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Volumn 287, Issue 16, 2012, Pages 12634-12644

Structural domains required for Caenorhabditis elegans G protein-coupled receptor kinase 2 (GRK-2) function in Vivo

Author keywords

[No Author keywords available]

Indexed keywords

ALTERNATIVE SUBSTRATES; AMINO ACID SUBSTITUTION; BEHAVIOR CHARACTERISTIC; BIOCHEMICAL DATA; CAENORHABDITIS ELEGANS; CODING SEQUENCES; CRYSTALLOGRAPHIC STUDIES; G PROTEIN COUPLED RECEPTORS; G PROTEIN-COUPLED RECEPTOR KINASE; G PROTEIN-COUPLED RECEPTOR KINASE 2; IN-VITRO; IN-VIVO; KEY REGULATORS; KINASE DOMAINS; MAMMALIAN SYSTEMS; PHOSPHOLIPID BINDING; STRUCTURAL DOMAINS;

EID: 84859768258     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.336818     Document Type: Article
Times cited : (12)

References (66)
  • 1
    • 38449121385 scopus 로고    scopus 로고
    • October 25, The C. elegans Research Community, doi/10.1895/wormbook.1. 123.1
    • Bargmann, C. I. (October 25, 2006) WormBook, The C. elegans Research Community, doi/10.1895/wormbook.1.123.1, www.wormbook.org
    • (2006) WormBook
    • Bargmann, C.I.1
  • 2
    • 0028825369 scopus 로고
    • Divergent seven transmembrane receptors are candidate chemosensory receptors in C. elegans
    • Troemel, E. R., Chou, J. H., Dwyer, N. D., Colbert, H. A., and Bargmann, C. I. (1995) Divergent seven transmembrane receptors are candidate chemosensory receptors in C. elegans. Cell 83, 207-218
    • (1995) Cell , vol.83 , pp. 207-218
    • Troemel, E.R.1    Chou, J.H.2    Dwyer, N.D.3    Colbert, H.A.4    Bargmann, C.I.5
  • 3
    • 1842524194 scopus 로고    scopus 로고
    • Worms taste bitter: ASH neurons, QUI-1, GPA-3 and ODR-3 mediate quinine avoidance in Caenorhabditis elegans
    • DOI 10.1038/sj.emboj.7600107
    • Hilliard, M. A., Bergamasco, C., Arbucci, S., Plasterk, R. H., and Bazzicalupo, P. (2004) Worms taste bitter: ASH neurons, QUI-1, GPA-3 and ODR-3 mediate quinine avoidance in Caenorhabditis elegans. EMBO J. 23, 1101-1111 (Pubitemid 38436874)
    • (2004) EMBO Journal , vol.23 , Issue.5 , pp. 1101-1111
    • Hilliard, M.A.1    Bergamasco, C.2    Arbucci, S.3    Plasterk, R.H.A.4    Bazzicalupo, P.5
  • 6
    • 0029887597 scopus 로고    scopus 로고
    • odr-10 Encodes a seven transmembrane domain olfactory receptor required for responses to the odorant diacetyl
    • DOI 10.1016/S0092-8674(00)81068-5
    • Sengupta, P., Chou, J. H., and Bargmann, C. I. (1996) odr-10 encodes a seven transmembrane domain olfactory receptor required for responses to the odorant diacetyl. Cell 84, 899-909 (Pubitemid 26106859)
    • (1996) Cell , vol.84 , Issue.6 , pp. 899-909
    • Sengupta, P.1    Chou, J.H.2    Bargmann, C.I.3
  • 7
    • 0034464742 scopus 로고    scopus 로고
    • Uncovering molecular mechanisms involved in activation of G protein-coupled receptors
    • Gether, U. (2000) Uncovering molecular mechanisms involved in activation of G protein-coupled receptors. Endocr. Rev. 21, 90-113
    • (2000) Endocr. Rev. , vol.21 , pp. 90-113
    • Gether, U.1
  • 8
    • 0344780741 scopus 로고    scopus 로고
    • G-protein coupled receptor kinases as modulators of G-protein signalling
