Inhibition of bacterial DD-peptidases (penicillin-binding proteins) in membranes and in vivo by peptidoglycan-mimetic boronic acids

Biochemistry

Volumn 51, Issue 13, 2012, Pages 2804-2811

  Dzhekieva, Liudmila ^a   Kumar, Ish ^b   Pratt, R F ^a  

^a WESLEYAN UNIVERSITY   (United States)

^b FAIRLEIGH DICKINSON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE SITE STRUCTURE; BACILLUS SUBTILIS; BACTERIAL PEPTIDOGLYCAN BIOSYNTHESIS; BINDING CONFORMATIONS; BORONIC ACID; DISSOCIATION CONSTANT; E. COLI; HOMOGENEOUS SOLUTIONS; IN-VIVO; KINETICS STUDIES; MEMBRANE PREPARATION; MEMBRANE-BOUND; PENICILLIN-BINDING PROTEINS; REACTIVE CONFORMATION; TRANSITION STATE; WHOLE CELL;

BIOCHEMISTRY; DISSOCIATION; ESCHERICHIA COLI; EXPERIMENTS; MOLECULAR MASS;

ENZYMES;

BACTERIAL PROTEIN; BORONIC ACID DERIVATIVE; PENICILLIN BINDING PROTEIN; PENICILLIN BINDING PROTEIN 5; PENICILLIN BINDING PROTEIN2; PENICILLIN G; PEPTIDASE; PEPTIDOGLYCAN; UNCLASSIFIED DRUG;

ARTICLE; BACILLUS SUBTILIS; BACTERIAL CELL; BACTERIAL MEMBRANE; CONTROLLED STUDY; DISSOCIATION CONSTANT; ENZYME CONFORMATION; ENZYME INHIBITION; ESCHERICHIA COLI; FLUORESCENCE; IN VIVO STUDY; MOLECULAR WEIGHT; NONHUMAN; PRIORITY JOURNAL; WHOLE CELL;

BORONIC ACIDS; MOLECULAR MIMICRY; PEPTIDOGLYCAN; SERINE-TYPE D-ALA-D-ALA CARBOXYPEPTIDASE;

BACILLUS SUBTILIS; BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 84859375578     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi300148v     Document Type: Article

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