The relationship between cell membrane damage and lipid peroxidation under the condition of hypoxia-reoxygenation: Analysis of the mechanism using antioxidants and electron transport inhibitors

Cell Biochemistry and Function

Volumn 27, Issue 6, 2009, Pages 338-343

  Yajima, Daisuke ^a   Motani, Hisako ^a   Hayakawa, Mutsumi ^a   Sato, Yayoi ^a   Sato, Kaoru ^a   Iwase, Hirotaro ^a  

^a CHIBA UNIVERSITY   (Japan)

Author keywords

Antioxidant; Cell membrane damage; Electron transport inhibitor; Hypoxia reoxygenation; Lipid peroxidation

Indexed keywords

ACETYLCYSTEINE; ANTIMYCIN A1; ANTIOXIDANT; POTASSIUM CYANIDE; ROTENONE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; ELECTRON TRANSPORT; EMBRYO; FLUORESCENCE ANALYSIS; HYPOXIA; ISCHEMIA; LIPID PEROXIDATION; MEMBRANE DAMAGE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; REOXYGENATION; REPERFUSION;

ANIMALS; ANTIOXIDANTS; CELL DEATH; CELL HYPOXIA; CELL MEMBRANE; CELL MEMBRANE PERMEABILITY; CELLS, CULTURED; ELECTRON TRANSPORT; FLUORESCENT DYES; LIPID PEROXIDATION; MICE; OXYGEN; REACTIVE OXYGEN SPECIES; REPERFUSION INJURY; TIME FACTORS;

EID: 70349376417     PISSN: 02636484     EISSN: 10990844     Source Type: Journal    
DOI: 10.1002/cbf.1578     Document Type: Article

References (28)

1. Vanlangenakker N, Vanden Berghe T, Krysko DV, Festjens N, Vandenabeele P. Molecular mechanisms and pathophysiology of necrotic cell death. Curr Mol Med 2008; 8: 207-220.
2. Ide T, Tsutsumi H, Kinugawa S, et al. Mitochondrial electron transport complex 1 is a potential source of oxygen free radical in the failing myocardium. Circ Res 1999; 11: 376-381.
3. Szewczyk A, Wojtczak L. Mitochondria as a pharmacological target. Pharmacol Rev 2002; 54: 101-127.
4. Liu Y, Fiskum G, Schubert D. Generation of reactive oxygen species by the mitochondrial electron transport chain. J Neurochem 2002; 80: 780-787.
5. Fariss MW, Chan CB, Patel M, Van Houten B, Orrenius S. Role of mitochondria in toxic oxidative stress. Mol Interv 2005; 5: 94-111.
6. Vera A-V, Chinopoulos C. Bioenergetics and the formation of mitochondrial reactive oxygen species. Trends Pharmacol Sci 2006; 27: 639-645.
7. Levraut J, Iwase H, Shao ZH, Vanden Hoek TL, Schumacker PT. Cell death during ischemia: relationship to mitochondrial depolarization and ROS generation. Am J Physiol Heart Circ Physiol 2003; 284: 549-558.
8. Robin E, Guzy RD, Loor G, et al. Oxidant stress during simulated ischemia primes cardiomyocytes for cell death during reperfusion. J Biol Chem 2007; 282: 19133-19143.
9. Wang Q, Tompkins KD, Simonyi A, Korthuis RJ, Sun AY, Sun GY. Apocynin protects against global cerebral ischemia-reperfusion-induced oxidative stress and injury in the gerbil hippocampus. Brain Res 2006; 1090: 182-189.
10. Vanden Hoek TL, Shao ZH, Li C, Zak R, Schumacker PT, Becker LB. Reperfusion injury on cardiac myocytes after simulated ischemia. Am J Physiol 1996; 270: 1334-1341.
11. Pap EHW, Drummen GPC, Winter VJ, et al. Ratio-fluorescence microscopy of lipid oxidation in living cells using C11-BODIPY581/591. FEBS Lett 1999; 453: 278-282.
12. Roth BL, Poot M, Yue ST, Millard PJ. Bacterial viability and antibiotic susceptibility testing with SYTOX green nucleic acid stain. Appl Environ Microbiol 1997; 63: 2421-2431.
13. Becker LB, Vanden Hoek TL, Shao ZH, Li CQ, Schumacker PT. Generation of superoxide in cardiomyocytes during ischemia before reperfusion. Am J Physiol 1999; 277: 2240-2246.
14. Lebuff G, Schumacker PT, Shao ZH, Anderson T, Iwase H, Vanden Hoek TL. ROS and NO trigger early preconditioning: relationship to mitochondrial KATP channel. Am J Physiol Heart Circ Physiol 2003; 284: 299-308.
15. Vanden Hoek TL, Li C, Shao ZH, Schumacker PT, Becker LB. Significant levels of oxidants are generated by isolated cardiomyocytes during ischemia prior to reperfusion. J Mol Cell Cardiol 1997; 29: 2571-2583.
16. Yamato M, Egashira T, Utsumi H. Application of in vivo ESR spectroscopy to measurement of cerebrovascular ROS generation in stroke. Free Radic Biol Med 2003; 35: 1619-1631.
17. Villagrasa V, Cortijo J, Marti-Cabrera M, et al. Inhibitory effects of N-acetylcysteine on speroxide anion generation in human polymorphonuclear leukocytes. J Pharm Pharmacol 1997; 49: 525-529.
18. Cadenas E, Davies KJ. Mitochondrial free radical generation, oxidative stress and aging. Free Radic Biol Med 2000; 29: 222-230.
19. Dröse S, Brandt U. The mechanism of mitochondrial superoxide production by the cytochrome bc1 complex. J Biol Chem 2008; 283: 21649-21654.
20. Raha S, McEachern GE, Myint AT, Robinson EH. Superoxides from mitochondrial complex III: the role of manganese dismutase. Free Radic Biol Med. 2000; 29: 170-180.
21. Davey GP, Peuchen S, Clark JB. Energy thresholds in brain mitochondria. Potential involvement in neurodegeneration. J Biol Chem 1998; 273: 12753-12757.
22. Jacobson J, Duchen MR, Hothersall J, Clark JB, Heales SJ. Induction of mitochondrial oxidative stress in astrocytes by nitric oxide precedes disruption of energy metabolism. J Neurochem 2005; 95: 388-395.
23. Alzate JF, Arias AA, Moreno-Mateos D, Alvarez-Barrientos A, Jiménez-Ruiz A. Mitochondrial superoxide mediates heat-induced apoptotic-like death in Leishmania infantum. Mol Biochem Parasitol 2007; 152: 192-202.
24. Kashkarov KP, Vasil'eva EV, Ruuge EK. Generation of superoxide radicals by the mitochondrial respiratory chain of isolated cardiomyocytes. Biokhimiia 1994; 59: 813-818.
25. Henriquez M, Armisén R, Stutzin A, Quest AF. Cell death by necrosis, a regulated way to go. Curr Mol Med 2008; 8: 187-206.
26. Tsujimoto Y, Shimizu S. Role of the mitochondrial membrane permeability transition in cell death. Apoptosis 2007; 12: 835-840.
27. Schild L, Reiser G. Oxidative stress is involved in the permeabilization of the inner membrane of brain mitochondria exposed to hypoxia/ reoxygenation and low micromolar Ca2+. FEBS J 2005; 272: 3593-3601.
28. Iwase H, Takatori T, Nagao M, et al. Formation of keto and hydroxyl compounds of linoleic acid in submitochondrial particles of bovine heart. Free Radical Biol Med 1998; 24: 1492-1503.