    • DOI 10.1111/j.1469-7793.1999.0005z.x
    • Bünemann, M., and Hosey, M. M. (1999) G-protein coupled receptor kinases as modulators of G-protein signalling. J. Physiol. 517, 5-23 (Pubitemid 29243467)
    • (1999) Journal of Physiology , vol.517 , Issue.1 , pp. 5-23
    • Bunemann, M.1    Hosey, M.M.2
  • 9
    • 37549016836 scopus 로고    scopus 로고
    • Heterotrimeric G protein activation by G-protein-coupled receptors
    • Oldham, W. M., and Hamm, H. E. (2008) Heterotrimeric G protein activation by G-protein-coupled receptors. Nat. Rev. Mol. Cell Biol. 9, 60-71
    • (2008) Nat. Rev. Mol. Cell Biol. , vol.9 , pp. 60-71
    • Oldham, W.M.1    Hamm, H.E.2
  • 11
    • 0035101820 scopus 로고    scopus 로고
    • Evolving concepts in G protein-coupled receptor endocytosis. The role in receptor desensitization and signaling
    • Ferguson, S. S. (2001) Evolving concepts in G protein-coupled receptor endocytosis. The role in receptor desensitization and signaling. Pharmacol. Rev. 53, 1-24
    • (2001) Pharmacol. Rev. , vol.53 , pp. 1-24
    • Ferguson, S.S.1
  • 12
    • 66149178593 scopus 로고    scopus 로고
    • A surface of the kinase domain critical for the allosteric activation of G protein-coupled receptor kinases
    • Huang, C. C., Yoshino-Koh, K., and Tesmer, J. J. (2009) A surface of the kinase domain critical for the allosteric activation of G protein-coupled receptor kinases. J. Biol. Chem. 284, 17206-17215
    • (2009) J. Biol. Chem. , vol.284 , pp. 17206-17215
    • Huang, C.C.1    Yoshino-Koh, K.2    Tesmer, J.J.3
  • 13
    • 77957778459 scopus 로고    scopus 로고
    • Molecular basis for activation of G protein-coupled receptor kinases
    • Boguth, C. A., Singh, P., Huang, C. C., and Tesmer, J. J. (2010) Molecular basis for activation of G protein-coupled receptor kinases. EMBO J. 29, 3249-3259
    • (2010) EMBO J. , vol.29 , pp. 3249-3259
    • Boguth, C.A.1    Singh, P.2    Huang, C.C.3    Tesmer, J.J.4
  • 20
    • 0032540893 scopus 로고    scopus 로고
    • Control of myocardial contractile function by the level of β-adrenergic receptor kinase 1 in gene-targeted mice
    • DOI 10.1074/jbc.273.29.18180
    • Rockman, H. A., Choi, D. J., Akhter, S. A., Jaber, M., Giros, B., Lefkowitz, R. J., Caron, M. G., and Koch, W. J. (1998) Control of myocardial contractile function by the level of β-adrenergic receptor kinase 1 in gene-targeted mice. J. Biol. Chem. 273, 18180-18184 (Pubitemid 28334737)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.29 , pp. 18180-18184
    • Rockman, H.A.1    Choi, D.-J.2    Akhter, S.A.3    Jaber, M.4    Giros, B.5    Lefkowitz, R.J.6    Caron, M.G.7    Koch, W.J.8
  • 21
    • 0030845179 scopus 로고    scopus 로고
    • G protein-coupled receptor kinase 3 (GRK3) gene disruption leads to loss of odorant receptor desensitization
    • DOI 10.1074/jbc.272.41.25425
    • Peppel, K., Boekhoff, I., McDonald, P., Breer, H., Caron, M. G., and Lefkowitz, R. J. (1997) G protein-coupled receptor kinase 3 (GRK3) gene disruption leads to a loss of odorant receptor desensitization. J. Biol. Chem. 272, 25425-25428 (Pubitemid 27438843)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.41 , pp. 25425-25428
