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Volumn 94, Issue 2, 2012, Pages 304-315

Nitric oxide synthase in post-ischaemic remodelling: New pathways and mechanisms

Author keywords

Cardiac remodelling; Heart failure; Hypertrophy; Nitric oxide synthase; Protein kinase G

Indexed keywords

BETA 3 ADRENERGIC RECEPTOR; CINACIGUAT; CYCLIC GMP; ENDOTHELIAL NITRIC OXIDE SYNTHASE; FOLIC ACID; GUANYLATE CYCLASE ACTIVATOR; INDUCIBLE NITRIC OXIDE SYNTHASE; NEURONAL NITRIC OXIDE SYNTHASE; PHOSPHODIESTERASE 5A INHIBITOR; PHOSPHODIESTERASE V INHIBITOR; TETRAHYDROBIOPTERIN; UNCLASSIFIED DRUG;

EID: 84860137298     PISSN: 00086363     EISSN: 17553245     Source Type: Journal    
DOI: 10.1093/cvr/cvr360     Document Type: Review
Times cited : (19)

References (114)
  • 1
    • 64749090979 scopus 로고    scopus 로고
    • ENOS activation by physical forces: From short-term regulation of contraction to chronic remodeling of cardiovascular tissues
    • Balligand JL, Feron O, Dessy C. eNOS activation by physical forces: from short-term regulation of contraction to chronic remodeling of cardiovascular tissues. Physiol Rev 2009;89:481-534.
    • (2009) Physiol Rev , vol.89 , pp. 481-534
    • Balligand, J.L.1    Feron, O.2    Dessy, C.3
  • 2
    • 38849108758 scopus 로고    scopus 로고
    • Does nitric oxide modulate cardiac ryanodine receptor function? Implications for excitation-contraction coupling
    • DOI 10.1093/cvr/cvm012
    • Lim G, Venetucci L, Eisner DA, Casadei B. Does nitric oxide modulate cardiac ryanodine receptor function? Implications for excitation-contraction coupling. Cardiovasc Res 2008;77:256-264. (Pubitemid 351197636)
    • (2008) Cardiovascular Research , vol.77 , Issue.2 , pp. 256-264
    • Lim, G.1    Venetucci, L.2    Eisner, D.A.3    Casadei, B.4
  • 3
    • 60349109393 scopus 로고    scopus 로고
    • Characteristics and function of cardiac mitochondrial nitric oxide synthase
    • Dedkova EN, Blatter LA. Characteristics and function of cardiac mitochondrial nitric oxide synthase. J Physiol 2009;587:851-872.
    • (2009) J Physiol , vol.587 , pp. 851-872
    • Dedkova, E.N.1    Blatter, L.A.2
  • 4
    • 6444242933 scopus 로고    scopus 로고
    • Role of myocardial neuronal nitric oxide synthase-derived nitric oxide in β-adrenergic hyporesponsiveness after myocardial infarction-induced heart failure in rat
    • DOI 10.1161/01.CIR.0000145160.04084.AC
    • Bendall JK, Damy T, Ratajczak P, Loyer X, Monceau V, Marty I et al. Role of myocardial neuronal nitric oxide synthase-derived nitric oxide in b-adrenergic hyporesponsiveness after myocardial infarction-induced heart failure in rat. Circulation 2004;110: 2368-2375. (Pubitemid 39407341)
    • (2004) Circulation , vol.110 , Issue.16 , pp. 2368-2375
    • Bendall, J.K.1    Damy, T.2    Ratajczak, P.3    Loyer, X.4    Monceau, V.5    Marty, I.6    Milliez, P.7    Robidel, E.8    Marotte, F.9    Samuel, J.-L.10    Heymes, C.11
  • 6
    • 14644423890 scopus 로고    scopus 로고
    • NO/redox disequilibrium in the failing heart and cardiovascular system
    • DOI 10.1172/JCI200524459
    • Hare JM, Stamler JS. NO/redox disequilibrium in the failing heart and cardiovascular system. J Clin Invest 2005;115:509-517. (Pubitemid 40322220)
    • (2005) Journal of Clinical Investigation , vol.115 , Issue.3 , pp. 509-517
    • Hare, J.M.1    Stamler, J.S.2
  • 7
    • 34247468282 scopus 로고    scopus 로고
    • Relevance of nitric oxide for myocardial remodeling
    • Massion PB, Balligand JL. Relevance of nitric oxide for myocardial remodeling. Curr Heart Fail Rep 2007;4:18-25. (Pubitemid 46663315)
    • (2007) Current Heart Failure Reports , vol.4 , Issue.1 , pp. 18-25
    • Massion, P.B.1    Balligand, J.-L.2
  • 8
    • 84856008116 scopus 로고    scopus 로고
    • Nitric oxide synthase and cyclic GMP signaling in cardiac myocytes: From contractility to remodeling
    • Hammond J, Balligand JL. Nitric oxide synthase and cyclic GMP signaling in cardiac myocytes: from contractility to remodeling. J Mol Cell Cardiol 2012;52:330-340.
    • (2012) J Mol Cell Cardiol , vol.52 , pp. 330-340
    • Hammond, J.1    Balligand, J.L.2
  • 9
    • 79961062184 scopus 로고    scopus 로고
    • Towards a re-definition of 'cardiac hypertrophy' through a rational characterization of left ventricular phenotypes: A position paper of the Working Group 'Myocardial Function' of the ESC
    • Knoll R, Iaccarino G, Tarone G, Hilfiker-Kleiner D, Bauersachs J, Leite-Moreira AF et al. Towards a re-definition of 'cardiac hypertrophy' through a rational characterization of left ventricular phenotypes: a position paper of the Working Group 'Myocardial Function' of the ESC. Eur J Heart Fail 2011;13:811-819.
    • (2011) Eur J Heart Fail , vol.13 , pp. 811-819
    • Knoll, R.1    Iaccarino, G.2    Tarone, G.3    Hilfiker-Kleiner, D.4    Bauersachs, J.5    Leite-Moreira, A.F.6
  • 10
    • 0037173019 scopus 로고    scopus 로고
    • Cardiac nitric oxide synthase 1 regulates basal and β-adrenergic contractility in murine ventricular myocytes
    • DOI 10.1161/01.CIR.0000019516.31040.2D
    • Ashley EA, Sears CE, Bryant SM, Watkins HC, Casadei B. Cardiac nitric oxide synthase 1 regulates basal and b-adrenergic contractility in murine ventricular myocytes. Circulation 2002;105:3011-3016. (Pubitemid 34693835)
    • (2002) Circulation , vol.105 , Issue.25 , pp. 3011-3016
    • Ashley, E.A.1    Sears, C.E.2    Bryant, S.M.3    Watkins, H.C.4    Casadei, B.5
  • 11
    • 41149146649 scopus 로고    scopus 로고
    • Reduced phospholamban phosphorylation is associated with impaired relaxation in left ventricular myocytes from neuronal NO synthase-deficient mice
    • DOI 10.1161/CIRCRESAHA.107.164798
    • Zhang YH, Zhang MH, Sears CE, Emanuel K, Redwood C, El-Armouche A et al. Reduced phospholamban phosphorylation is associated with impaired relaxation in left ventricular myocytes from neuronal NO synthase-deficient mice. Circ Res 2008;102:242-249. (Pubitemid 351651129)
    • (2008) Circulation Research , vol.102 , Issue.2 , pp. 242-249
    • Zhang, Y.H.1    Zhang, M.H.2    Sears, C.E.3    Emanuel, K.4    Redwood, C.5    El-Armouche, A.6    Kranias, E.G.7    Casadei, B.8
  • 12
    • 77956525999 scopus 로고    scopus 로고
    • Regulation of myocyte contraction via neuronal nitric oxide synthase: Role of ryanodine receptor S-nitrosylation
    • Wang H, Viatchenko-Karpinski S, Sun J, Gyorke I, Benkusky NA, Kohr MJ et al. Regulation of myocyte contraction via neuronal nitric oxide synthase: role of ryanodine receptor S-nitrosylation. J Physiol 2010;588:2905-2917.
