-
1
-
-
26444573778
-
A physiologically based toxicokinetic model of inhalation exposure to xylenes in Caucasian men
-
Adams J.C., Dills R.L., Morgan M.S., Kalman D.A., Pierce C.H. A physiologically based toxicokinetic model of inhalation exposure to xylenes in Caucasian men. Regul. Toxicol. Pharmacol. 2005, 43:203-214.
-
(2005)
Regul. Toxicol. Pharmacol.
, vol.43
, pp. 203-214
-
-
Adams, J.C.1
Dills, R.L.2
Morgan, M.S.3
Kalman, D.A.4
Pierce, C.H.5
-
4
-
-
0004206867
-
-
Dutch National Institute of Public Health and the Environment, Bilthoven, Netherlands
-
Baars A.J., Theelen R.M.C., Janssen P.J.C.M., Hesse J.M., van Apeldoorn M.E., Meijerink M.C.M., Verdam L., Zeilmaker M.J. Re-Evaluation of Human-Toxicological Maximum Permissible Risk Levels. RIVM Report 711701 025 2001, Dutch National Institute of Public Health and the Environment, Bilthoven, Netherlands.
-
(2001)
Re-Evaluation of Human-Toxicological Maximum Permissible Risk Levels. RIVM Report 711701 025
-
-
Baars, A.J.1
Theelen, R.M.C.2
Janssen, P.J.C.M.3
Hesse, J.M.4
van Apeldoorn, M.E.5
Meijerink, M.C.M.6
Verdam, L.7
Zeilmaker, M.J.8
-
5
-
-
0032051783
-
A pharmacokinetic study of occupational and environmental benzene exposure with regard to gender
-
Brown E.A., Shelley M.L., Fisher J.W. A pharmacokinetic study of occupational and environmental benzene exposure with regard to gender. Risk Anal. 1998, 18:205-213.
-
(1998)
Risk Anal.
, vol.18
, pp. 205-213
-
-
Brown, E.A.1
Shelley, M.L.2
Fisher, J.W.3
-
6
-
-
0030806348
-
Physiological parameter values for physiologically based pharmacokinetic models
-
Brown R.P., Delp M.D., Lindstedt S.L., Rhomberg L.R., Beliles R.P. Physiological parameter values for physiologically based pharmacokinetic models. Toxicol. Ind. Health 1997, 13:407-484.
-
(1997)
Toxicol. Ind. Health
, vol.13
, pp. 407-484
-
-
Brown, R.P.1
Delp, M.D.2
Lindstedt, S.L.3
Rhomberg, L.R.4
Beliles, R.P.5
-
7
-
-
27744543374
-
-
Department of Health and Human Services, Atlanta, GA, Centers for Disease Control, Prevention (CDC)
-
Centers for Disease Control, Prevention (CDC) Third National Report on Human Exposure to Environmental Chemicals 2005, Department of Health and Human Services, Atlanta, GA.
-
(2005)
Third National Report on Human Exposure to Environmental Chemicals
-
-
-
8
-
-
33745340354
-
Steady-state solutions to PBPK models and their applications to risk assessment I: route-to-route extrapolation of volatile chemicals
-
Chiu W.A., White P. Steady-state solutions to PBPK models and their applications to risk assessment I: route-to-route extrapolation of volatile chemicals. Risk Anal. 2006, 26:769-780.
-
(2006)
Risk Anal.
, vol.26
, pp. 769-780
-
-
Chiu, W.A.1
White, P.2
-
9
-
-
33751083612
-
The use of Markov chain Monte Carlo uncertainty analysis to support a Public Health Goal for perchloroethylene
-
Covington T.R., Robinan Gentry P., Van Landingham C.B., Andersen M.E., Kester J.E., Clewell H.J. The use of Markov chain Monte Carlo uncertainty analysis to support a Public Health Goal for perchloroethylene. Regul. Toxicol. Pharmacol. 2007, 47:1-18.
-
(2007)
Regul. Toxicol. Pharmacol.
, vol.47
, pp. 1-18
-
-
Covington, T.R.1
Robinan Gentry, P.2
Van Landingham, C.B.3
Andersen, M.E.4
Kester, J.E.5
Clewell, H.J.6
-
10
-
-
37849189752
-
Biological monitoring of tetrahydrofuran: contribution of a physiologically based pharmacokinetic model
-
Droz P.O., Berode M., Jang J.Y. Biological monitoring of tetrahydrofuran: contribution of a physiologically based pharmacokinetic model. Am. Ind. Hyg. Assoc. J. 1999, 60:243-248.