    • Peppel, K.1    Boekhoff, I.2    McDonald, P.3    Breer, H.4    Caron, M.G.5    Lefkowitz, R.J.6
  • 22
    • 0027464698 scopus 로고
    • β-Adrenergic receptor kinase-2 and β-arrestin-2 as mediators of odorant-induced desensitization
    • Dawson, T. M., Arriza, J. L., Jaworsky, D. E., Borisy, F. F., Attramadal, H., Lefkowitz, R. J., and Ronnett, G. V. (1993) β-Adrenergic receptor kinase-2 and β-arrestin-2 as mediators of odorant-induced desensitization. Science 259, 825-829 (Pubitemid 23066314)
    • (1993) Science , vol.259 , Issue.5096 , pp. 825-829
    • Dawson, T.M.1    Arriza, J.L.2    Jaworsky, D.E.3    Borisy, F.F.4    Attramadal, H.5    Lefkowitz, R.J.6    Ronnett, G.V.7
  • 23
    • 0028154118 scopus 로고
    • Olfactory desensitization requires membrane targeting of receptor kinase mediated by βγ-subunits of heterotrimeric G proteins
    • Boekhoff, I., Inglese, J., Schleicher, S., Koch, W. J., Lefkowitz, R. J., and Breer, H. (1994) Olfactory desensitization requires membrane targeting of receptor kinase mediated by βγ-subunits of heterotrimeric G proteins. J. Biol. Chem. 269, 37-40 (Pubitemid 24026616)
    • (1994) Journal of Biological Chemistry , vol.269 , Issue.1 , pp. 37-40
    • Boekhoff, I.1    Inglese, J.2    Schleicher, S.3    Koch, W.J.4    Lefkowitz, R.J.5    Breer, H.6
  • 24
    • 2442475260 scopus 로고    scopus 로고
    • G protein-coupled receptor kinase function is essential for chemosensation in C. elegans
    • DOI 10.1016/S0896-6273(04)00252-1, PII S0896627304002521
    • Fukuto, H. S., Ferkey, D. M., Apicella, A. J., Lans, H., Sharmeen, T., Chen, W., Lefkowitz, R. J., Jansen, G., Schafer, W. R., and Hart, A. C. (2004) G protein-coupled receptor kinase function is essential for chemosensation in C. elegans. Neuron 42, 581-593 (Pubitemid 38639878)
    • (2004) Neuron , vol.42 , Issue.4 , pp. 581-593
    • Fukuto, H.S.1    Ferkey, D.M.2    Apicella, A.J.3    Lans, H.4    Sharmeen, T.5    Chen, W.6    Lefkowitz, R.J.7    Jansen, G.8    Schafer, W.R.9    Hart, A.C.10
  • 26
    • 68049097974 scopus 로고    scopus 로고
    • Role of the amino terminus of G protein-coupled receptor kinase 2 in receptor phosphorylation
    • Pao, C. S., Barker, B. L., and Benovic, J. L. (2009) Role of the amino terminus of G protein-coupled receptor kinase 2 in receptor phosphorylation. Biochemistry 48, 7325-7333
    • (2009) Biochemistry , vol.48 , pp. 7325-7333
    • Pao, C.S.1    Barker, B.L.2    Benovic, J.L.3
  • 28
    • 79952796822 scopus 로고    scopus 로고
    • Activation of G protein-coupled receptor kinase 1 involves interactions between its N-terminal region and its kinase domain
    • Huang, C. C., Orban, T., Jastrzebska, B., Palczewski, K., and Tesmer, J. J. (2011) Activation of G protein-coupled receptor kinase 1 involves interactions between its N-terminal region and its kinase domain. Biochemistry 50, 1940-1949
    • (2011) Biochemistry , vol.50 , pp. 1940-1949
    • Huang, C.C.1    Orban, T.2    Jastrzebska, B.3    Palczewski, K.4    Tesmer, J.J.5
  • 29
    • 0016063911 scopus 로고
    • The genetics of Caenorhabditis elegans
