nagata, A.6
Yoshida, N.7
Urade, Y.8
Ito, S.9
Hayaishi, O.10
-
15
-
-
42349107333
-
Evaluation of inflammation and pain responses in mPGES-1 deficient mice
-
DeVito J, Devlin E, Schroeder K, Engle S, Swinton P, Sinha K, Bruno J, Souness J, Guehring H. Evaluation of inflammation and pain responses in mPGES-1 deficient mice. Inflamm Res. 2004 53 : 228.
-
(2004)
Inflamm Res.
, vol.53
, pp. 228
-
-
Devito, J.1
Devlin, E.2
Schroeder, K.3
Engle, S.4
Swinton, P.5
Sinha, K.6
Bruno, J.7
Souness, J.8
Guehring, H.9
-
16
-
-
33746578684
-
Inhibition of prostaglandin E2 synthesis by SC-560 is independent of cyclooxygenase 1 inhibition
-
Brenneis C, Maier TJ, Schmidt R, Hofacker A, Zulauf L, Jakobsson PJ, Scholich K, Geisslinger G. Inhibition of prostaglandin E2 synthesis by SC-560 is independent of cyclooxygenase 1 inhibition. FASEB J. 2006 20 : 1352 60.
-
(2006)
FASEB J.
, vol.20
, pp. 1352-60
-
-
Brenneis, C.1
Maier, T.J.2
Schmidt, R.3
Hofacker, A.4
Zulauf, L.5
Jakobsson, P.J.6
Scholich, K.7
Geisslinger, G.8
-
17
-
-
25644444564
-
Downregulation of cytosolic prostaglandin E2 synthase results in decreased nociceptive behavior in rats
-
Hofacker A, Coste O, Nguyen HV, Marian C, Scholich K, Geisslinger G. Downregulation of cytosolic prostaglandin E2 synthase results in decreased nociceptive behavior in rats. J Neurosci. 2005 25 : 9005 9.
-
(2005)
J Neurosci.
, vol.25
, pp. 9005-9
-
-
Hofacker, A.1
Coste, O.2
Nguyen, H.V.3
Marian, C.4
Scholich, K.5
Geisslinger, G.6
-
18
-
-
1042278007
-
Protein associated with Myc (PAM) is involved in spinal noci-ceptive processing
-
Ehnert C, Tegeder I, Pierre S, Birod K, Nguyen HV, Schmidtko A, Geisslinger G, Scholich K. Protein associated with Myc (PAM) is involved in spinal noci-ceptive processing. J Neurochem. 2004 88 : 948 57.
-
(2004)
J Neurochem.
, vol.88
, pp. 948-57
-
-
Ehnert, C.1
Tegeder, I.2
Pierre, S.3
Birod, K.4
Nguyen, H.V.5
Schmidtko, A.6
Geisslinger, G.7
Scholich, K.8
-
19
-
-
33749867157
-
Analyzing pro-teome topology and function by automated multidimensional fluorescence microscopy
-
Schubert W, Bonnekoh B, Pommer AJ, Philipsen L, Bockelmann R, Malykh Y, Gollnick H, Friedenberger M, Bode M, Dress AW. Analyzing pro-teome topology and function by automated multidimensional fluorescence microscopy. Nat Biotechnol. 2006 24 : 1270 8.
-
(2006)
Nat Biotechnol.
, vol.24
, pp. 1270-8
-
-
Schubert, W.1
Bonnekoh, B.2
Pommer, A.J.3
Philipsen, L.4
Bockelmann, R.5
Malykh, Y.6
Gollnick, H.7
Friedenberger, M.8
Bode, M.9
Dress, A.W.10
-
20
-
-
0033028718
-
Characterization of the analgesic and anti-inflammatory activities of ketorolac and its enantiomers in the rat
-
Jett MF, Ramesha CS, Brown CD, Chiu S, Emmett C, Voronin T, Sun T, O'Yang C, Hunter JC, Eglen RM, Johnson RM. Characterization of the analgesic and anti-inflammatory activities of ketorolac and its enantiomers in the rat. J Pharmacol Exp Ther. 1999 288 : 1288 97.
-
(1999)
J Pharmacol Exp Ther.
, vol.288
, pp. 1288-97
-
-
Jett, M.F.1
Ramesha, C.S.2
Brown, C.D.3
Chiu, S.4
Emmett, C.5
Voronin, T.6
Sun, T.7
O'Yang, C.8
Hunter, J.C.9
Eglen, R.M.10
Johnson, R.M.11
-
21
-
-
0037148136
-
Central nociceptive role of prostacyclin (IP) receptor induced by peripheral inflammation
-
Doi Y, Minami T, Nishizawa M, Mabuchi T, Mori H, Ito S. Central nociceptive role of prostacyclin (IP) receptor induced by peripheral inflammation. Neuroreport. 2002 13 : 93 6.