    • (2010) J Physiol , vol.588 , pp. 2905-2917
    • Wang, H.1    Viatchenko-Karpinski, S.2    Sun, J.3    Gyorke, I.4    Benkusky, N.A.5    Kohr, M.J.6
  • 13
    • 0037149489 scopus 로고    scopus 로고
    • Nitric oxide regulates the heart by spatial confinement of nitric oxide synthase isoforms
    • Barouch LA, Harrison RW, Skaf MW, Rosas GO, Cappola TP, Kobeissi ZA et al. Nitric oxide regulates the heart by spatial confinement of nitric oxide synthase isoforms. Nature 2002;416:337-339.
    • (2002) Nature , vol.416 , pp. 337-339
    • Barouch, L.A.1    Harrison, R.W.2    Skaf, M.W.3    Rosas, G.O.4    Cappola, T.P.5    Kobeissi, Z.A.6
  • 15
    • 33847048132 scopus 로고    scopus 로고
    • Conditional neuronal nitric oxide synthase overexpression impairs myocardial contractility
    • Burkard N, Rokita AG, Kaufmann SG, Hallhuber M, Wu R, Hu K et al. Conditional neuronal nitric oxide synthase overexpression impairs myocardial contractility. Circ Res 2007;100:e32-e44.
    • (2007) Circ Res , vol.100
    • Burkard, N.1    Rokita, A.G.2    Kaufmann, S.G.3    Hallhuber, M.4    Wu, R.5    Hu, K.6
  • 16
    • 51649088963 scopus 로고    scopus 로고
    • Cardiomyocyte overexpression of neuronal nitric oxide synthase delays transition toward heart failure in response to pressure overload by preserving calcium cycling
    • Loyer X, Gomez AM, Milliez P, Fernandez-Velasco M, Vangheluwe P, Vinet L et al. Cardiomyocyte overexpression of neuronal nitric oxide synthase delays transition toward heart failure in response to pressure overload by preserving calcium cycling. Circulation 2008;117:3187-3198.
    • (2008) Circulation , vol.117 , pp. 3187-3198
    • Loyer, X.1    Gomez, A.M.2    Milliez, P.3    Fernandez-Velasco, M.4    Vangheluwe, P.5    Vinet, L.6
  • 17
    • 66449090794 scopus 로고    scopus 로고
    • Specific role of neuronal nitric-oxide synthase when tethered to the plasma membrane calcium pump in regulating the b-adrenergic signal in the myocardium
    • Mohamed TM, Oceandy D, Prehar S, Alatwi N, Hegab Z, Baudoin FM et al. Specific role of neuronal nitric-oxide synthase when tethered to the plasma membrane calcium pump in regulating the b-adrenergic signal in the myocardium. J Biol Chem 2009;284:12091-12098.
    • (2009) J Biol Chem , vol.284 , pp. 12091-12098
    • Mohamed, T.M.1    Oceandy, D.2    Prehar, S.3    Alatwi, N.4    Hegab, Z.5    Baudoin, F.M.6
  • 18
    • 1942436943 scopus 로고    scopus 로고
    • Increased neuronal nitric oxide synthase-derived NO production in the failing human heart
    • DOI 10.1016/S0140-6736(04)16048-0, PII S0140673604160480
    • Damy T, Ratajczak P, Shah AM, Camors E, Marty I, Hasenfuss G et al. Increased neuronal nitric oxide synthase-derived NO production in the failing human heart. Lancet 2004;363:1365-1367. (Pubitemid 38529877)
    • (2004) Lancet , vol.363 , Issue.9418 , pp. 1365-1367
    • Damy, T.1    Ratajczak, P.2    Shah, A.M.3    Camors, E.4    Marty, I.5    Hasenfuss, G.6    Marotte, F.7    Samuel, J.-L.8    Heymes, C.9
  • 19
    • 33644875411 scopus 로고    scopus 로고
    • NNOS gene deletion exacerbates pathological left ventricular remodeling and functional deterioration after myocardial infarction
    • DOI 10.1161/CIRCULATIONAHA.105.539437, PII 0000301720051213000012
    • Dawson D, Lygate CA, Zhang MH, Hulbert K, Neubauer S, Casadei B. nNOS gene deletion exacerbates pathological left ventricular remodeling and functional deterioration after myocardial infarction. Circulation 2005;112:3729-3737. (Pubitemid 43739513)
    • (2005) Circulation , vol.112 , Issue.24 , pp. 3729-3737
    • Dawson, D.1    Lygate, C.A.2    Zhang, M.-H.3    Hulbert, K.4    Neubauer, S.5    Casadei, B.6
  • 20
    • 33644873609 scopus 로고    scopus 로고
    • Deficiency of neuronal nitric oxide synthase increases mortality and cardiac remodeling after myocardial infarction: Role of nitroso-redox equilibrium
    • DOI 10.1161/CIRCULATIONAHA.105.557892, PII 0000301720051129000011
    • Saraiva RM, Minhas KM, Raju SV, Barouch LA, Pitz E, Schuleri KH et al. Deficiency of neuronal nitric oxide synthase increases mortality and cardiac remodeling after myocardial infarction: role of nitroso-redox equilibrium. Circulation 2005;112: 3415-3422. (Pubitemid 43739556)
    • (2005) Circulation , vol.112 , Issue.22 , pp. 3415-3422
    • Saraiva, R.M.1    Minhas, K.M.2    Raju, S.V.Y.3    Barouch, L.A.4    Pitz, E.5    Schuleri, K.H.6    Vandegaer, K.7    Li, D.8    Hare, J.M.9
  • 21
    • 78049506757 scopus 로고    scopus 로고
    • Conditional overexpression of neuronal nitric oxide synthase is cardioprotective in ischemia/reperfusion
    • Burkard N, Williams T, Czolbe M, Blomer N, Panther F, Link M et al. Conditional overexpression of neuronal nitric oxide synthase is cardioprotective in ischemia/reperfusion. Circulation 2010;122:1588-1603.
