-
1
-
-
33748475550
-
Andrews' diseases of the skin: Clinical dermatology
-
11th ed. Philadelphia, PA: Saunders Elsevier
-
James W, Berger T, Elston D., Andrews' diseases of the skin: clinical dermatology, 11th ed. Epidermal nevi, neoplasms, and cysts. Philadelphia, PA: Saunders Elsevier, 2011; 663.
-
(2011)
Epidermal Nevi, Neoplasms, and Cysts.
, pp. 663
-
-
James, W.1
Berger, T.2
Elston, D.3
-
2
-
-
0022649866
-
The Cowden syndrome: A clinical and genetic study in 21 patients
-
Starink TM, van der Veen JP, Arwert F, et al., The Cowden syndrome: a clinical and genetic study in 21 patients. Clin Genet 1986; 29: 222.
-
(1986)
Clin Genet
, vol.29
, pp. 222
-
-
Starink, T.M.1
Van Der Veen, J.P.2
Arwert, F.3
-
3
-
-
58849157647
-
Cowden syndrome: A critical review of the clinical literature
-
Pilarski R., Cowden syndrome: a critical review of the clinical literature. J Genet Couns 2009; 18: 13.
-
(2009)
J Genet Couns
, vol.18
, pp. 13
-
-
Pilarski, R.1
-
4
-
-
0020584790
-
Cowden's disease (multiple hamartoma and neoplasia syndrome). A case report and review of the English literature
-
Salem OS, Steck WD., Cowden's disease (multiple hamartoma and neoplasia syndrome). A case report and review of the English literature. J Am Acad Dermatol 1983; 8: 686.
-
(1983)
J Am Acad Dermatol
, vol.8
, pp. 686
-
-
Salem, O.S.1
Steck, W.D.2
-
5
-
-
6844252284
-
Mutation spectrum and genotype-phenotype analyses in Cowden disease and Bannayan-Zonana syndrome, two hamartoma syndromes with germline PTEN mutation
-
Marsh DJ, Coulon V, Lunetta KL, et al., Mutation spectrum and genotype-phenotype analyses in Cowden disease and Bannayan-Zonana syndrome, two hamartoma syndromes with germline PTEN mutation. Hum Mol Genet 1998; 7: 507.
-
(1998)
Hum Mol Genet
, vol.7
, pp. 507
-
-
Marsh, D.J.1
Coulon, V.2
Lunetta, K.L.3
-
7
-
-
0032905101
-
Novel PTEN mutations in patients with Cowden disease: Absence of clear genotype-phenotype correlations
-
Nelen MR, Kremer H, Konings IB, et al., Novel PTEN mutations in patients with Cowden disease: absence of clear genotype-phenotype correlations. Eur J Hum Genet 1999; 7: 267.
-
(1999)
Eur J Hum Genet
, vol.7
, pp. 267
-
-
Nelen, M.R.1
Kremer, H.2
Konings, I.B.3
-
8
-
-
0042316755
-
PTEN: One gene, many syndromes
-
Eng C., PTEN: one gene, many syndromes. Hum Mutat 2003; 22: 183.
-
(2003)
Hum Mutat
, vol.22
, pp. 183
-
-
Eng, C.1
-
9
-
-
0033738748
-
Will the real Cowden syndrome please stand up: Revised diagnostic criteria
-
Eng C., Will the real Cowden syndrome please stand up: revised diagnostic criteria. J Med Genet 2000; 37: 828.
-
(2000)
J Med Genet
, vol.37
, pp. 828
-
-
Eng, C.1
-
10
-
-
0032857217
-
Immunohistochemical evidence of loss of PTEN expression in primary ductal adenocarcinomas of the breast
-
Perren A, Weng LP, Boag AH, et al., Immunohistochemical evidence of loss of PTEN expression in primary ductal adenocarcinomas of the breast. Am J Pathol 1999; 155: 1253.
