Resistance of Leishmania donovani to sodium stibogluconate is related to the expression of host and parasite γ-glutamylcysteine synthetase

Antimicrobial Agents and Chemotherapy

Volumn 50, Issue 1, 2006, Pages 88-95

  Carter, K C ^a   Hutchison, S ^a   Henriquez, F L ^b   Legare D ^b   Ouellette, M ^b   Roberts, C W ^a   Mullen, A B ^a  

^a UNIVERSITY OF STRATHCLYDE   (United Kingdom)

^b LAVAL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIMONY; CHOLESTEROL; DICETYL PHOSPHATE; GLUTAMATE CYSTEINE LIGASE; GLUTATHIONE; NONIONIC SURFACTANT; STIBOGLUCONATE SODIUM; TETRAETHYLENE GLYCOL HEXADECYL ETHER; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MARROW; CELL PROTECTION; CONTROLLED STUDY; DRUG FORMULATION; DRUG MECHANISM; DRUG SENSITIVITY; DRUG SOLUTION; DRUG TRANSPORT; FEMALE; GENE EXPRESSION; GENE SEQUENCE; GENETIC POLYMORPHISM; HEAVY CHAIN; HOST PARASITE INTERACTION; IN VITRO STUDY; LEISHMANIA DONOVANI; LEISHMANIASIS; LIPID VESICLE; LIVER; MACROPHAGE; MALE; MONOTHERAPY; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; PRIORITY JOURNAL; SPLEEN; STRAIN DIFFERENCE; TISSUE SPECIFICITY;

ANIMALS; ANTIMONY SODIUM GLUCONATE; DRUG RESISTANCE; GLUTAMATE-CYSTEINE LIGASE; LEISHMANIA DONOVANI; LEISHMANIASIS, VISCERAL; MICE; MICE, INBRED BALB C;

EID: 29944447375     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.50.1.88-95.2006     Document Type: Article

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