Assessing the toxic effects of ethylene glycol ethers using Quantitative Structure Toxicity Relationship models

Toxicology and Applied Pharmacology

Volumn 254, Issue 2, 2011, Pages 198-205

  Ruiz, Patricia ^a   Mumtaz, Moiz ^a   Gombar, Vijay ^b  

^a AGENCY FOR TOXIC SUBSTANCES AND DISEASE REGISTRY   (United States)

^b ELI LILLY AND COMPANY   (United States)

Author keywords

Developmental toxicity; Ethylene glycol mono n alkyl ethers; QSAR; QSTR; Quantitative structure toxicity relationship

Indexed keywords

2 BUTOXYETHANOL; 2 ETHOXYETHANOL; 2 METHOXYETHANOL; 2 PROPOXYETHANOL; ALCOHOL; ALKOXYETHANOL; ETHER DERIVATIVE; ETHYLENE GLYCOL DERIVATIVE; ETHYLENE GLYCOL ETHER; ETHYLENE GLYCOL MONO N ALKYL ETHER; UNCLASSIFIED DRUG;

AMES TEST; ANIMAL EXPERIMENT; CARCINOGENICITY; CONCISE INTERNATIONAL CHEMICAL ASSESSMENT DOCUMENT; CONTROLLED STUDY; DEVELOPMENTAL TOXICITY; DOCUMENT EXAMINATION; FEMALE; HEALTH CARE ORGANIZATION; MALE; MOLECULAR MODEL; MOUSE; MUTAGENICITY; NONHUMAN; QUANTITATIVE STRUCTURE ACTIVITY RELATION; QUANTITATIVE STRUCTURE TOXICITY RELATIONSHIP; RAT; REVIEW; TOXICOLOGY; WORLD HEALTH ORGANIZATION;

ANIMALS; ETHERS; ETHYLENE GLYCOL; FEMALE; MALE; MICE; MODELS, BIOLOGICAL; MUTAGENICITY TESTS; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; RATS;

RODENTIA;

EID: 79959922934     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2010.10.024     Document Type: Review

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