-
(1999)
Am J Pathol
, vol.155
, pp. 1253
-
-
Perren, A.1
Weng, L.P.2
Boag, A.H.3
-
11
-
-
21044444976
-
Immunohistochemical analysis of PTEN in endometrial carcinoma: A tissue microarray study with a comparison of four commercial antibodies in correlation with molecular abnormalities
-
Pallares J, Bussaglia E, Martínez-Guitarte JL, et al., Immunohistochemical analysis of PTEN in endometrial carcinoma: a tissue microarray study with a comparison of four commercial antibodies in correlation with molecular abnormalities. Mod Pathol 2005; 18: 719.
-
(2005)
Mod Pathol
, vol.18
, pp. 719
-
-
Pallares, J.1
Bussaglia, E.2
Martínez-Guitarte, J.L.3
-
12
-
-
0031001041
-
TEP1, encoded by a candidate tumor suppressor locus, is a novel protein tyrosine phosphatase regulated by transforming growth factor beta
-
Li DM, Sun H., TEP1, encoded by a candidate tumor suppressor locus, is a novel protein tyrosine phosphatase regulated by transforming growth factor beta. Cancer Res 1997; 57: 2124.
-
(1997)
Cancer Res
, vol.57
, pp. 2124
-
-
Li, D.M.1
Sun, H.2
-
13
-
-
0032506011
-
The lipid phosphatase activity of PTEN is critical for its tumor suppressor function
-
Myers MP, Pass I, Batty IH, et al., The lipid phosphatase activity of PTEN is critical for its tumor suppressor function. Proc Natl Acad Sci U S A 1998; 95: 13513.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 13513
-
-
Myers, M.P.1
Pass, I.2
Batty, I.H.3
-
14
-
-
0032431032
-
The PTEN/MMAC1 tumor suppressor phosphatase functions as a negative regulator of the phosphoinositide 3-kinase/Akt pathway
-
Wu X, Senechal K, Neshat MS, Whang YE, Sawyers CL., The PTEN/MMAC1 tumor suppressor phosphatase functions as a negative regulator of the phosphoinositide 3-kinase/Akt pathway. Proc Natl Acad Sci U S A 1998; 95: 15587.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 15587
-
-
Wu, X.1
Senechal, K.2
Neshat, M.S.3
Whang, Y.E.4
Sawyers, C.L.5
-
15
-
-
3643119742
-
The phosphoinositol phosphatase activity of PTEN mediates a serum-sensitive G1 growth arrest in glioma cells
-
Furnari FB, Huang HJ, Cavenee WK., The phosphoinositol phosphatase activity of PTEN mediates a serum-sensitive G1 growth arrest in glioma cells. Cancer Res 1998; 58: 5002.
-
(1998)
Cancer Res
, vol.58
, pp. 5002
-
-
Furnari, F.B.1
Huang, H.J.2
Cavenee, W.K.3
-
16
-
-
0032431028
-
PTEN/MMAC1/TEP1 suppresses the tumorigenicity and induces G1 cell cycle arrest in human glioblastoma cells
-
Li DM, Sun H., PTEN/MMAC1/TEP1 suppresses the tumorigenicity and induces G1 cell cycle arrest in human glioblastoma cells. Proc Natl Acad Sci U S A 1998; 95: 15406.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 15406
-
-
Li, D.M.1
Sun, H.2
-
17
-
-
0033514509
-
Regulation of G1 progression by the PTEN tumor suppressor protein is linked to inhibition of the phosphatidylinositol 3-kinase/Akt pathway
-
Ramaswamy S, Nakamura N, Vazquez F, et al., Regulation of G1 progression by the PTEN tumor suppressor protein is linked to inhibition of the phosphatidylinositol 3-kinase/Akt pathway. Proc Natl Acad Sci U S A 1999; 96: 2110.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 2110
-
-
Ramaswamy, S.1
Nakamura, N.2
Vazquez, F.3
-
18
-
-
0032534963
-
The PTEN/MMAC1 tumor suppressor induces cell death that is rescued by the AKT/protein kinase B oncogene
-
Li J, Simpson L, Takahashi M, et al., The PTEN/MMAC1 tumor suppressor induces cell death that is rescued by the AKT/protein kinase B oncogene. Cancer Res 1998; 58: 5667.