    • Brenner, S. (1974) The genetics of Caenorhabditis elegans. Genetics 77, 71-94
    • (1974) Genetics , vol.77 , pp. 71-94
    • Brenner, S.1
  • 30
    • 0025942107 scopus 로고
    • Efficient gene transfer in C.elegans: Extrachromosomal maintenance and integration of transforming sequences
    • Mello, C. C., Kramer, J. M., Stinchcomb, D., and Ambros, V. (1991) Efficient gene transfer in C. elegans. Extrachromosomal maintenance and integration of transforming sequences. EMBO J. 10, 3959-3970 (Pubitemid 21905425)
    • (1991) EMBO Journal , vol.10 , Issue.12 , pp. 3959-3970
    • Mello, C.C.1    Kramer, J.M.2    Stinchcomb, D.3    Ambros, V.4
  • 31
    • 0032526161 scopus 로고    scopus 로고
    • The GATA-factor elt-2 is essential for formation of the Caenorhabditis elegans intestine
    • DOI 10.1006/dbio.1998.8899
    • Fukushige, T., Hawkins, M. G., and McGhee, J. D. (1998) The GATA-factor elt-2 is essential for formation of the Caenorhabditis elegans intestine. Dev. Biol. 198, 286-302 (Pubitemid 28304445)
    • (1998) Developmental Biology , vol.198 , Issue.2 , pp. 286-302
    • Fukushige, T.1    Hawkins, M.G.2    McGhee, J.D.3
  • 32
    • 77956642884 scopus 로고    scopus 로고
    • Caenorhabditis elegans TRPV channels function in a modality-specific pathway to regulate response to aberrant sensory signaling
    • Ezak, M. J., Hong, E., Chaparro-Garcia, A., and Ferkey, D. M. (2010) Caenorhabditis elegans TRPV channels function in a modality-specific pathway to regulate response to aberrant sensory signaling. Genetics 185, 233-244
    • (2010) Genetics , vol.185 , pp. 233-244
    • Ezak, M.J.1    Hong, E.2    Chaparro-Garcia, A.3    Ferkey, D.M.4
  • 33
    • 0033559456 scopus 로고    scopus 로고
    • Distinct signaling pathways mediate touch and osmosensory responses in a polymodal sensory neuron
    • Hart, A. C., Kass, J., Shapiro, J. E., and Kaplan, J. M. (1999) Distinct signaling pathways mediate touch and osmosensory responses in a polymodal sensory neuron. J. Neurosci. 19, 1952-1958 (Pubitemid 29133373)
    • (1999) Journal of Neuroscience , vol.19 , Issue.6 , pp. 1952-1958
    • Hart, A.C.1    Kass, J.2    Shapiro, J.E.3    Kaplan, J.M.4
  • 34
    • 0037197871 scopus 로고    scopus 로고
    • C. elegans responds to chemical repellents by integrating sensory inputs from the head and the tail
    • DOI 10.1016/S0960-9822(02)00813-8, PII S0960982202008138
    • Hilliard, M. A., Bargmann, C. I., and Bazzicalupo, P. (2002) C. elegans responds to chemical repellents by integrating sensory inputs from the head and the tail. Curr. Biol. 12, 730-734 (Pubitemid 34455426)
    • (2002) Current Biology , vol.12 , Issue.9 , pp. 730-734
    • Hilliard, M.A.1    Bargmann, C.I.2    Bazzicalupo, P.3
  • 35
    • 0004291817 scopus 로고
    • Cold Spring Harbor Laboratory, Cold Spring Harbor, New York
    • Wood, W. B. (1988) The Nematode Caenorhabditis elegans, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York
    • (1988) The Nematode Caenorhabditis Elegans
    • Wood, W.B.1
  • 39
    • 0037044197 scopus 로고    scopus 로고
    • Phosphorylation-independent desensitization of G protein-coupled receptors?
