메뉴 건너뛰기




Volumn 7, Issue 3, 2012, Pages

Characterization of an Nmr homolog that modulates gata factor-mediated nitrogen metabolite repression in cryptococcus neoformans

Author keywords

[No Author keywords available]

Indexed keywords

CARBOXY TERMINAL TELOPEPTIDE; FUNGAL PROTEIN; NITROGEN; NITROGEN METABOLIC REGULATION PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR GATA; TRANSCRIPTION FACTOR GATA 1; TRANSCRIPTION FACTOR TAR1; UNCLASSIFIED DRUG; GAT1 PROTEIN, CRYPTOCOCCUS NEOFORMANS;

EID: 84859085375     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0032585     Document Type: Article
Times cited : (12)

References (94)
  • 1
    • 68249109295 scopus 로고    scopus 로고
    • Fungal Molecular Pathogenesis: What Can It Do and Why Do We Need It?
    • In: Heitman J, Filler SG, Edwards JE, Mitchell AP, editors, Washington, DC, ASM Press
    • Perfect JR, Casadevall A, (2006) Fungal Molecular Pathogenesis: What Can It Do and Why Do We Need It? In: Heitman J, Filler SG, Edwards JE, Mitchell AP, editors. Molecular Principles of Fungal Pathogenesis Washington, DC ASM Press pp. 3-11.
    • (2006) Molecular Principles of Fungal Pathogenesis , pp. 3-11
    • Perfect, J.R.1    Casadevall, A.2
  • 2
    • 0025082117 scopus 로고
    • nit-2, the major positive-acting nitrogen regulatory gene of Neurospora crassa, encodes a sequence-specific DNA-binding protein
    • Fu YH, Marzluf GA, (1990) nit-2, the major positive-acting nitrogen regulatory gene of Neurospora crassa, encodes a sequence-specific DNA-binding protein. Proc Natl Acad Sci U S A 87: 5331-5335.
    • (1990) Proc Natl Acad Sci U S A , vol.87 , pp. 5331-5335
    • Fu, Y.H.1    Marzluf, G.A.2
  • 3
    • 0025220463 scopus 로고
    • The regulatory gene areA mediating nitrogen metabolite repression in Aspergillus nidulans. Mutations affecting specificity of gene activation alter a loop residue of a putative zinc finger
    • Kudla B, Caddick MX, Langdon T, Martinez-Rossi NM, Bennett CF, et al. (1990) The regulatory gene areA mediating nitrogen metabolite repression in Aspergillus nidulans. Mutations affecting specificity of gene activation alter a loop residue of a putative zinc finger. EMBO J 9: 1355-1364.
    • (1990) EMBO J , vol.9 , pp. 1355-1364
    • Kudla, B.1    Caddick, M.X.2    Langdon, T.3    Martinez-Rossi, N.M.4    Bennett, C.F.5
  • 4
    • 0025999296 scopus 로고
    • Sequence and expression of GLN3, a positive nitrogen regulatory gene of Saccharomyces cerevisiae encoding a protein with a putative zinc finger DNA-binding domain
    • Minehart PL, Magasanik B, (1991) Sequence and expression of GLN3, a positive nitrogen regulatory gene of Saccharomyces cerevisiae encoding a protein with a putative zinc finger DNA-binding domain. Mol Cell Biol 11: 6216-6228.
    • (1991) Mol Cell Biol , vol.11 , pp. 6216-6228
    • Minehart, P.L.1    Magasanik, B.2
  • 5
    • 0021706678 scopus 로고
    • Regulation of glutamine-repressible gene products by the GLN3 function in Saccharomyces cerevisiae
    • Mitchell AP, Magasanik B, (1984) Regulation of glutamine-repressible gene products by the GLN3 function in Saccharomyces cerevisiae. Mol Cell Biol 4: 2758-2766.
    • (1984) Mol Cell Biol , vol.4 , pp. 2758-2766
    • Mitchell, A.P.1    Magasanik, B.2
  • 6
    • 0021744939 scopus 로고
    • Three regulatory systems control production of glutamine synthetase in Saccharomyces cerevisiae
    • Mitchell AP, Magasanik B, (1984) Three regulatory systems control production of glutamine synthetase in Saccharomyces cerevisiae. Mol Cell Biol 4: 2767-2773.
    • (1984) Mol Cell Biol , vol.4 , pp. 2767-2773
    • Mitchell, A.P.1    Magasanik, B.2
  • 7
    • 0028832649 scopus 로고
    • Role of the GATA factors Gln3p and Nil1p of Saccharomyces cerevisiae in the expression of nitrogen-regulated genes
    • Stanbrough M, Rowen DW, Magasanik B, (1995) Role of the GATA factors Gln3p and Nil1p of Saccharomyces cerevisiae in the expression of nitrogen-regulated genes. Proc Natl Acad Sci U S A 92: 9450-9454.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 9450-9454
    • Stanbrough, M.1    Rowen, D.W.2    Magasanik, B.3
  • 8
    • 0022873831 scopus 로고
    • Molecular cloning of nit-2, a regulatory gene required for nitrogen metabolite repression in Neurospora crassa
    • Stewart V, Vollmer SJ, (1986) Molecular cloning of nit-2, a regulatory gene required for nitrogen metabolite repression in Neurospora crassa. Gene 46: 291-295.
    • (1986) Gene , vol.46 , pp. 291-295
    • Stewart, V.1    Vollmer, S.J.2
  • 9
    • 0015840490 scopus 로고
    • Nitrogen metabolite repression in Aspergillus nidulans
    • Arst HN Jr, Cove DJ, (1973) Nitrogen metabolite repression in Aspergillus nidulans. Mol Gen Genet 126: 111-141.
    • (1973) Mol Gen Genet , vol.126 , pp. 111-141
    • Arst Jr., H.N.1    Cove, D.J.2
  • 10
    • 0037094434 scopus 로고    scopus 로고
    • Nitrogen regulation in Saccharomyces cerevisiae
    • Magasanik B, Kaiser CA, (2002) Nitrogen regulation in Saccharomyces cerevisiae. Gene 290: 1-18.
