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Volumn 112, Issue 5, 2012, Pages 711-718

Endurance training stimulates growth and survival pathways and the redox balance in rat pancreatic islets

Author keywords

AKT; Bcl 2 Bax ratio; Caspase 3; ERK; Redox status

Indexed keywords


EID: 84859581443     PISSN: 87507587     EISSN: 15221601     Source Type: Journal    
DOI: 10.1152/japplphysiol.00318.2011     Document Type: Article
Times cited : (20)

References (45)
  • 1
    • 34247574598 scopus 로고    scopus 로고
    • A role of FRK in regulation of embryonal pancreatic beta cell formation
    • DOI 10.1016/j.mce.2007.02.009, PII S0303720707000986
    • Akerblom B, Annerén C, Welsh M. A role of FRK in regulation of embryonal pancreatic beta cell formation. Mol Cell Endocrinol 270: 73-78, 2007. (Pubitemid 46670553)
    • (2007) Molecular and Cellular Endocrinology , vol.270 , Issue.1-2 , pp. 73-78
    • Akerblom, B.1    Anneren, C.2    Welsh, M.3
  • 2
    • 0028828451 scopus 로고
    • Ionic mechanisms involved in the regulation of insulin secretion by muscarinic agonists
    • Bordin S, Boschero AC, Carneiro EM, Atwater I. Ionic mechanisms involved in the regulation of insulin secretion by muscarinic agonists. J Membr Biol 148: 177-184, 1995.
    • (1995) J Membr Biol , vol.148 , pp. 177-184
    • Bordin, S.1    Boschero, A.C.2    Carneiro, E.M.3    Atwater, I.4
  • 3
    • 48449102210 scopus 로고    scopus 로고
    • Rab GTPase-activating protein AS160 is a major downstream effector of protein kinase B/Akt signaling in pancreatic beta-cells
    • Bouzakri K, Ribaux P, Tomas A, Parnaud G, Rickenbach K, Halban PA. Rab GTPase-activating protein AS160 is a major downstream effector of protein kinase B/Akt signaling in pancreatic beta-cells. Diabetes 57: 1195-1204, 2008.
    • (2008) Diabetes , vol.57 , pp. 1195-1204
    • Bouzakri, K.1    Ribaux, P.2    Tomas, A.3    Parnaud, G.4    Rickenbach, K.5    Halban, P.A.6
  • 4
    • 77951685571 scopus 로고    scopus 로고
    • The role of exercise-induced myokines in muscle homeostasis and the defense against chronic diseases
    • Brandt C, Pedersen BK. The role of exercise-induced myokines in muscle homeostasis and the defense against chronic diseases. J Biomed Biotechnol 2010: 520258, 2010.
    • (2010) J Biomed Biotechnol , vol.2010 , pp. 520258
    • Brandt, C.1    Pedersen, B.K.2
  • 5
    • 34948813565 scopus 로고    scopus 로고
    • Leptin decreases apoptosis and alters BCL-2: Bax ratio in clonal rodent pancreatic beta-cells
    • DOI 10.1002/dmrr.726
    • Brown JE, Dunmore SJ. Leptin decreases apoptosis and alters BCL-2: Bax ratio in clonal rodent pancreatic beta-cells. Diabetes Metab Res Rev 23: 497-502, 2007. (Pubitemid 47520908)
    • (2007) Diabetes/Metabolism Research and Reviews , vol.23 , Issue.6 , pp. 497-502
    • Brown, J.E.P.1    Dunmore, S.J.2
  • 6
    • 79951786896 scopus 로고    scopus 로고
    • Endurance training activates AMP-activated kinase, increases expression of uncoupling protein 2 and reduces insulin secretion from rat pancreatic islets
    • Calegari VC, Zoppi CC, Rezende LF, Silveira LR, Carneiro EM, Boschero AC. Endurance training activates AMP-activated kinase, increases expression of uncoupling protein 2 and reduces insulin secretion from rat pancreatic islets. J Endocrinol 208: 257-264, 2011.