    • (2010) Circulation , vol.122 , pp. 1588-1603
    • Burkard, N.1    Williams, T.2    Czolbe, M.3    Blomer, N.4    Panther, F.5    Link, M.6
  • 23
    • 0037059465 scopus 로고    scopus 로고
    • Cardiac-specific overexpression of inducible nitric oxide synthase does not result in severe cardiac dysfunction
    • DOI 10.1161/hh0102.102757
    • Heger J, Godecke A, Flogel U, Merx MW, Molojavyi A, Kuhn-Velten WN et al. Cardiac-specific overexpression of inducible nitric oxide synthase does not result in severe cardiac dysfunction. Circ Res 2002;90:93-99. (Pubitemid 34074614)
    • (2002) Circulation Research , vol.90 , Issue.1 , pp. 93-99
    • Heger, J.1    Godecke, A.2    Flogel, U.3    Merx, M.W.4    Molojavyi, A.5    Kuhn-Velten, W.N.6    Schrader, J.7
  • 24
    • 0038463819 scopus 로고    scopus 로고
    • Acute inhibition of myoglobin impairs contractility and energy state of iNOS-overexpressing hearts
    • DOI 10.1161/01.RES.0000079026.70629.E5
    • Wunderlich C, Flogel U, Godecke A, Heger J, Schrader J. Acute inhibition of myoglobin impairs contractility and energy state of iNOS-overexpressing hearts. Circ Res 2003;92:1352-1358. (Pubitemid 36773478)
    • (2003) Circulation Research , vol.92 , Issue.12 , pp. 1352-1358
    • Wunderlich, C.1    Flogel, U.2    Godecke, A.3    Heger, J.4    Schrader, J.5
  • 25
    • 0035822692 scopus 로고    scopus 로고
    • Increased inducible nitric oxide synthase expression contributes to myocardial dysfunction and higher mortality after myocardial infarction in mice
    • Feng Q, Lu X, Jones DL, Shen J, Arnold JM. Increased inducible nitric oxide synthase expression contributes to myocardial dysfunction and higher mortality after myocardial infarction in mice. Circulation 2001;104:700-704. (Pubitemid 32738526)
    • (2001) Circulation , vol.104 , Issue.6 , pp. 700-704
    • Feng, Q.1    Lu, X.2    Jones, D.L.3    Shen, J.4    Arnold, J.M.O.5
  • 32
    • 0037080553 scopus 로고    scopus 로고
    • Role of myocardial inducible nitric oxide synthase in contractile dysfunction and β-adrenergic hyporesponsiveness in rats with experimental volume-overload heart failure
    • DOI 10.1161/hc0202.102015
    • Gealekman O, Abassi Z, Rubinstein I, Winaver J, Binah O. Role of myocardial inducible nitric oxide synthase in contractile dysfunction and b-adrenergic hyporesponsiveness in rats with experimental volume-overload heart failure. Circulation 2002; 105:236-243. (Pubitemid 34084325)
    • (2002) Circulation , vol.105 , Issue.2 , pp. 236-243
    • Gealekman, O.1    Abassi, Z.2    Rubinstein, I.3    Winaver, J.4    Binah, O.5
  • 34
    • 1942534531 scopus 로고    scopus 로고
    • 2+ Transients
    • DOI 10.1161/01.CIR.0000124231.98250.A8
    • Ziolo MT, Maier LS, Piacentino V III, Bossuyt J, Houser SR, Bers DM. Myocyte nitric oxide synthase 2 contributes to blunted b-adrenergic response in failing human hearts by decreasing Ca2+ transients. Circulation 2004;109:1886-1891. (Pubitemid 38509124)
    • (2004) Circulation , vol.109 , Issue.15 , pp. 1886-1891
    • Ziolo, M.T.1    Maier, L.S.2    Piacentino III, V.3    Bossuyt, J.4    Houser, S.R.5    Bers, D.M.6
  • 35
    • 0028135094 scopus 로고
    • Cytokine-inducible nitric oxide synthase (iNOS) expression in cardiac myocytes. Characterization and regulation of iNOS expression and detection of iNOS activity in single cardiac myocytes in vitro
    • Balligand JL, Ungureanu-Longrois D, Simmons WW, Pimental D, Malinski TA, Kapturczak M et al. Cytokine-inducible nitric oxide synthase (iNOS) expression in cardiac myocytes. Characterization and regulation of iNOS expression and detection of iNOS activity in single cardiac myocytes in vitro. J Biol Chem 1994;269: 27580-27588.
    • (1994) J Biol Chem , vol.269 , pp. 27580-27588
    • Balligand, J.L.1    Ungureanu-Longrois, D.2    Simmons, W.W.3    Pimental, D.4    Malinski, T.A.5    Kapturczak, M.6
  • 36
    • 54049090854 scopus 로고    scopus 로고
    • INOS in cardiac myocytes plays a critical role in death in a murine model of hypertrophy induced by calcineurin
    • Somers JR, Beck PL, Lees-Miller JP, Roach D, Li Y, Guo J et al. iNOS in cardiac myocytes plays a critical role in death in a murine model of hypertrophy induced by calcineurin. Am J Physiol Heart Circ Physiol 2008;295:H1122-H1131.
    • (2008) Am J Physiol Heart Circ Physiol , vol.295
    • Somers, J.R.1    Beck, P.L.2    Lees-Miller, J.P.3    Roach, D.4    Li, Y.5    Guo, J.6
  • 37
    • 29444432915 scopus 로고    scopus 로고
    • The ubiquitous role of nitric oxide in cardioprotection
    • DOI 10.1016/j.yjmcc.2005.09.011, PII S0022282805002919
    • Jones SP, Bolli R. The ubiquitous role of nitric oxide in cardioprotection. J Mol Cell Cardiol 2006;40:16-23. (Pubitemid 43012113)
    • (2006) Journal of Molecular and Cellular Cardiology , vol.40 , Issue.1 , pp. 16-23
    • Jones, S.P.1    Bolli, R.2
  • 38
    • 2142828491 scopus 로고    scopus 로고
    • COX-2 and iNOS in opioid-induced delayed cardioprotection in the intact rat
    • DOI 10.1016/j.lfs.2003.10.036, PII S0024320504002218
    • Patel HH, Hsu AK, Gross GJ. COX-2 and iNOS in opioid-induced delayed cardioprotection in the intact rat. Life Sci 2004;75:129-140. (Pubitemid 38553870)
    • (2004) Life Sciences , vol.75 , Issue.2 , pp. 129-140
    • Patel, H.H.1    Hsu, A.K.2    Gross, G.J.3
  • 39
    • 57149142916 scopus 로고    scopus 로고
    • Cardiac myocyte-specific expression of inducible nitric oxide synthase protects against ischemia/reperfusion injury by preventing mitochondrial permeability transition
    • West MB, Rokosh G, Obal D, Velayutham M, Xuan YT, Hill BG et al. Cardiac myocyte-specific expression of inducible nitric oxide synthase protects against ischemia/reperfusion injury by preventing mitochondrial permeability transition. Circulation 2008;118:1970-1978.