    • (2002) Gene , vol.290 , pp. 1-18
    • Magasanik, B.1    Kaiser, C.A.2
  • 11
    • 0030794656 scopus 로고    scopus 로고
    • Genetic regulation of nitrogen metabolism in the fungi
    • Marzluf GA, (1997) Genetic regulation of nitrogen metabolism in the fungi. Microbiol Mol Biol Rev 61: 17-32.
    • (1997) Microbiol Mol Biol Rev , vol.61 , pp. 17-32
    • Marzluf, G.A.1
  • 12
    • 46949091825 scopus 로고    scopus 로고
    • Recent advances in nitrogen regulation: a comparison between Saccharomyces cerevisiae and filamentous fungi
    • Wong KH, Hynes MJ, Davis MA, (2008) Recent advances in nitrogen regulation: a comparison between Saccharomyces cerevisiae and filamentous fungi. Eukaryot Cell 7: 917-925.
    • (2008) Eukaryot Cell , vol.7 , pp. 917-925
    • Wong, K.H.1    Hynes, M.J.2    Davis, M.A.3
  • 13
    • 0030028431 scopus 로고    scopus 로고
    • Gat1p, a GATA family protein whose production is sensitive to nitrogen catabolite repression, participates in transcriptional activation of nitrogen-catabolic genes in Saccharomyces cerevisiae
    • Coffman JA, Rai R, Cunningham T, Svetlov V, Cooper TG, (1996) Gat1p, a GATA family protein whose production is sensitive to nitrogen catabolite repression, participates in transcriptional activation of nitrogen-catabolic genes in Saccharomyces cerevisiae. Mol Cell Biol 16: 847-858.
    • (1996) Mol Cell Biol , vol.16 , pp. 847-858
    • Coffman, J.A.1    Rai, R.2    Cunningham, T.3    Svetlov, V.4    Cooper, T.G.5
  • 14
    • 0033540030 scopus 로고    scopus 로고
    • The TOR signalling pathway controls nuclear localization of nutrient-regulated transcription factors
    • Beck T, Hall MN, (1999) The TOR signalling pathway controls nuclear localization of nutrient-regulated transcription factors. Nature 402: 689-692.
    • (1999) Nature , vol.402 , pp. 689-692
    • Beck, T.1    Hall, M.N.2
  • 15
    • 0034680772 scopus 로고    scopus 로고
    • Tripartite regulation of Gln3p by TOR, Ure2p, and phosphatases
    • Bertram PG, Choi JH, Carvalho J, Ai W, Zeng C, et al. (2000) Tripartite regulation of Gln3p by TOR, Ure2p, and phosphatases. J Biol Chem 275: 35727-35733.
    • (2000) J Biol Chem , vol.275 , pp. 35727-35733
    • Bertram, P.G.1    Choi, J.H.2    Carvalho, J.3    Ai, W.4    Zeng, C.5
  • 16
    • 0036024577 scopus 로고    scopus 로고
    • Transmitting the signal of excess nitrogen in Saccharomyces cerevisiae from the Tor proteins to the GATA factors: connecting the dots
    • Cooper TG, (2002) Transmitting the signal of excess nitrogen in Saccharomyces cerevisiae from the Tor proteins to the GATA factors: connecting the dots. FEMS Microbiol Rev 26: 223-238.
    • (2002) FEMS Microbiol Rev , vol.26 , pp. 223-238
    • Cooper, T.G.1
  • 17
    • 0034640545 scopus 로고    scopus 로고
    • Nitrogen catabolite repression of DAL80 expression depends on the relative levels of Gat1p and Ure2p production in Saccharomyces cerevisiae
    • Cunningham TS, Andhare R, Cooper TG, (2000) Nitrogen catabolite repression of DAL80 expression depends on the relative levels of Gat1p and Ure2p production in Saccharomyces cerevisiae. J Biol Chem 275: 14408-14414.
    • (2000) J Biol Chem , vol.275 , pp. 14408-14414
    • Cunningham, T.S.1    Andhare, R.2    Cooper, T.G.3
  • 18
    • 0030691785 scopus 로고    scopus 로고
    • Two distinct protein-protein interactions between the NIT2 and NMR regulatory proteins are required to establish nitrogen metabolite repression in Neurospora crassa
    • Pan H, Feng B, Marzluf GA, (1997) Two distinct protein-protein interactions between the NIT2 and NMR regulatory proteins are required to establish nitrogen metabolite repression in Neurospora crassa. Mol Microbiol 26: 721-729.
    • (1997) Mol Microbiol , vol.26 , pp. 721-729
    • Pan, H.1    Feng, B.2    Marzluf, G.A.3
  • 19
    • 0019271966 scopus 로고
    • Physiological characterization of a Neurospora crassa mutant with impaired regulation of nitrate reductase
    • Premakumar R, Sorger GJ, Gooden D, (1980) Physiological characterization of a Neurospora crassa mutant with impaired regulation of nitrate reductase. J Bacteriol 144: 542-551.
    • (1980) J Bacteriol , vol.144 , pp. 542-551
    • Premakumar, R.1    Sorger, G.J.2    Gooden, D.3
  • 20
    • 0029019941 scopus 로고
    • The negative-acting NMR regulatory protein of Neurospora crassa binds to and inhibits the DNA-binding activity of the positive-acting nitrogen regulatory protein NIT2
    • Xiao X, Fu YH, Marzluf GA, (1995) The negative-acting NMR regulatory protein of Neurospora crassa binds to and inhibits the DNA-binding activity of the positive-acting nitrogen regulatory protein NIT2. Biochemistry 34: 8861-8868.
    • (1995) Biochemistry , vol.34 , pp. 8861-8868
    • Xiao, X.1    Fu, Y.H.2    Marzluf, G.A.3
  • 21
    • 0031896503 scopus 로고    scopus 로고
    • Characterization of the Aspergillus nidulans nmrA gene involved in nitrogen metabolite repression
    • Andrianopoulos A, Kourambas S, Sharp JA, Davis MA, Hynes MJ, (1998) Characterization of the Aspergillus nidulans nmrA gene involved in nitrogen metabolite repression. J Bacteriol 180: 1973-1977.