    • (2011) J Endocrinol , vol.208 , pp. 257-264
    • Calegari, V.C.1    Zoppi, C.C.2    Rezende, L.F.3    Silveira, L.R.4    Carneiro, E.M.5    Boschero, A.C.6
  • 7
    • 34547438354 scopus 로고    scopus 로고
    • Role of Akt substrate of 160 kDa in insulin-stimulated and contraction-stimulated glucose transport
    • Cartee GD, Wojtaszewski JF. Role of Akt substrate of 160 kDa in insulin-stimulated and contraction-stimulated glucose transport. Appl Physiol Nutr Metab 32: 557-566, 2007.
    • (2007) Appl Physiol Nutr Metab , vol.32 , pp. 557-566
    • Cartee, G.D.1    Wojtaszewski, J.F.2
  • 8
    • 33747884524 scopus 로고    scopus 로고
    • Exercise and dexamethasone oppositely modulate beta-cell function and survival via independent pathways in 90% pancreatectomized rats
    • DOI 10.1677/joe.1.06400
    • Choi SB, Jang JS, Hong SM, Jun DW, Park S. Exercise and dexamethasone oppositely modulate beta-cell function and survival via independent pathways in 90% pancreatectomized rats. J Endocrinol 190: 471-482, 2006. (Pubitemid 44288383)
    • (2006) Journal of Endocrinology , vol.190 , Issue.2 , pp. 471-482
    • Choi, S.B.1    Jang, J.S.2    Hong, S.M.3    Jun, D.W.4    Park, S.5
  • 9
    • 45249122276 scopus 로고    scopus 로고
    • Fatty acids and glucolipotoxicity in the pathogenesis of Type 2 diabetes
    • DOI 10.1042/BST0360348
    • Cnop M. Fatty acids and glucolipotoxicity in the pathogenesis of Type 2 diabetes. Biochem Soc Trans 36: 348-352, 2008. (Pubitemid 351839329)
    • (2008) Biochemical Society Transactions , vol.36 , Issue.3 , pp. 348-352
    • Cnop, M.1
  • 10
    • 4444271002 scopus 로고    scopus 로고
    • Exercise training prevents and protects streptozotocin-induced oxidative stress and beta-cell damage in rat pancreas
    • DOI 10.1620/tjem.203.145
    • Coskun O, Ocakci A, Bayraktaroglu T, Kanter M. Exercise training prevents and protects streptozotocin-induced oxidative stress and beta-cell damage in rat pancreas. Tohoku J Exp Med 203: 145-154, 2004. (Pubitemid 39162080)
    • (2004) Tohoku Journal of Experimental Medicine , vol.203 , Issue.3 , pp. 145-154
    • Coskun, O.1    Ocakci, A.2    Bayraktaroglu, T.3    Kanter, M.4
  • 11
    • 33749344947 scopus 로고    scopus 로고
    • ERK1/2 control phosphorylation and protein level of cAMP-responsive element-binding protein: A key role in glucose-mediated pancreatic beta-cell survival
    • DOI 10.2337/db05-1618
    • Costes S, Broca C, Bertrand G, Lajoix AD, Bataille D, Bockaert J, Dalle S. ERK1/2 control phosphorylation and protein level of cAMPresponsive element-binding protein: a key role in glucose-mediated pancreatic beta-cell survival. Diabetes 55: 2220-2230, 2006. (Pubitemid 44743618)
    • (2006) Diabetes , vol.55 , Issue.8 , pp. 2220-2230
    • Costes, S.1    Broca, C.2    Bertrand, G.3    Lajoix, A.-D.4    Bataille, D.5    Bockaert, J.6    Dalle, S.7
  • 12
    • 77954644287 scopus 로고    scopus 로고
    • Acute exercise reduces hepatic glucose production through inhibition of the Foxo1/HNF-4alpha pathway in insulin resistant mice
    • De Souza CT, Frederico MJ, da Luz G, Cintra DE, Ropelle ER, Pauli JR, Velloso LA. Acute exercise reduces hepatic glucose production through inhibition of the Foxo1/HNF-4alpha pathway in insulin resistant mice. J Physiol 588: 2239-2253, 2010.
