메뉴 건너뛰기




Volumn 166, Issue 1-3, 2007, Pages 352-359

PBPK models in risk assessment-A focus on chloroprene

Author keywords

Chloroprene; IRIS; PBPK model; Risk assessment; Toxicokinetic

Indexed keywords

CHLOROPRENE;

EID: 33947133630     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbi.2007.01.016     Document Type: Article
Times cited : (13)

References (19)
  • 2
    • 33947096656 scopus 로고    scopus 로고
    • US EPA, Glossary of Integrated Risk Information System (IRIS) Terms, Available at: http://www.epa.gov/iris/gloss8.htm#b.
  • 3
    • 26444453754 scopus 로고    scopus 로고
    • Improving the development and use of biologically based dose response models (BBDR) in risk assessment
    • DeWoskin R.S., Barone Jr. S., Clewell H.J., and Setzer R.W. Improving the development and use of biologically based dose response models (BBDR) in risk assessment. Hum. Ecol. Risk Assess. 7 5 (2001) 1091-1120
    • (2001) Hum. Ecol. Risk Assess. , vol.7 , Issue.5 , pp. 1091-1120
    • DeWoskin, R.S.1    Barone Jr., S.2    Clewell, H.J.3    Setzer, R.W.4
  • 5
    • 11344264355 scopus 로고    scopus 로고
    • Framework for evaluation of physiologically-based pharmacokinetic models for use in safety or risk assessment
    • Clark L.H., Setzer R.W., and Barton H.A. Framework for evaluation of physiologically-based pharmacokinetic models for use in safety or risk assessment. Risk Anal. 24 6 (2004) 1697-1717
    • (2004) Risk Anal. , vol.24 , Issue.6 , pp. 1697-1717
    • Clark, L.H.1    Setzer, R.W.2    Barton, H.A.3
  • 6
    • 33947138409 scopus 로고    scopus 로고
    • US EPA, Integrated Risk Information System (IRIS) Home Page, Available at: http://www.epa.gov/iris/index.html.
  • 8
    • 33947167954 scopus 로고    scopus 로고
    • R.S. DeWoskin, J.C. Lipscomb, C. Thompson, W. Chiu, P. Schlosser, C. Smallwood, J. Swartout, L. Teuschler, A. Marcus, in: J.C. Lipscomb, E.V. Ohanian (Eds.), Pharmacokinetic/Physiologically Based Pharmacokinetic Models in Integrated Risk Information System Assessments, Chapter 15 in Toxicokinetics and Risk Assessment, CRC Press, ISBN: 0849337224, 2006.
  • 11
  • 12
    • 33947185973 scopus 로고    scopus 로고
    • Chloroprene: overview of studies under consideration for the development of an IRIS Assessment
    • September 21 TBD-reference in this proceedings issue of Chemical-Biological Interactions
    • Pagan I. Chloroprene: overview of studies under consideration for the development of an IRIS Assessment. IISRP Symposium on Evaluation of Butadiene & Chloroprene Health Effects. September 21 (2005) TBD-reference in this proceedings issue of Chemical-Biological Interactions
    • (2005) IISRP Symposium on Evaluation of Butadiene & Chloroprene Health Effects
    • Pagan, I.1
  • 13
    • 2442700338 scopus 로고    scopus 로고
    • Kinetic modeling of beta-chloroprene metabolism. I. In vitro rates in liver and lung tissue fractions from mice, rats, hamsters, and humans
    • Himmelstein M.W., Carpenter S.C., and Hinderliter P.M. Kinetic modeling of beta-chloroprene metabolism. I. In vitro rates in liver and lung tissue fractions from mice, rats, hamsters, and humans. Toxicol. Sci. 79 1 (2004) 18-27
    • (2004) Toxicol. Sci. , vol.79 , Issue.1 , pp. 18-27
    • Himmelstein, M.W.1    Carpenter, S.C.2    Hinderliter, P.M.3
  • 14
    • 2442660322 scopus 로고    scopus 로고
    • Kinetic modeling of beta-chloroprene metabolism. II. The application of physiologically based modeling for cancer dose response analysis
    • Himmelstein M.W., Carpenter S.C., Evans M.V., Hinderliter P.M., and Kenyon E.M. Kinetic modeling of beta-chloroprene metabolism. II. The application of physiologically based modeling for cancer dose response analysis. Toxicol. Sci. 79 1 (2004) 28-37
    • (2004) Toxicol. Sci. , vol.79 , Issue.1 , pp. 28-37
    • Himmelstein, M.W.1    Carpenter, S.C.2    Evans, M.V.3    Hinderliter, P.M.4    Kenyon, E.M.5
  • 15
    • 0021279862 scopus 로고
    • A physiologically based description of the inhalation pharmacokinetics of styrene in rats and humans
    • Ramsey J.C., and Andersen M.E. A physiologically based description of the inhalation pharmacokinetics of styrene in rats and humans. Toxicol. Appl. Pharmacol. 73 (1984) 159-175
    • (1984) Toxicol. Appl. Pharmacol. , vol.73 , pp. 159-175
    • Ramsey, J.C.1    Andersen, M.E.2
  • 16
    • 33947119868 scopus 로고    scopus 로고
    • Kinetic modeling of β-chloroprene metabolism: default and physiologically-based modeling approaches for cancer dose response
    • September 21 TBD-reference in this proceedings issue of Chemical-Biological Interactions
    • Himmelstein M.W., Leonard R., and Valentine R. Kinetic modeling of β-chloroprene metabolism: default and physiologically-based modeling approaches for cancer dose response. IISRP Symposium on Evaluation of Butadiene & Chloroprene Health Effects. September 21 (2005) TBD-reference in this proceedings issue of Chemical-Biological Interactions
    • (2005) IISRP Symposium on Evaluation of Butadiene & Chloroprene Health Effects
    • Himmelstein, M.W.1    Leonard, R.2    Valentine, R.3
  • 17
    • 0035177945 scopus 로고    scopus 로고
    • In vitro metabolism of chloroprene: species differences, epoxide stereochemistry and a de-chlorination pathway
    • Cottrell L., Golding B.T., Munter T., and Watson W.P. In vitro metabolism of chloroprene: species differences, epoxide stereochemistry and a de-chlorination pathway. Chem. Res. Toxicol. 14 11 (2001) 1552-1562
    • (2001) Chem. Res. Toxicol. , vol.14 , Issue.11 , pp. 1552-1562
    • Cottrell, L.1    Golding, B.T.2    Munter, T.3    Watson, W.P.4
  • 18
    • 33947108056 scopus 로고    scopus 로고
    • T. Munter, L. Cottrell, R. Ghai, B.T. Golding, W.P. Watson, The metabolism and molecular toxicology of chloroprene, Chem. Biol. Interact. (2006) (Epub ahead of print).
  • 19
    • 33947125733 scopus 로고    scopus 로고
    • U.S. Environmental Protection Agency, Washington, DC Available online at: http://www.epa.gov/iris/toxreviews/1001-tr.pdf
    • U.S. Environmental Protection Agency. Toxicological Review of Vinyl Chloride, EPA 635/R-00/004 (2000), U.S. Environmental Protection Agency, Washington, DC. http://www.epa.gov/iris/toxreviews/1001-tr.pdf Available online at: http://www.epa.gov/iris/toxreviews/1001-tr.pdf
    • (2000) Toxicological Review of Vinyl Chloride, EPA 635/R-00/004
    • U.S. Environmental Protection Agency1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.