-
1
-
-
0016290780
-
Further evidence that insulin resistance exists in patients with chemical diabetes
-
Ginsberg H, Olefsky JM, Reaven GM (1974) Further evidence that insulin resistance exists in patients with chemical diabetes. Diabetes 23: 674-678.
-
(1974)
Diabetes
, vol.23
, pp. 674-678
-
-
Ginsberg, H.1
Olefsky, J.M.2
Reaven, G.M.3
-
2
-
-
0029618228
-
Epidemiologic studies on the pathogenesis of non-insulindependent diabetes mellitus (NIDDM)
-
Harris MI (1995) Epidemiologic studies on the pathogenesis of non-insulindependent diabetes mellitus (NIDDM). Clin Invest Med 18: 231-239.
-
(1995)
Clin Invest Med
, vol.18
, pp. 231-239
-
-
Harris, M.I.1
-
3
-
-
55649105963
-
Clinical risk factors, DNA variants, and the development of type 2 diabetes
-
Lyssenko V, Jonsson A, Almgren P, Pulizzi N, Isomaa B, et al. (2008) Clinical risk factors, DNA variants, and the development of type 2 diabetes. N Engl J Med 359: 2220-2232.
-
(2008)
N Engl J Med
, vol.359
, pp. 2220-2232
-
-
Lyssenko, V.1
Jonsson, A.2
Almgren, P.3
Pulizzi, N.4
Isomaa, B.5
-
4
-
-
0017924236
-
The role of insulin resistance in the pathogenesis of diabetes mellitus
-
Reaven GM, Olefsky JM (1978) The role of insulin resistance in the pathogenesis of diabetes mellitus. Adv Metab Disord 9: 313-331.
-
(1978)
Adv Metab Disord
, vol.9
, pp. 313-331
-
-
Reaven, G.M.1
Olefsky, J.M.2
-
5
-
-
0014898491
-
Comparison of impedance to insulin-mediated glucose uptake in normal subjects and in subjects with latent diabetes
-
Shen SW, Reaven GM, Farquhar JW (1970) Comparison of impedance to insulin-mediated glucose uptake in normal subjects and in subjects with latent diabetes. J Clin Invest 49: 2151-2160.
-
(1970)
J Clin Invest
, vol.49
, pp. 2151-2160
-
-
Shen, S.W.1
Reaven, G.M.2
Farquhar, J.W.3
-
6
-
-
0025663581
-
Slow glucose removal rate and hyperinsulinemia precede the development of type II diabetes in the offspring of diabetic parents
-
Warram JH, Martin BC, Krolewski AS, Soeldner JS, Kahn CR (1990) Slow glucose removal rate and hyperinsulinemia precede the development of type II diabetes in the offspring of diabetic parents. Ann Intern Med 113: 909-915.
-
(1990)
Ann Intern Med
, vol.113
, pp. 909-915
-
-
Warram, J.H.1
Martin, B.C.2
Krolewski, A.S.3
Soeldner, J.S.4
Kahn, C.R.5
-
7
-
-
0026021161
-
A multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia, and atherosclerotic cardiovascular disease
-
Insulin resistance
-
DeFronzo RA, Ferrannini E (1991) Insulin resistance. A multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia, and atherosclerotic cardiovascular disease. Diabetes Care 14: 173-194.
-
(1991)
Diabetes Care
, vol.14
, pp. 173-194
-
-
Defronzo, R.A.1
Ferrannini, E.2
-
8
-
-
34547235853
-
Insulin resistance, insulin response, and obesity as indicators of metabolic risk
-
Ferrannini E, Balkau B, Coppack SW, Dekker JM, Mari A, et al. (2007) Insulin resistance, insulin response, and obesity as indicators of metabolic risk. J Clin Endocrinol Metab 92: 2885-2892.