    • (2008) Circulation , vol.118 , pp. 1970-1978
    • West, M.B.1    Rokosh, G.2    Obal, D.3    Velayutham, M.4    Xuan, Y.T.5    Hill, B.G.6
  • 40
    • 7544231821 scopus 로고    scopus 로고
    • Cardiomyocyte-restricted overexpression of endothelial nitric oxide synthase (NOS3) attenuates β-adrenergic stimulation and reinforces vagal inhibition of cardiac contraction
    • DOI 10.1161/01.CIR.0000145608.80855.BC
    • Massion PB, Dessy C, Desjardins F, Pelat M, Havaux X, Belge C et al. Cardiomyocyte-restricted overexpression of endothelial nitric oxide synthase (NOS3) attenuates b-adrenergic stimulation and reinforces vagal inhibition of cardiac contraction. Circulation 2004;110:2666-2672. (Pubitemid 39453017)
    • (2004) Circulation , vol.110 , Issue.17 , pp. 2666-2672
    • Massion, P.B.1    Dessy, C.2    Desjardins, F.3    Pelat, M.4    Havaux, X.5    Belge, C.6    Moulin, P.7    Guiot, Y.8    Feron, O.9    Janssens, S.10    Balligand, J.-L.11
  • 44
    • 19444372119 scopus 로고    scopus 로고
    • Concentric left ventricular remodeling in endothelial nitric oxide synthase knockout mice by chronic pressure overload
    • DOI 10.1016/j.cardiores.2005.01.021, PII S0008636305000696
    • Ruetten H, Dimmeler S, Gehring D, Ihling C, Zeiher AM. Concentric left ventricular remodeling in endothelial nitric oxide synthase knockout mice by chronic pressure overload. Cardiovasc Res 2005;66:444-453. (Pubitemid 40725756)
    • (2005) Cardiovascular Research , vol.66 , Issue.3 , pp. 444-453
    • Ruetten, H.1    Dimmeler, S.2    Gehring, D.3    Ihling, C.4    Zeiher, A.M.5
  • 50
    • 47649122637 scopus 로고    scopus 로고
    • Reversal of cardiac hypertrophy and fibrosis from pressure overload by tetrahydrobiopterin: Efficacy of recoupling nitric oxide synthase as a therapeutic strategy
    • Moens AL, Takimoto E, Tocchetti CG, Chakir K, Bedja D, Cormaci G et al. Reversal of cardiac hypertrophy and fibrosis from pressure overload by tetrahydrobiopterin: efficacy of recoupling nitric oxide synthase as a therapeutic strategy. Circulation 2008; 117:2626-2636.
    • (2008) Circulation , vol.117 , pp. 2626-2636
    • Moens, A.L.1    Takimoto, E.2    Tocchetti, C.G.3    Chakir, K.4    Bedja, D.5    Cormaci, G.6
  • 51
    • 79551582218 scopus 로고    scopus 로고
    • Reversal of inducible nitric oxide synthase uncoupling unmasks tolerance to ischemia/reperfusion injury in the diabetic rat heart
    • Okazaki T, Otani H, Shimazu T, Yoshioka K, Fujita M, Katano T et al. Reversal of inducible nitric oxide synthase uncoupling unmasks tolerance to ischemia/reperfusion injury in the diabetic rat heart. J Mol Cell Cardiol 2011;50:534-544.
    • (2011) J Mol Cell Cardiol , vol.50 , pp. 534-544
    • Okazaki, T.1    Otani, H.2    Shimazu, T.3    Yoshioka, K.4    Fujita, M.5    Katano, T.6
  • 52
    • 79961062184 scopus 로고    scopus 로고
    • Towards a re-definition of 'cardiac hypertrophy' through a rational characterization of left ventricular phenotypes: A position paper of the Working Group 'Myocardial Function' of the ESC
    • Knoll R, Iaccarino G, Tarone G, Hilfiker-Kleiner D, Bauersachs J, Leite-Moreira AF et al. Towards a re-definition of 'cardiac hypertrophy' through a rational characterization of left ventricular phenotypes: a position paper of the Working Group 'Myocardial Function' of the ESC. Eur J Heart Fail 2011;13:811-819.
    • (2011) Eur J Heart Fail , vol.13 , pp. 811-819
    • Knoll, R.1    Iaccarino, G.2    Tarone, G.3    Hilfiker-Kleiner, D.4    Bauersachs, J.5    Leite-Moreira, A.F.6
  • 53
    • 0032519668 scopus 로고    scopus 로고
    • Nitric oxide, atrial natriuretic peptide, and cyclic GMP inhibit the growth-promoting effects of norepinephrine in cardiac myocytes and fibroblasts
    • Calderone A, Thaik CM, Takahashi N, Chang DL, Colucci WS. Nitric oxide, atrial natriuretic peptide, and cyclic GMP inhibit the growth-promoting effects of norepinephrine in cardiac myocytes and fibroblasts. J Clin Invest 1998;101:812-818. (Pubitemid 28096078)
    • (1998) Journal of Clinical Investigation , vol.101 , Issue.4 , pp. 812-818
    • Calderone, A.1    Thaik, C.M.2    Takahashi, N.3    Chang, D.L.F.4    Colucci, W.S.5
  • 56
    • 1542409908 scopus 로고    scopus 로고
    • Altered Calcium Handling Is Critically Involved in the Cardiotoxic Effects of Chronic β-Adrenergic Stimulation
    • DOI 10.1161/01.CIR.0000117254.68497.39
    • Engelhardt S, Hein L, Dyachenkow V, Kranias EG, Isenberg G, Lohse MJ. Altered calcium handling is critically involved in the cardiotoxic effects of chronic b-adrenergic stimulation. Circulation 2004;109:1154-1160. (Pubitemid 38332620)
    • (2004) Circulation , vol.109 , Issue.9 , pp. 1154-1160
    • Engelhardt, S.1    Hein, L.2    Dyachenkow, V.3    Kranias, E.G.4    Isenberg, G.5    Lohse, M.J.6
  • 57
    • 61949419029 scopus 로고    scopus 로고
    • Ca2+ signaling domains responsible for cardiac hypertrophy and arrhythmias
    • Houser SR. Ca2+ signaling domains responsible for cardiac hypertrophy and arrhythmias. Circ Res 2009;104:413-415.
    • (2009) Circ Res , vol.104 , pp. 413-415
    • Houser, S.R.1
  • 58
    • 77949274491 scopus 로고    scopus 로고
    • Cyclic GMP/PKG-dependent inhibition of TRPC6 channel activity and expression negatively regulates cardiomyocyte NFAT activation: Novel mechanism of cardiac stress modulation by PDE5 inhibition
    • Koitabashi N, Aiba T, Hesketh GG, Rowell J, Zhang M, Takimoto E et al. Cyclic GMP/PKG-dependent inhibition of TRPC6 channel activity and expression negatively regulates cardiomyocyte NFAT activation: novel mechanism of cardiac stress modulation by PDE5 inhibition. J Mol Cell Cardiol 2010;48:713-724.