-
(1998)
Cancer Res
, vol.58
, pp. 5667
-
-
Li, J.1
Simpson, L.2
Takahashi, M.3
-
19
-
-
0035869175
-
PTEN inhibits insulin-stimulated MEK/ MAPK activation and cell growth by blocking IRS-1 phosphorylation and IRS-1/Grb-2/Sos complex formation in a breast cancer model
-
Weng LP, Smith WM, Brown JL, Eng C., PTEN inhibits insulin-stimulated MEK/ MAPK activation and cell growth by blocking IRS-1 phosphorylation and IRS-1/Grb-2/Sos complex formation in a breast cancer model. Hum Mol Genet 2001; 10: 605.
-
(2001)
Hum Mol Genet
, vol.10
, pp. 605
-
-
Weng, L.P.1
Smith, W.M.2
Brown, J.L.3
Eng, C.4
-
20
-
-
0035869212
-
PTEN coordinates G(1) arrest by down-regulating cyclin D1 via its protein phosphatase activity and up-regulating p27 via its lipid phosphatase activity in a breast cancer model
-
Weng LP, Brown JL, Eng C., PTEN coordinates G(1) arrest by down-regulating cyclin D1 via its protein phosphatase activity and up-regulating p27 via its lipid phosphatase activity in a breast cancer model. Hum Mol Genet 2001; 10: 599.
-
(2001)
Hum Mol Genet
, vol.10
, pp. 599
-
-
Weng, L.P.1
Brown, J.L.2
Eng, C.3
-
21
-
-
0032486198
-
Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN
-
Tamura M, Gu J, Matsumoto K, Aota S, Parsons R, Yamada KM., Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN. Science 1998; 280: 1614.
-
(1998)
Science
, vol.280
, pp. 1614
-
-
Tamura, M.1
Gu, J.2
Matsumoto, K.3
Aota, S.4
Parsons, R.5
Yamada, K.M.6
-
22
-
-
0033606767
-
Shc and FAK differentially regulate cell motility and directionality modulated by PTEN
-
Gu J, Tamura M, Pankov R, et al., Shc and FAK differentially regulate cell motility and directionality modulated by PTEN. J Cell Biol 1999; 146: 389.
-
(1999)
J Cell Biol
, vol.146
, pp. 389
-
-
Gu, J.1
Tamura, M.2
Pankov, R.3
-
23
-
-
0030140025
-
Localization of the gene for Cowden disease to chromosome 10q22-23
-
Nelen MR, Padberg GW, Peeters EA, et al., Localization of the gene for Cowden disease to chromosome 10q22-23. Nat Genet 1996; 13: 114.
-
(1996)
Nat Genet
, vol.13
, pp. 114
-
-
Nelen, M.R.1
Padberg, G.W.2
Peeters, E.A.3
-
24
-
-
8544247944
-
Germline mutations in the PTEN/ MMAC1 gene in patients with Cowden disease
-
Nelen MR, van Staveren WC, Peeters EA, et al., Germline mutations in the PTEN/ MMAC1 gene in patients with Cowden disease. Hum Mol Genet 1997; 6: 1383.
-
(1997)
Hum Mol Genet
, vol.6
, pp. 1383
-
-
Nelen, M.R.1
Van Staveren, W.C.2
Peeters, E.A.3
-
25
-
-
0031004088
-
Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome
-
Liaw D, Marsh DJ, Li J, et al., Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome. Nat Genet 1997; 16: 64.
-
(1997)
Nat Genet
, vol.16
, pp. 64
-
-
Liaw, D.1
Marsh, D.J.2
Li, J.3
-
26
-
-
0032853452
-
PTEN mutation spectrum and genotype-phenotype correlations in Bannayan-Riley-Ruvalcaba syndrome suggest a single entity with Cowden syndrome
-
Marsh DJ, Kum JB, Lunetta KL, et al., PTEN mutation spectrum and genotype-phenotype correlations in Bannayan-Riley-Ruvalcaba syndrome suggest a single entity with Cowden syndrome. Hum Mol Genet 1999; 8: 1472.
