Evaluation of potential toxicity from co-exposure to three CNS depressants (toluene, ethylbenzene, and xylene) under resting and working conditions using PBPK modeling

Journal of Occupational and Environmental Hygiene

Volumn 2, Issue 3, 2005, Pages 127-135

  Dennison, James E ^a   Bigelow, Philip L ^b   Mumtaz, Moiz M ^c   Andersen, Melvin E ^d   Dobrev, Ivan D ^e   Yang, Raymond S H ^a  

^a Department of Environmental and Radiological Health Sciences   (United States)

^b INSTITUTE FOR WORK AND HEALTH   (Canada)

^c AGENCY FOR TOXIC SUBSTANCES AND DISEASE REGISTRY   (United States)

^d CIIT CENTERS FOR HEALTH RESEARCH   (United States)

^e NONE

Author keywords

Mixture formula; Mixtures; PBPK; Synergism; Unity calculation

Indexed keywords

ETHYLBENZENE; TOLUENE; XYLENE;

ARTICLE; BLOOD; CALCULATION; MAXIMUM ALLOWABLE CONCENTRATION; MODEL; OCCUPATIONAL EXPOSURE; PRIORITY JOURNAL; REST; RISK ASSESSMENT; TOXICITY; VALIDATION PROCESS;

ANIMALS; BENZENE DERIVATIVES; DRUG INTERACTIONS; ENERGY METABOLISM; HUMANS; MODELS, ANIMAL; MODELS, BIOLOGICAL; OCCUPATIONAL EXPOSURE; REPRODUCIBILITY OF RESULTS; RISK ASSESSMENT; TOLUENE; WORKLOAD; WORKPLACE; XYLENES;

EID: 15444364182     PISSN: 15459624     EISSN: None     Source Type: Journal    
DOI: 10.1080/15459620590916198     Document Type: Article

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