Allelic losses on chromosome arm 10q and mutation of the PTEN (MMAC1) tumour suppressor gene in primary and metastatic malignant melanomas

Virchows Archiv

Volumn 436, Issue 5, 2000, Pages 487-493

  Reifenberger, Julia ^a   Wolter, Marietta ^b   Boström, Jan ^b   Büschges, Rainer ^b   Schulte, Klaus W ^a   Megahed, Mosaad ^a   Ruzicka, Thomas ^a   Reifenberger, Guido ^b  

^a HEINRICH HEINE UNIVERSITY   (Germany)

^b UNIVERSITY HOSPITAL BONN   (Germany)

Author keywords

Chromosome 10; Loss of heterozygosity; Molecular genetics; PTEN; Skin tumours

Indexed keywords

MICROSATELLITE DNA;

ADULT; AGED; ARTICLE; CANCER GENETICS; CHROMOSOME 10Q; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GENE DELETION; GENE LOSS; GENE MUTATION; HETEROZYGOSITY LOSS; HUMAN; HUMAN CELL; MALE; MELANOMA; PRIORITY JOURNAL; SKIN TUMOR; TUMOR SUPPRESSOR GENE;

ADULT; AGED; AGED, 80 AND OVER; CHROMOSOMES, HUMAN, PAIR 10; DNA, NEOPLASM; FEMALE; GENES, TUMOR SUPPRESSOR; HUMANS; LOSS OF HETEROZYGOSITY; MALE; MELANOMA; MICROSATELLITE REPEATS; MIDDLE AGED; MUTATION; PHOSPHORIC MONOESTER HYDROLASES; PTEN PHOSPHOHYDROLASE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, NEOPLASM; SKIN NEOPLASMS; TUMOR SUPPRESSOR PROTEINS;

EID: 0012746941     PISSN: 09456317     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004280050477     Document Type: Article

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