    • Pao, C. S., and Benovic, J. L. (2002) Phosphorylation-independent desensitization of G protein-coupled receptors? Sci. STKE 2002, pe42
    • (2002) Sci. STKE , vol.2002
    • Pao, C.S.1    Benovic, J.L.2
  • 41
    • 0037799206 scopus 로고    scopus 로고
    • Keeping G proteins at bay. A complex between G proteincoupled receptor kinase 2 and Gβγ
    • Lodowski, D. T., Pitcher, J. A., Capel, W. D., Lefkowitz, R. J., and Tesmer, J. J. (2003) Keeping G proteins at bay. A complex between G proteincoupled receptor kinase 2 and Gβγ. Science 300, 1256-1262
    • (2003) Science , vol.300 , pp. 1256-1262
    • Lodowski, D.T.1    Pitcher, J.A.2    Capel, W.D.3    Lefkowitz, R.J.4    Tesmer, J.J.5
  • 42
    • 0031934849 scopus 로고    scopus 로고
    • The Gα protein ODR-3 mediates olfactory and nociceptive function and controls cilium morphogenesis in C. elegans olfactory neurons
    • DOI 10.1016/S0896-6273(00)80434-1
    • Roayaie, K., Crump, J. G., Sagasti, A., and Bargmann, C. I. (1998) The Gα protein ODR-3 mediates olfactory and nociceptive function and controls cilium morphogenesis in C. elegans olfactory neurons. Neuron 20, 55-67 (Pubitemid 28078349)
    • (1998) Neuron , vol.20 , Issue.1 , pp. 55-67
    • Roayaie, K.1    Crump, J.G.2    Sagasti, A.3    Bargmann, C.I.4
  • 44
    • 0032904017 scopus 로고    scopus 로고
    • The complete family of genes encoding G proteins of Caenorhabditis elegans
    • DOI 10.1038/7753
    • Jansen, G., Thijssen, K. L., Werner, P., van der Horst, M., Hazendonk, E., and Plasterk, R. H. (1999) The complete family of genes encoding G proteins of Caenorhabditis elegans. Nat. Genet. 21, 414-419 (Pubitemid 29159580)
    • (1999) Nature Genetics , vol.21 , Issue.4 , pp. 414-419
    • Jansen, G.1    Thijssen, K.L.2    Werner, P.3    Van Der, H.M.4    Hazendonk, E.5    Plasterk, R.H.A.6
  • 45
    • 13244275002 scopus 로고    scopus 로고
    • In vivo imaging of C. elegans ASH neurons: Cellular response and adaptation to chemical repellents
    • DOI 10.1038/sj.emboj.7600493
    • Hilliard, M. A., Apicella, A. J., Kerr, R., Suzuki, H., Bazzicalupo, P., and Schafer, W. R. (2005) In vivo imaging of C. elegans ASH neurons. Cellular response and adaptation to chemical repellents. EMBO J. 24, 63-72 (Pubitemid 40188464)
    • (2005) EMBO Journal , vol.24 , Issue.1 , pp. 63-72
    • Hilliard, M.A.1    Apicella, A.J.2    Kerr, R.3    Suzuki, H.4    Bazzicalupo, P.5    Schafer, W.R.6
  • 46
    • 0028891875 scopus 로고
    • Mutational analysis of the pleckstrin homology domain of the β-adrenergic receptor kinase. Differential effects on Gβγ and phosphatidylinositol 4,5- Bisphosphate binding
    • Touhara, K., Koch, W. J., Hawes, B. E., and Lefkowitz, R. J. (1995) Mutational analysis of the pleckstrin homology domain of the β-adrenergic receptor kinase. Differential effects on Gβγ and phosphatidylinositol 4,5- bisphosphate binding. J. Biol. Chem. 270, 17000-17005
    • (1995) J. Biol. Chem. , vol.270 , pp. 17000-17005
    • Touhara, K.1    Koch, W.J.2    Hawes, B.E.3    Lefkowitz, R.J.4
  • 47
    • 0027481032 scopus 로고
    • The binding site for the βγ subunits of heterotrimeric G proteins on the β-adrenergic receptor kinase
    • Koch, W. J., Inglese, J., Stone, W. C., and Lefkowitz, R. J. (1993) The binding site for the βγ subunits of heterotrimeric G proteins on the β-adrenergic receptor kinase. J. Biol. Chem. 268, 8256-8260 (Pubitemid 23120415)
