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Volumn 2012, Issue , 2012, Pages

Application of physiologically based pharmacokinetic models in chemical risk assessment

Author keywords

[No Author keywords available]

Indexed keywords

3,3',5' TRIIODOTHYRONINE; BENZENE; CARBON TETRACHLORIDE; CHLORPYRIFOS; DICHLOROMETHANE; PARATHION; TETRACHLOROETHYLENE; THYROTROPIN; THYROXINE; TRICHLOROETHYLENE; VINYL CHLORIDE;

EID: 84859739254     PISSN: 16878191     EISSN: 16878205     Source Type: Journal    
DOI: 10.1155/2012/904603     Document Type: Review
Times cited : (31)

References (82)
  • 1
    • 79957909845 scopus 로고    scopus 로고
    • Evaluating pharmacokinetic and pharmacodynamic interactions with computational models in supporting cumulative risk assessment
    • Tan Y.-M., Clewell H., Campbell J., Andersen M., Evaluating pharmacokinetic and pharmacodynamic interactions with computational models in supporting cumulative risk assessment International Journal of Environmental Research and Public Health 2011 8 5 1613 1630
    • (2011) International Journal of Environmental Research and Public Health , vol.8 , Issue.5 , pp. 1613-1630
    • Tan, Y.-M.1    Clewell, H.2    Campbell, J.3    Andersen, M.4
  • 2
    • 79951774366 scopus 로고    scopus 로고
    • Physiologically-based pharmacokinetic modeling for absorption, transport, metabolism and excretion
    • Pang K. S., Durk M. R., Physiologically-based pharmacokinetic modeling for absorption, transport, metabolism and excretion Journal of Pharmacokinetics and Pharmacodynamics 2010 37 6 591 615
    • (2010) Journal of Pharmacokinetics and Pharmacodynamics , vol.37 , Issue.6 , pp. 591-615
    • Pang, K.S.1    Durk, M.R.2
  • 3
    • 33947133630 scopus 로고    scopus 로고
    • PBPK models in risk assessment-A focus on chloroprene
    • DeWoskin R. S., PBPK models in risk assessment-A focus on chloroprene Chemico-Biological Interactions 2007 166 13 352 359
    • (2007) Chemico-Biological Interactions , vol.166 , Issue.13 , pp. 352-359
    • Dewoskin, R.S.1
  • 6
    • 26444453754 scopus 로고    scopus 로고
    • Improving the development and use of biologically based dose response models (BBDR) in risk assessment
    • DeWoskin R. S., Barone S., Clewell H. J., Setzer R. W., Improving the development and use of biologically based dose response models (BBDR) in risk assessment Human and Ecological Risk Assessment 2001 7 5 1091 1120
    • (2001) Human and Ecological Risk Assessment , vol.7 , Issue.5 , pp. 1091-1120
    • Dewoskin, R.S.1    Barone, S.2    Clewell, H.J.3    Setzer, R.W.4
  • 8
    • 11344264355 scopus 로고    scopus 로고
    • Framework for evaluation of physiologically-based pharmacokinetic models for use in safety or risk assessment
    • DOI 10.1111/j.0272-4332.2004.00561.x
    • Clark L. H., Setzer R. W., Barton H. A., Framework for evaluation of physiologically-based pharmacokinetic models for use in safety or risk assessment Risk Analysis 2004 24 6 1697 1717 (Pubitemid 40076089)
    • (2004) Risk Analysis , vol.24 , Issue.6 , pp. 1697-1717
    • Clark, L.H.1    Setzer, R.W.2    Barton, H.A.3
  • 9
    • 0029086832 scopus 로고
    • Development of physiologically based pharmacokinetic and physiologically based pharmacodynamic models for applications in toxicology and risk assessment
    • Andersen M. E., Development of physiologically based pharmacokinetic and physiologically based pharmacodynamic models for applications in toxicology and risk assessment Toxicology Letters 1995 79 13 35 44
    • (1995) Toxicology Letters , vol.79 , Issue.13 , pp. 35-44
    • Andersen, M.E.1
  • 14
    • 79959922934 scopus 로고    scopus 로고
    • Assessing the toxic effects of ethylene glycol ethers using Quantitative Structure Toxicity Relationship models
    • Ruiz P., Mumtaz M., Gombar V., Assessing the toxic effects of ethylene glycol ethers using Quantitative Structure Toxicity Relationship models Toxicology and Applied Pharmacology 2011 254 2 198 205