-
(2002)
Neuroreport.
, vol.13
, pp. 93-6
-
-
Doi, Y.1
Minami, T.2
Nishizawa, M.3
Mabuchi, T.4
Mori, H.5
Ito, S.6
-
22
-
-
0036172409
-
The spinal phospholi-pase-cyclooxygenase-prostanoid cascade in noci-ceptive processing
-
Svensson CI, Yaksh TL. The spinal phospholi-pase-cyclooxygenase- prostanoid cascade in noci-ceptive processing. Annu Rev Pharmacol Toxicol. 2002 42 : 553 83.
-
(2002)
Annu Rev Pharmacol Toxicol.
, vol.42
, pp. 553-83
-
-
Svensson, C.I.1
Yaksh, T.L.2
-
23
-
-
0035081365
-
Prostaglandins and cyclooxygenases in the spinal cord
-
Vanegas H, Schaible HG. Prostaglandins and cyclooxygenases in the spinal cord. Prog Neurobiol. 2001 64 : 327 63.
-
(2001)
Prog Neurobiol.
, vol.64
, pp. 327-63
-
-
Vanegas, H.1
Schaible, H.G.2
-
24
-
-
32244442817
-
RO1138452 and RO3244794: Characterization of structurally distinct, potent and selective IP (prostacyclin) receptor antagonists
-
Bley KR, Bhattacharya A, Daniels DV, Gever J, Jahangir A, O'Yang C, Smith S, Srinivasan D, Ford AP, Jett MF. RO1138452 and RO3244794: characterization of structurally distinct, potent and selective IP (prostacyclin) receptor antagonists. Br J Pharmacol. 2006 147 : 335 45.
-
(2006)
Br J Pharmacol.
, vol.147
, pp. 335-45
-
-
Bley, K.R.1
Bhattacharya, A.2
Daniels, D.V.3
Gever, J.4
Jahangir, A.5
O'Yang, C.6
Smith, S.7
Srinivasan, D.8
Ford, A.P.9
Jett, M.F.10
-
26
-
-
33751175676
-
Prostacyclin antagonism reduces pain and inflammation in rodent models of hyperalgesia and chronic arthritis
-
Pulichino AM, Rowland S, Wu T, Clark P, Xu D, Mathieu MC, Riendeau D, Audoly LP. Prostacyclin antagonism reduces pain and inflammation in rodent models of hyperalgesia and chronic arthritis. J Pharmacol Exp Ther. 2006 319 : 1043 50.
-
(2006)
J Pharmacol Exp Ther.
, vol.319
, pp. 1043-50
-
-
Pulichino, A.M.1
Rowland, S.2
Wu, T.3
Clark, P.4
Xu, D.5
Mathieu, M.C.6
Riendeau, D.7
Audoly, L.P.8
-
27
-
-
33845618517
-
Shunting of prostanoid biosynthesis in microsomal prostaglandin e synthase-1 null embryo fibroblasts: Regulatory effects on inducible nitric oxide synthase expression and nitrite synthesis
-
Kapoor M, Kojima F, Qian M, Yang L, Crofford LJ. Shunting of prostanoid biosynthesis in microsomal prostaglandin E synthase-1 null embryo fibroblasts: regulatory effects on inducible nitric oxide synthase expression and nitrite synthesis. FASEB J. 2006 20 : 2387 9.
-
(2006)
FASEB J.
, vol.20
, pp. 2387-9
-
-
Kapoor, M.1
Kojima, F.2
Qian, M.3
Yang, L.4
Crofford, L.J.5
-
28
-
-
4444262310
-
Pharmacology and signaling of prostaglandin receptors: Multiple roles in inflammation and immune modulation
-
Hata AN, Breyer RM. Pharmacology and signaling of prostaglandin receptors: multiple roles in inflammation and immune modulation. Pharmacol Ther. 2004 103 : 147 66.
-
(2004)
Pharmacol Ther.
, vol.103
, pp. 147-66
-
-
Hata, A.N.1
Breyer, R.M.2
-
29
-
-
33749263692
-
Deletion of microsomal prostaglandin e synthase-1 augments prostacyclin and retards atherogenesis
-
Wang M, Zukas AM, Hui Y, Ricciotti E, Pure E, FitzGerald GA. Deletion of microsomal prostaglandin E synthase-1 augments prostacyclin and retards atherogenesis. Proc Natl Acad Sci USA. 2006 103 : 14507 12.
-
(2006)
Proc Natl Acad Sci USA.
, vol.103
, pp. 14507-12
-
-
Wang, M.1
Zukas, A.M.2
Hui, Y.3
Ricciotti, E.4
Pure, E.5
Fitzgerald, G.A.6
|