    • (1998) J Bacteriol , vol.180 , pp. 1973-1977
    • Andrianopoulos, A.1    Kourambas, S.2    Sharp, J.A.3    Davis, M.A.4    Hynes, M.J.5
  • 22
    • 0042858150 scopus 로고    scopus 로고
    • The negative transcriptional regulator NmrA discriminates between oxidized and reduced dinucleotides
    • Lamb HK, Leslie K, Dodds AL, Nutley M, Cooper A, et al. (2003) The negative transcriptional regulator NmrA discriminates between oxidized and reduced dinucleotides. J Biol Chem 278: 32107-32114.
    • (2003) J Biol Chem , vol.278 , pp. 32107-32114
    • Lamb, H.K.1    Leslie, K.2    Dodds, A.L.3    Nutley, M.4    Cooper, A.5
  • 23
    • 0029950890 scopus 로고    scopus 로고
    • Nitrogen metabolite signalling involves the C-terminus and the GATA domain of the Aspergillus transcription factor AREA and the 3′ untranslated region of its mRNA
    • Platt A, Langdon T, Arst HN Jr, Kirk D, Tollervey D, et al. (1996) Nitrogen metabolite signalling involves the C-terminus and the GATA domain of the Aspergillus transcription factor AREA and the 3′ untranslated region of its mRNA. EMBO J 15: 2791-2801.
    • (1996) EMBO J , vol.15 , pp. 2791-2801
    • Platt, A.1    Langdon, T.2    Arst Jr., H.N.3    Kirk, D.4    Tollervey, D.5
  • 24
    • 0028882956 scopus 로고
    • Mutational analysis reveals dispensability of the N-terminal region of the Aspergillus transcription factor mediating nitrogen metabolite repression
    • Langdon T, Sheerins A, Ravagnani A, Gielkens M, Caddick MX, et al. (1995) Mutational analysis reveals dispensability of the N-terminal region of the Aspergillus transcription factor mediating nitrogen metabolite repression. Mol Microbiol 17: 877-888.
    • (1995) Mol Microbiol , vol.17 , pp. 877-888
    • Langdon, T.1    Sheerins, A.2    Ravagnani, A.3    Gielkens, M.4    Caddick, M.X.5
  • 25
    • 0033813131 scopus 로고    scopus 로고
    • A defined sequence within the 3′ UTR of the areA transcript is sufficient to mediate nitrogen metabolite signalling via accelerated deadenylation
    • Morozov IY, Martinez MG, Jones MG, Caddick MX, (2000) A defined sequence within the 3′ UTR of the areA transcript is sufficient to mediate nitrogen metabolite signalling via accelerated deadenylation. Mol Microbiol 37: 1248-1257.
    • (2000) Mol Microbiol , vol.37 , pp. 1248-1257
    • Morozov, I.Y.1    Martinez, M.G.2    Jones, M.G.3    Caddick, M.X.4
  • 26
    • 17644386151 scopus 로고    scopus 로고
    • The Mep2p ammonium permease controls nitrogen starvation-induced filamentous growth in Candida albicans
    • Biswas K, Morschhauser J, (2005) The Mep2p ammonium permease controls nitrogen starvation-induced filamentous growth in Candida albicans. Mol Microbiol 56: 649-669.
    • (2005) Mol Microbiol , vol.56 , pp. 649-669
    • Biswas, K.1    Morschhauser, J.2
  • 27
    • 34249690692 scopus 로고    scopus 로고
    • Control of ammonium permease expression and filamentous growth by the GATA transcription factors GLN3 and GAT1 in Candida albicans
    • Dabas N, Morschhauser J, (2007) Control of ammonium permease expression and filamentous growth by the GATA transcription factors GLN3 and GAT1 in Candida albicans. Eukaryot Cell 6: 875-888.
    • (2007) Eukaryot Cell , vol.6 , pp. 875-888
    • Dabas, N.1    Morschhauser, J.2
  • 28
    • 39749203509 scopus 로고    scopus 로고
    • GLN3 encodes a global regulator of nitrogen metabolism and virulence of C. albicans
    • Liao WL, Ramon AM, Fonzi WA, (2008) GLN3 encodes a global regulator of nitrogen metabolism and virulence of C. albicans. Fungal Genet Biol 45: 514-526.
    • (2008) Fungal Genet Biol , vol.45 , pp. 514-526
    • Liao, W.L.1    Ramon, A.M.2    Fonzi, W.A.3
  • 29
    • 0242606099 scopus 로고    scopus 로고
    • Nitrogen metabolism and virulence of Candida albicans require the GATA-type transcriptional activator encoded by GAT1
    • Limjindaporn T, Khalaf RA, Fonzi WA, (2003) Nitrogen metabolism and virulence of Candida albicans require the GATA-type transcriptional activator encoded by GAT1. Mol Microbiol 50: 993-1004.
    • (2003) Mol Microbiol , vol.50 , pp. 993-1004
    • Limjindaporn, T.1    Khalaf, R.A.2    Fonzi, W.A.3
  • 30
    • 0031818693 scopus 로고    scopus 로고
    • The role of the Aspergillus fumigatus areA gene in invasive pulmonary aspergillosis
    • Hensel M, Arst HN Jr, Aufauvre-Brown A, Holden DW, (1998) The role of the Aspergillus fumigatus areA gene in invasive pulmonary aspergillosis. Mol Gen Genet 258: 553-557.
    • (1998) Mol Gen Genet , vol.258 , pp. 553-557
    • Hensel, M.1    Arst Jr., H.N.2    Aufauvre-Brown, A.3    Holden, D.W.4
  • 31
    • 84859048414 scopus 로고    scopus 로고
    • AreA controls nitrogen source utilisation during both growth programs of the dimorphic fungus Penicillium marneffei
    • In press
    • Bugeja HE, Hynes MJ, Andrianopoulos A, (2011) AreA controls nitrogen source utilisation during both growth programs of the dimorphic fungus Penicillium marneffei. Fungal Biol In press.