    • (2011) Toxicology and Applied Pharmacology , vol.254 , Issue.2 , pp. 198-205
    • Ruiz, P.1    Mumtaz, M.2    Gombar, V.3
  • 16
    • 0031587525 scopus 로고    scopus 로고
    • Investigation of the potential impact of benchmark dose and pharmacokinetic modeling in noncancer risk assessment
    • Clewell H. J., Gentry P. R., Gearhart J. M., Investigation of the potential impact of benchmark dose and pharmacokinetic modeling in noncancer risk assessment Journal of Toxicology and Environmental HealthPart A 1997 52 6 475 515
    • (1997) Journal of Toxicology and Environmental HealthPart A , vol.52 , Issue.6 , pp. 475-515
    • Clewell, H.J.1    Gentry, P.R.2    Gearhart, J.M.3
  • 17
    • 0000936119 scopus 로고    scopus 로고
    • Minimal risk levels for priority substances and guidance for derivation
    • Agency for Toxic Substances and Disease Registry (ATSDR)
    • Agency for Toxic Substances and Disease Registry (ATSDR), Minimal risk levels for priority substances and guidance for derivation Federal Register 1996 61 125 33511 33520
    • (1996) Federal Register , vol.61 , Issue.125 , pp. 33511-33520
  • 18
    • 0004011126 scopus 로고    scopus 로고
    • Agency for Toxic Substances and Disease Registry (ATSDR) Atlanta, Ga, USA ATSDR
    • Agency for Toxic Substances and Disease Registry (ATSDR), Toxicological Profile for Mercury Compounds, Update 1997 Atlanta, Ga, USA ATSDR
    • (1997) Toxicological Profile for Mercury Compounds, Update
  • 19
    • 84859755045 scopus 로고
    • Agency for Toxic Substances and Disease Registry (ATSDR) Atlanta, Ga, USA ATSDR
    • Agency for Toxic Substances and Disease Registry (ATSDR), Toxicological Profile for Mercury Compounds, Update 1995 Atlanta, Ga, USA ATSDR
    • (1995) Toxicological Profile for Mercury Compounds, Update
  • 22
    • 0027000809 scopus 로고
    • A weight-of-evidence approach for assessing interactions in chemical mixtures
    • Mumtaz M. M., Durkin P. R., A weight-of-evidence approach for assessing interactions in chemical mixtures Toxicology and Industrial Health 1992 8 6 377 406 (Pubitemid 23128807)
    • (1992) Toxicology and Industrial Health , vol.8 , Issue.6 , pp. 377-406
    • Mumtaz, M.M.1    Durkin, P.R.2
  • 24
    • 0004259368 scopus 로고    scopus 로고
    • Agency for Toxic Substances and Disease Registry (ATSDR) Atlanta, GA, USA U.S. Department of Health and Human Services, Agency for Toxic Substances and Disease Registry
    • Agency for Toxic Substances and Disease Registry (ATSDR), Toxicological Profile of Chlorpyrifos 1997 Atlanta, GA, USA U.S. Department of Health and Human Services, Agency for Toxic Substances and Disease Registry
    • (1997) Toxicological Profile of Chlorpyrifos
  • 25
    • 1542286120 scopus 로고    scopus 로고
    • Application of physiologically-based pharmacokinetic modeling to investigate the toxicological interaction between chlorpyrifos and parathion in the rat
    • DOI 10.1016/j.etap.2003.10.002, PII S1382668903001017
    • El-Masri H. A., Mumtaz M. M., Yushak M. L., Application of physiologically-based pharmacokinetic modeling to investigate the toxicological interaction between chlorpyrifos and parathion in the rat Environmental Toxicology and Pharmacology 2004 16 1-2 57 71 (Pubitemid 38314895)
    • (2004) Environmental Toxicology and Pharmacology , vol.16 , Issue.1-2 , pp. 57-71
    • El-Masri, H.A.1    Mumtaz, M.M.2    Yushak, M.L.3
  • 27
    • 84859761421 scopus 로고    scopus 로고
    • BBPK model of the hypothalamic-pituitary-thyroid axis in the adult rat
    • ARTICLE 394
    • McLanahan E. D., Andersen M. E., Mumtaz M., Fisher J. W., BBPK model of the hypothalamic-pituitary-thyroid axis in the adult rat The Toxicologist 2007 96 1, article 394
    • (2007) The Toxicologist , vol.96 , Issue.1
    • McLanahan, E.D.1    Andersen, M.E.2    Mumtaz, M.3    Fisher, J.W.4