-
(1999)
Hum Mol Genet
, vol.8
, pp. 1472
-
-
Marsh, D.J.1
Kum, J.B.2
Lunetta, K.L.3
-
27
-
-
0035928416
-
Association of germline mutation in the PTEN tumour suppressor gene and Proteus and Proteus-like syndromes
-
Zhou X, Hampel H, Thiele H, et al., Association of germline mutation in the PTEN tumour suppressor gene and Proteus and Proteus-like syndromes. Lancet 2001; 358: 210.
-
(2001)
Lancet
, vol.358
, pp. 210
-
-
Zhou, X.1
Hampel, H.2
Thiele, H.3
-
28
-
-
0242522403
-
Germline inactivation of PTEN and dysregulation of the phosphoinositol-3-kinase/Akt pathway cause human Lhermitte-Duclos disease in adults
-
Zhou XP, Marsh DJ, Morrison CD, et al., Germline inactivation of PTEN and dysregulation of the phosphoinositol-3-kinase/Akt pathway cause human Lhermitte-Duclos disease in adults. Am J Hum Genet 2003; 73: 1191.
-
(2003)
Am J Hum Genet
, vol.73
, pp. 1191
-
-
Zhou, X.P.1
Marsh, D.J.2
Morrison, C.D.3
-
29
-
-
20244367771
-
Subset of individuals with autism spectrum disorders and extreme macrocephaly associated with germline PTEN tumour suppressor gene mutations
-
Butler MG, Dasouki MJ, Zhou XP, et al., Subset of individuals with autism spectrum disorders and extreme macrocephaly associated with germline PTEN tumour suppressor gene mutations. J Med Genet 2005; 42: 318.
-
(2005)
J Med Genet
, vol.42
, pp. 318
-
-
Butler, M.G.1
Dasouki, M.J.2
Zhou, X.P.3
-
30
-
-
33847342035
-
Increasing knowledge of PTEN germline mutations: Two additional patients with autism and macrocephaly
-
Herman GE, Butter E, Enrile B, Pastore M, Prior TW, Sommer A., Increasing knowledge of PTEN germline mutations: two additional patients with autism and macrocephaly. Am J Med Genet A 2007; 143: 589.
-
(2007)
Am J Med Genet A
, vol.143
, pp. 589
-
-
Herman, G.E.1
Butter, E.2
Enrile, B.3
Pastore, M.4
Prior, T.W.5
Sommer, A.6
-
31
-
-
0032566064
-
Somatic deletion mapping on chromosome 10 and sequence analysis of PTEN/MMAC1 point to the 10q25-26 region as the primary target in low-grade and high-grade gliomas
-
Maier D, Zhang Z, Taylor E, et al., Somatic deletion mapping on chromosome 10 and sequence analysis of PTEN/MMAC1 point to the 10q25-26 region as the primary target in low-grade and high-grade gliomas. Oncogene 1998; 16: 3331.
-
(1998)
Oncogene
, vol.16
, pp. 3331
-
-
Maier, D.1
Zhang, Z.2
Taylor, E.3
-
32
-
-
0030799909
-
Somatic mutations of PTEN in glioblastoma multiforme
-
Wang SI, Puc J, Li J, et al., Somatic mutations of PTEN in glioblastoma multiforme. Cancer Res 1997; 57: 4183.
-
(1997)
Cancer Res
, vol.57
, pp. 4183
-
-
Wang, S.I.1
Puc, J.2
Li, J.3
-
33
-
-
0030761409
-
Mutations in PTEN are frequent in endometrial carcinoma but rare in other common gynecological malignancies
-
Tashiro H, Blazes MS, Wu R, et al., Mutations in PTEN are frequent in endometrial carcinoma but rare in other common gynecological malignancies. Cancer Res 1997; 57: 3935.