-
(1999)
Am. Ind. Hyg. Assoc. J.
, vol.60
, pp. 243-248
-
-
Droz, P.O.1
Berode, M.2
Jang, J.Y.3
-
11
-
-
0024412384
-
Determining kinetic constants of chlorinated ethane metabolism in the rat from rates of exhalation
-
Gargas M.L., Andersen M.E. Determining kinetic constants of chlorinated ethane metabolism in the rat from rates of exhalation. Toxicol. Appl. Pharmacol. 1989, 99:344-353.
-
(1989)
Toxicol. Appl. Pharmacol.
, vol.99
, pp. 344-353
-
-
Gargas, M.L.1
Andersen, M.E.2
-
12
-
-
0024524118
-
Partition coefficients of low-molecular-weight volatile chemicals in various liquids and tissues
-
Gargas M.L., Burgess R.J., Voisard D.E., Cason G.H., Andersen M.E. Partition coefficients of low-molecular-weight volatile chemicals in various liquids and tissues. Toxicol. Appl. Pharmacol. 1989, 98:87-99.
-
(1989)
Toxicol. Appl. Pharmacol.
, vol.98
, pp. 87-99
-
-
Gargas, M.L.1
Burgess, R.J.2
Voisard, D.E.3
Cason, G.H.4
Andersen, M.E.5
-
13
-
-
0001656675
-
Gas uptake inhalation techniques and rates of metabolism of chloromethanes, chloroethanes, and chloroethylenes in the rat
-
Gargas M.L., Clewell H.J., Andersen M.E. Gas uptake inhalation techniques and rates of metabolism of chloromethanes, chloroethanes, and chloroethylenes in the rat. Inhal. Toxicol. 1990, 2:295-319.
-
(1990)
Inhal. Toxicol.
, vol.2
, pp. 295-319
-
-
Gargas, M.L.1
Clewell, H.J.2
Andersen, M.E.3
-
14
-
-
33750301144
-
Development of physiologically based toxicokinetic models for improving the human indoor exposure assessment to water contaminants: trichloroethylene and trihalomethanes
-
Haddad S., Tardif G.C., Tardif R. Development of physiologically based toxicokinetic models for improving the human indoor exposure assessment to water contaminants: trichloroethylene and trihalomethanes. J. Toxicol. Environ. Health A 2006, 69:2095-2136.
-
(2006)
J. Toxicol. Environ. Health A
, vol.69
, pp. 2095-2136
-
-
Haddad, S.1
Tardif, G.C.2
Tardif, R.3
-
15
-
-
47549112161
-
Guidelines for the derivation of Biomonitoring Equivalents: report from the Biomonitoring Equivalents Expert Workshop
-
Hays S.M., Aylward L.L., LaKind J.S., Bartels M.J., Barton H.A., Boogaard P.J., Brunk C., DiZio S., Dourson M., Goldstein D.A., Lipscomb J., Kilpatrick M.E., Krewski D., Krishnan K., Nordberg M., Okino M., Tan Y.M., Viau C., Yager J.W. Guidelines for the derivation of Biomonitoring Equivalents: report from the Biomonitoring Equivalents Expert Workshop. Regul. Toxicol. Pharmacol. 2008, 51:S4-S15.
-
(2008)
Regul. Toxicol. Pharmacol.
, vol.51
-
-
Hays, S.M.1
Aylward, L.L.2
LaKind, J.S.3
Bartels, M.J.4
Barton, H.A.5
Boogaard, P.J.6
Brunk, C.7
DiZio, S.8
Dourson, M.9
Goldstein, D.A.10
Lipscomb, J.11
Kilpatrick, M.E.12
Krewski, D.13
Krishnan, K.14
Nordberg, M.15
Okino, M.16
Tan, Y.M.17
Viau, C.18
Yager, J.W.19
-
16
-
-
33751084895
-
Biomonitoring equivalents: a screening approach for interpreting biomonitoring results from a public health risk perspective
-
Hays S.M., Becker R.A., Leung H.W., Aylward L.L., Pyatt D.W. Biomonitoring equivalents: a screening approach for interpreting biomonitoring results from a public health risk perspective. Regul. Toxicol. Pharmacol. 2007, 47:96-109.
-
(2007)
Regul. Toxicol. Pharmacol.
, vol.47
, pp. 96-109
-
-
Hays, S.M.1
Becker, R.A.2
Leung, H.W.3
Aylward, L.L.4
Pyatt, D.W.5
-
17
-
-
0031214663
-
A physiologically based pharmacokinetic (PB-PK) model for 1, 2-dichlorobenzene linked to two possible parameters of toxicity
-
Hissink A.M., Van Ommen B., Kruse J., Van Bladeren P.J. A physiologically based pharmacokinetic (PB-PK) model for 1, 2-dichlorobenzene linked to two possible parameters of toxicity. Toxicol. Appl. Pharmacol. 1997, 145:301-310.