    • (2010) J Physiol , vol.588 , pp. 2239-2253
    • De Souza, C.T.1    Frederico, M.J.2    Da Luz, G.3    Cintra, D.E.4    Ropelle, E.R.5    Pauli, J.R.6    Velloso, L.A.7
  • 13
    • 3242656480 scopus 로고    scopus 로고
    • Pancreatic beta-cell growth and survival in the onset of type 2 diabetes: A role for protein kinase B in the Akt?
    • DOI 10.1152/ajpendo.00031.2004
    • Dickson LM, Rhodes CJ. Pancreatic beta-cell growth and survival in the onset of type 2 diabetes: a role for protein kinase B in the Akt? Am J Physiol Endocrinol Metab 287: E192-E198, 2004. (Pubitemid 38943882)
    • (2004) American Journal of Physiology - Endocrinology and Metabolism , vol.287 , Issue.2
    • Dickson, L.M.1    Rhodes, C.J.2
  • 14
    • 67649233039 scopus 로고    scopus 로고
    • Akt and PTEN: Beta-cell mass and pancreas plasticity
    • Elghazi L, Bernal-Mizrachi E. Akt and PTEN: beta-cell mass and pancreas plasticity. Trends Endocrinol Metab 20: 243-251, 2009.
    • (2009) Trends Endocrinol Metab , vol.20 , pp. 243-251
    • Elghazi, L.1    Bernal-Mizrachi, E.2
  • 15
    • 0030865646 scopus 로고    scopus 로고
    • Dual regulation of caspase activity by hydrogen peroxide: Implications for apoptosis
    • DOI 10.1016/S0014-5793(97)01068-5, PII S0014579397010685
    • Hampton MB, Orrenius S. Dual regulation of caspase activity by hydrogen peroxide: implications for apoptosis. FEBS Lett 414: 552-556, 1997. (Pubitemid 27390666)
    • (1997) FEBS Letters , vol.414 , Issue.3 , pp. 552-556
    • Hampton, M.B.1    Orrenius, S.2
  • 16
    • 4644235275 scopus 로고    scopus 로고
    • Exercise as a therapeutic intervention for the prevention and treatment of insulin resistance
    • DOI 10.1002/dmrr.505
    • Hawley JA. Exercise as a therapeutic intervention for the prevention and treatment of insulin resistance. Diabetes Metab Res Rev 20: 383-393, 2004. (Pubitemid 39302963)
    • (2004) Diabetes/Metabolism Research and Reviews , vol.20 , Issue.5 , pp. 383-393
    • Hawley, J.A.1
  • 17
    • 37249066135 scopus 로고    scopus 로고
    • Exercise training-induced improvements in insulin action
    • DOI 10.1111/j.1748-1716.2007.01783.x
    • Hawley JA, Lessard SJ. Exercise training-induced improvements in insulin action. Acta Physiol (Oxf) 192: 127-135, 2008. (Pubitemid 350265363)
    • (2008) Acta Physiologica , vol.192 , Issue.1 , pp. 127-135
    • Hawley, J.A.1    Lessard, S.J.2
  • 18
    • 0032589599 scopus 로고    scopus 로고
    • Antioxidants, NFkappaB activation and diabetogenesis
    • Ho E, Bray TM. Antioxidants, NFkappaB activation and diabetogenesis. Proc Soc Exp Biol Med 222: 205-213, 1999.
    • (1999) Proc Soc Exp Biol Med , vol.222 , pp. 205-213
    • Ho, E.1    Bray, T.M.2
  • 19
    • 58149313601 scopus 로고    scopus 로고
    • Acute regulation of metabolic genes and insulin receptor substrates in the liver of mice by one single bout of treadmill exercise
    • Hoene M, Lehmann R, Hennige AM, Pohl AK, Haring HU, Schleicher ED, Weigert C. Acute regulation of metabolic genes and insulin receptor substrates in the liver of mice by one single bout of treadmill exercise. J Physiol 587: 241-252, 2009.