-
(1997)
Cancer Res
, vol.57
, pp. 3935
-
-
Tashiro, H.1
Blazes, M.S.2
Wu, R.3
-
34
-
-
0032482369
-
PTEN/ MMAC1/TEP1 involvement in primary prostate cancers
-
Pesche S, Latil A, Muzeau F, et al., PTEN/ MMAC1/TEP1 involvement in primary prostate cancers. Oncogene 1998; 16: 2879.
-
(1998)
Oncogene
, vol.16
, pp. 2879
-
-
Pesche, S.1
Latil, A.2
Muzeau, F.3
-
35
-
-
0033852872
-
Mutations of the human PTEN gene
-
Bonneau D, Longy M., Mutations of the human PTEN gene. Hum Mutat 2000; 16: 109.
-
(2000)
Hum Mutat
, vol.16
, pp. 109
-
-
Bonneau, D.1
Longy, M.2
-
36
-
-
0035029670
-
Somatic mutation and germline variants of MINPP1, a phosphatase gene located in proximity to PTEN on 10q23.3, in follicular thyroid carcinomas
-
Gimm O, Chi H, Dahia PL, et al., Somatic mutation and germline variants of MINPP1, a phosphatase gene located in proximity to PTEN on 10q23.3, in follicular thyroid carcinomas. J Clin Endocrinol Metab 2001; 86: 1801.
-
(2001)
J Clin Endocrinol Metab
, vol.86
, pp. 1801
-
-
Gimm, O.1
Chi, H.2
Dahia, P.L.3
-
37
-
-
0033843623
-
Differential nuclear and cytoplasmic expression of PTEN in normal thyroid tissue, and benign and malignant epithelial thyroid tumors
-
Gimm O, Perren A, Weng LP, et al., Differential nuclear and cytoplasmic expression of PTEN in normal thyroid tissue, and benign and malignant epithelial thyroid tumors. Am J Pathol 2000; 156: 1693.
-
(2000)
Am J Pathol
, vol.156
, pp. 1693
-
-
Gimm, O.1
Perren, A.2
Weng, L.P.3
-
38
-
-
0031661833
-
Somatic mutations of the PTEN tumor suppressor gene in sporadic follicular thyroid tumors
-
Halachmi N, Halachmi S, Evron E, et al., Somatic mutations of the PTEN tumor suppressor gene in sporadic follicular thyroid tumors. Genes Chromosomes Cancer 1998; 23: 239.
-
(1998)
Genes Chromosomes Cancer
, vol.23
, pp. 239
-
-
Halachmi, N.1
Halachmi, S.2
Evron, E.3
-
39
-
-
0012746941
-
Allelic losses on chromosome arm 10q and mutation of the PTEN (MMAC1) tumour suppressor gene in primary and metastatic malignant melanomas
-
Reifenberger J, Wolter M, Boström J, et al., Allelic losses on chromosome arm 10q and mutation of the PTEN (MMAC1) tumour suppressor gene in primary and metastatic malignant melanomas. Virchows Arch 2000; 436: 487.
-
(2000)
Virchows Arch
, vol.436
, pp. 487
-
-
Reifenberger, J.1
Wolter, M.2
Boström, J.3
-
40
-
-
33644774541
-
Examination of mutations in BRAF, NRAS and PTEN in primary cutaneous melanoma
-
Goel V, Lazar AJ, Redston M, Haluska FG., Examination of mutations in BRAF, NRAS and PTEN in primary cutaneous melanoma. J Invest Dermatol 2006; 126: 154.
-
(2006)
J Invest Dermatol
, vol.126
, pp. 154
-
-
Goel, V.1
Lazar, A.J.2
Redston, M.3
Haluska, F.G.4
-
41
-
-
0032938598
-
Lack of somatic mutation in the PTEN gene in squamous cell carcinomas of human skin
-
Kubo Y, Urano Y, Hida Y, Arase S., Lack of somatic mutation in the PTEN gene in squamous cell carcinomas of human skin. J Dermatol Sci 1999; 19: 199.
