Neuroprotective role of Neurokinin B (NKB) on β-amyloid (25-35) induced toxicity in aging rat brain synaptosomes: Involvement in oxidative stress and excitotoxicity

Biogerontology

Volumn 7, Issue 1, 2006, Pages 1-17

  Mantha, Anil K ^a   Moorthy, K ^b   Cowsik, Sudha M ^a   Baquer, Najma Z ^a  

^a JAWAHARLAL NEHRU UNIVERSITY   (India)

^b WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Aging; Amyloid beta protein; Neurokinin B (NKB); Neuroprotection; Oxidative stress and excitotoxicity; Tachykinins

Indexed keywords

AMINE OXIDASE (FLAVIN CONTAINING); AMYLOID BETA PROTEIN[25-35]; CALCIUM; GLUTAMIC ACID; N METHYL DEXTRO ASPARTIC ACID; NEUROKININ; NEUROKININ B; NEUROPEPTIDE; SUPEROXIDE DISMUTASE; AGENTS INTERACTING WITH TRANSMITTER, HORMONE OR DRUG RECEPTORS; AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN (25 35); AMYLOID BETA-PROTEIN (25-35); N METHYLASPARTIC ACID; NEUROPROTECTIVE AGENT; PEPTIDE FRAGMENT; SCAVENGER;

AGING; ANIMAL TISSUE; ARTICLE; BRAIN FUNCTION; BRAIN SYNAPTOSOME; CALCIUM BLOOD LEVEL; CONTROLLED STUDY; DEAMINATION; DEGENERATIVE DISEASE; ENZYME ACTIVITY; ENZYME ASSAY; EXCITOTOXICITY; FEMALE; NEUROMODULATION; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN FUNCTION; RAT; STATISTICAL SIGNIFICANCE; ANIMAL; BRAIN; CALCIUM SIGNALING; DRUG EFFECT; DRUG INTERACTION; IN VITRO STUDY; METABOLISM; SYNAPTOSOME; WISTAR RAT;

AGING; AMYLOID BETA-PROTEIN; ANIMALS; BRAIN; CALCIUM SIGNALING; DRUG INTERACTIONS; FEMALE; FREE RADICAL SCAVENGERS; GLUTAMIC ACID; MONOAMINE OXIDASE; N-METHYLASPARTATE; NEUROKININ B; NEUROPROTECTIVE AGENTS; NEUROTRANSMITTER AGENTS; OXIDATIVE STRESS; PEPTIDE FRAGMENTS; RATS; RATS, WISTAR; SUPEROXIDE DISMUTASE; SYNAPTOSOMES;

EID: 33745257258     PISSN: 13895729     EISSN: 15736768     Source Type: Journal    
DOI: 10.1007/s10522-005-6043-0     Document Type: Article

References (68)

