Toward better antibiotics: Crystallographic studies of a novel class of DD-peptidase/β-lactamase inhibitors

Biochemistry

Volumn 43, Issue 22, 2004, Pages 7046-7053

  Silvaggi, Nicholas R ^a   Kaur, Kamaljit ^b   Adediran, S A ^b   Pratt, R F ^b   Kelly, Judith A ^a  

^a UNIVERSITY OF CONNECTICUT   (United States)

^b WESLEYAN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTICS; BACTERIOLOGY; CELLS; CRYSTALLOGRAPHY; ENZYMES; PATIENT TREATMENT;

BACTERIAL INFECTIONS; ENZYME INHIBITORS;

BIOCHEMISTRY;

1 HYDROXY 4 PHENYL 2,6 DIOXAPHOSPHORINANONE(3) 1 OXIDE; 1 HYDROXY 4,5 BENZO 2,6 DIOXAPHOSPHORINANONE(3) 1 OXIDE; ANTIBIOTIC AGENT; BETA LACTAM ANTIBIOTIC; BETA LACTAMASE INHIBITOR; CARBOXYPEPTIDASE TRANSPEPTIDASE; CEPHALOSPORIN DERIVATIVE; PENICILLIN DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; DRUG DESIGN; ENTEROBACTER CLOACAE; ENZYME INHIBITION; ENZYME INHIBITOR COMPLEX; ENZYME KINETICS; ENZYME PHOSPHORYLATION; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL; STEREOCHEMISTRY; STREPTOMYCES; X RAY CRYSTALLOGRAPHY;

ACYLATION; ANTI-BACTERIAL AGENTS; BETA-LACTAMASES; CARBOXYPEPTIDASES; CRYSTALLOGRAPHY, X-RAY; ENZYME INHIBITORS; HYDROCARBONS, ACYCLIC; LIGANDS; MODELS, MOLECULAR; PHOSPHORYLATION; PROTEIN CONFORMATION; SERINE-TYPE D-ALA-D-ALA CARBOXYPEPTIDASE; STREPTOMYCES;

BACTERIA (MICROORGANISMS); ENTEROBACTER; ENTEROBACTER CLOACAE; STREPTOMYCES;

EID: 2642588180     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi049612c     Document Type: Article

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