Tissue engineering of oral dysplasia

Journal of Pathology

Volumn 215, Issue 3, 2008, Pages 280-289

  Gaballah, K ^a   Costea, D E ^b   Hills, A ^a   Gollin, S M ^c   Harrison, P ^d   Partridge, M ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF BERGEN   (Norway)

^c UNIVERSITY OF PITTSBURGH CANCER INSTITUTE   (United States)

^d BEATSON INSTITUTE FOR CANCER RESEARCH   (United Kingdom)

Author keywords

Dysplasia; Epithelial connective tissue interaction tissue engineering; Epithelial mesenchymal interaction; Organotypic culture; Pre cancer

Indexed keywords

GELATINASE B; SCATTER FACTOR;

ARTICLE; CELL CULTURE; CELL ISOLATION; CELL PROLIFERATION; CELL ULTRASTRUCTURE; CONTROLLED STUDY; DISEASE SEVERITY; DYSPLASIA; EPITHELIUM CELL; FIBROBLAST; HUMAN; HUMAN CELL; IMMUNOPHENOTYPING; KERATINOCYTE; MOUTH DISEASE; PRECANCER; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; TISSUE ENGINEERING;

CULTURE MEDIA, CONDITIONED; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENZYME-LINKED IMMUNOSORBENT ASSAY; FIBROBLASTS; HUMANS; HYPERPLASIA; IMMUNOHISTOCHEMISTRY; KERATINOCYTES; KERATINS; LEUKOPLAKIA, ORAL; LINEAR MODELS; MOUTH MUCOSA; PRECANCEROUS CONDITIONS; TISSUE ENGINEERING;

EID: 46849110423     PISSN: 00223417     EISSN: 10969896     Source Type: Journal    
DOI: 10.1002/path.2360     Document Type: Article

References (44)

