Cardiomyocyte overexpression of neuronal nitric oxide synthase delays transition toward heart failure in response to pressure overload by preserving calcium cycling

Circulation

Volumn 117, Issue 25, 2008, Pages 3187-3198

  Loyer, Xavier ^a   Gómez, Ana Maria ^a   Milliez, Paul ^a   Fernandez Velasco, Maria ^a   Vangheluwe, Peter ^e   Vinet, Laurent ^b   Charue, Dominique ^a   Vaudin, Emilie ^a   Zhang, Wei ^a   Sainte Marie, Yannis ^a   Robidel, Estelle ^a   Marty, Isabelle ^f   Mayer, Bernd ^c   Jaisser, Frédéric ^a   Mercadier, Jean Jacques ^b   Richard, Sylvain ^a   Shah, Ajay M ^d   Bénitah, Jean Pierre ^a   Samuel, Jane Lise ^a   Heymes, Christophe ^a,g  

^a INSERM   (France)

^b BICHAT HOSPITAL   (France)

^c UNIVERSITY OF GRAZ   (Austria)

^d KING'S COLLEGE LONDON   (United Kingdom)

^e Laboratory of Ca2+ transport ATPases   (Belgium)

^f GRENOBLE INSTITUT DES NEUROSCIENCES   (France)

^g HÔPITAL LARIBOISIÈRE   (France)

Author keywords

Calcium; Heart failure; Hypertrophy; Nitric oxide synthase; Remodeling

Indexed keywords

CALCIUM; NEURONAL NITRIC OXIDE SYNTHASE; PHOSPHOLAMBAN; NOS1 PROTEIN, HUMAN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AORTA CONSTRICTION; ARTICLE; CALCIUM CELL LEVEL; CARDIOVASCULAR PARAMETERS; CONTROLLED STUDY; EXPERIMENTAL MODEL; GENE OVEREXPRESSION; HEART DILATATION; HEART FAILURE; HEART LEFT VENTRICLE; HEART MUSCLE CELL; HEART MUSCLE CONTRACTILITY; HEART VENTRICLE ENDDIASTOLIC PRESSURE; HEART VENTRICLE ENDSYSTOLIC PRESSURE; HEART VENTRICLE REMODELING; HUMAN; HYPERVOLEMIA; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; TRANSGENIC MOUSE; ANIMAL; AORTA; BIOSYNTHESIS; BLOOD PRESSURE; CELL SEPARATION; DISEASE COURSE; DISEASE MODEL; ENZYME ACTIVATION; ENZYMOLOGY; GENETICS; HEART CONTRACTION; HEART LEFT VENTRICLE FUNCTION; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

ANIMALS; AORTA; BLOOD PRESSURE; CALCIUM; CELL SEPARATION; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; ENZYME ACTIVATION; HEART FAILURE; HUMANS; MICE; MICE, TRANSGENIC; MYOCARDIAL CONTRACTION; MYOCYTES, CARDIAC; NITRIC OXIDE SYNTHASE TYPE I; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; VENTRICULAR FUNCTION, LEFT;

EID: 51649088963     PISSN: 00097322     EISSN: 15244539     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.107.741702     Document Type: Article

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