-
(1999)
J Dermatol Sci
, vol.19
, pp. 199
-
-
Kubo, Y.1
Urano, Y.2
Hida, Y.3
Arase, S.4
-
42
-
-
0035342578
-
Frequent allelic loss at 10q23 but low incidence of PTEN mutations in Merkel cell carcinoma
-
Van Gele M, Leonard JH, Van Roy N, Cook AL, De Paepe A, Speleman F., Frequent allelic loss at 10q23 but low incidence of PTEN mutations in Merkel cell carcinoma. Int J Cancer 2001; 92: 409.
-
(2001)
Int J Cancer
, vol.92
, pp. 409
-
-
Van Gele, M.1
Leonard, J.H.2
Van Roy, N.3
Cook, A.L.4
De Paepe, A.5
Speleman, F.6
-
43
-
-
0032474749
-
Identification of PTEN/MMAC1 alterations in uncultured melanomas and melanoma cell lines
-
Tsao H, Zhang X, Benoit E, Haluska FG., Identification of PTEN/MMAC1 alterations in uncultured melanomas and melanoma cell lines. Oncogene 1998; 16: 3397.
-
(1998)
Oncogene
, vol.16
, pp. 3397
-
-
Tsao, H.1
Zhang, X.2
Benoit, E.3
Haluska, F.G.4
-
44
-
-
0030777104
-
Disruption of the MMAC1/PTEN gene by deletion or mutation is a frequent event in malignant melanoma
-
Guldberg P, thor Straten P, Birck A, Ahrenkiel V, Kirkin AF, Zeuthen J., Disruption of the MMAC1/PTEN gene by deletion or mutation is a frequent event in malignant melanoma. Cancer Res 1997; 57: 3660.
-
(1997)
Cancer Res
, vol.57
, pp. 3660
-
-
Guldberg, P.1
Thor Straten, P.2
Birck, A.3
Ahrenkiel, V.4
Kirkin, A.F.5
Zeuthen, J.6
-
45
-
-
2342504508
-
Frequent inactivation of PTEN by promoter hypermethylation in microsatellite instability-high sporadic colorectal cancers
-
Goel A, Arnold CN, Niedzwiecki D, et al., Frequent inactivation of PTEN by promoter hypermethylation in microsatellite instability-high sporadic colorectal cancers. Cancer Res 2004; 64: 3014.
-
(2004)
Cancer Res
, vol.64
, pp. 3014
-
-
Goel, A.1
Arnold, C.N.2
Niedzwiecki, D.3
-
46
-
-
77249150002
-
Synchronous bilateral breast carcinoma in a patient with Cowden syndrome: A case report with morphologic, immunohistochemical and genetic analysis
-
Peirõ G, Adrover E, Guijarro J, et al., Synchronous bilateral breast carcinoma in a patient with Cowden syndrome: a case report with morphologic, immunohistochemical and genetic analysis. Breast J 2010; 16: 77.
-
(2010)
Breast J
, vol.16
, pp. 77
-
-
Peirõ, G.1
Adrover, E.2
Guijarro, J.3
-
47
-
-
33646065648
-
Cowden syndrome: Report of a case with immunohistochemical analysis and review of the literature
-
Scheper MA, Nikitakis NG, Sarlani E, Sauk JJ, Meiller TF., Cowden syndrome: report of a case with immunohistochemical analysis and review of the literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2006; 101: 625.
-
(2006)
Oral Surg Oral Med Oral Pathol Oral Radiol Endod
, vol.101
, pp. 625
-
-
Scheper, M.A.1
Nikitakis, N.G.2
Sarlani, E.3
Sauk, J.J.4
Meiller, T.F.5
-
48
-
-
80053375204
-
Immunohistochemical staining of thyroidectomy specimens for PTEN can aid in the identification of patients with Cowden syndrome
-
Barletta JA, Bellizzi AM, Hornick JL., Immunohistochemical staining of thyroidectomy specimens for PTEN can aid in the identification of patients with Cowden syndrome. Am J Surg Pathol 2011; 35: 1505.
-
(2011)
Am J Surg Pathol
, vol.35
, pp. 1505
-
-
Barletta, J.A.1
Bellizzi, A.M.2
Hornick, J.L.3
|