Development of a yeast bioassay to characterize G protein-coupled receptor kinases: Identification of an NH2-terminal region essential for receptor phosphorylation

Journal of Biological Chemistry

Volumn 278, Issue 48, 2003, Pages 47466-47476

  Noble, Beth ^a   Kallal, Lorena A ^a,c   Pausch, Mark H ^b   Benovic, Jeffrey L ^a,d  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b Neuroscience Discovery Research   (United States)

^c GLAXOSMITHKLINE   (United States)

^d THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BIOASSAY; CATALYSIS; PHOSPHOLIPIDS; PROTEINS; PURIFICATION; YEAST;

OPTIMAL RECEPTOR PHOSPHORYLATION;

BIOCHEMISTRY;

AMINO ACID; G PROTEIN COUPLED RECEPTOR; G PROTEIN COUPLED RECEPTOR KINASE; G PROTEIN COUPLED RECEPTOR KINASE 2; G PROTEIN COUPLED RECEPTOR KINASE 5; PHOSPHOLIPID; SOMATOSTATIN RECEPTOR; SOMATOSTATIN RECEPTOR 2; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; AUTOPHOSPHORYLATION; BIOASSAY; DELETION MUTANT; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME PURIFICATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LIPID INTERACTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION;

ANIMALS; BETA-ADRENERGIC RECEPTOR KINASE; BIOLOGICAL ASSAY; CATALYSIS; CELL DIVISION; CELL LINE; COS CELLS; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DOSE-RESPONSE RELATIONSHIP, DRUG; GENETIC VECTORS; HUMANS; INSECTS; KINETICS; LIPIDS; MUTAGENESIS; MUTATION; PEPTIDES; PHOSPHOLIPIDS; PHOSPHORYLATION; PLASMIDS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTEIN-SERINE-THREONINE KINASES; RECEPTORS, ADRENERGIC, BETA-2; SACCHAROMYCES CEREVISIAE; TIME FACTORS;

ANIMALIA;

EID: 0346850855     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M308257200     Document Type: Article

References (44)