  • 28
    • 40949107694 scopus 로고    scopus 로고
    • A biologically based dose-response model for dietary iodide and the hypothalamic-pituitary-thyroid axis in the adult Rat: Evaluation of iodide deficiency
    • DOI 10.1093/toxsci/kfm312
    • Mclanahan E. D., Andersen M. E., Fisher J. W., A biologically based dose-response model for dietary iodide and the hypothalamic-pituitary-thyroid axis in the adult Rat: evaluation of iodide deficiency Toxicological Sciences 2008 102 2 241 253 (Pubitemid 351404896)
    • (2008) Toxicological Sciences , vol.102 , Issue.2 , pp. 241-253
    • Mclanahan, E.D.1    Andersen, M.E.2    Fisher, J.W.3
  • 29
    • 15444364182 scopus 로고    scopus 로고
    • Evaluation of potential toxicity from co-exposure to three CNS depressants (toluene, ethylbenzene, and xylene) under resting and working conditions using PBPK modeling
    • Dennison J. E., Bigelow P. L., Mumtaz M. M., Andersen M. E., Dobrev I. D., Yang R. S. H., Evaluation of potential toxicity from co-exposure to three CNS depressants (toluene, ethylbenzene, and xylene) under resting and working conditions using PBPK modeling Journal of Occupational and Environmental Hygiene 2005 2 3 127 135
    • (2005) Journal of Occupational and Environmental Hygiene , vol.2 , Issue.3 , pp. 127-135
    • Dennison, J.E.1    Bigelow, P.L.2    Mumtaz, M.M.3    Andersen, M.E.4    Dobrev, I.D.5    Yang, R.S.H.6
  • 30
    • 14844323234 scopus 로고    scopus 로고
    • Occupational Safety and Health Administration (OSHA) Code of Federal Regulations, Title 29, Part 1910.1000, 2004
    • Occupational Safety and Health Administration (OSHA), Air Contaminants. Code of Federal Regulations, Title 29, Part 1910.1000, 2004
    • Air Contaminants
  • 31
    • 0003920182 scopus 로고    scopus 로고
    • Agency for Toxic Substances and Disease Registry (ATSDR) Atlanta, Ga, USA U.S. Department of Health and Human Services, Agency for Toxic Substances and Disease Registry
    • Agency for Toxic Substances and Disease Registry (ATSDR), Toxicological Profile of Polychlorinated Biphenyls 2000 Atlanta, Ga, USA U.S. Department of Health and Human Services, Agency for Toxic Substances and Disease Registry
    • (2000) Toxicological Profile of Polychlorinated Biphenyls
  • 32
    • 0017571707 scopus 로고
    • A preliminary pharmacokinetic model for several chlorinated biphenyls in the rat
    • Lutz R. J., Dedrick R. L., Matthews H. B., A preliminary pharmacokinetic model for several chlorinated biphenyls in the rat Drug Metabolism and Disposition 1977 5 4 386 396 (Pubitemid 8327318)
    • (1977) Drug Metabolism and Disposition , vol.5 , Issue.4 , pp. 386-396
    • Lutz, R.J.1    Dedrick, R.L.2    Matthews, H.B.3
  • 33
    • 0031172737 scopus 로고    scopus 로고
    • Using structural information to create physiologically based pharmacokinetic models for all polychlorinated biphenyls I. Tissue:Blood partition coefficients
    • DOI 10.1006/taap.1997.8139
    • Parham F. M., Kohn M. C., Matthews H. B., DeRosa C., Portier C. J., Using structural information to create physiologically based pharmacokinetic models for all polychlorinated biphenyls I. Tissue:Blood partition coefficients Toxicology and Applied Pharmacology 1997 144 2 340 347 (Pubitemid 27268356)
    • (1997) Toxicology and Applied Pharmacology , vol.144 , Issue.2 , pp. 340-347
    • Parham, F.M.1    Kohn, M.C.2    Matthews, H.B.3    DeRosa, C.4    Portier, C.J.5
  • 34
    • 0031754099 scopus 로고    scopus 로고
    • Using structural information to create physiologically based pharmacokinetic models for all polychlorinated biphenyls. II: Rates of metabolism
    • DOI 10.1006/taap.1998.8441
    • Parham F. M., Portier C. J., Using structural information to create physiologically based pharmacokinetic models for all polychlorinated biphenyls. II: rates of metabolism Toxicology and Applied Pharmacology 1998 151 1 110 116 (Pubitemid 28406657)