-
(2007)
J Clin Endocrinol Metab
, vol.92
, pp. 2885-2892
-
-
Ferrannini, E.1
Balkau, B.2
Coppack, S.W.3
Dekker, J.M.4
Mari, A.5
-
9
-
-
0033860359
-
Insulin resistance and cardiovascular disease
-
Ginsberg HN (2000) Insulin resistance and cardiovascular disease. J Clin Invest 106: 453-458.
-
(2000)
J Clin Invest
, vol.106
, pp. 453-458
-
-
Ginsberg, H.N.1
-
10
-
-
0343209773
-
Insulin sensitivity and atherosclerosis
-
The Insulin Resistance Atherosclerosis Study (IRAS) Investigators
-
Howard G, O'Leary DH, Zaccaro D, Haffner S, Rewers M, et al. (1996) Insulin sensitivity and atherosclerosis. The Insulin Resistance Atherosclerosis Study (IRAS) Investigators. Circulation 93: 1809-1817.
-
(1996)
Circulation
, vol.93
, pp. 1809-1817
-
-
Howard, G.1
O'Leary, D.H.2
Zaccaro, D.3
Haffner, S.4
Rewers, M.5
-
11
-
-
0031726145
-
Resistance to insulin-mediated glucose disposal as a predictor of cardiovascular disease
-
Yip J, Facchini FS, Reaven GM (1998) Resistance to insulin-mediated glucose disposal as a predictor of cardiovascular disease. J Clin Endocrinol Metab 83: 2773-2776.
-
(1998)
J Clin Endocrinol Metab
, vol.83
, pp. 2773-2776
-
-
Yip, J.1
Facchini, F.S.2
Reaven, G.M.3
-
13
-
-
64649104158
-
Banting Lecture. From the triumvirate to the ominous octet: A new paradigm for the treatment of type 2 diabetes mellitus
-
Defronzo RA (2009) Banting Lecture. From the triumvirate to the ominous octet: a new paradigm for the treatment of type 2 diabetes mellitus. Diabetes 58: 773-795.
-
(2009)
Diabetes
, vol.58
, pp. 773-795
-
-
Defronzo, R.A.1
-
14
-
-
0032786924
-
Insulin resistance: A chicken that has come to roost
-
Reaven GM (1999) Insulin resistance: a chicken that has come to roost. Ann N Y Acad Sci 892: 45-57.
-
(1999)
Ann N Y Acad Sci
, vol.892
, pp. 45-57
-
-
Reaven, G.M.1
-
15
-
-
0021054652
-
Insulin secretion and action in noninsulin-dependent diabetes mellitus. Is insulin resistance secondary to hypoinsulinemia?
-
Reaven GM, Chen YI, Coulston AM, Greenfield MS, Hollenbeck C, et al. (1983) Insulin secretion and action in noninsulin-dependent diabetes mellitus. Is insulin resistance secondary to hypoinsulinemia? Am J Med 75: 85-93.
-
(1983)
Am J Med
, vol.75
, pp. 85-93
-
-
Reaven, G.M.1
Chen, Y.I.2
Coulston, A.M.3
Greenfield, M.S.4
Hollenbeck, C.5
-
16
-
-
34249665642
-
Orchestration of glucose homeostasis: From a small acorn to the California oak
-
Bergman RN (2007) Orchestration of glucose homeostasis: from a small acorn to the California oak. Diabetes 56: 1489-1501.
-
(2007)
Diabetes
, vol.56
, pp. 1489-1501
-
-
Bergman, R.N.1
-
17
-
-
38349006256
-
Current approaches for assessing insulin sensitivity and resistance in vivo: Advantages, limitations, and appropriate usage
-
Muniyappa R, Lee S, Chen H, Quon MJ (2008) Current approaches for assessing insulin sensitivity and resistance in vivo: advantages, limitations, and appropriate usage. Am J Physiol Endocrinol Metab 294: E15-26.
