Enhanced expression of neuronal nitric oxide synthase in islets of exercise-trained rats

Biochemical and Biophysical Research Communications

Volumn 312, Issue 3, 2003, Pages 794-800

  Ueda, Hiroshi ^a   Urano, Yuriko ^a   Sakurai, Tomonobu ^a   Kizaki, Takako ^b   Hitomi, Yoshiaki ^b   Ohno, Hideki ^b   Izawa, Tetsuya ^a  

^a TOKYO METROPOLITAN UNIVERSITY   (Japan)

^b KYORIN UNIVERSITY   (Japan)

Author keywords

Cytochrome c reductase; Exercise training; Glucokinase; Glucose transporter 2; Insulin secretion; Islet; Neuronal nitric oxide synthase; Nitric oxide; Rat

Indexed keywords

CALMODULIN; GLUCOKINASE; GLUCOSE TRANSPORTER; GLUCOSE TRANSPORTER 2; GLUT 2 PROTEIN; GLUT-2 PROTEIN; NEURAL CONSTITUTIVE NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE;

ANIMAL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOSYNTHESIS; CATALYSIS; CELL CULTURE; COMPARATIVE STUDY; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME RELEASE; ENZYME SYNTHESIS; ENZYMOLOGY; EXERCISE; GLUCONEOGENESIS; GLUCOSE UTILIZATION; INSULIN RELEASE; MALE; METABOLISM; NERVE CELL; NONHUMAN; PANCREAS ISLET; PANCREAS ISLET CELL; PHYSIOLOGY; PRIORITY JOURNAL; PROTEIN CONTENT; PROTEIN EXPRESSION; RAT; REDUCTION; RUNNING; SPECIES COMPARISON; TRAINING;

EID: 0345415089     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2003.10.189     Document Type: Article

References (29)