    • (2010) J Mol Cell Cardiol , vol.48 , pp. 713-724
    • Koitabashi, N.1    Aiba, T.2    Hesketh, G.G.3    Rowell, J.4    Zhang, M.5    Takimoto, E.6
  • 59
    • 72849138699 scopus 로고    scopus 로고
    • A1G-dependent T-type Ca2+ current antagonizes cardiac hypertrophy through a NOS3-dependent mechanism in mice
    • Nakayama H, Bodi I, Correll RN, Chen X, Lorenz J, Houser SR et al. a1G-dependent T-type Ca2+ current antagonizes cardiac hypertrophy through a NOS3-dependent mechanism in mice. J Clin Invest 2009;119:3787-3796.
    • (2009) J Clin Invest , vol.119 , pp. 3787-3796
    • Nakayama, H.1    Bodi, I.2    Correll, R.N.3    Chen, X.4    Lorenz, J.5    Houser, S.R.6
  • 60
    • 77950377332 scopus 로고    scopus 로고
    • Cardiac hypertrophy is not amplified by deletion of cGMP-dependent protein kinase i in cardiomyocytes
    • Lukowski R, Rybalkin SD, Loga F, Leiss V, Beavo JA, Hofmann F. Cardiac hypertrophy is not amplified by deletion of cGMP-dependent protein kinase I in cardiomyocytes. Proc Natl Acad Sci USA 2010;107:5646-5651.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 5646-5651
    • Lukowski, R.1    Rybalkin, S.D.2    Loga, F.3    Leiss, V.4    Beavo, J.A.5    Hofmann, F.6
  • 61
    • 84856014109 scopus 로고    scopus 로고
    • CGMP-dependent protein kinase i alpha is required for suppression of cardiac remodeling and controls early JNK activation in the heart after pressure overload
    • Blanton RM, Takimoto E, Aronovitz M, Lane AM, Karas R, Mendelsohn ME et al. cGMP-dependent protein kinase I alpha is required for suppression of cardiac remodeling and controls early JNK activation in the heart after pressure overload. Circulation 2010;122:A20875.
    • (2010) Circulation , vol.122
    • Blanton, R.M.1    Takimoto, E.2    Aronovitz, M.3    Lane, A.M.4    Karas, R.5    Mendelsohn, M.E.6    Al., T.7
  • 62
    • 77952749684 scopus 로고    scopus 로고
    • PDE5A suppression of acute b-adrenergic activation requires modulation of myocyte beta-3 signaling coupled to PKG-mediated troponin i phosphorylation
    • Lee DI, Vahebi S, Tocchetti CG, Barouch LA, Solaro RJ, Takimoto E et al. PDE5A suppression of acute b-adrenergic activation requires modulation of myocyte beta-3 signaling coupled to PKG-mediated troponin I phosphorylation. Basic Res Cardiol 2010;105:337-347.
    • (2010) Basic Res Cardiol , vol.105 , pp. 337-347
    • Lee, D.I.1    Vahebi, S.2    Tocchetti, C.G.3    Barouch, L.A.4    Solaro, R.J.5    Takimoto, E.6
  • 64
    • 77956520622 scopus 로고    scopus 로고
    • Impaired S-nitrosylation of the ryanodine receptor caused by xanthine oxidase activity contributes to calcium leak in heart failure
    • Gonzalez DR, Treuer AV, Castellanos J, Dulce RA, Hare JM. Impaired S-nitrosylation of the ryanodine receptor caused by xanthine oxidase activity contributes to calcium leak in heart failure. J Biol Chem 2010;285:28938-28945.
    • (2010) J Biol Chem , vol.285 , pp. 28938-28945
    • Gonzalez, D.R.1    Treuer, A.V.2    Castellanos, J.3    Dulce, R.A.4    Hare, J.M.5
  • 66
    • 70349466515 scopus 로고    scopus 로고
    • Protein denitrosylation: Enzymatic mechanisms and cellular functions
    • Benhar M, Forrester MT, Stamler JS. Protein denitrosylation: enzymatic mechanisms and cellular functions. Nat Rev Mol Cell Biol 2009;10:721-732.
    • (2009) Nat Rev Mol Cell Biol , vol.10 , pp. 721-732
    • Benhar, M.1    Forrester, M.T.2    Stamler, J.S.3
  • 68
    • 79952070504 scopus 로고    scopus 로고
    • Simultaneous measurement of protein oxidation and S-nitrosylation during preconditioning and ischemia/reperfusion injury with resin-assisted capture
    • Kohr MJ, Sun J, Aponte A, Wang G, Gucek M, Murphy E et al. Simultaneous measurement of protein oxidation and S-nitrosylation during preconditioning and ischemia/reperfusion injury with resin-assisted capture. Circ Res 2011;108:418-426.
    • (2011) Circ Res , vol.108 , pp. 418-426
    • Kohr, M.J.1    Sun, J.2    Aponte, A.3    Wang, G.4    Gucek, M.5    Murphy, E.6
  • 69
    • 70349730049 scopus 로고    scopus 로고
    • Neuronal nitric oxide synthase protects against myocardial infarction-induced ventricular arrhythmia and mortality in mice
    • Burger DE, Lu X, Lei M, Xiang FL, Hammoud L, Jiang M et al. Neuronal nitric oxide synthase protects against myocardial infarction-induced ventricular arrhythmia and mortality in mice. Circulation 2009;120:1345-1354.
    • (2009) Circulation , vol.120 , pp. 1345-1354
    • Burger, D.E.1    Lu, X.2    Lei, M.3    Xiang, F.L.4    Hammoud, L.5    Jiang, M.6
  • 70
    • 0035805565 scopus 로고    scopus 로고
    • S-nitrosation controls gating and conductance of the a1 subunit of class C L-type Ca2+ channels
    • Poteser M, Romanin C, Schreibmayer W, Mayer B, Groschner K. S-nitrosation controls gating and conductance of the a1 subunit of class C L-type Ca2+ channels. J Biol Chem 2001;276:14797-14803.
    • (2001) J Biol Chem , vol.276 , pp. 14797-14803
    • Poteser, M.1    Romanin, C.2    Schreibmayer, W.3    Mayer, B.4    Groschner, K.5
  • 71
    • 33646813330 scopus 로고    scopus 로고
    • Hypercontractile female hearts exhibit increased S-nitrosylation of the L-type Ca2+ channel a1 subunit and reduced ischemia/reperfusion injury
    • Sun J, Picht E, Ginsburg KS, Bers DM, Steenbergen C, Murphy E. Hypercontractile female hearts exhibit increased S-nitrosylation of the L-type Ca2+ channel a1 subunit and reduced ischemia/reperfusion injury. Circ Res 2006;98:403-411.