1. BN Ames MK Shigenaga TM Hagen 1993 Oxidants, antioxidants and the degenerative diseases of aging Proc Natl Acad Sci USA 90 7915-7922 1:CAS:528:DyaK3sXmtVSksL4%3D 8367443
2. M Arundine M Tymianski 2003 Molecular mechanisms of calcium-dependent neurodegeneration in excitotoxicity Cell Calcium 34 325-337 10.1016/ S0143-4160(03)00141-6 1:CAS:528:DC%2BD3sXlvFGgs78%3D 12909079
3. R Barker 1991 Substance P and neurodegenerative disorders A speculative review Neuropeptides 20 73-78 10.1016/0143-4179(91)90054-M 1:CAS:528:DyaK3MXmslKktb4%3D 1724684
4. MS Benedetti P Dostert 1989 Monoamine oxidase, brain aging and degenerative diseases Biochem Pharmacol 38 555-561
5. R Bhatia H Lin R Lal 2000 Fresh and globular amyloid beta protein (1-42) induces rapid cellular degeneration: Evidence for amyloid channel-mediated cellular toxicity FASEB J 14 1233-1243 1:CAS:528:DC%2BD3cXjvFyjt7c%3D 10834945
6. B Boyd 2000 Ongoing progress in the Alzheimer's disease arena Drug News Perspect 13 425-438 1:STN:280:DC%2BD3szpvVSitg%3D%3D 12937614
7. MM Bradford 1976 A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding Anal Biochem 72 248-254 10.1016/0003-2697(76)90527-3 1:CAS:528:DyaE28XksVehtrY%3D 942051
8. JM Burgunder WS Young III 1989 Neurons with neurokinin B mRNA in the rat magnocellular basal nucleus: Distribution, projection and colocalization studies J Chem Neuroanat 2 239-251 1:STN:280:By%2BD38jjtFA%3D 2478159
9. SM Cardoso CR Oliveira 2003 Inhibition of NF-kB renders cells more vulnerable to apoptosis induced by amyloid beta peptides Free Radic Res 37 967-973 1:CAS:528:DC%2BD3sXotVWgsLc%3D 14670004
10. 2+ rises and consequent oxygen radical production J Neurosci 18 7727-7738 1:CAS:528:DyaK1cXntVWksrw%3D 9742143
11. GN Catravas J Takenaga CG McHale 1977 Effect of chronic administration of morphine on monoamine oxidase activity in discrete regions of the brain of rats Biochem Pharmacol 26 211-214 10.1016/0006-2952(77)90305-7 1:CAS:528:DyaE2sXktlems7o%3D 843390
12. S Consolo L Valzelli 1970 Brain choline acetylase and monoamine oxidase activity in normal and aggressive mice Eur J Pharmacol 13 129-130 10.1016/0014-2999(70)90193-7 1:CAS:528:DyaE3MXmt1ersQ%3D%3D 5531615
13. JT Coyle P Puttfarcken 1993 Oxidative stress, glutamate, and neurodegenerative disorders Science 262 689-695 1:CAS:528:DyaK2cXlvVek 7901908
14. G Forloni 1993 beta-Amyloid neurotoxicity Funct Neurol 8 211-225 1:STN:280:ByuD3M%2FksFI%3D 8406141
15. CW Gray AJ Patel 1995 Neurodegeneration mediated by glutamate and beta-amyloid peptide: A comparison and possible interaction Brain Res 691 169-179 10.1016/0006-8993(95)00669-H 1:CAS:528:DyaK2MXotValtLc%3D 8590049
16. LJ Greenlund TL Deckwerth EM Johnson Jr 1995 Superoxide dismutase delays neuronal apoptosis: A role for reactive oxygen species in programmed neuronal death Neuron 14 303-315 10.1016/0896-6273(95)90287-2 1:CAS:528:DyaK2MXjvFejs70%3D 7857640
17. 2+ indicators with greatly improved fluorescence properties J Biol Chem 260 3440-3450 1:CAS:528:DyaL2MXitVSmu7s%3D 3838314
18. T Harkany T Hortobagyi M Sasvari C Konya B Penke PG Luiten C Nyakas 1999a Neuroprotective approaches in experimental models of beta-amyloid neurotoxicity: Relevance to Alzheimer's disease Prog Neuropsychopharmacol Biol Psychiatry 23 963-1008 10.1016/ S0278-5846(99)00058-5 1:CAS:528:DyaK1MXmsVaqtL0%3D
19. T Harkany J Mulder M Sasvari I Abraham C Konya M Zarandi B Penke PG Luiten C Nyakas 1999b N-Methyl-D-aspartate receptor antagonist MK-801 and radical scavengers protect cholinergic nucleus basalis neurons against beta-amyloid neurotoxicity Neurobiol Dis 6 109-121 10.1006/ nbdi.1998.0230 1:CAS:528:DyaK1MXislOhtrs%3D