-
(2008)
Am J Physiol Endocrinol Metab
, vol.294
-
-
Muniyappa, R.1
Lee, S.2
Chen, H.3
Quon, M.J.4
-
18
-
-
67049173139
-
Discovery of metabolomics biomarkers for early detection of nephrotoxicity
-
Boudonck KJ, Mitchell MW, Nemet L, Keresztes L, Nyska A, et al. (2009) Discovery of metabolomics biomarkers for early detection of nephrotoxicity. Toxicol Pathol 37: 280-292.
-
(2009)
Toxicol Pathol
, vol.37
, pp. 280-292
-
-
Boudonck, K.J.1
Mitchell, M.W.2
Nemet, L.3
Keresztes, L.4
Nyska, A.5
-
19
-
-
44949233606
-
Analysis of the adult human plasma metabolome
-
Lawton KA, Berger A, Mitchell M, Milgram KE, Evans AM, et al. (2008) Analysis of the adult human plasma metabolome. Pharmacogenomics 9: 383-397.
-
(2008)
Pharmacogenomics
, vol.9
, pp. 383-397
-
-
Lawton, K.A.1
Berger, A.2
Mitchell, M.3
Milgram, K.E.4
Evans, A.M.5
-
20
-
-
60149091657
-
Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression
-
Sreekumar A, Poisson LM, Rajendiran TM, Khan AP, Cao Q, et al. (2009) Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression. Nature 457: 910-914.
-
(2009)
Nature
, vol.457
, pp. 910-914
-
-
Sreekumar, A.1
Poisson, L.M.2
Rajendiran, T.M.3
Khan, A.P.4
Cao, Q.5
-
21
-
-
33745095399
-
Retinol-binding protein 4 and insulin resistance in lean, obese, and diabetic subjects
-
Graham TE, Yang Q, Bluher M, Hammarstedt A, Ciaraldi TP, et al. (2006) Retinol-binding protein 4 and insulin resistance in lean, obese, and diabetic subjects. N Engl J Med 354: 2552-2563.
-
(2006)
N Engl J Med
, vol.354
, pp. 2552-2563
-
-
Graham, T.E.1
Yang, Q.2
Bluher, M.3
Hammarstedt, A.4
Ciaraldi, T.P.5
-
22
-
-
49649083576
-
Insulin resistance and hyperinsulinemia: You can't have one without the other
-
Kim SH, Reaven GM (2008) Insulin resistance and hyperinsulinemia: you can't have one without the other. Diabetes Care 31: 1433-1438.
-
(2008)
Diabetes Care
, vol.31
, pp. 1433-1438
-
-
Kim, S.H.1
Reaven, G.M.2
-
23
-
-
0030792915
-
Insulin sensitivity, vascular reactivity, and clamp-induced vasodilatation in essential hypertension
-
Natali A, Taddei S, Quinones Galvan A, Camastra S, Baldi S, et al. (1997) Insulin sensitivity, vascular reactivity, and clamp-induced vasodilatation in essential hypertension. Circulation 96: 849-855.
-
(1997)
Circulation
, vol.96
, pp. 849-855
-
-
Natali, A.1
Taddei, S.2
Quinones, G.A.3
Camastra, S.4
Baldi, S.5
-
24
-
-
33846031943
-
Muscle and liver insulin resistance indexes derived from the oral glucose tolerance test
-
Abdul-Ghani MA, Matsuda M, Balas B, DeFronzo RA (2007) Muscle and liver insulin resistance indexes derived from the oral glucose tolerance test. Diabetes Care 30: 89-94.
-
(2007)
Diabetes Care
, vol.30
, pp. 89-94
-
-
Abdul-Ghani, M.A.1
Matsuda, M.2
Balas, B.3
Defronzo, R.A.4
-
25
-
-
0016423016
-
The formation of 2-hydroxybutyric acid in experimental animals
-
Landaas S (1975) The formation of 2-hydroxybutyric acid in experimental animals. Clin Chim Acta 58: 23-32.