    • (2006) Circ Res , vol.98 , pp. 403-411
    • Sun, J.1    Picht, E.2    Ginsburg, K.S.3    Bers, D.M.4    Steenbergen, C.5    Murphy, E.6
  • 72
    • 36348964192 scopus 로고    scopus 로고
    • Preconditioning results in S-nitrosylation of proteins involved in regulation of mitochondrial energetics and calcium transport
    • DOI 10.1161/CIRCRESAHA.107.155879
    • Sun J, Morgan M, Shen RF, Steenbergen C, Murphy E. Preconditioning results in S-nitrosylation of proteins involved in regulation of mitochondrial energetics and calcium transport. Circ Res 2007;101:1155-1163. (Pubitemid 350146442)
    • (2007) Circulation Research , vol.101 , Issue.11 , pp. 1155-1163
    • Sun, J.1    Morgan, M.2    Shen, R.-F.3    Steenbergen, C.4    Murphy, E.5
  • 73
    • 38049134302 scopus 로고    scopus 로고
    • Deficient ryanodine receptor S-nitrosylation increases sarcoplasmic reticulum calcium leak and arrhythmogenesis in cardiomyocytes
    • Gonzalez DR, Beigi F, Treuer AV, Hare JM. Deficient ryanodine receptor S-nitrosylation increases sarcoplasmic reticulum calcium leak and arrhythmogenesis in cardiomyocytes. Proc Natl Acad Sci USA 2007;104:20612-20617.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 20612-20617
    • Gonzalez, D.R.1    Beigi, F.2    Treuer, A.V.3    Hare, J.M.4
  • 74
    • 72749098828 scopus 로고    scopus 로고
    • Phospholamban Snitrosylation modulates Starling response in fish heart
    • Garofalo F, Parisella ML, Amelio D, Tota B, Imbrogno S. Phospholamban Snitrosylation modulates Starling response in fish heart. Proc Biol Sci 2009;276: 4043-4052.
    • (2009) Proc Biol Sci , vol.276 , pp. 4043-4052
    • Garofalo, F.1    Parisella, M.L.2    Amelio, D.3    Tota, B.4    Imbrogno, S.5
  • 75
    • 77956254104 scopus 로고    scopus 로고
    • Redox signaling in inflammation: Interactions of endogenous electrophiles and mitochondria in cardiovascular disease
    • Koenitzer JR, Freeman BA. Redox signaling in inflammation: interactions of endogenous electrophiles and mitochondria in cardiovascular disease. Ann N Y Acad Sci 2010; 1203:45-52.
    • (2010) Ann N y Acad Sci , vol.1203 , pp. 45-52
    • Koenitzer, J.R.1    Freeman, B.A.2
  • 76
    • 72049108435 scopus 로고    scopus 로고
    • Endogenous generation and protective effects of nitro-fatty acids in a murine model of focal cardiac ischaemia and reperfusion
    • Rudolph V, Rudolph TK, Schopfer FJ, Bonacci G, Woodcock SR, Cole MP et al. Endogenous generation and protective effects of nitro-fatty acids in a murine model of focal cardiac ischaemia and reperfusion. Cardiovasc Res 2010;85:155-166.
    • (2010) Cardiovasc Res , vol.85 , pp. 155-166
    • Rudolph, V.1    Rudolph, T.K.2    Schopfer, F.J.3    Bonacci, G.4    Woodcock, S.R.5    Cole, M.P.6
  • 77
    • 60549098959 scopus 로고    scopus 로고
    • Ventricular phosphodiesterase-5 expression is increased in patients with advanced heart failure and contributes to adverse ventricular remodeling after myocardial infarction in mice
    • Pokreisz P, Vandenwijngaert S, Bito V, Van den Bergh A, Lenaerts I, Busch C et al. Ventricular phosphodiesterase-5 expression is increased in patients with advanced heart failure and contributes to adverse ventricular remodeling after myocardial infarction in mice. Circulation 2009;119:408-416.
    • (2009) Circulation , vol.119 , pp. 408-416
    • Pokreisz, P.1    Vandenwijngaert, S.2    Bito, V.3    Van Den Bergh, A.4    Lenaerts, I.5    Busch, C.6
  • 78
    • 70349085833 scopus 로고    scopus 로고
    • CGMP-hydrolytic activity and its inhibition by sildenafil in normal and failing human and mouse myocardium
    • Vandeput F, Krall J, Ockaili R, Salloum FN, Florio V, Corbin JD et al. cGMP-hydrolytic activity and its inhibition by sildenafil in normal and failing human and mouse myocardium. J Pharmacol Exp Ther 2009;330:884-891.
    • (2009) J Pharmacol Exp Ther , vol.330 , pp. 884-891
    • Vandeput, F.1    Krall, J.2    Ockaili, R.3    Salloum, F.N.4    Florio, V.5    Corbin, J.D.6
  • 79
    • 69649087375 scopus 로고    scopus 로고
    • Pharmacological activation of soluble guanylate cyclase protects the heart against ischemic injury
    • Korkmaz S, Radovits T, Barnucz E, Hirschberg K, Neugebauer P, Loganathan S et al. Pharmacological activation of soluble guanylate cyclase protects the heart against ischemic injury. Circulation 2009;120:677-686.
    • (2009) Circulation , vol.120 , pp. 677-686
    • Korkmaz, S.1    Radovits, T.2    Barnucz, E.3    Hirschberg, K.4    Neugebauer, P.5    Loganathan, S.6
  • 80
    • 67650094306 scopus 로고    scopus 로고
    • BAY 58-2667, a nitric oxide-independent guanylyl cyclase activator, pharmacologically post-conditions rabbit and rat hearts
    • Krieg T, Liu Y, Rutz T, Methner C, Yang XM, Dost T et al. BAY 58-2667, a nitric oxide-independent guanylyl cyclase activator, pharmacologically post-conditions rabbit and rat hearts. Eur Heart J 2009;30:1607-1613.
    • (2009) Eur Heart J , vol.30 , pp. 1607-1613
    • Krieg, T.1    Liu, Y.2    Rutz, T.3    Methner, C.4    Yang, X.M.5    Dost, T.6
  • 81
    • 67649229211 scopus 로고    scopus 로고
    • Cinaciguat (BAY 58-2667) improves cardiopulmonary hemodynamics in patients with acute decompensated heart failure
    • Lapp H, Mitrovic V, Franz N, Heuer H, Buerke M, Wolfertz J et al. Cinaciguat (BAY 58-2667) improves cardiopulmonary hemodynamics in patients with acute decompensated heart failure. Circulation 2009;119:2781-2788.
    • (2009) Circulation , vol.119 , pp. 2781-2788
    • Lapp, H.1    Mitrovic, V.2    Franz, N.3    Heuer, H.4    Buerke, M.5    Wolfertz, J.6
  • 82
    • 79960599350 scopus 로고    scopus 로고
    • Soluble guanylate cyclase stimulation prevents fibrotic tissue remodeling and improves survival in salt-sensitive Dahl rats
    • Geschka S, Kretschmer A, Sharkovska Y, Evgenov OV, Lawrenz B, Hucke A et al. Soluble guanylate cyclase stimulation prevents fibrotic tissue remodeling and improves survival in salt-sensitive Dahl rats. PLoS One 2011;6:e21853.