20. T Harkany S O'Mahony JP Kelly K Soos I Toro B Penke PG Luiten C Nyakas K Gulya BE Leonard 1998 Beta-amyloid(Phe(SO3H)24)25-35 in rat nucleus basalis induces behavioral dysfunctions, impairs learning and memory and disrupts cortical cholinergic innervation Behav Brain Res 90 133-145 10.1016/S0166-4328(97)00091-0 1:CAS:528:DyaK1cXhtVWktLs%3D 9580273
21. SS Kannurpatti PG Joshi NB Joshi 2000 Calcium sequestering ability of mitochondria modulates influx of calcium through glutamate receptor channel Neurochem Res 25 1527-1536 10.1023/A:1026602100160 1:CAS:528:DC%2BD3cXovFyhtro%3D 11152381
22. J Knoll 1993 The pharmacological basis of the beneficial effects of (-) deprenyl (selegiline) in Parkinson's and Alzheimer's diseases J. Neural Transm 40(Suppl) 69-91
23. S Koizumi M Ishiguro I Ohsawa T Morimoto C Takamura K Inoue S Kohsaka 1998 The effect of a secreted form of beta-amyloid-precursor protein on intracellular Ca2+ increase in rat cultured hippocampal neurones Br J Pharmacol 123 1483-1489 10.1038/sj.bjp.0701712 1:CAS:528:DyaK1cXislarsrg%3D 9605551
24. JE Kokoszka P Coskun LA Esposito DC Wallace 2001 Increased mitochondrial oxidative stress in the Sod2 (+/-) mouse results in the age-related decline of mitochondrial function culminating in increased apoptosis Proc Natl Acad Sci USA 98 2278-2283 10.1073/pnas.051627098 1:CAS:528:DC%2BD3MXhslKntbw%3D 11226230
25. M Lafon-Cazal S Pietri M Culcasi J Bockaert 1993 NMDA-dependent superoxide production and neurotoxicity Nature 364 535-537 10.1038/ 364535a0 1:CAS:528:DyaK3sXlslylur4%3D 7687749
26. JG Logan DJ O'Donvan 1976 Some characteristics of the noradrenaline activated ATPases of cerebral synaptic membranes J Physiol 263 246-247
27. CA Maggi 1997 The effects of tachykinins on inflammatory and immune cells Regul Pept 70 75-90 10.1016/S0167-0115(97)00029-3 1:CAS:528:DyaK2sXlsFSjsL8%3D 9272619
28. JE Maggio 1988 Tachykinins Annu Rev Neurosci 11 13-28 10.1146/ annurev.ne.11.030188.000305 1:CAS:528:DyaL1cXhvVSisbY%3D 3284438
29. AK Mantha IR Chandrashekar NZ Baquer SM Cowsik 2004 Three-dimensional structure of the mammalian tachykinin peptide neurokinin B bound to lipid micelles J Biomol Struct Dyn 22 137-148 1:CAS:528:DC%2BD2cXns1yntLs%3D 15317475
30. Mantha AK, Moorthy K, Cowsik SM and Baquer NZ (2006) Membrane associated functions of neurokinin B (NKB) on Aβ (25-35) induced toxicity in aging rat brain synaptosomes. Biogerentology. (in press)
31. S Marklund G Marklund 1974 Involvement of the super anion radicals in the autoxidation of pyrogollol and a convenient assay for superoxide dismutase Eur J Biochm 47 469-474 1:CAS:528:DyaE2MXhtlGm
32. MP Mattson 1994 Calcium and neuronal injury in Alzheimer's disease. Contributions of beta-amyloid precursor protein mismetabolism, free radicals, and metabolic compromise Ann NY Acad Sci 747 50-76 1:CAS:528:DyaK2MXovVSjsLw%3D 7847692
33. MP Mattson B Cheng D Davis K Bryant I Lieberburg RE Rydel 1992 Beta-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity J Neurosci 12 376-389 1:CAS:528:DyaK38XhvFajs74%3D 1346802
34. 2+ concentration, and neurotoxicity and increase antioxidant enzyme activities in hippocampal neurons J Neurochem 65 1740-1751 1:CAS:528:DyaK2MXotFOksL4%3D 7561872
35. KA Maubach C Cody RS Jones 1998 Tachykinins may modify spontaneous epileptiform activity in the rat entorhinal cortex in vitro by activating GABAergic inhibition Neuroscience 83 1047-1062 10.1016/ S0306-4522(97)00469-7 1:CAS:528:DyaK1cXhtFWqs7o%3D 9502245