    • (1998) Toxicology and Applied Pharmacology , vol.151 , Issue.1 , pp. 110-116
    • Parham, F.M.1    Portier, C.J.2
  • 42
    • 0032192157 scopus 로고    scopus 로고
    • A human physiologically based pharmacokinetic model for trichloroethylene and its metabolites, trichloroacetic acid and free trichloroethanol
    • DOI 10.1006/taap.1998.8486
    • Fisher J. W., Mahle D., Abbas R., A human physiologically based pharmacokinetic model for trichloroethylene and its metabolites, trichloroacetic acid and free trichloroethanol Toxicology and Applied Pharmacology 1998 152 2 339 359 (Pubitemid 28492276)
    • (1998) Toxicology and Applied Pharmacology , vol.152 , Issue.2 , pp. 339-359
    • Fisher, J.W.1    Mahle, D.2    Abbas, R.3
  • 43
    • 0035796897 scopus 로고    scopus 로고
    • Comparison of cancer risk estimates for vinyl chloride using animal and human data with a PBPK model
    • DOI 10.1016/S0048-9697(01)00730-6, PII S0048969701007306
    • Clewell H. J., Gentry P. R., Gearhart J. M., Allen B. C., Andersen M. E., Comparison of cancer risk estimates for vinyl chloride using animal and human data with a PBPK model Science of the Total Environment 2001 274 13 37 66 (Pubitemid 32591381)
    • (2001) Science of the Total Environment , vol.274 , Issue.1-3 , pp. 37-66
    • Clewell, H.J.1    Gentry, P.R.2    Gearhart, J.M.3    Allen, B.C.4    Andersen, M.E.5
  • 44
    • 0343090508 scopus 로고    scopus 로고
    • Development of a physiologically based pharmacokinetic model of trichloroethylene and its metabolites for use in risk assessment
    • Clewell H. J., Gentry P. R., Covington T. R., Gearhart J. M., Development of a physiologically based pharmacokinetic model of trichloroethylene and its metabolites for use in risk assessment Environmental Health Perspectives 2000 108 2 283 305 (Pubitemid 30420987)
    • (2000) Environmental Health Perspectives , vol.108 , Issue.SUPPL. 2 , pp. 283-305
    • Clewell III, H.J.1    Gentry, P.R.2    Covington, T.R.3    Gearhart, J.M.4
  • 45
    • 21844454441 scopus 로고    scopus 로고
    • Evaluation of physiologically based pharmacokinetic models in risk assessment: An example with perchloroethylene
    • DOI 10.1080/10408440590931994
    • Clewell H. J., Gentry P. R., Kester J. E., Andersen M. E., Evaluation of physiologically based pharmacokinetic models in risk assessment: an example with perchloroethylene Critical Reviews in Toxicology 2005 35 5 413 433 (Pubitemid 40962110)
    • (2005) Critical Reviews in Toxicology , vol.35 , Issue.5 , pp. 413-433
    • Clewell, H.J.1    Gentry, P.R.2    Kester, J.E.3    Andersen, M.E.4
  • 47
    • 0015157964 scopus 로고
    • Tissue weights and rates of blood flow in man for the prediction of anesthetic uptake and distribution
    • Cowles A. L., Borgstedt H. H., Gillies A. J., Tissue weights and rates of blood flow in man for the prediction of anesthetic uptake and distribution Anesthesiology 1971 35 5 523 526
    • (1971) Anesthesiology , vol.35 , Issue.5 , pp. 523-526
    • Cowles, A.L.1    Borgstedt, H.H.2    Gillies, A.J.3
  • 48
    • 0033958043 scopus 로고    scopus 로고
    • Physiologically based pharmacokinetic modeling of the temperature- dependent dermal absorption of chloroform by humans following bath water exposures
    • Corley R. A., Gordon S. M., Wallace L. A., Physiologically based pharmacokinetic modeling of the temperature- dependent dermal absorption of chloroform by humans following bath water exposures Toxicological Sciences 2000 53 1 13 23 (Pubitemid 30043598)
    • (2000) Toxicological Sciences , vol.53 , Issue.1 , pp. 13-23
    • Corley, R.A.1    Gordon, S.M.2    Wallace, L.A.3
  • 49
    • 81255185289 scopus 로고    scopus 로고
    • Agency for Toxic Substances and Disease Registry (ATSDR) Atlanta, Ga, USA U.S. Department of Health and Human Services, Public Health Service