    • (2011) PLoS One , vol.6
    • Geschka, S.1    Kretschmer, A.2    Sharkovska, Y.3    Evgenov, O.V.4    Lawrenz, B.5    Hucke, A.6
  • 83
    • 0035806914 scopus 로고    scopus 로고
    • Folic acid prevents nitroglycerin-induced nitric oxide synthase dysfunction and nitrate tolerance: A human in vivo study
    • Gori T, Burstein JM, Ahmed S, Miner SE, Al-Hesayen A, Kelly S et al. Folic acid prevents nitroglycerin-induced nitric oxide synthase dysfunction and nitrate tolerance: a human in vivo study. Circulation 2001;104:1119-1123. (Pubitemid 32830394)
    • (2001) Circulation , vol.104 , Issue.10 , pp. 1119-1123
    • Gori, T.1    Burstein, J.M.2    Ahmed, S.3    Miner, S.E.S.4    Al-Hesayen, A.5    Kelly, S.6    Parker, J.D.7
  • 88
    • 77957372042 scopus 로고    scopus 로고
    • Beta3-adrenergic receptors in cardiac and vascular tissues: Emerging concepts and therapeutic perspectives
    • Dessy C, Balligand JL. Beta3-adrenergic receptors in cardiac and vascular tissues: emerging concepts and therapeutic perspectives. Adv Pharmacol 2010;59:135-163.
    • (2010) Adv Pharmacol , vol.59 , pp. 135-163
    • Dessy, C.1    Balligand, J.L.2
  • 89
    • 80055060619 scopus 로고    scopus 로고
    • Beta-3 adrenoceptors as new therapeutic targets for cardiovascular pathologies
    • Gauthier C, Rozec B, Manoury B, Balligand JL. Beta-3 adrenoceptors as new therapeutic targets for cardiovascular pathologies. Curr Heart Fail Rep 2011;8:184-192.
    • (2011) Curr Heart Fail Rep , vol.8 , pp. 184-192
    • Gauthier, C.1    Rozec, B.2    Manoury, B.3    Balligand, J.L.4
  • 90
    • 0035957302 scopus 로고    scopus 로고
    • 3-adrenoceptors and altered contractile response to inotropic amines in human failing myocardium
    • Moniotte S, Kobzik L, Feron O, Trochu JN, Gauthier C, Balligand JL. Upregulation of b3-adrenoceptors and altered contractile response to inotropic amines in human failing myocardium. Circulation 2001;103:1649-1655. (Pubitemid 32246612)
    • (2001) Circulation , vol.103 , Issue.12 , pp. 1649-1655
    • Moniotte, S.1    Kobzik, L.2    Feron, O.3    Trochu, J.-N.4    Gauthier, C.5    Balligand, J.-L.6
  • 91
    • 84856013301 scopus 로고    scopus 로고
    • Human beta-3 adrenoreceptor over-expression inhibits neurohormones- induced cardiac hypertrophy in vitro and in vivo
    • Hammond J, Balligand JL. Human beta-3 adrenoreceptor over-expression inhibits neurohormones-induced cardiac hypertrophy in vitro and in vivo. Cardiovasc Res 2010;87:S91.
    • (2010) Cardiovasc Res , vol.87
    • Hammond, J.1    Balligand, J.L.2
  • 92
    • 0035856512 scopus 로고    scopus 로고
    • 3-adrenergic receptor overexpressed in the hearts of transgenic mice
    • Kohout TA, Takaoka H, McDonald PH, Perry SJ, Mao L, Lefkowitz RJ et al. Augmentation of cardiac contractility mediated by the human b3-adrenergic receptor overexpressed in the hearts of transgenic mice. Circulation 2001;104:2485-2491. (Pubitemid 33108385)
    • (2001) Circulation , vol.104 , Issue.20 , pp. 2485-2491
    • Kohout, T.A.1    Takaoka, H.2    McDonald, P.H.3    Perry, S.J.4    Mao, L.5    Lefkowitz, R.J.6    Rockman, H.A.7
  • 93
    • 70349755909 scopus 로고    scopus 로고
    • Adverse ventricular remodeling and exacerbated NOS uncoupling from pressure-overload in mice lacking the b3-adrenoreceptor
    • Moens AL, Leyton-Mange JS, Niu X, Yang R, Cingolani O, Arkenbout EK et al. Adverse ventricular remodeling and exacerbated NOS uncoupling from pressure-overload in mice lacking the b3-adrenoreceptor. J Mol Cell Cardiol 2009; 47:576-585.
    • (2009) J Mol Cell Cardiol , vol.47 , pp. 576-585
    • Moens, A.L.1    Leyton-Mange, J.S.2    Niu, X.3    Yang, R.4    Cingolani, O.5    Arkenbout, E.K.6
  • 94
    • 79958792472 scopus 로고    scopus 로고
    • Exercise protects against myocardial ischemia-reperfusion injury via stimulation of b3-adrenergic receptors and increased nitric oxide signaling: Role of nitrite and nitrosothiols
    • Calvert JW, Condit ME, Aragon JP, Nicholson CK, Moody BF, Hood RL et al. Exercise protects against myocardial ischemia-reperfusion injury via stimulation of b3-adrenergic receptors and increased nitric oxide signaling: role of nitrite and nitrosothiols. Circ Res 2011;108:1448-1458.
    • (2011) Circ Res , vol.108 , pp. 1448-1458
    • Calvert, J.W.1    Condit, M.E.2    Aragon, J.P.3    Nicholson, C.K.4    Moody, B.F.5    Hood, R.L.6
  • 95
    • 78650703662 scopus 로고    scopus 로고
    • B3 adrenergic stimulation of the cardiac Na+-K+ pump by reversal of an inhibitory oxidative modification
    • Bundgaard H, Liu CC, Garcia A, Hamilton EJ, Huang Y, Chia KK et al. b3 adrenergic stimulation of the cardiac Na+-K+ pump by reversal of an inhibitory oxidative modification. Circulation 2010;122:2699-2708.
    • (2010) Circulation , vol.122 , pp. 2699-2708
    • Bundgaard, H.1    Liu, C.C.2    Garcia, A.3    Hamilton, E.J.4    Huang, Y.5    Chia, K.K.6
  • 98
    • 64749105265 scopus 로고    scopus 로고
    • Nebivolol, a vasodilating selective b1-blocker, is a b3-adrenoceptor agonist in the nonfailing transplanted human heart
    • Rozec B, Erfanian M, Laurent K, Trochu JN, Gauthier C. Nebivolol, a vasodilating selective b1-blocker, is a b3-adrenoceptor agonist in the nonfailing transplanted human heart. J Am Coll Cardiol 2009;53:1532-1538.
    • (2009) J Am Coll Cardiol , vol.53 , pp. 1532-1538
    • Rozec, B.1    Erfanian, M.2    Laurent, K.3    Trochu, J.N.4    Gauthier, C.5
  • 99
    • 79251518319 scopus 로고    scopus 로고
    • Nebivolol exerts beneficial effects on endothelial function, early endothelial progenitor cells, myocardial neovascularization, and left ventricular dysfunction early after myocardial infarction beyond conventional b1-blockade
    • Sorrentino SA, Doerries C, Manes C, Speer T, Dessy C, Lobysheva I et al. Nebivolol exerts beneficial effects on endothelial function, early endothelial progenitor cells, myocardial neovascularization, and left ventricular dysfunction early after myocardial infarction beyond conventional b1-blockade. J Am Coll Cardiol 2011;57:601-611.
