Neutrophil elastase contributes to the development of ischemia-reperfusion- induced liver injury by decreasing endothelial production of prostacyclin in rats

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 287, Issue 6 50-6, 2004, Pages

  Okajima, Kenji ^a   Harada, Naoaki ^a   Uchiba, Mitsuhiro ^a   Mori, Masakazu ^a  

^a KUMAMOTO UNIVERSITY   (Japan)

Author keywords

Activated leukocytes; Endothelial cells; Tumor necrosis factor

Indexed keywords

3 ACETOXYMETHYL 2 (2 CARBOXY 1 PYRROLIDINYLCARBONYL) 7ALPHA METHOXY 8 OXO 5 THIA 1 AZABICYCLO[4.2.0]OCT 2 ENE 5,5 DIOXIDE; 6 OXOPROSTAGLANDIN F1 ALPHA; ILOPROST; INDOMETACIN; LEUKOCYTE ELASTASE; LEUKOCYTE ELASTASE INHIBITOR; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE SYNTHASE; PROSTACYCLIN; SIVELESTAT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL PERMEABILITY; CONTROLLED STUDY; DRUG INHIBITION; ENDOTHELIUM CELL; LIVER BLOOD FLOW; LIVER ISCHEMIA; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; REPERFUSION;

6-KETOPROSTAGLANDIN F1 ALPHA; ANIMALS; CAPILLARY PERMEABILITY; CEPHALOSPORINS; CHEMOKINES, CXC; CYCLOOXYGENASE INHIBITORS; ENDOTHELIUM; ENZYME INHIBITORS; EPOPROSTENOL; GLYCINE; ILOPROST; INDOMETHACIN; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LEUKOCYTE ELASTASE; LIVER; LIVER CIRCULATION; MALE; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE III; PEROXIDASE; RATS; RATS, WISTAR; REPERFUSION INJURY; SULFONAMIDES; TRANSAMINASES; VASODILATOR AGENTS;

EID: 9244219674     PISSN: 01931857     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpgi.00061.2004     Document Type: Article

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