    • Agency for Toxic Substances and Disease Registry (ATSDR), Toxicological Profile for Perchloroethylene 1997 Atlanta, Ga, USA U.S. Department of Health and Human Services, Public Health Service
    • (1997) Toxicological Profile for Perchloroethylene
  • 50
    • 0004037664 scopus 로고    scopus 로고
    • Agency for Toxic Substances and Disease Registry (ATSDR) Atlanta, Ga, USA U.S. Department of Health and Human Services, Public Health Service
    • Agency for Toxic Substances and Disease Registry (ATSDR), Toxicological Profile for Trichloroethylene 1997 Atlanta, Ga, USA U.S. Department of Health and Human Services, Public Health Service
    • (1997) Toxicological Profile for Trichloroethylene
  • 51
    • 81255159005 scopus 로고    scopus 로고
    • Agency for Toxic Substances and Disease Registry (ATSDR) Atlanta, Ga, USA U.S. Department of Health and Human Services, Public Health Service
    • Agency for Toxic Substances and Disease Registry (ATSDR), Toxicological Profile for Dichloromethane 2000 Atlanta, Ga, USA U.S. Department of Health and Human Services, Public Health Service
    • (2000) Toxicological Profile for Dichloromethane
  • 52
    • 0003615543 scopus 로고    scopus 로고
    • Agency for Toxic Substances and Disease Registry (ATSDR) Atlanta, Ga, USA U.S. Department of Health and Human Services, Public Health Service
    • Agency for Toxic Substances and Disease Registry (ATSDR), Toxicological Profile for Carbon Tetrachloride 2005 Atlanta, Ga, USA U.S. Department of Health and Human Services, Public Health Service
    • (2005) Toxicological Profile for Carbon Tetrachloride
  • 53
    • 34247631141 scopus 로고    scopus 로고
    • Agency for Toxic Substances and Disease Registry (ATSDR) Atlanta, Ga, USA U.S. Department of Health and Human Services, Public Health Service
    • Agency for Toxic Substances and Disease Registry (ATSDR), Toxicological Profile for Vinyl Chloride 2006 Atlanta, Ga, USA U.S. Department of Health and Human Services, Public Health Service
    • (2006) Toxicological Profile for Vinyl Chloride
  • 54
    • 0003815886 scopus 로고    scopus 로고
    • Agency for Toxic Substances and Disease Registry (ATSDR) Atlanta, Ga, USA U.S. Department of Health and Human Services, Public Health Service
    • Agency for Toxic Substances and Disease Registry (ATSDR), Toxicological Profile for Benzene 2007 Atlanta, Ga, USA U.S. Department of Health and Human Services, Public Health Service
    • (2007) Toxicological Profile for Benzene
  • 55
    • 77954173954 scopus 로고    scopus 로고
    • Centers for Disease Control and Prevention (CDC) Atlanta, Ga, USA Division of Laboratory Sciences, National Center for Environmental Health
    • Centers for Disease Control and Prevention (CDC), Fourth National Report on Human Exposure to Environmental Chemicals 2009 Atlanta, Ga, USA Division of Laboratory Sciences, National Center for Environmental Health
    • (2009) Fourth National Report on Human Exposure to Environmental Chemicals
  • 56
    • 41049110206 scopus 로고    scopus 로고
    • Development of a human physiologically based pharmacokinetic (PBPK) model for inorganic arsenic and its mono- and di-methylated metabolites
    • DOI 10.1007/s10928-007-9075-z
    • El-Masri H. A., Kenyon E. M., Development of a human physiologically based pharmacokinetic (PBPK) model for inorganic arsenic and its mono- and di-methylated metabolites Journal of Pharmacokinetics and Pharmacodynamics 2008 35 1 31 68 (Pubitemid 351420762)
    • (2008) Journal of Pharmacokinetics and Pharmacodynamics , vol.35 , Issue.1 , pp. 31-68
    • El-Masri, H.A.1    Kenyon, E.M.2
  • 57
    • 0035865561 scopus 로고    scopus 로고
    • A toxicokinetic model for predicting the tissue distribution and elimination of organic and inorganic mercury following exposure to methyl mercury in animals and humans. I. Development and validation of the model using experimental data in rats
    • DOI 10.1006/taap.2000.9112
