Filamin A, the Arp2/3 complex, and the morphology and function of cortical actin filaments in human melanoma cells

Journal of Cell Biology

Volumn 155, Issue 3, 2001, Pages 511-517

  Flanagan, Lisa A ^a   Chou, Janet ^a   Falet, Hervé ^a   Neujahr, Ralph ^a   Hartwig, John H ^a   Stossel, Thomas P ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Actin networks; Arp2 3 complex; Blebbing; Cell migration; Filamins

Indexed keywords

ACTIN; ACTIN BINDING PROTEIN; FILAMIN; FILAMIN A; UNCLASSIFIED DRUG;

ACTIN FILAMENT; ARTICLE; CELL MIGRATION; CYTOARCHITECTURE; HUMAN; HUMAN CELL; MELANOMA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; RNA TRANSLATION;

EID: 0035969247     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (23)

1. Relationship between Arp2/3 complex and barbed the barbed ends of actin filaments at the leading edge of carcinoma cells after epidermal growth factor stimulation
2. The F-actin side binding activity of the Arp2/3 complex is essential for actin nucleation and lamellipod extension
3. Actin polymerization and intracellular solvent flow in cell surface blebbing
4. Actin-binding protein requirement for cortical stability and efficient locomotion
5. Activation of the CDC42 effector N-WASP by the Shigella flexneri IcsA protein promotes actin nucleation by Arp2/3 complex and bacterial actin-based motility
6. Human endothelial actin-binding protein (ABP, nonmuscle filamin): A molecular leaf spring
7. Mechanisms of actin rearrangements mediating platelet activation
8. The architecture of actin filaments and the ultrastructural location of actin-binding protein in the periphery of lung macrophages
9. Actin-binding protein promotes the bipolar and perpendicular branching of actin filaments
10. Assocarion of gelsolin with actin filaments and cell membranes of macrophages and platelets
11. Filament organization revealed in platinum replicas of freeze-dried cytoskeletons
12. Regulation of actin filament network formation through Arp2/3 complex: Activation by a diverse array of proteins
13. Nerve growth cone lamellipodia contain two populations of actin filaments that differ in organization and polarity
14. The three dimensional structure of actin filaments in solution and an actin gel made with actin-binding protein
15. The small GTPase Ra1A targets filamin to induce filopodia
16. Actin filament organization in the fish keratocyte lamellipodium
17. Filamins: Integrators of cell mechanics and signaling
18. Arp2/3 complex and actin depolymerizing factor/cofilin in dendritic organization and treadmilling of actin filament array in lamellipodia
19. Analysis of the actin-myosin II system in fish epidermal keratocytes: Mechanism of cell body translocation
20. Structural and functional aspects of filamins
21. Indications for a novel muscular dystrophy pathway: γ-filamin, the muscle-specific filamin isoform, interacts with myotilin
22. Cortactin promotes and stabilizes Arp2/3-induced actin filament network formation
23. The human Arp2/3 complex is composed of evolutionarily conserved subunits and is localized to cellular regions of dynamic actin filament assembly