1. Matschinsky F.M. A lesson in metabolic regulation inspired by the glucokinase glucose sensor paradigm. Diabetes. 45:1996;223-241.
2. Schuit F.C., Huypens P., Heimberg H., Pipeleers D.G. Glucose sensing in pancreatic β-cells. Diabetes. 50:2001;1-11.
3. King D.S., Dalsky G.P., Staten M.A., Clutter W.E., Van Houten D.R., Holloszy J.O. Insulin action and secretion in endurance-trained and untrained humans. J. Appl. Physiol. 63:1982;2247-2252.
4. Mikines K.J., Sonne B., Farrell P.A., Tronier B., Galbo H. Effect of training on the dose-response relationship for insulin action in men. J. Appl. Physiol. 66:1989;695-703.
5. Zawalich W., Maturo S., Felig P. Influence of physical training on insulin release and glucose utilization by islet cells and liver glucokinase activity in the rat. Am. J. Physiol. 243:1982;E464-E469.
6. Koranyi L.I., Bourey R.E., Slentz C.A., Holloszy J.O., Permutt M.A. Coordinate reduction of rat pancreatic islet glucokinase and proinsulin mRNA by exercise training. Diabetes. 40:1991;401-404.
7. Farrell P.A., Caston A.L., Rodd D., Engdahl J. Effect of training on insulin secretion from single pancreatic beta cells. Med. Sci. Sports Exerc. 24:1992;426-433.
8. Spinas G.A. The dual role of nitric oxide in islet beta-cells. News Physiol. Sci. 14:1999;49-54.
9. + channels through suppression of phosphofructokinase activity and inhibits glucose-induced insulin release in pancreatic β-cells. J. Gen. Physiol. 104:1994;1079-1099.
10. Åkesson B., Henningsson R., Salehi A., Lundquist I. Islet constitutive nitric oxide synthase and glucose regulation of insulin release in mice. J. Endocrinol. 163:1999;39-48.
11. Schmidt H.H.H.W., Warner T.D., Ishii K., Sheng H., Murad F. Insulin secretion from pancreatic B cells caused by L-arginine-derived nitrogen oxides. Science. 255:1992;721-723.
12. Laffranchi R., Gogvadze V., Richter C., Spinas G.A. Nitric oxide (nitrogen monoxide, NO) stimulates insulin secretion by inducing calcium release from mitochondria. Biochem. Biophys. Res. Commun. 217:1995;584-591.
13. Yan D., Rana R.S. Nitric oxide does not initiate but potentiates glucose-induced insulin secretion in pancreatic beta-cells. Biochem. Biophys. Res. Commun. 251:1998;699-703.
14. Lajoix A.-D., Reggio H., Chardès T., Péraldi-Roux S., Tribillac F., Roye M., Dietz S., Broca C., Manteghetti M., Ribes G., Wollheim C.B., Gross R. A neuronal isoform of nitric oxide synthase expressed in pancreatic β-cells controls insulin secretion. Diabetes. 50:2001;1311-1323.
15. Ma Z., Landt M., Bohrer A., Ramanadham S., Kipnis D.M., Turk J. Interleukin-1 reduces the glycolytic utilization of glucose by pancreatic islets and reduces glucokinase mRNA content and protein synthesis by a nitric oxide-dependent mechanism. J. Biol. Chem. 272:1997;17827-17835.
16. Beggs M., Beresford G., Clarke J., Mertz R., Espinal J., Hammonds P. Interleukin-1 β inhibits glucokinase activity in clonal HIT-T15 β-cells. FEBS Lett. 267:1990;217-220.
17. Park C., Kim J., Shim J., Kang B., Park Y., Nam K., Lee Y., Kim C. Inhibitory effects of streptozotocin, tumor necrosis factor-α, and interleukin-1β on glucokinase activity in pancreatic islets and gene expression of GLUT2 and glucokinase. Arch. Biochem. Biophys. 362:1999;217-224.
18. Balon T.W. Integrative biology of nitric oxide and exercise. Exerc. Sport Sci. Rev. 27:1999;219-253.
19. 2+ and lipolysis in adipocytes from exercise-trained rats. J. Appl. Physiol. 77:1994;2618-2624.
20. Gotoh M., Maki T., Kiyoizumi T., Satomi S., Monaco A.P. An improved method for the isolation of mouse pancreatic islets. Transplantation. 40:1985;437-438.
21. Rossetti L., Chen W., Hu M., Hawkins M., Brazilai N., Efrat S. Abnormal regulation of HGP by hyperglycemia in mice with a disrupted glucokinase allele. Am. J. Physiol. 273:1997;E743-E750.
22. Thompson M., Becker L., Bryant D., Williams G., Levin D., Margraf L., Giroir B.P. Expression of the inducible nitric oxide synthase gene in diaphragm and skeletal muscle. J. Appl. Physiol. 81:1996;2415-2420.
23. Martásek P., Miller R.T., Roman L.J., Shea T., Masters B.S.S. Assay of isoforms of Escherichia coli-expressed nitric oxide synthase. Methods Enzymol. 301:1999;70-78.
24. Giroix M., Sener A., Pipeleers D.G., Malaisse W.J. Hexose metabolism in pancreatic islets. Biochem. J. 223:1984;47-53.
25. Stallknecht B., Roesdahl M., Vinten J., Capito K., Galbo H. The effect of lesions of the sympathoadrenal system of training induced adaptations in adipocytes and pancreatic islets in rats. Acta Physiol. Scand. 156:1996;465-473.
26. Schuit F., Moens K., Heimberg H., Pipeleers D. Cellular origin of hexokinase in pancreatic islets. J. Biol. Chem. 274:1999;32803-32809.
27. Malaisse W.J., Sener A., Levy J. The stimulus-secretion coupling of glucose-induced insulin release. Fasting-induced adaptation of key glycolytic enzymes in isolated islets. J. Biol. Chem. 251:1976;1731-1737.
28. Klatt P., Schmidt K., Uray G., Mayer B. Multiple catalytic functions of brain nitric oxide synthase. J. Biol. Chem. 268:1993;14781-14787.
29. Cunningham J.M., Green I.C. Cytokine, nitric oxide and insulin secreting cells. Growth Regul. 4:1994;173-180.