    • (2011) Fungal Biol
    • Bugeja, H.E.1    Hynes, M.J.2    Andrianopoulos, A.3
  • 32
    • 0002427193 scopus 로고
    • Cryptococcosis
    • In: Kwon-Chung KJ, Bennett JE, editors, Philadelphia, P.A., Lea & Febiger,2nd Ed
    • Kwon-Chung KJ, Bennett JE, (1992) Cryptococcosis. In: Kwon-Chung KJ, Bennett JE, editors. Medical mycology. 2nd ed Philadelphia, P.A. Lea & Febiger pp. 397-446.
    • (1992) Medical Mycology , pp. 397-446
    • Kwon-Chung, K.J.1    Bennett, J.E.2
  • 33
    • 78649920352 scopus 로고    scopus 로고
    • The GATA-type transcriptional activator Gat1 regulates nitrogen uptake and metabolism in the human pathogen Cryptococcus neoformans
    • Kmetzsch L, Staats CC, Simon E, Fonseca FL, Oliveira DL, et al. (2011) The GATA-type transcriptional activator Gat1 regulates nitrogen uptake and metabolism in the human pathogen Cryptococcus neoformans. Fungal Genet Biol 48: 192-199.
    • (2011) Fungal Genet Biol , vol.48 , pp. 192-199
    • Kmetzsch, L.1    Staats, C.C.2    Simon, E.3    Fonseca, F.L.4    Oliveira, D.L.5
  • 34
    • 79958242411 scopus 로고    scopus 로고
    • Nitrogen Metabolite Repression of Metabolism and Virulence in the Human Fungal Pathogen Cryptococcus neoformans
    • Lee IR, Chow EW, Morrow CA, Djordjevic JT, Fraser JA, (2011) Nitrogen Metabolite Repression of Metabolism and Virulence in the Human Fungal Pathogen Cryptococcus neoformans. Genetics 188: 309-323.
    • (2011) Genetics , vol.188 , pp. 309-323
    • Lee, I.R.1    Chow, E.W.2    Morrow, C.A.3    Djordjevic, J.T.4    Fraser, J.A.5
  • 35
    • 79955932714 scopus 로고    scopus 로고
    • Prion-forming ability of Ure2 of yeasts is not evolutionarily conserved
    • Edskes HK, Engel A, McCann LM, Brachmann A, Tsai HF, et al. (2011) Prion-forming ability of Ure2 of yeasts is not evolutionarily conserved. Genetics 188: 81-90.
    • (2011) Genetics , vol.188 , pp. 81-90
    • Edskes, H.K.1    Engel, A.2    McCann, L.M.3    Brachmann, A.4    Tsai, H.F.5
  • 36
    • 0037058949 scopus 로고    scopus 로고
    • Conservation of a portion of the S. cerevisiae Ure2p prion domain that interacts with the full-length protein
    • Edskes HK, Wickner RB, (2002) Conservation of a portion of the S. cerevisiae Ure2p prion domain that interacts with the full-length protein. Proc Natl Acad Sci U S A 99 (Suppl 4): 16384-16391.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , Issue.SUPPL. 4 , pp. 16384-16391
    • Edskes, H.K.1    Wickner, R.B.2
  • 37
    • 34748923601 scopus 로고    scopus 로고
    • Transcriptional control of nmrA by the bZIP transcription factor MeaB reveals a new level of nitrogen regulation in Aspergillus nidulans
    • Wong KH, Hynes MJ, Todd RB, Davis MA, (2007) Transcriptional control of nmrA by the bZIP transcription factor MeaB reveals a new level of nitrogen regulation in Aspergillus nidulans. Mol Microbiol 66: 534-551.
    • (2007) Mol Microbiol , vol.66 , pp. 534-551
    • Wong, K.H.1    Hynes, M.J.2    Todd, R.B.3    Davis, M.A.4
  • 38
    • 70350520499 scopus 로고    scopus 로고
    • Negative roles of a novel nitrogen metabolite repression-related gene, TAR1, in laccase production and nitrate utilization by the basidiomycete Cryptococcus neoformans
    • Jiang N, Xiao D, Zhang D, Sun N, Yan B, et al. (2009) Negative roles of a novel nitrogen metabolite repression-related gene, TAR1, in laccase production and nitrate utilization by the basidiomycete Cryptococcus neoformans. Appl Environ Microbiol 75: 6777-6782.
    • (2009) Appl Environ Microbiol , vol.75 , pp. 6777-6782
    • Jiang, N.1    Xiao, D.2    Zhang, D.3    Sun, N.4    Yan, B.5
  • 39
    • 0036810314 scopus 로고    scopus 로고
    • Transcription corepressor CtBP is an NAD(+)-regulated dehydrogenase
    • Kumar V, Carlson JE, Ohgi KA, Edwards TA, Rose DW, et al. (2002) Transcription corepressor CtBP is an NAD(+)-regulated dehydrogenase. Mol Cell 10: 857-869.
    • (2002) Mol Cell , vol.10 , pp. 857-869
    • Kumar, V.1    Carlson, J.E.2    Ohgi, K.A.3    Edwards, T.A.4    Rose, D.W.5
  • 40
    • 9344220480 scopus 로고    scopus 로고
    • Modulation of the ligand binding properties of the transcription repressor NmrA by GATA-containing DNA and site-directed mutagenesis
    • Lamb HK, Ren J, Park A, Johnson C, Leslie K, et al. (2004) Modulation of the ligand binding properties of the transcription repressor NmrA by GATA-containing DNA and site-directed mutagenesis. Protein Sci 13: 3127-3138.
    • (2004) Protein Sci , vol.13 , pp. 3127-3138
    • Lamb, H.K.1    Ren, J.2    Park, A.3    Johnson, C.4    Leslie, K.5
  • 41
    • 0035803486 scopus 로고    scopus 로고
    • The structure of the negative transcriptional regulator NmrA reveals a structural superfamily which includes the short-chain dehydrogenase/reductases
    • Stammers DK, Ren J, Leslie K, Nichols CE, Lamb HK, et al. (2001) The structure of the negative transcriptional regulator NmrA reveals a structural superfamily which includes the short-chain dehydrogenase/reductases. EMBO J 20: 6619-6626.