36. + ATPase in rat brain Biochimica et Biophysica Acta 757 151-155 1:CAS:528:DyaL3sXktVahtLs%3D 6303439
37. 2+-ATPase activities in different regions of rat brain during alloxan diabetes J Neurochem 39 903-908 1:CAS:528:DyaL38Xlsl2ks7k%3D 6126523
38. B Meldrum J Garthwaite 1990 Excitatory amino acid neurotoxicity and neurodegenerative disease Trends Pharmacol Sci 11 379-387 10.1016/ 0165-6147(90)90184-A 1:CAS:528:DyaK3cXlvVCrsrk%3D 2238094
39. ML Michaelis CT Foster C Jayawickreme 1992 Regulation of calcium levels in brain tissue from adult and aged rats Mech Ageing Dev 62 291-306 10.1016/0047-6374(92)90114-S 1:CAS:528:DyaK38XitFWlu7g%3D 1583914
40. D Muralikrishnan M Ebadi 2001 SKF-38393, a dopamine receptor antagonist, attenuates 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity Brain Res 892 241-247 10.1016/S0006-8993(00)02994-2 1:CAS:528:DC%2BD3MXhtFSmt7c%3D 11172770
41. DG Nicholls MW Ward 2000 Mitochondrial membrane potential and neuronal glutamate excitotoxicity: Mortality and millivolts. Trends Neurosci 23 166-174 10.1016/S0166-2236(99)01534-9 1:CAS:528:DC%2BD3cXhvVOltLk%3D 10717676
42. Y Niwa O Iizawa K Ishimoto H Akamatsu T Kanoh 1993 Age-dependent basal level and induction capacity of copper-zinc and manganese superoxide dismutase and other scavenging enzyme activities in leukocytes from young and elderly adults Am J Pathol 143 312-320 1:CAS:528:DyaK3sXmt1amtL4%3D 8317554
43. RA Omar YJ Chyan AC Andorn B Poeggeler NK Robakis MA Pappolla 1999 Increased Expression but Reduced Activity of Antioxidant Enzymes in Alzheimer's Disease J Alzheimers Dis 1 139-145 1:CAS:528:DC%2BD3MXkvFyisA%3D%3D 12213999
44. L Oreland CG Gottfries 1986 Brain and brain monoamine oxidase in aging and in dementia of Alzheimer's type Prog Neuropsychopharmacol Biol Psychiatry 10 533-540 10.1016/0278-5846(86)90023-0 1:CAS:528:DyaL2sXmsFSnuw%3D%3D 3797686
45. NM Page RJ Woods PJ Lowry 2001 A regulatory role for neurokinin B in placental physiology and pre-eclampsia Regul Pept 98 97-104 10.1016/ S0167-0115(00)00239-1 1:CAS:528:DC%2BD3MXhsVOjt7k%3D 11231038
46. CJ Pike N Ramezan-Arab CW Cotman 1997 Beta-amyloid neurotoxicity in vitro: Evidence of oxidative stress but not protection by antioxidants J Neurochem 69 1601-1611 1:CAS:528:DyaK2sXmsVCksbo%3D 9326289
47. ZH Qin Y Wang TN Chase 1996 Stimulation of N-methyl-D-aspartate receptors induces apoptosis in rat brain Brain Res 725 166-176 1:CAS:528:DyaK28XjvFCqurs%3D 8836522
48. D Regoli A Boudon JL Fauchere 1994 Receptors and antagonists for substance P and related peptides Pharmacol Rev 46 551-599 1:CAS:528:DyaK2MXjs12htro%3D 7534932
49. J Saura AM Luque M Cesura M Prada Da V Chan-Palay G Huber J Loeffler JG Richards 1994 Increased monoamine oxidase B activity in plaque-associated astrocytes of Alzheimer brains revealed by quantitative enzyme radioautography Neuroscience 62 15-30 10.1016/ 0306-4522(94)90311-5 1:STN:280:ByqC3Mros1w%3D 7816197
50. JB Schulz DR Henshaw D Siwek BG Jenkins RJ Ferrante PB Cipolloni NW Kowall BR Rosen MF Beal 1995 Involvement of free radicals in excitotoxicity in vivo J Neurochem 64 2239-2247 1:CAS:528:DyaK2MXltFygu74%3D 7536809
51. M Solti T Bartfai 1987 Tachykinin regulation of serotonin release: enhancement of [3H]serotonin release from rat cerebral cortex by neuromedin K and substance P acting at distinct receptor sites Brain Res 401 377-380 10.1016/0006-8993(87)91424-7 1:CAS:528:DyaL2sXps1Oksg%3D%3D 2434195
52. P Somogyi JV Priestley AC Cuello AD Smith JP Bolam 1982 Synaptic connections of substance P-immunoreactive nerve terminals in the substantia nigra of the rat. A correlated light- and electron-microscopic study Cell Tissue Res 223 469-486 10.1007/ BF00218469 1:STN:280:Bi2B3szmsVc%3D 6178509