    • Carrier G., Brunet R. C., Caza M., Bouchard M., A toxicokinetic model for predicting the tissue distribution and elimination of organic and inorganic mercury following exposure to methyl mercury in animals and humans. I. Development and validation of the model using experimental data in rats Toxicology and Applied Pharmacology 2001 171 1 38 49 (Pubitemid 32182293)
    • (2001) Toxicology and Applied Pharmacology , vol.171 , Issue.1 , pp. 38-49
    • Carrier, G.1    Brunet, R.C.2    Caza, M.3    Bouchard, M.4
  • 58
    • 0035865477 scopus 로고    scopus 로고
    • A toxicokinetic model for predicting the tissue distribution and elimination of organic and inorganic mercury following exposure to methyl mercury in animals and humans. II. Application and validation of the model in humans
    • DOI 10.1006/taap.2000.9113
    • Carrier G., Bouchard M., Brunet R. C., Caza M., A toxicokinetic model for predicting the tissue distribution and elimination of organic and inorganic mercury following exposure to methyl mercury in animals and humans. II. Application and validation of the model in humans Toxicology and Applied Pharmacology 2001 171 1 50 60 (Pubitemid 32182294)
    • (2001) Toxicology and Applied Pharmacology , vol.171 , Issue.1 , pp. 50-60
    • Carrier, G.1    Bouchard, M.2    Brunet, R.C.3    Caza, M.4
  • 60
    • 0242721534 scopus 로고    scopus 로고
    • Pharmacokinetics/pharmacodynamics (PK/PD) modeling of risks of kidney toxicity from exposure to cadmium: Estimates of dietary risks in the U.S. population
    • DOI 10.1080/15287390390227589
    • Diamond G. L., Thayer W. C., Choudhury H., Pharmacokinetics/ pharmacodynamics (PK/PD) modeling of risks of kidney toxicity from exposure to cadmium: estimates of dietary risks in the U.S. population Journal of Toxicology and Environmental HealthPart A 2003 66 22 2141 2164 (Pubitemid 37421735)
    • (2003) Journal of Toxicology and Environmental Health - Part A , vol.66 , Issue.22 , pp. 2141-2164
    • Diamond, G.L.1    Thayer, W.C.2    Choudhury, H.3
  • 61
    • 0018095992 scopus 로고
    • A kinetic model of cadmium metabolism in the human being
    • Kjellstrm T., Nordberg G. F., A kinetic model of cadmium metabolism in the human being Environmental Research 1978 16 13 248 269 (Pubitemid 8369435)
    • (1978) Environmental Research , vol.16 , Issue.1-3 , pp. 248-269
    • Kjellstrom, T.1    Nordberg, G.F.2
  • 62
    • 36248961660 scopus 로고    scopus 로고
    • Reverse dosimetry: Interpreting trihalomethanes biomonitoring data using physiologically based pharmacokinetic modeling
    • DOI 10.1038/sj.jes.7500540, PII 7500540
    • Tan Y.-M., Liao K. H., Clewell H. J., Reverse dosimetry: interpreting trihalomethanes biomonitoring data using physiologically based pharmacokinetic modeling Journal of Exposure Science and Environmental Epidemiology 2007 17 7 591 603 (Pubitemid 350126884)
    • (2007) Journal of Exposure Science and Environmental Epidemiology , vol.17 , Issue.7 , pp. 591-603
    • Tan, Y.-M.1    Liao, K.H.2    Clewell, H.J.3
  • 63
    • 33751084895 scopus 로고    scopus 로고
    • Biomonitoring equivalents: A screening approach for interpreting biomonitoring results from a public health risk perspective
    • DOI 10.1016/j.yrtph.2006.08.004, PII S0273230006001449
    • Hays S. M., Becker R. A., Leung H. W., Aylward L. L., Pyatt D. W., Biomonitoring equivalents: a screening approach for interpreting biomonitoring results from a public health risk perspective Regulatory Toxicology and Pharmacology 2007 47 1 96 109 (Pubitemid 44765127)
    • (2007) Regulatory Toxicology and Pharmacology , vol.47 , Issue.1 , pp. 96-109
    • Hays, S.M.1    Becker, R.A.2    Leung, H.W.3    Aylward, L.L.4    Pyatt, D.W.5
  • 64
    • 33746825024 scopus 로고    scopus 로고
    • Use of a physiologically based pharmacokinetic model to identify exposures consistent with human biomonitoring data for chloroform