    • (2001) EMBO J , vol.20 , pp. 6619-6626
    • Stammers, D.K.1    Ren, J.2    Leslie, K.3    Nichols, C.E.4    Lamb, H.K.5
  • 42
    • 33847291392 scopus 로고    scopus 로고
    • Understanding a transcriptional paradigm at the molecular level. The structure of yeast Gal80p
    • Thoden JB, Sellick CA, Reece RJ, Holden HM, (2007) Understanding a transcriptional paradigm at the molecular level. The structure of yeast Gal80p. J Biol Chem 282: 1534-1538.
    • (2007) J Biol Chem , vol.282 , pp. 1534-1538
    • Thoden, J.B.1    Sellick, C.A.2    Reece, R.J.3    Holden, H.M.4
  • 43
    • 0025339828 scopus 로고
    • Nucleotide sequence and analysis of NMR, a negative-acting regulatory gene in the nitrogen circuit of Neurospora crassa
    • Young JL, Jarai G, Fu YH, Marzluf GA, (1990) Nucleotide sequence and analysis of NMR, a negative-acting regulatory gene in the nitrogen circuit of Neurospora crassa. Mol Gen Genet 222: 120-128.
    • (1990) Mol Gen Genet , vol.222 , pp. 120-128
    • Young, J.L.1    Jarai, G.2    Fu, Y.H.3    Marzluf, G.A.4
  • 44
    • 0035047590 scopus 로고    scopus 로고
    • Cyclic AMP-dependent protein kinase controls virulence of the fungal pathogen Cryptococcus neoformans
    • D'Souza CA, Alspaugh JA, Yue C, Harashima T, Cox GM, et al. (2001) Cyclic AMP-dependent protein kinase controls virulence of the fungal pathogen Cryptococcus neoformans. Mol Cell Biol 21: 3179-3191.
    • (2001) Mol Cell Biol , vol.21 , pp. 3179-3191
    • D'Souza, C.A.1    Alspaugh, J.A.2    Yue, C.3    Harashima, T.4    Cox, G.M.5
  • 45
    • 13744252513 scopus 로고    scopus 로고
    • Transcriptional network of multiple capsule and melanin genes governed by the Cryptococcus neoformans cyclic AMP cascade
    • Pukkila-Worley R, Gerrald QD, Kraus PR, Boily MJ, Davis MJ, et al. (2005) Transcriptional network of multiple capsule and melanin genes governed by the Cryptococcus neoformans cyclic AMP cascade. Eukaryot Cell 4: 190-201.
    • (2005) Eukaryot Cell , vol.4 , pp. 190-201
    • Pukkila-Worley, R.1    Gerrald, Q.D.2    Kraus, P.R.3    Boily, M.J.4    Davis, M.J.5
  • 46
    • 0028069606 scopus 로고
    • Biochemical and molecular characterization of the diphenol oxidase of Cryptococcus neoformans: identification as a laccase
    • Williamson PR, (1994) Biochemical and molecular characterization of the diphenol oxidase of Cryptococcus neoformans: identification as a laccase. J Bacteriol 176: 656-664.
    • (1994) J Bacteriol , vol.176 , pp. 656-664
    • Williamson, P.R.1
  • 47
    • 34250847645 scopus 로고    scopus 로고
    • Cryptococcus neoformans mates on pigeon guano: implications for the realized ecological niche and globalization
    • Nielsen K, De Obaldia AL, Heitman J, (2007) Cryptococcus neoformans mates on pigeon guano: implications for the realized ecological niche and globalization. Eukaryot Cell 6: 949-959.
    • (2007) Eukaryot Cell , vol.6 , pp. 949-959
    • Nielsen, K.1    de Obaldia, A.L.2    Heitman, J.3
  • 49
    • 0016063911 scopus 로고
    • The genetics of Caenorhabditis elegans
    • Brenner S, (1974) The genetics of Caenorhabditis elegans. Genetics 77: 71-94.
    • (1974) Genetics , vol.77 , pp. 71-94
    • Brenner, S.1
  • 51
    • 0027467912 scopus 로고
    • Oxygen-dependent perturbation of life span and aging rate in the nematode
    • Honda S, Ishii N, Suzuki K, Matsuo M, (1993) Oxygen-dependent perturbation of life span and aging rate in the nematode. J Gerontol 48: B57-61.
    • (1993) J Gerontol , vol.48
    • Honda, S.1    Ishii, N.2    Suzuki, K.3    Matsuo, M.4
  • 53
    • 0027968068 scopus 로고
    • CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice
    • Thompson JD, Higgins DG, Gibson TJ, (1994) CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res 22: 4673-4680.
    • (1994) Nucleic Acids Res , vol.22 , pp. 4673-4680
    • Thompson, J.D.1    Higgins, D.G.2    Gibson, T.J.3
  • 54
    • 0036667448 scopus 로고    scopus 로고
    • A PCR-based strategy to generate integrative targeting alleles with large regions of homology
    • Davidson RC, Blankenship JR, Kraus PR, de Jesus Berrios M, Hull CM, et al. (2002) A PCR-based strategy to generate integrative targeting alleles with large regions of homology. Microbiology 148: 2607-2615.
    • (2002) Microbiology , vol.148 , pp. 2607-2615
    • Davidson, R.C.1    Blankenship, J.R.2    Kraus, P.R.3    de Jesus Berrios, M.4    Hull, C.M.5
  • 55
    • 0142216112 scopus 로고    scopus 로고
    • Recapitulation of the sexual cycle of the primary fungal pathogen Cryptococcus neoformans var. gattii: implications for an outbreak on Vancouver Island, Canada
    • Fraser JA, Subaran RL, Nichols CB, Heitman J, (2003) Recapitulation of the sexual cycle of the primary fungal pathogen Cryptococcus neoformans var. gattii: implications for an outbreak on Vancouver Island, Canada. Eukaryot Cell 2: 1036-1045.