53. W Song LJ Zhou SX Zheng XZ Zhu 2000 Amyloid-beta 25-35 peptide induces expression of monoamine oxidase B in cultured rat astrocytes Acta Pharmacol Sin 21 557-563 1:CAS:528:DC%2BD3cXktlygsbc%3D 11360691
54. 2+ levels in cultured rat astrocytes Neurosci Lett 243 121-124 10.1016/S0304-3940(98)00106-2 1:CAS:528:DyaK1cXhtlOgsro%3D 9535128
55. CB Thompson 1995 Apoptosis in the pathogenesis and treatment of disease Science 267 1456-1462 1:CAS:528:DyaK2MXktlClt70%3D 7878464
56. M Tomaszewicz LG Micossi H Bielarczyk D Luszawska I Santarelli A Szutowicz 1991 Differential effects of angiotensin II and eledoisin on monoamine oxidase A and B activities in rat brain J Neurochem 56 729-732 1:CAS:528:DyaK3MXhtlKlurg%3D 1899693
57. CM Troy ML Shelanski 1994 Down regulation of Copper/Zinc superoxide dismutase causes apoptotic death in pcl2 neuronal cells Proc Natl Acad Sci USA 91 6383-6387
58. E Turska L Lachowicz W Koziolkiewicz T Wasiak 1985 Effects of analogues of substance P fragments on the MAO activity in rat brain Gen Pharmacol 16 293-295 1:CAS:528:DyaL2MXktFOhu7g%3D 2410326
59. S Varadarajan J Kanski M Aksenova C Lauderback DA Butterfield 2001 Different mechanisms of oxidative stress and neurotoxicity for Alzheimer's A beta(1-42) and A beta(25-35) J Am Chem Soc 123 5625-5631 10.1021/ja010452r 1:CAS:528:DC%2BD3MXjvVWisrw%3D 11403592
60. O Vergun AI Sobolevsky MV Yelshansky J Keelan BI Khodorov MR Duchen 2001 Exploration of the role of reactive oxygen species in glutamate neurotoxicity in rat hippocampal neurones in culture J Physiol 531 147-163 10.1111/j.1469-7793.2001.0147j.x 1:CAS:528:DC%2BD3MXitlSltL8%3D 11179399
61. M Vertechy MB Cooper O Ghirardi MT Ramacci 1993 The effect of age on the activity of enzymes of peroxide metabolism in rat brain Exp Gerontol 28 77-85 10.1016/0531-5565(93)90022-6 1:CAS:528:DyaK3sXhs1Grt78%3D 8382167
62. PC Waldmeier R Kam K Stocklin 1978 Increased dopamine metabolism in rat striatum after infusions of substance P into the substantia nigra Brain Res 159 223-227 10.1016/0006-8993(78)90124-5 1:CAS:528:DyaE1MXmslSgsQ%3D%3D 728796
63. GL Wenk LM Baker JD Stoehr B Hauss-Wegrzyniak W Danysz 1998 Neuroprotection by novel antagonists at the NMDA receptor channel and glycineB sites Eur J Pharmacol 347 183-187 10.1016/S0014-2999(98)00112-5 1:CAS:528:DyaK1cXivVGjtLs%3D 9653879
64. GL Wenk NE Rance SL Mobley 1995 Effects of excitatory amino acid lesions upon neurokinin B and acetylcholine neurons in the nucleus basalis of the rat Brain Res 679 8-14 10.1016/0006-8993(95)00187-U 1:CAS:528:DyaK2MXlsFCiur8%3D 7544224
65. GL Wenk W Zajaczkowski W Danysz 1997 Neuroprotection of acetylcholinergic basal forebrain neurons by memantine and neurokinin B Behav Brain Res 83 129-133 10.1016/S0166-4328(97)86056-1 1:CAS:528:DyaK2sXhs1yrsL4%3D 9062671
66. W Weyler CC Titlow JI Salach 1990 Catalytically active monoamine oxidase type A from human liver expressed in Saccharomyces cerevisiae contains covalent FAD Biochem Biophys Res Commun 173 1205-1211 10.1016/ S0006-291X(05)80914-3 1:CAS:528:DyaK3MXnslCrtw%3D%3D 2125217
67. R Wojtkowiak E Turska L Lachowicz W Koziolkiewicz 1990 Effects of N- and C-terminal fragments of substance P on ATPase and monoamine oxidase activities in rat brain Gen Pharmacol 21 403-406 1:CAS:528:DyaK3cXkvFWmsLk%3D 1696230
68. BA Yankner LK Duffy DA Kirschner 1990 Neurotrophic and neurotoxic effects of amyloid protein: Reversal by tachykinin neuropeptides Science 250 279-282 1:CAS:528:DyaK3MXlslansg%3D%3D 2218531