    • DOI 10.1080/15287390600631367, PII R2V2567620P4206V
    • Tan Y. M., Liao K., Conolly R., Blount B., Mason A., Clewell H., Use of a physiologically based pharmacokinetic model to identify exposures consistent with human biomonitoring data for chloroform Journal of Toxicology and Environmental HealthPart A 2006 69 18 1727 1756 (Pubitemid 44174510)
    • (2006) Journal of Toxicology and Environmental Health - Part A: Current Issues , vol.69 , Issue.18 , pp. 1727-1756
    • Tan, Y.-M.1    Liao, K.2    Conolly, R.3    Blount, B.4    Mason, A.5    Clewell, H.6
  • 65
    • 36849035487 scopus 로고    scopus 로고
    • Development of a screening approach to interpret human biomonitoring data on volatile organic compounds: Reverse dosimetry on biomonitoring data for trichloroethylene
    • DOI 10.1111/j.1539-6924.2007.00964.x
    • Liao K. H., Tan Y. M., Clewell H. J., Development of a screening approach to interpret human biomonitoring data on volatile organic compounds: reverse dosimetry on biomonitoring data for trichloroethylene Risk Analysis 2007 27 5 1223 1236 (Pubitemid 350222035)
    • (2007) Risk Analysis , vol.27 , Issue.5 , pp. 1223-1236
    • Liao, K.H.1    Tan, Y.-M.2    Clewell III, H.J.3
  • 67
    • 51249103031 scopus 로고    scopus 로고
    • Computational toxicology of chloroform: Reverse dosimetry using Bayesian inference, Markov chain Monte Carlo simulation, and human biomonitoring data
    • Lyons M. A., Yang R. S. H., Mayeno A. N., Reisfeld B., Computational toxicology of chloroform: reverse dosimetry using Bayesian inference, Markov chain Monte Carlo simulation, and human biomonitoring data Environmental Health Perspectives 2008 116 8 1040 1046
    • (2008) Environmental Health Perspectives , vol.116 , Issue.8 , pp. 1040-1046
    • Lyons, M.A.1    Yang, R.S.H.2    Mayeno, A.N.3    Reisfeld, B.4
  • 68
    • 0027943431 scopus 로고
    • Reconstruction of short-term multi-route exposure to volatile organic compounds using physiologically based pharmacokinetic models
    • Georgopoulos P. G., Roy A., Gallo M. A., Reconstruction of short-term multi-route exposure to volatile organic compounds using physiologically based pharmacokinetic models Journal of Exposure Analysis and Environmental Epidemiology 1994 4 3 309 328 (Pubitemid 24335163)
    • (1994) Journal of Exposure Analysis and Environmental Epidemiology , vol.4 , Issue.3 , pp. 309-328
    • Georgopoulos, P.G.1    Roy, A.2    Gallo, M.A.3
  • 69
    • 0032987027 scopus 로고    scopus 로고
    • Exposure estimates to disinfection by-products of chlorinated drinking water
    • Weisel C. P., Kim H., Haltmeier P., Klotz J. B., Exposure estimates to disinfection by-products of chlorinated drinking water Environmental Health Perspectives 1999 107 2 103 110 (Pubitemid 29137720)
    • (1999) Environmental Health Perspectives , vol.107 , Issue.2 , pp. 103-110
    • Weisel, C.P.1    Kim, H.2    Haltmeier, P.3    Klotz, J.B.4
  • 70
  • 71
    • 77955920291 scopus 로고    scopus 로고
    • Chemical-specific screening criteria for interpretation of biomonitoring data for volatile organic compounds (VOCs)application of steady-state PBPK model solutions
    • Aylward L. L., Kirman C. R., Blount B. C., Hays S. M., Chemical-specific screening criteria for interpretation of biomonitoring data for volatile organic compounds (VOCs)application of steady-state PBPK model solutions Regulatory Toxicology and Pharmacology 2010 58 1 33 44
    • (2010) Regulatory Toxicology and Pharmacology , vol.58 , Issue.1 , pp. 33-44
    • Aylward, L.L.1    Kirman, C.R.2    Blount, B.C.3    Hays, S.M.4
  • 73
    • 34248328303 scopus 로고    scopus 로고
    • Integration of in vitro neurotoxicity data with biokinetic modelling for the estimation of in vivo neurotoxicity
    • DOI 10.1177/0960327106072994