1. Krupnick, J. G., and Benovie, J. L. (1998) Annu. Rev. Pharmacol. Toxicol. 38, 289-319
2. Ferguson, S. S. G. (2001) Pharmacol. Rev. 53, 1-24
3. Perry, S. J., and Lefkowitz, R. J. (2002) Trends Cell Biol. 12, 130-138
4. Stoffel, R. H., Pitcher, J. A., and Lefkowitz, R. J. (1997) J. Membr. Biol. 157, 1-8
5. Pitcher, J. A., Freedman, N. J., and Lefkowitz, R. J. (1998) Annu. Rev. Biochem. 67, 653-692
6. Penn, R. B., Pronin, A. N., and Benovic, J. L. (2000) Trends Cardiovasc. Med. 10, 81-89
7. Palczewski, K., Buczylko, J., Lebioda, L., Crabb, J. W., and Polans, A. S. (1993) J. Biol. Chem. 268, 6004-6013
8. Yu, Q. M., Cheng, Z. J., Gan, X. Q., Bao, G. B., Li, L., and Pei, G. (1999) J. Neurochem. 73, 1222-1227
9. Pitcher, J. A., Fredericks, Z. L., Stone, C. W., Premont, R. T., Stoffel, R. H., Koch, W. J., and Lefkowitz, R. J. (1996) J. Biol. Chem. 271, 24907-24913
10. Kurjan, J. (1992) Annu. Rev. Biochem. 61, 1097-1129
11. Wittenberg, C., and Reed, S. I. (1996) Curr. Opin. Cell Biol. 8, 223-230
12. Banuett, F. (1998) Microbiol. Mol. Biol. Rev. 62, 249-274
13. Price, L. A., Kajkowski, E. M., Hadcock, J. R., Ozenberger, B. A., and Pausch, M. P. (1995) Mol. Cell. Biol. 15, 6188-6195
14. Kang, Y. S., Kane, J., Kurjan, J., Stadel, J. M., and Tipper, D. J. (1990) Mol. Cell. Biol. 10, 2582-2590
15. Dietzel, C., and Kurjan, J. (1987) Mol. Cell. Biol. 7, 4169-4177
16. Sikorski, R. S., and Hieter, P. (1989) Genetics 122, 19-27
17. McCammon, M. T., Veenhuis, M., Trapp, S. B., and Goodman, J. M. (1990) Bacteriology 172, 5816-5827
18. Sherman, F. (1991) Methods Enzymol. 194, 3-21
19. St. Jean, A., Woods, R. A., and Schiestl, R. H. (1991) Nucleic Acids Res. 20, 1425
20. Stevenson, B. J., Rhodes, N., Errede, B., and Sprague, G. F. (1992) Genes Dev. 6, 1293-1304
21. Rothstein, R. (1991) Methods Enzymol. 194, 281-301
22. Kunapuli, P., and Benovic, J. L. (1993) Proc. Natl. Acad. Sci. U.S.A. 90, 5588-5592
23. Pronin, A. N., Carman, C. V., and Benovic, J. L. (1998) J. Biol. Chem. 273, 31510-31518
24. Pronin, A. N., and Benovic, J. L. (1997) J. Biol. Chem. 272, 3806-3812
25. Kobilka, B. K. (1995) Anal. Biochem. 231, 269-271
26. Kunapuli, P., Onorato, J. J., Hosey, M. M., and Benovic, J. L. (1994) J. Biol. Chem. 269, 1099-1105
27. Dowell, S. J., and Brown, A. J., (2002) Recept. Channels 8, 343-352
28. Mayor, F., Benovic, J. L., Caron, M. G., and Lefkowitz, R. J. (1987) J. Biol. Chem. 262, 6468-6471
29. Hipkin, W. R., Friedman, J., Clark, R. B., Eppler, M. C., and Schonbrunn, A. (1997) J. Biol. Chem. 272, 13869-13876
30. Hipkin, R. W., Wang, Y., and Schonbrunn, A. (2000) J. Biol. Chem. 275, 5591-5599
31. Siderovski, D. P., Hessel, A., Chung, S., Mak, T. W., and Tyers, M. (1996) Curr. Biol. 6, 211-212
32. Carman, C. V., Parent, J. L., Day, P. W., Pronin, A. N., Sternweis, P. M., Wedegaertner, P. B., Gilman, A. G., Benovic, J. L., and Kozasa, T. (1999) J. Biol. Chem. 274, 34483-34492
33. Usui, H., Nishiyama, M., Moroi, K., Shbasaki, T., Zhou, J., Ishida, J., Fukamizu, A., Haga, T., Sekita, S., and Kimura, S. (2000) Int. J. Mol. Med. 4, 335-340
34. Sallese, M., Mariggio, S., D'Urbano, E., Iacovelli, L., and De Blasi, A. (2000) Mol. Pharmacol. 57, 826-831
35. Carman, C. V., Lisanti, M. P., and Benovic, J. L. (1999) J. Biol. Chem. 274, 8858-8864
36. Chuang, T. T., Paolucci, L., and De Blasi, A. (1996) J. Biol. Chem. 271, 28691-28696
37. Pronin, A. N., Satpaev, D. K., Slepak, V. Z., and Benovic, J. L. (1997) J. Biol. Chem. 272, 18273-18280
38. Levay, K., Satpaev, D. K., Pronin, A. N., Benovic, J. L., and Slepak, V. Z. (1998) Biochemistry 37, 13650-13659
39. Sallese, M., Iacovelli, L., Cumashi, A., Capobianco, L., Cuomo, L., and De Blasi, A. (2000) Biochim. Biophys. Acta 1498, 112-121
40. Lodowski, D. T., Pitcher, J. A., Capel, W. D., Lefkowitz, R. J., and Tesmer, J. J. (2003) Science 300, 1256-1262
41. Rockman, H. A., Choi, D. J., Rahman, N. U., Akhter, S. A., Lefkowitz, R. J., and Koch, W. J. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 9954-9959
42. Carman, C. V., Som, T., Kim, C. M., and Benovic, J. L. (1998) J. Biol. Chem. 273, 20308-20316
43. Kunapuli, P., Gurevich, V. V., and Benovic, J. L. (1994) J. Biol. Chem. 269, 10209-10212
44. Iaccarino, G., Lefkowitz, R. J., and Koch, W. J. (1999) Proc. Assoc. Am. Physicians 111, 399-405