    • (2011) J Am Coll Cardiol , vol.57 , pp. 601-611
    • Sorrentino, S.A.1    Doerries, C.2    Manes, C.3    Speer, T.4    Dessy, C.5    Lobysheva, I.6
  • 101
    • 0027225229 scopus 로고
    • Abnormal contractile function due to induction of nitric oxide synthesis in rat cardiac myocytes follows exposure to activated macrophage-conditioned medium
    • Balligand JL, Ungureanu D, Kelly RA, Kobzik L, Pimental D, Michel T et al. Abnormal contractile function due to induction of nitric oxide synthesis in rat cardiac myocytes follows exposure to activated macrophage-conditioned medium. J Clin Invest 1993; 91:2314-2319. (Pubitemid 23141511)
    • (1993) Journal of Clinical Investigation , vol.91 , Issue.5 , pp. 2314-2319
    • Balligand, J.-L.1    Ungureanu, D.2    Kelly, R.A.3    Kobzik, L.4    Pimental, D.5    Michel, T.6    Smith, T.W.7
  • 102
    • 0037459638 scopus 로고    scopus 로고
    • Cardiac neuronal nitric oxide synthase isoform regulates myocardial contraction and calcium handling
    • Sears CE, Bryant SM, Ashley EA, Lygate CA, Rakovic S,Wallis HL et al. Cardiac neuronal nitric oxide synthase isoform regulates myocardial contraction and calcium handling. Circ Res 2003;92:e52-e59.
    • (2003) Circ Res , vol.92
    • Sears, C.E.1    Bryant, S.M.2    Ashley, E.A.3    Lygate, C.A.4    Rakovic Swallis, H.L.5
  • 103
    • 0037149489 scopus 로고    scopus 로고
    • Nitric oxide regulates the heart by spatial confinement of nitric oxide synthase isoforms
    • Barouch LA, Harrison RW, Skaf MW, Rosas GO, Cappola TP, Kobeissi ZA et al. Nitric oxide regulates the heart by spatial confinement of nitric oxide synthase isoforms. Nature 2002;416:337-339.
    • (2002) Nature , vol.416 , pp. 337-339
    • Barouch, L.A.1    Harrison, R.W.2    Skaf, M.W.3    Rosas, G.O.4    Cappola, T.P.5    Kobeissi, Z.A.6
  • 106
    • 0030777615 scopus 로고    scopus 로고
    • The protective effect of late preconditioning against myocardial stunning in conscious rabbits is mediated by nitric oxide synthase: Evidence that nitric oxide acts both as a trigger and as a mediator of the late phase of ischemic preconditioning
    • Bolli R, Manchikalapudi S, Tang XL, Takano H, Qiu Y, Guo Y et al. The protective effect of late preconditioning against myocardial stunning in conscious rabbits is mediated by nitric oxide synthase. Evidence that nitric oxide acts both as a trigger and as a mediator of the late phase of ischemic preconditioning. Circ Res 1997;81: 1094-1107. (Pubitemid 27514960)
    • (1997) Circulation Research , vol.81 , Issue.6 , pp. 1094-1107
    • Bolli, R.1    Manchikalapudi, S.2    Tang, X.-L.3    Takano, H.4    Qiu, Y.5    Guo, Y.6    Zhang, Q.7    Jadoon, A.K.8
  • 107
    • 16844382827 scopus 로고    scopus 로고
    • Phosphodiesterase-5 inhibitor sildenafil preconditions adult cardiac myocytes against necrosis and apoptosis. Essential role of nitric oxide signaling
    • Das A, Xi L, Kukreja RC. Phosphodiesterase-5 inhibitor sildenafil preconditions adult cardiac myocytes against necrosis and apoptosis. Essential role of nitric oxide signaling. J Biol Chem 2005;280:12944-12955.
    • (2005) J Biol Chem , vol.280 , pp. 12944-12955
    • Das, A.1    Xi, L.2    Kukreja, R.C.3
  • 108
    • 10744226444 scopus 로고    scopus 로고
    • Absence of inducible nitric oxide synthase reduces myocardial damage during ischemia reperfusion in streptozotocin-induced hyperglycemic mice
    • DOI 10.2337/diabetes.53.2.454
    • Marfella R, Di Filippo C, Esposito K, Nappo F, Piegari E, Cuzzocrea S et al. Absence of inducible nitric oxide synthase reduces myocardial damage during ischemia reperfusion in streptozotocin-induced hyperglycemic mice. Diabetes 2004;53:454-462. (Pubitemid 38174563)
    • (2004) Diabetes , vol.53 , Issue.2 , pp. 454-462
    • Marfella, R.1    Di Filippo, C.2    Esposito, K.3    Nappo, F.4    Piegari, E.5    Cuzzocrea, S.6    Berrino, L.7    Rossi, F.8    Giugliano, D.9    D'Amico, M.10
  • 109
    • 0036916084 scopus 로고    scopus 로고
    • Aminoguanidine inhibits mitogen-activated protein kinase and improves cardiac performance and cardiovascular remodeling in failing hearts of salt-sensitive hypertensive rats
    • DOI 10.1097/00004872-200212000-00028
    • Kobayashi N, Horinaka S, Mita S, Yoshida K, Honda T, Kobayashi T et al. Aminoguanidine inhibits mitogen-activated protein kinase and improves cardiac performance and cardiovascular remodeling in ailing hearts of salt-sensitive hypertensive rats. J Hypertens 2002;20:2475-2485. (Pubitemid 36026861)
    • (2002) Journal of Hypertension , vol.20 , Issue.12 , pp. 2475-2485
    • Kobayashi, N.1    Horinaka, S.2    Mita, S.-I.3    Yoshida, K.4    Honda, T.5    Kobayashi, T.6    Hara, K.7    Nishikimi, T.8    Matsuoka, H.9
  • 111
    • 12244266501 scopus 로고    scopus 로고
    • Attenuation of myocardial ischemia/reperfusion injury in mice with myocyte-specific overexpression of endothelial nitric oxide synthase
    • DOI 10.1016/S0008-6363(02)00649-1, PII S0008636302006491
    • Brunner F, Maier R, Andrew P,Wolkart G, Zechner R, Mayer B. Attenuation of myocardial ischemia/reperfusion injury in mice with myocyte-specific overexpression of endothelial nitric oxide synthase. Cardiovasc Res 2003;57:55-62. (Pubitemid 36009436)
    • (2003) Cardiovascular Research , vol.57 , Issue.1 , pp. 55-62
    • Brunner, F.1    Maier, R.2    Andrew, P.3    Wolkart, G.4    Zechner, R.5    Mayer, B.6
  • 112
    • 77950354449 scopus 로고    scopus 로고
    • Cardioselective nitric oxide synthase 3 gene transfer protects against myocardial reperfusion injury
    • Szelid Z, Pokreisz P, Liu X, Vermeersch P, Marsboom G, Gillijns H et al. Cardioselective nitric oxide synthase 3 gene transfer protects against myocardial reperfusion injury. Basic Res Cardiol 2010;105:169-179.
    • (2010) Basic Res Cardiol , vol.105 , pp. 169-179
    • Szelid, Z.1    Pokreisz, P.2    Liu, X.3    Vermeersch, P.4    Marsboom, G.5    Gillijns, H.6


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