1. Paget J. Cancer following ichthyosis of the tongue. Trans Clin Soc Lond 1870;3:88.
2. Pindborg JJ, Jolst O, Renstrup G, Roed-Petersen B. Studies in oral leukoplakia: a preliminary report on the period pervalence of malignant transformation in leukoplakia based on a follow-up study of 248 patients. J Am Dent Assoc 1968;76:767-771.
3. Shafer WG, Waldron CA. Erythroplakia of the oral cavity. Cancer 1975;36:1021-1028.
4. Scully C. Oral precancer: preventive and medical approaches to management. Oral Oncol 1995;1:16-26.
5. McGregor F, Muntoni A, Fleming J, Brown J, Felix DH, MacDonald G, et al. Molecular changes associated with oral dysplasia progression and acquisition of immortality: potential for its reversal by 5-azacytidine. Cancer Res 2002;62:4757-4766.
6. Partridge M, Pateromichelakis S, Phillips E, Emilion GG, A'Hern RP, Langdon JD. A case-control study confirms that microsatellite assay can identify patients at risk of developing oral SCC within a field of cancerisation. Cancer Res 2000;60:3893-3898.
7. Braakhuis BJM, Leemans CR, Brakenhoff RH. Expanding fields of genetically altered cells in head and neck squamous carcinogenesis. Semin Cancer Biol 2005;15:113-120.
8. Bedi GC, Westra WH, Gabrielson E, Koch W, Sidransky D. Multiple head and neck tumours, evidence for a common clonal origin. Cancer Res 1996;56:2484-2487.
9. Partridge M, Li S-R, Pateromichelakis S, Francis RA, Phillips E, Huang X-H, et al. Detection of minimal residual cancer to investigate why oral tumours recur despite seemingly adequate treatment. Clin Cancer Res 2000;6:2718-2725.
10. Mao L, El-Naggar AK, Papadimitrakopoulou V, Shin DM, Shin HC, Fan Y, et al. Phenotype and genotype of advanced premalignant head and neck lesions after chemopreventive therapy. J Natl Cancer Inst 1998;90:1545-1551.
11. Lippman SM, Hong Wk. Cancer prevention by delay. Clin Cancer Res 2002;8:305-313.
12. Rudin CM, Cohen EE, Papadimitrakopoulou VA, Silverman S, Recant W, El-Naggar AK, et al. An attenuated adenovirus, ONYX-015, as mouthwash therapy for premalignant oral dysplasia. J Clin Oncol 2003;21:4546-4552.
13. Gaballah K, Hills A, Curiel D, Hallden G, Harrison P, Partridge M. Lysis of dysplastic but not normal oral keratinocytes and tissue-engineered epithelia with conditionally replicating adenoviruses. Cancer Res 2007;67:7284-7294.
14. Partridge M, Green MR, Langdon JD, Feldmann M. Production of TGFα and TGFβ by cultured keratinocytes, skin and oral squamous cell carcinomas - potential autocrine regulation of normal and malignant epithelial cell proliferation. Br J Cancer 1989;60:542-548.
15. Rhee JC, Khuri FR, Shin DM. Emerging drugs for head and neck cancer. Expert Opin Emerg Drugs 2004;9:91-104.
16. Prime SS, Malamos D, Rosser T, Scully C. Oral epithelial atypia and acantholytic dyskeratosis in rats painted with 4-nitroquinoline N-oxide. J Oral Pathol Med 1986;15:280-283.
17. Nakao Y, Yang X, Yokoyama M, Pater MM, Pater A. Malignant transformation of human endocervical cells by HPV18: in vitro model of carcinogenesis by cigarette smoke. Carcinogenesis 1996;17:577-583.
18. Aasen T, Hodgins MB, Edward M, Graham SV. The relationship between connexins, gap junctions, tissue architecture and tumour invasion as studied in a novel in vitro model of HPV 16-associated cervical cancer progression. Oncogene 2003;22:7969-7980.
19. Margulis A, Andriani F, Fusenig N, Hashimoto K, Hanakawa Y, Garlick JA. Abrogation of E-cadherin-mediated adhesion induces tumour cell invasion in human skin-like organotypic culture. J Invest Dermatol 2003;121:1182- 1190.
20. Javaherian A, Vaccariello M, Fusenig N, Garlick JA. Normal keratinocytes suppress early stages of neoplastic progression in stratified epithelium. Cancer Res 1998;58:200-2208.
21. Vaccariello M, Javaherian A, Wang Y, Fusenig N, Garlick JA. Cell interactions control the fate of malignant keratinocytes in an organotypic model of early neoplasia. J Invest Dermatol 1999;113:384-391.
22. Sandalon Z, Fusenig NE, McCutcheon J, Taichman LB, Garlick JA. Suicide gene therapy for premalignant disease: a new strategy for the treatment of intraepithelial neoplasia. Gene Therapy 2001;8:232-238.
