Foxm1 induces a global methylation signature that mimics the cancer epigenome in head and neck squamous cell carcinoma

PLoS ONE

Volumn 7, Issue 3, 2012, Pages

  Teh, Muy Teck ^a   Gemenetzidis, Emilios ^a   Patel, Deeviyaben ^a   Tariq, Rameez ^a   Nadir, Ayesha ^a   Bahta, Adiam W ^a   Waseem, Ahmad ^a   Hutchison, Iain L ^b  

^a QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^b ST BARTHOLOMEW S HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BISULFITE; DNA METHYLTRANSFERASE 1; MESSENGER RNA; SMALL INTERFERING RNA; CYCLIN DEPENDENT KINASE INHIBITOR 2A; DNA (CYTOSINE 5 ) METHYLTRANSFERASE 1; DNA (CYTOSINE 5) METHYLTRANSFERASE; DNA (CYTOSINE-5-)-METHYLTRANSFERASE 1; DNA METHYLTRANSFERASE 3A; FORKHEAD TRANSCRIPTION FACTOR; FOXM1 PROTEIN, HUMAN; HELICASE; HELLS PROTEIN, HUMAN;

ARTICLE; BMI1 GENE; CANCER CELL CULTURE; CANCER GENETICS; CANCER GROWTH; CDKN2A GENE; CONTROLLED STUDY; DNA METHYLATION; DNMT1 GENE; DNMT3B GENE; DOWN REGULATION; EPIGENETICS; FOXM1 GENE; GENE; GENE EXPRESSION REGULATION; GENE INTERACTION; GENETIC CORRELATION; GENETIC MARKER; HEAD AND NECK CARCINOMA; HELLS GENE; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VIVO STUDY; KERATINOCYTE; MICROARRAY ANALYSIS; ONCOGENE; PROMOTER REGION; QUANTITATIVE STUDY; REAL TIME POLYMERASE CHAIN REACTION; SQUAMOUS CELL CARCINOMA; TUMOR BIOPSY; TUMOR SUPPRESSOR GENE; UPREGULATION; CELL CULTURE; GENE EXPRESSION PROFILING; GENETICS; HEAD AND NECK TUMOR; IMMUNOBLOTTING; METABOLISM; PATHOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; TUMOR CELL LINE;

CARCINOMA, SQUAMOUS CELL; CELL LINE, TUMOR; CELLS, CULTURED; CYCLIN-DEPENDENT KINASE INHIBITOR P16; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; DNA HELICASES; DNA METHYLATION; EPIGENOMICS; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION PROFILING; HEAD AND NECK NEOPLASMS; HUMANS; IMMUNOBLOTTING; PROMOTER REGIONS, GENETIC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE;

EID: 84858831140     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0034329     Document Type: Article

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