    • (2009) J Physiol , vol.587 , pp. 241-252
    • Hoene, M.1    Lehmann, R.2    Hennige, A.M.3    Pohl, A.K.4    Haring, H.U.5    Schleicher, E.D.6    Weigert, C.7
  • 22
    • 0025959695 scopus 로고
    • Coordinate reduction of rat pancreatic islet glucokinase and proinsulin mRNA by exercise training
    • Koranyi LI, Bourey RE, Slentz CA, Holloszy JO, Permutt MA. Coordinate reduction of rat pancreatic islet glucokinase and proinsulin mRNA by exercise training. Diabetes 40: 401-404, 1991.
    • (1991) Diabetes , vol.40 , pp. 401-404
    • Koranyi, L.I.1    Bourey, R.E.2    Slentz, C.A.3    Holloszy, J.O.4    Permutt, M.A.5
  • 23
    • 0014042613 scopus 로고
    • Method for the isolation of intact islets of Langerhans from the rat pancreas
    • Lacy PE, Kostianovsky M. Method for the isolation of intact islets of Langerhans from the rat pancreas. Diabetes 16: 35-39, 1967.
    • (1967) Diabetes , vol.16 , pp. 35-39
    • Lacy, P.E.1    Kostianovsky, M.2
  • 26
    • 37249074327 scopus 로고    scopus 로고
    • The protein kinases ERK1/2 and their roles in pancreatic beta cells
    • DOI 10.1111/j.1748-1716.2007.01785.x
    • Lawrence M, Shao C, Duan L, McGlynn K, Cobb MH. The protein kinases ERK1/2 and their roles in pancreatic beta cells. Acta Physiol (Oxf) 192: 11-17, 2008. (Pubitemid 350265365)
    • (2008) Acta Physiologica , vol.192 , Issue.1 , pp. 11-17
    • Lawrence, M.1    Shao, C.2    Duan, L.3    McGlynn, K.4    Cobb, M.H.5
  • 28
    • 0029984682 scopus 로고    scopus 로고
    • Low antioxidant enzyme gene expression in pancreatic islets compared with various other mouse tissues
    • DOI 10.1016/0891-5849(96)02051-5
    • Lenzen S, Drinkgern J, Tiedge M. Low antioxidant enzyme gene expression in pancreatic islets compared with various other mouse tissues. Free Radic Biol Med 20: 463-466, 1996. (Pubitemid 26077870)
    • (1996) Free Radical Biology and Medicine , vol.20 , Issue.3 , pp. 463-466
    • Lenzen, S.1    Drinkgern, J.2    Tiedge, M.3
  • 30
    • 0033032444 scopus 로고    scopus 로고
    • Hydrogen peroxide-induced apoptosis in HL-60 cells requires caspase-3 activation
    • Matsura T, Kai M, Fujii Y, Ito H, Yamada K. Hydrogen peroxideinduced apoptosis in HL-60 cells requires caspase-3 activation. Free Radic Res 30: 73-83, 1999. (Pubitemid 29129415)
    • (1999) Free Radical Research , vol.30 , Issue.1 , pp. 73-83
    • Matsura, T.1    Kai, M.2    Fujii, Y.3    Ito, H.4    Yamada, K.5
  • 31
    • 0036787462 scopus 로고    scopus 로고
    • Metabolic and autocrine regulation of the mammalian target of rapamycin by pancreatic beta-cells
    • McDaniel ML, Marshall CA, Pappan KL, Kwon G. Metabolic and autocrine regulation of the mammalian target of rapamycin by pancreatic beta-cells. Diabetes 51: 2877-2885, 2002.
    • (2002) Diabetes , vol.51 , pp. 2877-2885
    • McDaniel, M.L.1    Marshall, C.A.2    Pappan, K.L.3    Kwon, G.4
  • 32
    • 78650518771 scopus 로고    scopus 로고
    • Modulation of Bcl-2-related protein expression in pancreatic beta cells by pro-inflammatory cytokines and its dependence on the antioxidative defense status
    • Mehmeti I, Lenzen S, Lortz S. Modulation of Bcl-2-related protein expression in pancreatic beta cells by pro-inflammatory cytokines and its dependence on the antioxidative defense status. Mol Cell Endocrinol 332: 88-96, 2011.