    • (1993) Journal of Biological Chemistry , vol.268 , Issue.11 , pp. 8256-8260
    • Koch, W.J.1    Inglese, J.2    Stone, W.C.3    Lefkowitz, R.J.4
  • 49
    • 0025302932 scopus 로고
    • Characterization of a G-protein β-subunit gene from the nematode Caenorhabditis elegans
    • DOI 10.1016/S0022-2836(05)80118-4
    • van der Voorn, L., Gebbink, M., Plasterk, R. H., and Ploegh, H. L. (1990) Characterization of a G protein β-subunit gene from the nematode Caenorhabditis elegans. J. Mol. Biol. 213, 17-26 (Pubitemid 20171094)
    • (1990) Journal of Molecular Biology , vol.213 , Issue.1 , pp. 17-26
    • Van Der, V.L.1    Gebbink, M.2    Plasterk, R.H.A.3    Ploegh, H.L.4
  • 50
    • 0030598875 scopus 로고    scopus 로고
    • G proteins are required for spatial orientation of early cell cleavages in C. elegans embryos
    • DOI 10.1016/S0092-8674(00)80135-X
    • Zwaal, R. R., Ahringer, J., van Luenen, H. G., Rushforth, A., Anderson, P., and Plasterk, R. H. (1996)Gproteins are required for spatial orientation of early cell cleavages in C. elegans embryos. Cell 86, 619-629 (Pubitemid 26299493)
    • (1996) Cell , vol.86 , Issue.4 , pp. 619-629
    • Zwaal, R.R.1    Ahringer, J.2    Van Luenen, H.G.A.M.3    Rushforth, A.4    Anderson, P.5    Plasterk, R.H.A.6
  • 51
    • 34247563776 scopus 로고    scopus 로고
    • Efficient and cell specific knock-down of gene function in targeted C. elegans neurons
    • DOI 10.1016/j.gene.2007.03.002, PII S0378111907001187
    • Esposito, G., Di Schiavi, E., Bergamasco, C., and Bazzicalupo, P. (2007) Efficient and cell specific knock-down of gene function in targeted C. elegans neurons. Gene 395, 170-176 (Pubitemid 46670643)
    • (2007) Gene , vol.395 , Issue.1-2 , pp. 170-176
    • Esposito, G.1    Di, S.E.2    Bergamasco, C.3    Bazzicalupo, P.4
  • 52
    • 38449120056 scopus 로고    scopus 로고
    • October 13, The C. elegans Research Community, doi/10.1895/wormbook.1.75. 1
    • Bastiani, C., and Mendel, J. (October 13, 2006) WormBook, The C. elegans Research Community, doi/10.1895/wormbook.1.75.1, www.wormbook.org
    • (2006) WormBook
    • Bastiani, C.1    Mendel, J.2
  • 55
    • 0035012431 scopus 로고    scopus 로고
    • qα signaling network through interactions with the regulator of G-protein signaling proteins EGL-10 and EAT-16
    • qα signaling network through interactions with the regulator of G-protein signaling proteins EGL-10 and EAT-16. Genetics 158, 221-235
    • (2001) Genetics , vol.158 , pp. 221-235
    • Van Der Linden, A.M.1    Simmer, F.2    Cuppen, E.3    Plasterk, R.H.4
  • 56
    • 0036499967 scopus 로고    scopus 로고
    • The G-protein γ subunit gpc-1 of the nematode C.elegans is involved in taste adaptation
    • DOI 10.1093/emboj/21.5.986
    • Jansen, G., Weinkove, D., and Plasterk, R. H. (2002) The G protein γ subunit gpc-1 of the nematode C. elegans is involved in taste adaptation. EMBO J. 21, 986-994 (Pubitemid 34206171)
    • (2002) EMBO Journal , vol.21 , Issue.5 , pp. 986-994
    • Jansen, G.1    Weinkove, D.2    Plasterk, R.H.A.3
  • 57
    • 67650244426 scopus 로고    scopus 로고
    • GPC-1, a G protein γ-subunit, regulates olfactory adaptation in Caenorhabditis elegans
    • Yamada, K., Hirotsu, T., Matsuki, M., Kunitomo, H., and Iino, Y. (2009) GPC-1, a G protein γ-subunit, regulates olfactory adaptation in Caenorhabditis elegans. Genetics 181, 1347-1357