-
(1997)
Toxicol. Appl. Pharmacol.
, vol.145
, pp. 301-310
-
-
Hissink, A.M.1
Van Ommen, B.2
Kruse, J.3
Van Bladeren, P.J.4
-
18
-
-
0033923457
-
A physiologically-based pharmacokinetic (PB-PK) model for ethylene dibromide: relevance of extrahepatic metabolism
-
Hissink A.M., Wormhoudt L.W., Sherratt P.J., Hayes J.D., Commandeur J.N., Vermeulen N.P., van Bladeren P.J. A physiologically-based pharmacokinetic (PB-PK) model for ethylene dibromide: relevance of extrahepatic metabolism. Food Chem. Toxicol. 2000, 38:707-716.
-
(2000)
Food Chem. Toxicol.
, vol.38
, pp. 707-716
-
-
Hissink, A.M.1
Wormhoudt, L.W.2
Sherratt, P.J.3
Hayes, J.D.4
Commandeur, J.N.5
Vermeulen, N.P.6
van Bladeren, P.J.7
-
19
-
-
0030246901
-
Prediction of furan pharmacokinetics from hepatocyte studies: comparison of bioactivation and hepatic dosimetry in rats, mice, and humans
-
Kedderis G.L., Held S.D. Prediction of furan pharmacokinetics from hepatocyte studies: comparison of bioactivation and hepatic dosimetry in rats, mice, and humans. Toxicol. Appl. Pharmacol. 1996, 140:124-130.
-
(1996)
Toxicol. Appl. Pharmacol.
, vol.140
, pp. 124-130
-
-
Kedderis, G.L.1
Held, S.D.2
-
20
-
-
26444572796
-
The threshold of toxicological concern concept in risk assessment
-
Kroes R., Kleiner J., Renwick A. The threshold of toxicological concern concept in risk assessment. Toxicol. Sci. 2005, 86:226-230.
-
(2005)
Toxicol. Sci.
, vol.86
, pp. 226-230
-
-
Kroes, R.1
Kleiner, J.2
Renwick, A.3
-
21
-
-
47549090116
-
Guidelines for the communication of Biomonitoring Equivalents: report from the Biomonitoring Equivalents Expert Workshop
-
LaKind J.S., Aylward L.L., Brunk C., DiZio S., Dourson M., Goldstein D.A., Kilpatrick M.E., Krewski D., Bartels M.J., Barton H.A., Boogaard P.J., Lipscomb J., Krishnan K., Nordberg M., Okino M., Tan Y.M., Viau C., Yager J.W., Hays S.M. Guidelines for the communication of Biomonitoring Equivalents: report from the Biomonitoring Equivalents Expert Workshop. Regul. Toxicol. Pharmacol. 2008, 51:S16-S26.
-
(2008)
Regul. Toxicol. Pharmacol.
, vol.51
-
-
LaKind, J.S.1
Aylward, L.L.2
Brunk, C.3
DiZio, S.4
Dourson, M.5
Goldstein, D.A.6
Kilpatrick, M.E.7
Krewski, D.8
Bartels, M.J.9
Barton, H.A.10
Boogaard, P.J.11
Lipscomb, J.12
Krishnan, K.13
Nordberg, M.14
Okino, M.15
Tan, Y.M.16
Viau, C.17
Yager, J.W.18
Hays, S.M.19
-
22
-
-
36849035487
-
Development of a screening approach to interpret human biomonitoring data on volatile organic compounds: reverse dosimetry on biomonitoring data for trichloroethylene
-
Liao K.H., Tan Y.M., Clewell H.J. Development of a screening approach to interpret human biomonitoring data on volatile organic compounds: reverse dosimetry on biomonitoring data for trichloroethylene. Risk Anal. 2007, 27:1223-1236.
-
(2007)
Risk Anal.
, vol.27
, pp. 1223-1236
-
-
Liao, K.H.1
Tan, Y.M.2
Clewell, H.J.3
-
23
-
-
0034894807
-
A physiologically based pharmacokinetic model for methyl tert-butyl ether in humans: implementing sensitivity and variability analyses
-
Licata A.C., Dekant W., Smith C.E., Borghoff S.J. A physiologically based pharmacokinetic model for methyl tert-butyl ether in humans: implementing sensitivity and variability analyses. Toxicol. Sci. 2001, 62:191-204.
