Revised assessment of cancer risk to dichloromethane II. Application of probabilistic methods to cancer risk determinations

Regulatory Toxicology and Pharmacology

Volumn 45, Issue 1, 2006, Pages 55-65

  David, Raymond M ^a   Clewell, Harvey J ^b   Gentry, P Robinan ^c   Covington, Tammie R ^c   Morgott, David A ^a   Marino, Dale J ^a  

^a EASTMAN KODAK COMPANY   (United States)

^b CIIT CENTERS FOR HEALTH RESEARCH   (United States)

^c ENVIRON Health Sciences Institute   (United States)

Author keywords

Bayesian analysis; Dichloromethane; GST polymorphism; Methylene chloride; Monte Carlo analysis; PBPK modeling; Risk assessment

Indexed keywords

CARCINOGEN; DICHLOROMETHANE; GLUTATHIONE TRANSFERASE;

ARTICLE; BAYES THEOREM; CALIBRATION; CANCER INCIDENCE; CANCER RISK; DATA ANALYSIS; ENVIRONMENTAL PROTECTION; GENETIC POLYMORPHISM; GOVERNMENT; HUMAN; LIVER CANCER; LUNG CANCER; METABOLISM; MONTE CARLO METHOD; PRIORITY JOURNAL; PROBABILITY; PROCESS MODEL; RISK ASSESSMENT; UNITED STATES;

CARCINOGENS; DOSE-RESPONSE RELATIONSHIP, DRUG; GLUTATHIONE TRANSFERASE; HUMANS; INHALATION EXPOSURE; MARKOV CHAINS; METHYLENE CHLORIDE; MODELS, BIOLOGICAL; MONTE CARLO METHOD; NEOPLASMS; POLYMORPHISM, GENETIC; RISK ASSESSMENT;

EID: 33646090140     PISSN: 02732300     EISSN: 10960295     Source Type: Journal    
DOI: 10.1016/j.yrtph.2005.12.003     Document Type: Article

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