23. Andriani F, Garfield J, Fusenig N, Garlick JA. Basement membrane proteins promote progression of intraepithelial neoplasia in three-dimensional models of human stratified epithelium. Int J Cancer 2003;108:348-357.
24. Grafstrom RC. Human oral epithelium. In Culture of Epithelial Cells, 2nd edn, Freshney RI, Freshney MG (eds). Wiley-Liss: New York, 2002; 195-255.
25. Hansson A, Bloor BK, Sarang Z, Haig Y, Morgan PR, Fusenig NE, et al. Analysis of proliferation, apoptosis and keratin expression in cultured normal and immortalized human buccal keratinocytes. Eur J Oral Sci 2003;111:34-41.
26. Yoo GH, Washington J, Piechocki M, Ensley J, Shibuya T, Oda D, et al. Progression of head and neck cancer in an in vitro model. Arch Otolaryngol Head Neck Surg 2000;126:1313-1318.
27. Costea DE, Loro LL, Dimba EAO, Vintermytr OK, Johannessen AC. Crucial effects of fibroblasts and keratinocyte growth factor on morphogeneis of reconstruceted human oral epithelium. J Invest Dermatol 2003;121:1479-1486.
28. Dickson MA, Hahn WC, Ino Y, Ronfard V, Wu JY, Weinberg RA, et al. Human keratinocytes that express hTERT and also bypass a p16 (INK4a)-enforced mechanism that limits life span become immortal yet retain normal growth and differentiation characteriztics. Mol Cell Biol 2000;20:1436-1447.
29. Chang SE, Foster S, Betts D, Marnock WE. DOK, a cell line established from human dysplastic oral mucosa, shows a partially transformed non-malignant phenotype. Int J Cancer 1992;52:896-902.
30. Igarashi M, Irwin CR, Locke M. Mackenzie IC. Construction of large area organotypical cultures of oral mucosa and skin. J Oral Pathol Med 2003;32:422-430.
31. Partridge M, Smith CG, Green MR. Differences between the distribution of epidermal growth factor receptor in human skin and oral mucosa, detected by immunohistology and EGF binding studies. Epithelia 1998;1:179-190.
32. Gale N, Pilch BZ, Sidransky D, El Naggar A, Westra W, Califarno J, et al. Epithelial precursor lesions. In Pathology and Genetics of Head and Neck Tumours, Barnes L, Eveson JW, Reichart P, Sidransky D (eds). IARC Press: Lyon, France, 2005; 117-190.
33. Bloor BK, Seddon SV, Morgan PR. Gene expression of differentiation- specific keratins in oral epithelia dysplasia and squamous cell carcinoma. Oral Oncol 2001;37:251-261.
34. Zoeller J, Flentje M, Sinn P, Born IA. Evaluation of AgNOR and Ki67 antigen as cell kinetic parameters in oral dysplasias and carcinomas. Anal Cell Pathol 1994;7:77-88.
35. Kushner J, Bradley G, Jordan RCK. Patterns of p53 and Ki67 protein expression in epithelial dysplasia from the floor of the mouth. J Pathol 1997;183:418-423.
36. Thompson PJ, Soames JV, Booth C, O'Shea JA. Epithelial cell proliferative activity and oral cancer progression. Cell Prolif 2002;35:110- 120.
37. Andreadis ST, Hamoen KE, Yarmush LM, Morgan JR. Keratinocyte growth factor induces hyperproliferation and delays differentiation in a skin equivalent model system. FASEB J 2001;15:898-906.
38. McKeown STW, Hyland PL, Locke M, Mackenzie IC, Irwin CR. Keratinocyte growth factor and scatter factor expression by regionally defined oral fibroblasts. Eur J Oral Sci 2003;111:42-50.
39. Elenbaas B, Weinberg RA. Heterotypic signalling between epithelial tumour cells and fibroblasts in carcinoma formation. Exp Cell Res 2001;264:169-184.
40. Cukierman E, Pankov R, Stevens DR, Yamada KM. Taking cell-matrix adhesions to the third dimension. Science 2001;294:1708-1712.
41. Masur SK, Dewal HS, Dinh TT, Erenburg I, Petridou S. Myofibroblasts differentiate when plated at low density. Proc Natl Acad Sci USA 1996;93:4219-4223.
42. Defawe OD, Kenagy RD, Choi C, Wan SYC, Deroanne C, Nusgens B, et al. MMP-9 regulates both positively and negatively collagen gel contraction: a nonproteolytic function of MMP-9. Cardiovasc Res 2005;66:402- 409.
43. Chinnathambi S, Bickenbach JR. Human skin and gingival keratinocytes show differential regulation of matrix metalloproteinases when combined with fibroblasts in three-dimensional cultures. J Periodontal 2005;76:1072-1083.
44. Rosenthal EL, Matrisan LM. Matrix metalloproteases in head and neck cancer. Head Neck 2006;28:639-648.