-
(1975)
Clin Chim Acta
, vol.58
, pp. 23-32
-
-
Landaas, S.1
-
26
-
-
0000903690
-
Reduction of alpha-ketobutyrate by human serum
-
Rosalki SB, Wilkinson JH (1960) Reduction of alpha-ketobutyrate by human serum. Nature 188: 1110-1111.
-
(1960)
Nature
, vol.188
, pp. 1110-1111
-
-
Rosalki, S.B.1
Wilkinson, J.H.2
-
27
-
-
0015868826
-
The occurrence of 2-hydroxybutyric acid in urine from patients with lactic acidosis
-
Pettersen JE, Landaas S, Eldjarn L (1973) The occurrence of 2-hydroxybutyric acid in urine from patients with lactic acidosis. Clin Chim Acta 48: 213-219.
-
(1973)
Clin Chim Acta
, vol.48
, pp. 213-219
-
-
Pettersen, J.E.1
Landaas, S.2
Eldjarn, L.3
-
28
-
-
53549091032
-
Clinical applications of urinary organic acids. Part I: Detoxification markers
-
Lord RS, Bralley JA (2008) Clinical applications of urinary organic acids. Part I: Detoxification markers. Altern Med Rev 13: 205-215.
-
(2008)
Altern Med Rev
, vol.13
, pp. 205-215
-
-
Lord, R.S.1
Bralley, J.A.2
-
29
-
-
46349084465
-
Bioinformatics analysis of targeted metabolomics-uncovering old and new tales of diabetic mice under medication
-
Altmaier E, Ramsay SL, Graber A, Mewes HW, Weinberger KM, et al. (2008) Bioinformatics analysis of targeted metabolomics-uncovering old and new tales of diabetic mice under medication. Endocrinology 149: 3478-3489.
-
(2008)
Endocrinology
, vol.149
, pp. 3478-3489
-
-
Altmaier, E.1
Ramsay, S.L.2
Graber, A.3
Mewes, H.W.4
Weinberger, K.M.5
-
30
-
-
0022448076
-
Effect of alpha-ketobutyrate on palmitic acid and pyruvate metabolism in isolated rat hepatocytes
-
Brass EP (1986) Effect of alpha-ketobutyrate on palmitic acid and pyruvate metabolism in isolated rat hepatocytes. Biochim Biophys Acta 888: 18-24.
-
(1986)
Biochim Biophys Acta
, vol.888
, pp. 18-24
-
-
Brass, E.P.1
-
31
-
-
0016808514
-
Clinical conditions associated with urinary excretion of 2-hydroxybutyric acid
-
Landaas S, Pettersen JE (1975) Clinical conditions associated with urinary excretion of 2-hydroxybutyric acid. Scand J Clin Lab Invest 35: 259-266.
-
(1975)
Scand J Clin Lab Invest
, vol.35
, pp. 259-266
-
-
Landaas, S.1
Pettersen, J.E.2
-
32
-
-
34247842731
-
A metabolomic comparison of urinary changes in type 2 diabetes in mouse, rat, and human
-
Salek RM, Maguire ML, Bentley E, Rubtsov DV, Hough T, et al. (2007) A metabolomic comparison of urinary changes in type 2 diabetes in mouse, rat, and human. Physiol Genomics 29: 99-108.
-
(2007)
Physiol Genomics
, vol.29
, pp. 99-108
-
-
Salek, R.M.1
Maguire, M.L.2
Bentley, E.3
Rubtsov, D.V.4
Hough, T.5
-
33
-
-
0035350549
-
Inhibition of in vitro CO2 production and lipid synthesis by 2-hydroxybutyric acid in rat brain
-
Silva AR, Ruschel C, Helegda C, Wyse AT, Wannmacher CM, et al. (2001) Inhibition of in vitro CO2 production and lipid synthesis by 2-hydroxybutyric acid in rat brain. Braz J Med Biol Res 34: 627-631.