    • (2003) Eukaryot Cell , vol.2 , pp. 1036-1045
    • Fraser, J.A.1    Subaran, R.L.2    Nichols, C.B.3    Heitman, J.4
  • 56
    • 34248670011 scopus 로고    scopus 로고
    • Southern blotting
    • Southern E, (2006) Southern blotting. Nat Protoc 1: 518-525.
    • (2006) Nat Protoc , vol.1 , pp. 518-525
    • Southern, E.1
  • 57
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
    • Livak KJ, Schmittgen TD, (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25: 402-408.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 58
    • 0030455820 scopus 로고    scopus 로고
    • Genomic libraries and a host strain designed for highly efficient two-hybrid selection in yeast
    • James P, Halladay J, Craig EA, (1996) Genomic libraries and a host strain designed for highly efficient two-hybrid selection in yeast. Genetics 144: 1425-1436.
    • (1996) Genetics , vol.144 , pp. 1425-1436
    • James, P.1    Halladay, J.2    Craig, E.A.3
  • 59
    • 34347206860 scopus 로고    scopus 로고
    • High-efficiency yeast transformation using the LiAc/SS carrier DNA/PEG method
    • Gietz RD, Schiestl RH, (2007) High-efficiency yeast transformation using the LiAc/SS carrier DNA/PEG method. Nat Protoc 2: 31-34.
    • (2007) Nat Protoc , vol.2 , pp. 31-34
    • Gietz, R.D.1    Schiestl, R.H.2
  • 60
    • 0028597938 scopus 로고
    • Immunophilins interact with calcineurin in the absence of exogenous immunosuppressive ligands
    • Cardenas ME, Hemenway C, Muir RS, Ye R, Fiorentino D, et al. (1994) Immunophilins interact with calcineurin in the absence of exogenous immunosuppressive ligands. EMBO J 13: 5944-5957.
    • (1994) EMBO J , vol.13 , pp. 5944-5957
    • Cardenas, M.E.1    Hemenway, C.2    Muir, R.S.3    Ye, R.4    Fiorentino, D.5
  • 63
    • 0016593991 scopus 로고
    • Comparison of four methods for determining nitrate utilization by cryptococci
    • Rhodes JC, Roberts GD, (1975) Comparison of four methods for determining nitrate utilization by cryptococci. J Clin Microbiol 1: 9-10.
    • (1975) J Clin Microbiol , vol.1 , pp. 9-10
    • Rhodes, J.C.1    Roberts, G.D.2
  • 64
    • 41549141861 scopus 로고    scopus 로고
    • Horizontal transfer of a nitrate assimilation gene cluster and ecological transitions in fungi: a phylogenetic study
    • Slot JC, Hibbett DS, (2007) Horizontal transfer of a nitrate assimilation gene cluster and ecological transitions in fungi: a phylogenetic study. PLoS One 2: e1097.
    • (2007) PLoS One , vol.2
    • Slot, J.C.1    Hibbett, D.S.2
  • 65
    • 0019973878 scopus 로고
    • Urea and thiourea transport in Aspergillus nidulans
    • Pateman JA, Dunn E, Mackay EM, (1982) Urea and thiourea transport in Aspergillus nidulans. Biochem Genet 20: 777-790.
    • (1982) Biochem Genet , vol.20 , pp. 777-790
    • Pateman, J.A.1    Dunn, E.2    Mackay, E.M.3
  • 66
    • 0035029546 scopus 로고    scopus 로고
    • The Aspergillus nidulans GATA transcription factor gene areB encodes at least three proteins and features three classes of mutation
    • Conlon H, Zadra I, Haas H, Arst HN Jr, Jones MG, et al. (2001) The Aspergillus nidulans GATA transcription factor gene areB encodes at least three proteins and features three classes of mutation. Mol Microbiol 40: 361-375.
    • (2001) Mol Microbiol , vol.40 , pp. 361-375
    • Conlon, H.1    Zadra, I.2    Haas, H.3    Arst Jr., H.N.4    Jones, M.G.5
  • 67
    • 84859078054 scopus 로고    scopus 로고
    • GATA-factor-mediated transcription and Tor1/2 in Saccharomyces cerevisiae from a physiological perspective
    • In: Brambl R, Marzluf GA, editors, Berlin, Germany, Springer Verlag,2 Ed
    • Copper TG, (2004) GATA-factor-mediated transcription and Tor1/2 in Saccharomyces cerevisiae from a physiological perspective. In: Brambl R, Marzluf GA, editors. Biochemistry and molecular biology The Mycota III. 2 ed Berlin, Germany Springer Verlag pp. 81-119.
    • (2004) Biochemistry and Molecular Biology The Mycota III , pp. 81-119
    • Copper, T.G.1
  • 68
    • 79952643476 scopus 로고    scopus 로고
    • A major role for capsule-independent phagocytosis-inhibitory mechanisms in mammalian infection by Cryptococcus neoformans
    • Chun CD, Brown JC, Madhani HD, (2011) A major role for capsule-independent phagocytosis-inhibitory mechanisms in mammalian infection by Cryptococcus neoformans. Cell Host Microbe 9: 243-251.
    • (2011) Cell Host Microbe , vol.9 , pp. 243-251
    • Chun, C.D.1    Brown, J.C.2    Madhani, H.D.3
  • 70
    • 33845493893 scopus 로고    scopus 로고
    • Iron regulation of the major virulence factors in the AIDS-associated pathogen Cryptococcus neoformans
    • Jung WH, Sham A, White R, Kronstad JW, (2006) Iron regulation of the major virulence factors in the AIDS-associated pathogen Cryptococcus neoformans. PLoS Biol 4: e410.
    • (2006) PLoS Biol , vol.4
    • Jung, W.H.1    Sham, A.2    White, R.3    Kronstad, J.W.4
  • 71
    • 52949114243 scopus 로고    scopus 로고
    • Systematic genetic analysis of virulence in the human fungal pathogen Cryptococcus neoformans
    • Liu OW, Chun CD, Chow ED, Chen C, Madhani HD, et al. (2008) Systematic genetic analysis of virulence in the human fungal pathogen Cryptococcus neoformans. Cell 135: 174-188.