-
(2001)
Toxicol. Sci.
, vol.62
, pp. 191-204
-
-
Licata, A.C.1
Dekant, W.2
Smith, C.E.3
Borghoff, S.J.4
-
24
-
-
42649085362
-
In vitro measurements of metabolism for application in pharmacokinetic modeling
-
Lipscomb J.S., Poet T.S. In vitro measurements of metabolism for application in pharmacokinetic modeling. Pharmacol. Ther. 2008, 118:82-103.
-
(2008)
Pharmacol. Ther.
, vol.118
, pp. 82-103
-
-
Lipscomb, J.S.1
Poet, T.S.2
-
25
-
-
0037184820
-
Guidelines for application of chemical-specific adjustment factors in dose/concentration-response assessment
-
Meek M.E., Renwick A., Ohanian E., Dourson M., Lake B., Naumann B.D., Vu V. Guidelines for application of chemical-specific adjustment factors in dose/concentration-response assessment. Toxicology 2002, 181-182:115-120.
-
(2002)
Toxicology
, pp. 115-120
-
-
Meek, M.E.1
Renwick, A.2
Ohanian, E.3
Dourson, M.4
Lake, B.5
Naumann, B.D.6
Vu, V.7
-
26
-
-
34249103335
-
Estimation of interindividual pharmacokinetic variability factor for inhaled volatile organic chemicals using a probability-bounds approach
-
Nong A., Krishnan K. Estimation of interindividual pharmacokinetic variability factor for inhaled volatile organic chemicals using a probability-bounds approach. Regul. Toxicol. Pharmacol. 2007, 48:93-101.
-
(2007)
Regul. Toxicol. Pharmacol.
, vol.48
, pp. 93-101
-
-
Nong, A.1
Krishnan, K.2
-
27
-
-
1542678695
-
Physiologically based algebraic expressions for predicting steady-state toxicokinetics of inhaled vapors
-
Pelekis M., Krewski D., Krishnan K. Physiologically based algebraic expressions for predicting steady-state toxicokinetics of inhaled vapors. Toxicol. Methods 1997, 7:205-225.
-
(1997)
Toxicol. Methods
, vol.7
, pp. 205-225
-
-
Pelekis, M.1
Krewski, D.2
Krishnan, K.3
-
28
-
-
4544298810
-
Development of a physiologically based pharmacokinetic model for decane, a constituent of jet propellent-8
-
Perleberg U.R., Keys D.A., Fisher J.W. Development of a physiologically based pharmacokinetic model for decane, a constituent of jet propellent-8. Inhal. Toxicol. 2004, 16:771-783.
-
(2004)
Inhal. Toxicol.
, vol.16
, pp. 771-783
-
-
Perleberg, U.R.1
Keys, D.A.2
Fisher, J.W.3
-
29
-
-
0142010672
-
Modeling interindividual variation in physiological factors used in PBPK models of humans
-
Price P.S., Conolly R.B., Chaisson C.F., Gross E.A., Young J.S., Mathis E.T., Tedder D.R. Modeling interindividual variation in physiological factors used in PBPK models of humans. Crit. Rev. Toxicol. 2003, 33:469-503.
-
(2003)
Crit. Rev. Toxicol.
, vol.33
, pp. 469-503
-
-
Price, P.S.1
Conolly, R.B.2
Chaisson, C.F.3
Gross, E.A.4
Young, J.S.5
Mathis, E.T.6
Tedder, D.R.7
-
30
-
-
55949134304
-
Simulation of repeated dose kinetics of methyl isobutyl ketone in humans from experimental single-dose inhalation exposure
-
Saghir S.A., Rick D.L. Simulation of repeated dose kinetics of methyl isobutyl ketone in humans from experimental single-dose inhalation exposure. Regul. Toxicol. Pharmacol. 2008, 52:180-188.
-
(2008)
Regul. Toxicol. Pharmacol.
, vol.52
, pp. 180-188
-
-
Saghir, S.A.1
Rick, D.L.2
-
31
-
-
17044407575
-
Rat tissue and blood partition coefficients for n-alkanes (C8 to C12)
-
Smith A.Q., Campbell J.L., Keys D.A., Fisher J.W. Rat tissue and blood partition coefficients for n-alkanes (C8 to C12). Int. J. Toxicol. 2005, 24:35-41.
-
(2005)
Int. J. Toxicol.
