Aminoguanidine inhibits mitogen-activated protein kinase and improves cardiac performance and cardiovascular remodeling in failing hearts of salt-sensitive hypertensive rats

Journal of Hypertension

Volumn 20, Issue 12, 2002, Pages 2475-2485

  Kobayashi, Naohiko ^a   Horinaka, Shigeo ^a   Mita, Shin Ichiro ^a   Yoshida, Kohtaro ^a   Honda, Takeaki ^a   Kobayashi, Tsutomu ^a   Hara, Kazuyoshi ^a   Nishikimi, Toshio ^a   Matsuoka, Hiroaki ^a  

^a DOKKYO MEDICAL UNIVERSITY   (Japan)

Author keywords

Gene expression; Heart failure; Nitric oxide; Remodeling; Signal transduction

Indexed keywords

AMINOGUANIDINE; METHYLISOTHIOUREA SULFATE; MITOGEN ACTIVATED PROTEIN KINASE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; SODIUM CHLORIDE; THIOUREA DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CONGESTIVE HEART FAILURE; CONTROLLED STUDY; DRUG ANTAGONISM; GENE EXPRESSION; HEART DISEASE; HEART FAILURE; HEART LEFT VENTRICLE HYPERTROPHY; HEART MUSCLE CONTRACTILITY; HEART MUSCLE FIBROSIS; HEART PERFORMANCE; HEART VENTRICLE REMODELING; HEMODYNAMICS; HIGH SODIUM INTAKE; HYPERTENSION; MALE; NONHUMAN; PRESSURE VOLUME CURVE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

EID: 0036916084     PISSN: 02636352     EISSN: None     Source Type: Journal    
DOI: 10.1097/00004872-200212000-00028     Document Type: Article

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