-
(2001)
Braz J Med Biol Res
, vol.34
, pp. 627-631
-
-
Silva, A.R.1
Ruschel, C.2
Helegda, C.3
Wyse, A.T.4
Wannmacher, C.M.5
-
34
-
-
0021964118
-
Defect in alpha-ketobutyrate metabolism: A new inborn error
-
Yang W, Roth KS (1985) Defect in alpha-ketobutyrate metabolism: a new inborn error. Clin Chim Acta 145: 173-182.
-
(1985)
Clin Chim Acta
, vol.145
, pp. 173-182
-
-
Yang, W.1
Roth, K.S.2
-
35
-
-
11944256550
-
Glutathione infusion potentiates glucose-induced insulin secretion in aged patients with impaired glucose tolerance
-
Paolisso G, Giugliano D, Pizza G, Gambardella A, Tesauro P, et al. (1992) Glutathione infusion potentiates glucose-induced insulin secretion in aged patients with impaired glucose tolerance. Diabetes Care 15: 1-7.
-
(1992)
Diabetes Care
, vol.15
, pp. 1-7
-
-
Paolisso, G.1
Giugliano, D.2
Pizza, G.3
Gambardella, A.4
Tesauro, P.5
-
36
-
-
63449111894
-
A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance
-
Newgard CB, An J, Bain JR, Muehlbauer MJ, Stevens RD, et al. (2009) A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance. Cell Metab 9: 311-326.
-
(2009)
Cell Metab
, vol.9
, pp. 311-326
-
-
Newgard, C.B.1
An, J.2
Bain, J.R.3
Muehlbauer, M.J.4
Stevens, R.D.5
-
37
-
-
38449112372
-
Role of dietary proteins and amino acids in the pathogenesis of insulin resistance
-
Tremblay F, Lavigne C, Jacques H, Marette A (2007) Role of dietary proteins and amino acids in the pathogenesis of insulin resistance. Annu Rev Nutr 27: 293-310.
-
(2007)
Annu Rev Nutr
, vol.27
, pp. 293-310
-
-
Tremblay, F.1
Lavigne, C.2
Jacques, H.3
Marette, A.4
-
38
-
-
1842844418
-
The EGIR-RISC STUDY (The European Group for the Study of Insulin Resistance: Relationship between insulin sensitivity and cardiovascular disease risk): I. Methodology and objectives
-
Hills S, Balkau B, Coppack S, Dekker J, Mari A, et al. (2004) The EGIR-RISC STUDY (The European Group for the Study of Insulin Resistance: relationship between insulin sensitivity and cardiovascular disease risk): I. Methodology and objectives. Diabetologia 47: 566-570.
-
(2004)
Diabetologia
, vol.47
, pp. 566-570
-
-
Hills, S.1
Balkau, B.2
Coppack, S.3
Dekker, J.4
Mari, A.5
-
39
-
-
68849083050
-
Integrated, Nontargeted Ultrahigh Performance Liquid Chromatography/Electrospray Ionization Tandem Mass Spectrometry Platform for the Identification and Relative Quantification of the Small-Molecule Complement of Biological Systems
-
Evans AM, Dehaven CD, Barrett T, Mitchell M, Milgram E. (2009) Integrated, Nontargeted Ultrahigh Performance Liquid Chromatography/Electrospray Ionization Tandem Mass Spectrometry Platform for the Identification and Relative Quantification of the Small-Molecule Complement of Biological Systems. Anal Chem.
-
(2009)
Anal Chem
-
-
Evans, A.M.1
Dehaven, C.D.2
Barrett, T.3
Mitchell, M.4
Milgram, E.5
-
40
-
-
0035478854
-
Random Forest
-
Breiman L (2001) Random Forest. Machine Learning 45: 5-32.
-
(2001)
Machine Learning
, vol.45
, pp. 5-32
-
-
Breiman, L.1
-
41
-
-
0345040873
-
Classification and Regression by random Forest
-
Liaw A, Wiener M (2002) Classification and Regression by random Forest. R News 2: 18-22.
-
(2002)
R News
, vol.2
, pp. 18-22
-
-
Liaw, A.1
Wiener, M.2
|