Active site restructuring regulates ligand recognition in class A penicillin-binding proteins

Proceedings of the National Academy of Sciences of the United States of America

Volumn 102, Issue 3, 2005, Pages 577-582

  Macheboeuf, Pauline ^a   Di Guilmi, Anne Marie ^a   Job, Viviana ^a   Vernet, Thierry ^a   Dideberg, Otto ^a   Dessen, Andréa ^a  

^a INSTITUT DE BIOLOGIE STRUCTURALE   (France)

Author keywords

Antibiotic; cell wall; Glycosyltransferase; Transpeptidase

Indexed keywords

BETA LACTAM ANTIBIOTIC; CEFALOTIN; CEFOTAXIME; GAMMA GLUTAMYLTRANSFERASE; GLYCOSYLTRANSFERASE; NITROCEFIN; PENICILLIN BINDING PROTEIN; PENICILLIN G; PEPTIDOGLYCAN;

ACYLATION; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL CELL WALL; CELL DIVISION; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; DRUG STRUCTURE; ENZYME ACTIVE SITE; LIGAND BINDING; MUTAGENESIS; NONHUMAN; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN CROSS LINKING; SEQUENCE ALIGNMENT; STREPTOCOCCUS PNEUMONIAE;

AMINO ACID SEQUENCE; BETA-LACTAM RESISTANCE; BETA-LACTAMS; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; LIGANDS; MOLECULAR STRUCTURE; MUTATION, MISSENSE; PENICILLIN-BINDING PROTEINS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; SEQUENCE ALIGNMENT; STREPTOCOCCUS PNEUMONIAE;

BACTERIA (MICROORGANISMS); NEGIBACTERIA; STREPTOCOCCUS; STREPTOCOCCUS PNEUMONIAE;

EID: 14144256353     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0407186102     Document Type: Article

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