    • Forsby A., Blaauboer B., Integration of in vitro neurotoxicity data with biokinetic modelling for the estimation of in vivo neurotoxicity Human and Experimental Toxicology 2007 26 4 333 338 (Pubitemid 46733356)
    • (2007) Human and Experimental Toxicology , vol.26 , Issue.4 , pp. 333-338
    • Forsby, A.1    Blaauboer, B.2
  • 74
    • 0037452421 scopus 로고    scopus 로고
    • The integration of data on physico-chemical properties, in vitro-derived toxicity data and physiologically based kinetic and dynamic as modelling a tool in hazard and risk assessment. A commentary
    • DOI 10.1016/S0378-4274(02)00367-3, PII S0378427402003673
    • Blaauboer B. J., The integration of data on physico-chemical properties, in vitro -derived toxicity data and physiologically based kinetic and dynamic as modelling a tool in hazard and risk assessment. A commentary Toxicology Letters 2003 138 1-2 161 171 (Pubitemid 36139973)
    • (2003) Toxicology Letters , vol.138 , Issue.1-2 , pp. 161-171
    • Blaauboer, B.J.1
  • 75
    • 37349017573 scopus 로고    scopus 로고
    • Physiologically based approaches towards the prediction of pharmacokinetics: In vitro-in vivo extrapolation
    • DOI 10.1517/17425255.3.6.865
    • De Buck S. S., Mackie C. E., Physiologically based approaches towards the prediction of pharmacokinetics: in vitro-in vivo extrapolation Expert Opinion on Drug Metabolism and Toxicology 2007 3 6 865 878 (Pubitemid 350285340)
    • (2007) Expert Opinion on Drug Metabolism and Toxicology , vol.3 , Issue.6 , pp. 865-878
    • De Buck, S.S.1    Mackie, C.E.2
  • 77
    • 78549237487 scopus 로고    scopus 로고
    • The use of in vitro toxicity data and physiologically based kinetic modeling to predict dose-response curves for in vivo developmental toxicity of glycol ethers in rat and man
    • Louisse J., de Jong E., van de Sandt J. J. M., Blaauboer B. J., Woutersen R. A., Piersma A. H., Rietjens I. M. C. M., Verwei M., The use of in vitro toxicity data and physiologically based kinetic modeling to predict dose-response curves for in vivo developmental toxicity of glycol ethers in rat and man Toxicological Sciences 2010 118 2 470 484
    • (2010) Toxicological Sciences , vol.118 , Issue.2 , pp. 470-484
    • Louisse, J.1    De Jong, E.2    Van De Sandt, J.J.M.3    Blaauboer, B.J.4    Woutersen, R.A.5    Piersma, A.H.6    Rietjens, I.M.C.M.7    Verwei, M.8
  • 78
    • 2942683492 scopus 로고    scopus 로고
    • Reconstructing population exposures from dose biomarkers: Inhalation of trichloroethylene (TCE) as a case study
    • DOI 10.1038/sj.jea.7500314
    • Sohn M. D., McKone T. E., Blancato J. N., Reconstructing population exposures from dose biomarkers: inhalation of trichloroethylene (TCE) as a case study Journal of Exposure Analysis and Environmental Epidemiology 2004 14 3 204 213 (Pubitemid 38765943)
    • (2004) Journal of Exposure Analysis and Environmental Epidemiology , vol.14 , Issue.3 , pp. 204-213
    • Sohn, M.D.1    McKone, T.E.2    Blancato, J.N.3
  • 79
    • 0027622753 scopus 로고
    • Linking a PBPK model for chloroform with measured breath concentrations in showers: Implications for dermal exposure models
    • McKone T. E., Linking a PBPK model for chloroform with measured breath concentrations in showers: implications for dermal exposure models Journal of Exposure Analysis and Environmental Epidemiology 1993 3 3 339 365
    • (1993) Journal of Exposure Analysis and Environmental Epidemiology , vol.3 , Issue.3 , pp. 339-365
    • McKone, T.E.1
  • 80
    • 0024230343 scopus 로고
    • Linking indoor air and pharmacokinetic models to assess tetrachloroethylene risk
    • DOI 10.1111/j.1539-6924.1988.tb01191.x
    • Bogen K. T., McKone T. E., Linking indoor air and pharmacokinetic models to assess tetrachloroethylene risk Risk Analysis 1988 8 4 509 520 (Pubitemid 19037084)
    • (1988) Risk Analysis , vol.8 , Issue.4 , pp. 509-520
    • Bogen, K.T.1    McKone, T.E.2


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