    • (2008) Cell , vol.135 , pp. 174-188
    • Liu, O.W.1    Chun, C.D.2    Chow, E.D.3    Chen, C.4    Madhani, H.D.5
  • 72
    • 0028919202 scopus 로고
    • Molecular cloning and analysis of nre, the major nitrogen regulatory gene of Penicillium chrysogenum
    • Haas H, Bauer B, Redl B, Stoffler G, Marzluf GA, (1995) Molecular cloning and analysis of nre, the major nitrogen regulatory gene of Penicillium chrysogenum. Curr Genet 27: 150-158.
    • (1995) Curr Genet , vol.27 , pp. 150-158
    • Haas, H.1    Bauer, B.2    Redl, B.3    Stoffler, G.4    Marzluf, G.A.5
  • 73
    • 34547404300 scopus 로고    scopus 로고
    • Restructuring of the dinucleotide-binding fold in an NADP(H) sensor protein
    • Zheng X, Dai X, Zhao Y, Chen Q, Lu F, et al. (2007) Restructuring of the dinucleotide-binding fold in an NADP(H) sensor protein. Proc Natl Acad Sci U S A 104: 8809-8814.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 8809-8814
    • Zheng, X.1    Dai, X.2    Zhao, Y.3    Chen, Q.4    Lu, F.5
  • 74
    • 13744260680 scopus 로고    scopus 로고
    • Distinct stress responses of two functional laccases in Cryptococcus neoformans are revealed in the absence of the thiol-specific antioxidant Tsa1
    • Missall TA, Moran JM, Corbett JA, Lodge JK, (2005) Distinct stress responses of two functional laccases in Cryptococcus neoformans are revealed in the absence of the thiol-specific antioxidant Tsa1. Eukaryot Cell 4: 202-208.
    • (2005) Eukaryot Cell , vol.4 , pp. 202-208
    • Missall, T.A.1    Moran, J.M.2    Corbett, J.A.3    Lodge, J.K.4
  • 75
    • 4644240769 scopus 로고    scopus 로고
    • Role of laccase in the biology and virulence of Cryptococcus neoformans
    • Zhu X, Williamson PR, (2004) Role of laccase in the biology and virulence of Cryptococcus neoformans. FEMS Yeast Res 5: 1-10.
    • (2004) FEMS Yeast Res , vol.5 , pp. 1-10
    • Zhu, X.1    Williamson, P.R.2
  • 76
    • 84907128142 scopus 로고
    • Temperature regulation of the cryptococcal phenoloxidase
    • Jacobson ES, Emery HS, (1991) Temperature regulation of the cryptococcal phenoloxidase. J Med Vet Mycol 29: 121-124.
    • (1991) J Med Vet Mycol , vol.29 , pp. 121-124
    • Jacobson, E.S.1    Emery, H.S.2
  • 77
    • 84860516683 scopus 로고    scopus 로고
    • A unique chromosomal rearrangement in the Cryptococcus neoformans var. grubii type strain enhances key phenotypes associated with virulence
    • In press
    • Morrow CA, Lee IR, Chow EW, Ormerod KO, Goldinger A, et al. (2012) A unique chromosomal rearrangement in the Cryptococcus neoformans var. grubii type strain enhances key phenotypes associated with virulence. mBio In press.
    • (2012) MBio
    • Morrow, C.A.1    Lee, I.R.2    Chow, E.W.3    Ormerod, K.O.4    Goldinger, A.5
  • 78
    • 4344708106 scopus 로고    scopus 로고
    • Cryptococcus neoformans capsule biosynthesis and regulation
    • Janbon G, (2004) Cryptococcus neoformans capsule biosynthesis and regulation. FEMS Yeast Res 4: 765-771.
    • (2004) FEMS Yeast Res , vol.4 , pp. 765-771
    • Janbon, G.1
  • 79
    • 0016975715 scopus 로고
    • Morphogenesis of Filobasidiella neoformans, the sexual state of Cryptococcus neoformans
    • Kwon-Chung KJ, (1976) Morphogenesis of Filobasidiella neoformans, the sexual state of Cryptococcus neoformans. Mycologia 68: 821-833.
    • (1976) Mycologia , vol.68 , pp. 821-833
    • Kwon-Chung, K.J.1
  • 80
    • 0041971075 scopus 로고    scopus 로고
    • Sexual cycle of Cryptococcus neoformans var. grubii and virulence of congenic a and alpha isolates
    • Nielsen K, Cox GM, Wang P, Toffaletti DL, Perfect JR, et al. (2003) Sexual cycle of Cryptococcus neoformans var. grubii and virulence of congenic a and alpha isolates. Infect Immun 71: 4831-4841.
    • (2003) Infect Immun , vol.71 , pp. 4831-4841
    • Nielsen, K.1    Cox, G.M.2    Wang, P.3    Toffaletti, D.L.4    Perfect, J.R.5
  • 81
    • 41449094147 scopus 로고    scopus 로고
    • Amt2 permease is required to induce ammonium-responsive invasive growth and mating in Cryptococcus neoformans
    • Rutherford JC, Lin X, Nielsen K, Heitman J, (2008) Amt2 permease is required to induce ammonium-responsive invasive growth and mating in Cryptococcus neoformans. Eukaryot Cell 7: 237-246.
    • (2008) Eukaryot Cell , vol.7 , pp. 237-246
    • Rutherford, J.C.1    Lin, X.2    Nielsen, K.3    Heitman, J.4
  • 82
    • 0035152031 scopus 로고    scopus 로고
    • The formamidase gene of Aspergillus nidulans: regulation by nitrogen metabolite repression and transcriptional interference by an overlapping upstream gene
    • Fraser JA, Davis MA, Hynes MJ, (2001) The formamidase gene of Aspergillus nidulans: regulation by nitrogen metabolite repression and transcriptional interference by an overlapping upstream gene. Genetics 157: 119-131.