, vol.24
, pp. 35-41
-
-
Smith, A.Q.1
Campbell, J.L.2
Keys, D.A.3
Fisher, J.W.4
-
32
-
-
0037253723
-
Physiologically based pharmacokinetic model parameter estimation and sensitivity and variability analyses for acrylonitrile disposition in humans
-
Sweeney L.M., Gargas M.L., Strother D.E., Kedderis G.L. Physiologically based pharmacokinetic model parameter estimation and sensitivity and variability analyses for acrylonitrile disposition in humans. Toxicol. Sci. 2003, 71:27-40.
-
(2003)
Toxicol. Sci.
, vol.71
, pp. 27-40
-
-
Sweeney, L.M.1
Gargas, M.L.2
Strother, D.E.3
Kedderis, G.L.4
-
33
-
-
0029016437
-
Physiologically-based pharmacokinetic modeling of a mixture of toluene and xylene in humans
-
Tardif R., Lapare S., Charest-Tardif G., Brodeur J., Krishnan K. Physiologically-based pharmacokinetic modeling of a mixture of toluene and xylene in humans. Risk Anal. 1995, 15:335-342.
-
(1995)
Risk Anal.
, vol.15
, pp. 335-342
-
-
Tardif, R.1
Lapare, S.2
Charest-Tardif, G.3
Brodeur, J.4
Krishnan, K.5
-
34
-
-
0030069951
-
Variability in biological exposure indices using physiologically based pharmacokinetic modeling and Monte Carlo simulation
-
Thomas R.S., Bigelow P.L., Keefe T.J., Yang R.S. Variability in biological exposure indices using physiologically based pharmacokinetic modeling and Monte Carlo simulation. Am. Ind. Hyg. Assoc. J. 1996, 57:23-32.
-
(1996)
Am. Ind. Hyg. Assoc. J.
, vol.57
, pp. 23-32
-
-
Thomas, R.S.1
Bigelow, P.L.2
Keefe, T.J.3
Yang, R.S.4
-
35
-
-
77955921924
-
-
USEPA, Approaches for the Application of Physiologically Based Pharmacokinetic (PBPK) Models and Supporting Data in Risk Assessment (External Review Draft 2005). Appendix 3: partition coefficients and metabolic rate constants for PBPK modeling of environmental chemicals. US Environmental Protection Agency, Washington, DC, EPA/600/R-05/043A, 2005. Available from: .
-
USEPA, 2005. Approaches for the Application of Physiologically Based Pharmacokinetic (PBPK) Models and Supporting Data in Risk Assessment (External Review Draft 2005). Appendix 3: partition coefficients and metabolic rate constants for PBPK modeling of environmental chemicals. US Environmental Protection Agency, Washington, DC, EPA/600/R-05/043A, 2005. Available from: http://cfpub.epa.gov/ncea/CFM/recordisplay.cfm?deid=135427.
-
(2005)
-
-
-
36
-
-
77955925073
-
-
USEPA, Toxicological review of trichloroethylene (CAS No. 79-01-6). In support of summary information on the integrated risk information system (IRIS). External Review Draft. EPA/635/R-09/011A. Available from: .
-
USEPA, 2009. Toxicological review of trichloroethylene (CAS No. 79-01-6). In support of summary information on the integrated risk information system (IRIS). External Review Draft. EPA/635/R-09/011A. Available from: http://cfpub.epa.gov/ncea/CFM/recordisplay.cfm?deid=215006.
-
(2009)
-
-
-
37
-
-
77955921364
-
-
USEPA, Approaches for the Application of Physiologically Based Pharmacokinetic (PBPK) Models and Supporting Data in Risk Assessment. National Center for Environmental Assessment. Office of Research and Development, US Environmental Protection Agency, Washington, DC. EPA/600/R-05/043F.
-
USEPA, 2006. Approaches for the Application of Physiologically Based Pharmacokinetic (PBPK) Models and Supporting Data in Risk Assessment. National Center for Environmental Assessment. Office of Research and Development, US Environmental Protection Agency, Washington, DC. EPA/600/R-05/043F.
-
(2006)
-
-
-
38
-
-
34548119507
-
Extrahepatic metabolism by CYP2E1 in PBPK modeling of lipophilic volatile organic chemicals: impacts on metabolic parameter estimation and prediction of dose metrics
-
Yoon M., Madden M.C., Barton H.A. Extrahepatic metabolism by CYP2E1 in PBPK modeling of lipophilic volatile organic chemicals: impacts on metabolic parameter estimation and prediction of dose metrics. J. Toxicol. Environ. Health A 2007, 70:1527-1541.
-
(2007)
J. Toxicol. Environ. Health A
, vol.70
, pp. 1527-1541
-
-
Yoon, M.1
Madden, M.C.2
Barton, H.A.3
|