    • (2009) Genetics , vol.181 , pp. 1347-1357
    • Yamada, K.1    Hirotsu, T.2    Matsuki, M.3    Kunitomo, H.4    Iino, Y.5
  • 58
    • 0034745355 scopus 로고    scopus 로고
    • Distinct roles for Gα and Gβγ in regulating spindle position and orientation in Caenorhabditis elegans embryos
    • DOI 10.1038/35060092
    • Gotta, M., and Ahringer, J. (2001) Distinct roles for Gα and Gβγ in regulating spindle position and orientation in Caenorhabditis elegans embryos. Nat. Cell Biol. 3, 297-300 (Pubitemid 32201325)
    • (2001) Nature Cell Biology , vol.3 , Issue.3 , pp. 297-300
    • Gotta, M.1    Ahringer, J.2
  • 59
    • 0033486229 scopus 로고    scopus 로고
    • Chemosensory signaling in C. elegans
    • Troemel, E. R. (1999) Chemosensory signaling in C. elegans. Bioessays 21, 1011-1020
    • (1999) Bioessays , vol.21 , pp. 1011-1020
    • Troemel, E.R.1
  • 60
    • 0033119614 scopus 로고    scopus 로고
    • Chemosensation: Molecular mechanisms in worms and mammals
    • DOI 10.1016/S0168-9525(99)01695-9, PII S0168952599016959
    • Prasad, B. C., and Reed, R. R. (1999) Chemosensation. Molecular mechanisms in worms and mammals. Trends Genet. 15, 150-153 (Pubitemid 29155437)
    • (1999) Trends in Genetics , vol.15 , Issue.4 , pp. 150-153
    • Prasad, B.C.1    Reed, R.R.2
  • 62
    • 0036324072 scopus 로고    scopus 로고
    • Expression and activity of G protein-coupled receptor kinases in differentiated thyroid carcinoma
    • DOI 10.1210/jc.87.7.3279
    • Métayé, T., Menet, E., Guilhot, J., and Kraimps, J. L. (2002) Expression and activity of G protein-coupled receptor kinases in differentiated thyroid carcinoma. J. Clin. Endocrinol. Metab. 87, 3279-3286 (Pubitemid 34816377)
    • (2002) Journal of Clinical Endocrinology and Metabolism , vol.87 , Issue.7 , pp. 3279-3286
    • Metaye, T.1    Menet, E.2    Guilhot, J.3    Kraimps, J.-L.4
  • 63
    • 0031038950 scopus 로고    scopus 로고
    • Defects in the rhodopsin kinase gene in the Oguchi form of stationary night blindness
    • DOI 10.1038/ng0297-175
    • Yamamoto, S., Sippel, K. C., Berson, E. L., and Dryja, T. P. (1997) Defects in the rhodopsin kinase gene in the Oguchi form of stationary night blindness. Nat. Genet. 15, 175-178 (Pubitemid 27061637)
    • (1997) Nature Genetics , vol.15 , Issue.2 , pp. 175-178
    • Yamamoto, S.1    Sippel, K.C.2    Berson, E.L.3    Dryja, T.P.4
  • 64
    • 33846249884 scopus 로고    scopus 로고
    • Mechanisms of regulation and function of G-protein-coupled receptor kinases
    • Yang, W., and Xia, S. H. (2006) Mechanisms of regulation and function of G-protein-coupled receptor kinases. World J. Gastroenterol. 12, 7753-7757 (Pubitemid 46099941)
    • (2006) World Journal of Gastroenterology , vol.12 , Issue.48 , pp. 7753-7757
    • Yang, W.1    Xia, S.-H.2
  • 65
    • 0035696235 scopus 로고    scopus 로고
    • Protein kinases modulate the cellular adaptations associated with opioid tolerance and dependence
    • Liu, J. G., and Anand, K. J. (2001) Protein kinases modulate the cellular adaptations associated with opioid tolerance and dependence. Brain Res. Brain Res. Rev. 38, 1-19
    • (2001) Brain Res. Brain Res. Rev. , vol.38 , pp. 1-19
    • Liu, J.G.1    Anand, K.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.