    • (2011) Mol Cell Endocrinol , vol.332 , pp. 88-96
    • Mehmeti, I.1    Lenzen, S.2    Lortz, S.3
  • 34
    • 77957087406 scopus 로고    scopus 로고
    • Exercise at anaerobic threshold intensity and insulin secretion by isolated pancreatic islets of rats
    • Oliveira CA, Paiva MF, Mota CA, Ribeiro C, Leme JA, Luciano E, Mello MA. Exercise at anaerobic threshold intensity and insulin secretion by isolated pancreatic islets of rats. Islets 2: 240-246, 2010.
    • (2010) Islets , vol.2 , pp. 240-246
    • Oliveira, C.A.1    Paiva, M.F.2    Mota, C.A.3    Ribeiro, C.4    Leme, J.A.5    Luciano, E.6    Mello, M.A.7
  • 35
    • 34247490186 scopus 로고    scopus 로고
    • Mitochondria, oxidative stress and cell death
    • DOI 10.1007/s10495-007-0756-2, Special Issue on Mitochondria in Apoptosis
    • Ott M, Gogvadze V, Orrenius S, Zhivotovsky B. Mitochondria, oxidative stress and cell death. Apoptosis 12: 913-922, 2007. (Pubitemid 46653300)
    • (2007) Apoptosis , vol.12 , Issue.5 , pp. 913-922
    • Ott, M.1    Gogvadze, V.2    Orrenius, S.3    Zhivotovsky, B.4
  • 37
    • 0344298914 scopus 로고    scopus 로고
    • Exercise training-induced alterations in skeletal muscle antioxidant capacity: A brief review
    • DOI 10.1097/00005768-199907000-00011
    • Powers SK, Ji LL, Leeuwenburgh C. Exercise training-induced alterations in skeletal muscle antioxidant capacity: a brief review. Med Sci Sports Exerc 31: 987-997, 1999. (Pubitemid 29316195)
    • (1999) Medicine and Science in Sports and Exercise , vol.31 , Issue.7 , pp. 987-997
    • Powers, S.K.1    Ji, L.L.2    Leeuwenburgh, C.3
  • 38
    • 70349398318 scopus 로고    scopus 로고
    • Beta-cell deterioration during diabetes: What's in the gun?
    • Robertson RP. Beta-cell deterioration during diabetes: what's in the gun? Trends Endocrinol Metab 20: 388-393, 2009.
    • (2009) Trends Endocrinol Metab , vol.20 , pp. 388-393
    • Robertson, R.P.1
  • 40
    • 0030814369 scopus 로고    scopus 로고
    • Acute and chronic effects of exercise on baroreflexes in spontaneously hypertensive rats
    • Silva GJ, Brum PC, Negrão CE, Krieger EM. Acute and chronic effects of exercise on baroreflexes in spontaneously hypertensive rats. Hypertension 30: 714-719, 1997. (Pubitemid 27444261)
    • (1997) Hypertension , vol.30 , Issue.SUPPL. 3 II , pp. 714-719
    • Silva, G.J.J.1    Brum, P.C.2    Negrao, C.E.3    Krieger, E.M.4
  • 41
    • 0032537608 scopus 로고    scopus 로고
    • Cytochrome c release and caspase activation in hydrogen peroxide- and tributyltin-induced apoptosis
    • DOI 10.1016/S0014-5793(98)00630-9, PII S0014579398006309
    • Stridh H, Kimland M, Jones DP, Orrenius S, Hampton MB. Cytochrome c release and caspase activation in hydrogen peroxide- and tributyltin-induced apoptosis. FEBS Lett 429: 351-355, 1998. (Pubitemid 28300390)
    • (1998) FEBS Letters , vol.429 , Issue.3 , pp. 351-355
    • Stridh, H.1    Kimland, M.2    Jones, D.P.3    Orrenius, S.4    Hampton, M.B.5


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