    • (2001) Genetics , vol.157 , pp. 119-131
    • Fraser, J.A.1    Davis, M.A.2    Hynes, M.J.3
  • 83
    • 0036275142 scopus 로고    scopus 로고
    • A gene from Aspergillus nidulans with similarity to URE2 of Saccharomyces cerevisiae encodes a glutathione S-transferase which contributes to heavy metal and xenobiotic resistance
    • Fraser JA, Davis MA, Hynes MJ, (2002) A gene from Aspergillus nidulans with similarity to URE2 of Saccharomyces cerevisiae encodes a glutathione S-transferase which contributes to heavy metal and xenobiotic resistance. Appl Environ Microbiol 68: 2802-2808.
    • (2002) Appl Environ Microbiol , vol.68 , pp. 2802-2808
    • Fraser, J.A.1    Davis, M.A.2    Hynes, M.J.3
  • 84
    • 0035156642 scopus 로고    scopus 로고
    • Structure of the globular region of the prion protein Ure2 from the yeast Saccharomyces cerevisiae
    • Bousset L, Belrhali H, Janin J, Melki R, Morera S, (2001) Structure of the globular region of the prion protein Ure2 from the yeast Saccharomyces cerevisiae. Structure 9: 39-46.
    • (2001) Structure , vol.9 , pp. 39-46
    • Bousset, L.1    Belrhali, H.2    Janin, J.3    Melki, R.4    Morera, S.5
  • 85
    • 0035852745 scopus 로고    scopus 로고
    • The crystal structure of the nitrogen regulation fragment of the yeast prion protein Ure2p
    • Umland TC, Taylor KL, Rhee S, Wickner RB, Davies DR, (2001) The crystal structure of the nitrogen regulation fragment of the yeast prion protein Ure2p. Proc Natl Acad Sci U S A 98: 1459-1464.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 1459-1464
    • Umland, T.C.1    Taylor, K.L.2    Rhee, S.3    Wickner, R.B.4    Davies, D.R.5
  • 86
    • 0026728801 scopus 로고
    • Nondissociation of GAL4 and GAL80 in vivo after galactose induction
    • Leuther KK, Johnston SA, (1992) Nondissociation of GAL4 and GAL80 in vivo after galactose induction. Science 256: 1333-1335.
    • (1992) Science , vol.256 , pp. 1333-1335
    • Leuther, K.K.1    Johnston, S.A.2
  • 87
    • 0027394585 scopus 로고
    • Genetic evidence that an activation domain of GAL4 does not require acidity and may form a beta sheet
    • Leuther KK, Salmeron JM, Johnston SA, (1993) Genetic evidence that an activation domain of GAL4 does not require acidity and may form a beta sheet. Cell 72: 575-585.
    • (1993) Cell , vol.72 , pp. 575-585
    • Leuther, K.K.1    Salmeron, J.M.2    Johnston, S.A.3
  • 88
    • 0023408657 scopus 로고
    • In vivo DNA-binding properties of a yeast transcription activator protein
    • Selleck SB, Majors JE, (1987) In vivo DNA-binding properties of a yeast transcription activator protein. Mol Cell Biol 7: 3260-3267.
    • (1987) Mol Cell Biol , vol.7 , pp. 3260-3267
    • Selleck, S.B.1    Majors, J.E.2
  • 89
    • 0031795806 scopus 로고    scopus 로고
    • Deletion of the 389 N-terminal residues of the transcriptional activator AREA does not result in nitrogen metabolite derepression in Aspergillus nidulans
    • Caddick MX, Arst HN Jr, (1998) Deletion of the 389 N-terminal residues of the transcriptional activator AREA does not result in nitrogen metabolite derepression in Aspergillus nidulans. J Bacteriol 180: 5762-5764.
    • (1998) J Bacteriol , vol.180 , pp. 5762-5764
    • Caddick, M.X.1    Arst Jr., H.N.2
  • 90
    • 0030660402 scopus 로고    scopus 로고
    • Deletion of the N-terminal region of the AREA protein is correlated with a derepressed phenotype with respect to nitrogen metabolite repression
    • Lamb HK, Dodds AL, Swatman DR, Cairns E, Hawkins AR, (1997) Deletion of the N-terminal region of the AREA protein is correlated with a derepressed phenotype with respect to nitrogen metabolite repression. J Bacteriol 179: 6649-6656.
    • (1997) J Bacteriol , vol.179 , pp. 6649-6656
    • Lamb, H.K.1    Dodds, A.L.2    Swatman, D.R.3    Cairns, E.4    Hawkins, A.R.5
  • 91
    • 77957818583 scopus 로고    scopus 로고
    • The bZIP transcription factor MeaB mediates nitrogen metabolite repression at specific loci
    • Wagner D, Schmeinck A, Mos M, Morozov IY, Caddick MX, et al. (2010) The bZIP transcription factor MeaB mediates nitrogen metabolite repression at specific loci. Eukaryot Cell 9: 1588-1601.
    • (2010) Eukaryot Cell , vol.9 , pp. 1588-1601
    • Wagner, D.1    Schmeinck, A.2    Mos, M.3    Morozov, I.Y.4    Caddick, M.X.5
  • 92
    • 84863012334 scopus 로고    scopus 로고
    • Adaptation of Cryptococcus neoformans to mammalian hosts: integrated regulation of metabolism and virulence
    • In press
    • Kronstad J, Saikia S, Nielson ED, Kretschmer M, Jung W, et al. (2011) Adaptation of Cryptococcus neoformans to mammalian hosts: integrated regulation of metabolism and virulence. Eukaryot Cell In press.
    • (2011) Eukaryot Cell
    • Kronstad, J.1    Saikia, S.2    Nielson, E.D.3    Kretschmer, M.4    Jung, W.5
  • 93
    • 62349130224 scopus 로고    scopus 로고
    • Estimation of the current global burden of cryptococcal meningitis among persons living with HIV/AIDS
    • Park BJ, Wannemuehler KA, Marston BJ, Govender N, Pappas PG, et al. (2009) Estimation of the current global burden of cryptococcal meningitis among persons living with HIV/AIDS. AIDS 23: 525-530.
    • (2009) AIDS , vol.23 , pp. 525-530
    • Park, B.J.1    Wannemuehler, K.A.2    Marston, B.J.3    Govender, N.4    Pappas, P.G.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.